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DK3260541T3 - Kunstige nukleinsyremolekyler til forbedret protein- eller preptidekspression - Google Patents

Kunstige nukleinsyremolekyler til forbedret protein- eller preptidekspression Download PDF

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Publication number
DK3260541T3
DK3260541T3 DK17001061.5T DK17001061T DK3260541T3 DK 3260541 T3 DK3260541 T3 DK 3260541T3 DK 17001061 T DK17001061 T DK 17001061T DK 3260541 T3 DK3260541 T3 DK 3260541T3
Authority
DK
Denmark
Prior art keywords
preptide
expression
nucleic acid
acid molecules
artificial nucleic
Prior art date
Application number
DK17001061.5T
Other languages
English (en)
Inventor
Andreas Thess
Original Assignee
Curevac Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curevac Ag filed Critical Curevac Ag
Application granted granted Critical
Publication of DK3260541T3 publication Critical patent/DK3260541T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression

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  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK17001061.5T 2012-03-27 2013-03-27 Kunstige nukleinsyremolekyler til forbedret protein- eller preptidekspression DK3260541T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP2012001336 2012-03-27
EP2012002447 2012-06-08
EP13716727.6A EP2831241B1 (en) 2012-03-27 2013-03-27 Artificial nucleic acid molecules for improved protein or peptide expression

Publications (1)

Publication Number Publication Date
DK3260541T3 true DK3260541T3 (da) 2019-08-12

Family

ID=52114010

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17001061.5T DK3260541T3 (da) 2012-03-27 2013-03-27 Kunstige nukleinsyremolekyler til forbedret protein- eller preptidekspression

Country Status (2)

Country Link
EP (3) EP3578659B1 (da)
DK (1) DK3260541T3 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3548005A4 (en) 2016-11-29 2020-06-17 Puretech Health LLC Exosomes for delivery of therapeutic agents
CN115811986A (zh) 2020-04-22 2023-03-17 生物技术欧洲股份公司 冠状病毒疫苗
US12186387B2 (en) 2021-11-29 2025-01-07 BioNTech SE Coronavirus vaccine
WO2024002985A1 (en) 2022-06-26 2024-01-04 BioNTech SE Coronavirus vaccine
CN116004696B (zh) * 2023-02-01 2024-03-29 郑州贝贝生物科技有限公司 可与IRES组合的3ˊUTR加茎环结构基因及其应用、mRNA表达系统

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6423885B1 (en) 1999-08-13 2002-07-23 Commonwealth Scientific And Industrial Research Organization (Csiro) Methods for obtaining modified phenotypes in plant cells
ATE291925T1 (de) 2001-06-05 2005-04-15 Curevac Gmbh Stabilisierte mrna mit erhöhtem g/c-gehalt und optimierter codon usage für die gentherapie
WO2012019630A1 (en) * 2010-08-13 2012-02-16 Curevac Gmbh Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded protein

Also Published As

Publication number Publication date
EP3578659B1 (en) 2023-11-01
EP2831241A1 (en) 2015-02-04
EP3260541B1 (en) 2019-05-15
EP3578659A1 (en) 2019-12-11
EP2831241B1 (en) 2017-08-23
EP3260541A1 (en) 2017-12-27

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