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DK3261640T3 - 5ht-agonister til behandling af epilepsilidelser - Google Patents

5ht-agonister til behandling af epilepsilidelser Download PDF

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Publication number
DK3261640T3
DK3261640T3 DK16756282.6T DK16756282T DK3261640T3 DK 3261640 T3 DK3261640 T3 DK 3261640T3 DK 16756282 T DK16756282 T DK 16756282T DK 3261640 T3 DK3261640 T3 DK 3261640T3
Authority
DK
Denmark
Prior art keywords
agonists
treatment
epilepsy disorders
epilepsy
disorders
Prior art date
Application number
DK16756282.6T
Other languages
English (en)
Inventor
Scott C Baraban
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Application granted granted Critical
Publication of DK3261640T3 publication Critical patent/DK3261640T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK16756282.6T 2015-02-25 2016-02-24 5ht-agonister til behandling af epilepsilidelser DK3261640T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562120726P 2015-02-25 2015-02-25
PCT/US2016/019368 WO2016138138A1 (en) 2015-02-25 2016-02-24 5ht agonists for treating disorders

Publications (1)

Publication Number Publication Date
DK3261640T3 true DK3261640T3 (da) 2022-07-11

Family

ID=56789223

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16756282.6T DK3261640T3 (da) 2015-02-25 2016-02-24 5ht-agonister til behandling af epilepsilidelser

Country Status (21)

Country Link
US (4) US10874643B2 (da)
EP (3) EP3261640B1 (da)
JP (5) JP6884703B2 (da)
KR (3) KR102385665B1 (da)
CN (2) CN113546174A (da)
AU (3) AU2016222804C1 (da)
BR (1) BR112017018297B1 (da)
CA (2) CA2977135C (da)
CY (1) CY1125360T1 (da)
DK (1) DK3261640T3 (da)
EA (2) EA201791882A1 (da)
ES (1) ES2920886T3 (da)
HR (1) HRP20220822T1 (da)
HU (1) HUE059559T2 (da)
LT (1) LT3261640T (da)
PL (1) PL3261640T3 (da)
PT (1) PT3261640T (da)
RS (1) RS63426B1 (da)
SI (1) SI3261640T1 (da)
SM (1) SMT202200276T1 (da)
WO (1) WO2016138138A1 (da)

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Also Published As

Publication number Publication date
US20180028499A1 (en) 2018-02-01
EP4043016B1 (en) 2025-10-29
RS63426B1 (sr) 2022-08-31
SMT202200276T1 (it) 2022-09-14
CA2977135A1 (en) 2016-09-01
WO2016138138A1 (en) 2016-09-01
CA3204599A1 (en) 2016-09-01
EA201992474A2 (ru) 2020-02-28
AU2016222804B2 (en) 2021-07-15
US10874643B2 (en) 2020-12-29
SI3261640T1 (sl) 2022-10-28
ES2920886T3 (es) 2022-08-11
KR20230152844A (ko) 2023-11-03
AU2021204261B2 (en) 2023-08-10
HUE059559T2 (hu) 2022-12-28
EP4043016A1 (en) 2022-08-17
EP3261640B1 (en) 2022-04-06
PL3261640T3 (pl) 2022-10-31
KR20170118870A (ko) 2017-10-25
EP3261640A1 (en) 2018-01-03
JP2024009839A (ja) 2024-01-23
AU2022203274A1 (en) 2022-06-16
CN113546174A (zh) 2021-10-26
BR112017018297A2 (pt) 2018-04-17
BR112017018297B1 (pt) 2023-12-05
US20200147048A1 (en) 2020-05-14
CN107530326A (zh) 2018-01-02
KR102385665B1 (ko) 2022-04-14
US20210154171A1 (en) 2021-05-27
AU2016222804C1 (en) 2021-10-14
EA201992474A3 (ru) 2020-05-31
JP2018506555A (ja) 2018-03-08
CA2977135C (en) 2023-08-22
JP2020143087A (ja) 2020-09-10
JP2022116307A (ja) 2022-08-09
JP6884703B2 (ja) 2021-06-09
AU2021204261A1 (en) 2021-07-29
AU2022203274B2 (en) 2024-08-15
HRP20220822T1 (hr) 2022-10-28
EP3632434A1 (en) 2020-04-08
PT3261640T (pt) 2022-07-06
US11648237B2 (en) 2023-05-16
JP2021185148A (ja) 2021-12-09
CN107530326B (zh) 2021-09-21
KR20220048045A (ko) 2022-04-19
US20230346750A1 (en) 2023-11-02
EA201791882A1 (ru) 2018-02-28
LT3261640T (lt) 2022-07-11
EP3261640A4 (en) 2018-12-19
CY1125360T1 (el) 2025-05-09
US12447144B2 (en) 2025-10-21
AU2016222804A1 (en) 2017-08-31

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