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DK3247699T3 - PROCESS FOR PRODUCTION OF 2- [4- (CYCLOPROPANCARBONYL) PHENYL] -2-METHYL-PROPANNITRIL - Google Patents

PROCESS FOR PRODUCTION OF 2- [4- (CYCLOPROPANCARBONYL) PHENYL] -2-METHYL-PROPANNITRIL Download PDF

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Publication number
DK3247699T3
DK3247699T3 DK16701157.6T DK16701157T DK3247699T3 DK 3247699 T3 DK3247699 T3 DK 3247699T3 DK 16701157 T DK16701157 T DK 16701157T DK 3247699 T3 DK3247699 T3 DK 3247699T3
Authority
DK
Denmark
Prior art keywords
propannitril
cyclopropancarbonyl
phenyl
methyl
production
Prior art date
Application number
DK16701157.6T
Other languages
Danish (da)
Inventor
Hermut Wehlan
Kai Rossen
Alexander Schaefer
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Application granted granted Critical
Publication of DK3247699T3 publication Critical patent/DK3247699T3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/30Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK16701157.6T 2015-01-22 2016-01-21 PROCESS FOR PRODUCTION OF 2- [4- (CYCLOPROPANCARBONYL) PHENYL] -2-METHYL-PROPANNITRIL DK3247699T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15152101 2015-01-22
PCT/EP2016/051223 WO2016116555A1 (en) 2015-01-22 2016-01-21 Process for the production of 2-[4-(cyclopropanecarbonyl)phenyl]-2-methyl-propanenitrile

Publications (1)

Publication Number Publication Date
DK3247699T3 true DK3247699T3 (en) 2019-08-12

Family

ID=52394944

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16701157.6T DK3247699T3 (en) 2015-01-22 2016-01-21 PROCESS FOR PRODUCTION OF 2- [4- (CYCLOPROPANCARBONYL) PHENYL] -2-METHYL-PROPANNITRIL

Country Status (12)

Country Link
US (1) US10336698B2 (en)
EP (1) EP3247699B1 (en)
CN (1) CN107428678B (en)
CA (1) CA2974449C (en)
DK (1) DK3247699T3 (en)
ES (1) ES2738630T3 (en)
HR (1) HRP20191146T1 (en)
HU (1) HUE044642T2 (en)
PL (1) PL3247699T3 (en)
PT (1) PT3247699T (en)
RS (1) RS58961B1 (en)
WO (1) WO2016116555A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10696633B2 (en) * 2015-10-22 2020-06-30 Sanofi-Aventis Deutschland Gmbh Process for the preparation of fexofenadine and of intermediates used therein
WO2019232294A1 (en) * 2018-06-01 2019-12-05 Cornell University Metal-chelating compositions and their use in methods of removing or inhibiting barium scale

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4254129A (en) 1979-04-10 1981-03-03 Richardson-Merrell Inc. Piperidine derivatives
JPS60130561A (en) 1983-12-16 1985-07-12 Torii Yakuhin Kk Amidine derivative and cardiotonic agent containing the same
DE3839170A1 (en) 1988-11-19 1990-05-31 Bayer Ag CYCLOPROPYL-SUBSTITUTED AZOLYLMETHYL CARBINOLES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS
KR100333790B1 (en) 1993-06-25 2002-11-04 메렐 파마슈티칼스 인크. New Intermediates for Antihistamine 4-Diphenylmethyl / Diphenylmethoxypiperidine Derivatives
US5420322A (en) 1994-08-31 1995-05-30 Mine Safety Appliances Company Preparation of alkali-metal hexamethydisilazanes
US6303782B1 (en) 1999-04-20 2001-10-16 Pfizer Inc Process for preparing benzylnitriles
GB0018691D0 (en) 2000-07-28 2000-09-20 Rolabo Sl Process
US20050222154A1 (en) 2004-04-05 2005-10-06 Hartmut Rehwinkel Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
CN1953965B (en) 2004-05-18 2012-07-04 霍夫曼-拉罗奇有限公司 Novel cis-imidazolines
CN101166722A (en) 2005-04-29 2008-04-23 惠氏公司 Process for preparing 3,3-disubstituted oxindole and thiooxindole
DE102005045132A1 (en) 2005-09-22 2007-03-29 Archimica Gmbh Process for the preparation of 2-arylcarbonyl compounds, 2-aryl esters and 2-aryl nitriles and their heteroaromatic analogs
GB0705656D0 (en) 2007-03-23 2007-05-02 Addex Pharmaceuticals Sa Novel compounds E1
WO2009001127A1 (en) 2007-06-26 2008-12-31 Astrazeneca Ab Cyanocyclopropylcarboxamides as cathepsin inhibitors
CA2807005C (en) 2010-08-05 2015-04-07 Ah Usa 42 Llc Isoxazoline derivatives as antiparasitic agents
WO2013024078A1 (en) 2011-08-17 2013-02-21 F. Hoffmann-La Roche Ag Inhibitors of bruton's tyrosine kinase
CA2891634A1 (en) 2012-11-30 2014-06-05 F. Hoffmann-La Roche Ag Inhibitors of bruton's tyrosine kinase

Also Published As

Publication number Publication date
RS58961B1 (en) 2019-08-30
US10336698B2 (en) 2019-07-02
ES2738630T3 (en) 2020-01-24
US20170369440A1 (en) 2017-12-28
CN107428678B (en) 2021-01-01
CA2974449C (en) 2023-08-29
HRP20191146T1 (en) 2019-10-04
HUE044642T2 (en) 2019-11-28
PL3247699T3 (en) 2019-11-29
EP3247699B1 (en) 2019-05-15
PT3247699T (en) 2019-08-06
WO2016116555A1 (en) 2016-07-28
CA2974449A1 (en) 2016-07-28
CN107428678A (en) 2017-12-01
EP3247699A1 (en) 2017-11-29

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