[go: up one dir, main page]

DK3245988T3 - System til ultralydsforstærket transskleral levering af lægemidler - Google Patents

System til ultralydsforstærket transskleral levering af lægemidler Download PDF

Info

Publication number
DK3245988T3
DK3245988T3 DK16170141.2T DK16170141T DK3245988T3 DK 3245988 T3 DK3245988 T3 DK 3245988T3 DK 16170141 T DK16170141 T DK 16170141T DK 3245988 T3 DK3245988 T3 DK 3245988T3
Authority
DK
Denmark
Prior art keywords
ultrasound
enhanced
drug delivery
transscleral drug
transscleral
Prior art date
Application number
DK16170141.2T
Other languages
English (en)
Inventor
Wai Leung Langston Suen
Sin Hang Sarah Cheung
Jan Frederik Engels
Original Assignee
Sonikure Holdings Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sonikure Holdings Ltd filed Critical Sonikure Holdings Ltd
Application granted granted Critical
Publication of DK3245988T3 publication Critical patent/DK3245988T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F2009/0035—Devices for immobilising a patient's head with respect to the instrument
    • A61F2009/0043—Devices for immobilising a patient's head with respect to the instrument by supporting the instrument on the patient's head, e.g. head bands
    • A61F2009/0052—Devices for immobilising a patient's head with respect to the instrument by supporting the instrument on the patient's head, e.g. head bands the instrument being supported on the patient's eye
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0093—Ultrasound system, e.g. for inducing coagulation during eye surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3576—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0612—Eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/50—Temperature

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Medical Informatics (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicinal Preparation (AREA)
DK16170141.2T 2016-05-18 2016-05-18 System til ultralydsforstærket transskleral levering af lægemidler DK3245988T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16170141.2A EP3245988B1 (en) 2016-05-18 2016-05-18 System for ultrasound-enhanced transscleral delivery of drugs

Publications (1)

Publication Number Publication Date
DK3245988T3 true DK3245988T3 (da) 2024-01-29

Family

ID=56092725

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16170141.2T DK3245988T3 (da) 2016-05-18 2016-05-18 System til ultralydsforstærket transskleral levering af lægemidler

Country Status (15)

Country Link
US (2) US11857459B2 (da)
EP (2) EP3245988B1 (da)
JP (3) JP7048583B2 (da)
KR (2) KR102572476B1 (da)
CN (2) CN109843228B (da)
AU (2) AU2017266320B2 (da)
CA (1) CA3024209A1 (da)
DK (1) DK3245988T3 (da)
ES (1) ES2972417T3 (da)
FI (1) FI3245988T3 (da)
LT (1) LT3245988T (da)
PL (1) PL3245988T3 (da)
SG (1) SG11201810101TA (da)
WO (1) WO2017198773A2 (da)
ZA (1) ZA201807742B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9622911B2 (en) 2010-09-30 2017-04-18 Cxl Ophthalmics, Llc Ophthalmic treatment device, system, and method of use
EP2830637B1 (en) 2012-03-29 2024-08-21 Epion Therapeutics, Inc. Compositions and methods for treating or preventing diseases associated with oxidative stress
EP2830627B1 (en) 2012-03-29 2024-05-01 Epion Therapeutics, Inc. Ocular treatment solutions, delivery devices and delivery augmentation methods
DK3245988T3 (da) 2016-05-18 2024-01-29 Sonikure Holdings Ltd System til ultralydsforstærket transskleral levering af lægemidler
US11497399B2 (en) 2016-05-31 2022-11-15 Qura, Inc. Implantable intraocular pressure sensors and methods of use
EP3618927A1 (en) * 2017-05-04 2020-03-11 Sorbonne Universite Transient disruption of the blood-retinal barrier of a human and uses thereof for treating a retina disorder
US11412929B2 (en) * 2017-11-17 2022-08-16 David A Wallace System and method enabling affordable measurement, monitoring and reporting of intra-ocular pressure, combined with system for topical medication delivery, appropriate for office or home-based use
CN109859595A (zh) * 2019-01-28 2019-06-07 深圳大学 一种血管网络超声仿体及制作方法
US11602331B2 (en) * 2019-09-11 2023-03-14 GE Precision Healthcare LLC Delivery of therapeutic neuromodulation
AU2021279101A1 (en) * 2020-05-28 2023-02-02 Mupharma Pty Ltd Ultrasound mediated non-invasive drug delivery porous carriers
EP4199869A4 (en) 2020-08-21 2024-12-18 Yau, Gary Lloyd Ka Tao ULTRASOUND TREATMENT OF VITREOUS OPACITIES
KR102437239B1 (ko) * 2020-09-10 2022-08-26 장상현 초음파를 이용한 약물 전달 장치
US12201856B2 (en) * 2021-04-20 2025-01-21 Brainsonix Corporation Structures and methods for modifying ultrasound treatment
CN114085814A (zh) * 2021-11-29 2022-02-25 复旦大学附属眼耳鼻喉科医院 一种利用超声调控屏障通透性的方法
CN114305855B (zh) * 2021-12-29 2023-10-27 深圳大学 眼部给药辅助装置
CN115475326A (zh) * 2022-09-27 2022-12-16 重庆金山医疗技术研究院有限公司 一种超声波胶囊
CN117959426A (zh) * 2023-12-29 2024-05-03 温州医科大学附属眼视光医院 一种视神经局部药物靶向递送的方法和药物组合
US12485280B1 (en) * 2024-07-15 2025-12-02 Tav-Tech Ltd Unitary enhanced jet spray dermal treatment handpiece

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU591186A1 (ru) * 1976-07-23 1978-02-05 Serov Vilenin Nikolaevich Устройство дл лечени заболеваний глаз
US4976150A (en) * 1986-12-30 1990-12-11 Bethlehem Steel Corporation Ultrasonic transducers
US5016615A (en) * 1990-02-20 1991-05-21 Riverside Research Institute Local application of medication with ultrasound
US5433702A (en) 1990-06-14 1995-07-18 Opthalmocare, Inc. Phaco handpiece providing fingertip control of ultrasonic energy
US5230334A (en) 1992-01-22 1993-07-27 Summit Technology, Inc. Method and apparatus for generating localized hyperthermia
US5421816A (en) * 1992-10-14 1995-06-06 Endodermic Medical Technologies Company Ultrasonic transdermal drug delivery system
US5658892A (en) 1993-01-15 1997-08-19 The General Hospital Corporation Compound delivery using high-pressure impulse transients
US5460595A (en) 1993-06-01 1995-10-24 Dynatronics Laser Corporation Multi-frequency ultrasound therapy systems and methods
US5445611A (en) * 1993-12-08 1995-08-29 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal delivery with ultrasound and chemical enhancers
US7033598B2 (en) 1996-11-19 2006-04-25 Intrabrain International N.V. Methods and apparatus for enhanced and controlled delivery of a biologically active agent into the central nervous system of a mammal
US5906580A (en) 1997-05-05 1999-05-25 Creare Inc. Ultrasound system and method of administering ultrasound including a plurality of multi-layer transducer elements
JP4441000B2 (ja) * 1997-06-23 2010-03-24 克郎 立花 生体組織処理装置
FR2772590B1 (fr) 1997-12-18 2000-04-14 Michel Puech Utilisation d'un transducteur ultrasonore pour l'exploration echographique du segment posterieur du globe oculaire
US20060015058A1 (en) * 1998-01-08 2006-01-19 Kellogg Scott C Agents and methods for enhancement of transdermal transport
US7273458B2 (en) 1998-01-12 2007-09-25 Georgia Tech Research Corporation Method of applying acoustic energy effective to alter transport or cell viability
US6161544A (en) 1998-01-28 2000-12-19 Keratoform, Inc. Methods for accelerated orthokeratology
US6173202B1 (en) 1998-03-06 2001-01-09 Spectrx, Inc. Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue
US6322532B1 (en) * 1998-06-24 2001-11-27 3M Innovative Properties Company Sonophoresis method and apparatus
CN1310623C (zh) 1998-09-11 2007-04-18 Gr智力储备股份有限公司 用共振声能和/或共振声电磁能检测和/或影响结构的方法
US20030229331A1 (en) * 1999-11-05 2003-12-11 Pharmasonics, Inc. Methods and apparatus for uniform transcutaneous therapeutic ultrasound
US8697109B2 (en) 2000-08-16 2014-04-15 Encore Health, Llc Caged mercaptan and seleno-mercaptan compounds and methods of using them
US6579519B2 (en) 2000-09-18 2003-06-17 Registrar, University Of Delhi Sustained release and long residing ophthalmic formulation and the process of preparing the same
AU2002219490A1 (en) 2002-01-08 2003-07-24 Bio Scan Ltd. Ultrasonic transducer probe
WO2003061696A2 (en) * 2002-01-23 2003-07-31 Light Sciences Corporation Systems and methods for photodynamic therapy
US7785578B2 (en) 2002-10-11 2010-08-31 Aciont, Inc. Non-invasive ocular drug delivery
US7316664B2 (en) 2002-10-21 2008-01-08 Advanced Medical Optics, Inc. Modulated pulsed ultrasonic power delivery system and method
US7699780B2 (en) 2004-08-11 2010-04-20 Insightec—Image-Guided Treatment Ltd. Focused ultrasound system with adaptive anatomical aperture shaping
US20080177220A1 (en) 2006-01-06 2008-07-24 The Curators Of The University Of Missouri Ultrasound-Mediated Transcleral Drug Delivery
GB2435211B (en) 2006-01-25 2009-08-26 Alan Whitmore Drug delivery system
US9067060B2 (en) 2006-04-20 2015-06-30 Joseph Neev Skin treatment and hair treatment device with protruding guards
AU2014200299B2 (en) * 2006-06-15 2015-04-02 Polypharma Pty Ltd A delivery system and process
US20090209899A1 (en) 2006-06-15 2009-08-20 Harry Unger Delivery system and process
US20100057060A1 (en) 2007-12-07 2010-03-04 Seros Medical, Llc In Situ UV/Riboflavin Ocular Treatment System
EP2092916A1 (en) * 2008-02-19 2009-08-26 Institut National De La Sante Et De La Recherche Medicale (Inserm) A method of treating an ocular pathology by applying high intensity focused ultrasound and device thereof
US20100143241A1 (en) * 2008-10-22 2010-06-10 Johnson G Allan Method and apparatus for delivery of agents across the blood brain barrier
AU2009313415B2 (en) 2008-11-07 2015-01-15 Johnson & Johnson Surgical Vision, Inc. Multiple frequency phacoemulsification needle driver
EP2398432B1 (en) * 2009-02-18 2017-09-06 Eye Tech Care Ultrasound device comprising means to generate ultrasound beam presenting a concave segment shape having a single curvature
US9314421B2 (en) 2009-03-06 2016-04-19 The Hong Kong University Of Science And Technology Ultrasound-enhanced intrascleral delivery of macromolecules
US10258563B2 (en) 2009-04-20 2019-04-16 Drexel University Encapsulation of microbubbles within the aqueous core of microcapsules
AU2010282256A1 (en) 2009-08-14 2012-03-01 Ethicon Endo-Surgery, Inc. Ultrasonic surgical apparatus and silicon waveguide and methods for use thereof
IN2012DN02230A (da) 2009-08-18 2015-08-21 Eye Tech Care
US20110092880A1 (en) 2009-10-12 2011-04-21 Michael Gertner Energetic modulation of nerves
CN103153396A (zh) 2010-02-01 2013-06-12 蒙特法沃医疗中心 角膜胶原关联及治疗眼疾的方法和装置
US9028860B2 (en) 2010-04-28 2015-05-12 Poly-Med, Inc. Partially microcellular, selectively hydrophilic composite construct for ocular drug delivery
WO2011138783A1 (en) 2010-05-05 2011-11-10 Technion Research & Development Foundation Ltd. Method and system of manipulating bilayer membranes
US8721572B1 (en) 2010-06-10 2014-05-13 Eyedetec Medical, Inc. Systems, devices, kits and methods for therapy of the eye
JP5734620B2 (ja) 2010-10-27 2015-06-17 オリンパス株式会社 超音波プローブ装置及びその制御方法
US9308126B2 (en) 2010-11-29 2016-04-12 The Regents Of The University Of Colorado, A Body Corporate Non-invasive devices and methods for lowering intra-ocular pressure
KR20130139319A (ko) * 2010-12-31 2013-12-20 보오슈 앤드 롬 인코포레이팃드 안압 안정화 장치를 갖는 안과 수술 시스템
CA2814874C (en) 2011-01-12 2017-10-10 Sooft Italia Spa Device for corneal delivery of riboflavin by iontophoresis for the treatment of keratoconus
FR2973685B1 (fr) 2011-04-05 2014-11-28 Eye Tech Care Dispositif de therapie oculaire par ultrasons a reflecteur
EP2572740A1 (en) * 2011-09-20 2013-03-27 Roche Diagnostics GmbH Drug injection devices and systems with an analyte measurement module
FR2983700B1 (fr) 2011-12-08 2014-03-07 Eye Tech Care Dispositif de succion pour le traitement d'une pathologie oculaire
US9125722B2 (en) 2012-02-09 2015-09-08 Donald N. Schwartz Device for the ultrasonic treatment of glaucoma having a concave tip
CA2865132A1 (en) 2012-02-22 2013-08-29 Trustees Of Tufts College Compositions and methods for ocular delivery of a therapeutic agent
US20150173949A1 (en) 2012-07-03 2015-06-25 Doheny Eye Institute Sonolysis method
US9612227B2 (en) * 2012-10-31 2017-04-04 Hitachi, Ltd. Ultrasonic probe
CN204017181U (zh) 2013-03-08 2014-12-17 奥赛拉公司 美学成像与处理系统、多焦点处理系统和执行美容过程的系统
US9597227B2 (en) * 2013-03-15 2017-03-21 Abbott Medical Optics Inc. Trans-sclera portal for delivery of therapeutic agents
CA2999499C (en) * 2013-03-15 2020-04-07 Sonovia Holdings Llc Light and ultrasonic transducer device
CA2942919A1 (en) 2013-03-15 2014-09-18 Doheny Eye Institute Management of tractional membranes
JP2016518932A (ja) 2013-05-06 2016-06-30 ミューファーマ ピーティーワイ リミテッド 非侵襲的薬剤アプリケータ
US20160199029A1 (en) 2013-08-19 2016-07-14 University Of Utah Research Foundation Ultrasound apparatus, system, and method
CN203494051U (zh) 2013-09-11 2014-03-26 成都锐联科技有限公司 一种经皮给药治疗仪
CA2871205A1 (en) * 2013-11-15 2015-05-15 Matthew BUJAK Method, system and use for therapeutic ultrasound
US20150174387A1 (en) * 2013-12-23 2015-06-25 L'oreal Combined sonic and ultrasonic skin care device
CN106572919B (zh) 2014-06-27 2020-06-02 Tec晶体有限责任公司 用于角膜胶原交联的实时声学剂量测定
PT3721868T (pt) 2015-01-26 2022-08-12 Bausch & Lomb Composição para suspensão oftálmica
DK3245988T3 (da) 2016-05-18 2024-01-29 Sonikure Holdings Ltd System til ultralydsforstærket transskleral levering af lægemidler
US11305133B2 (en) * 2017-03-31 2022-04-19 The Board Of Trustees Of The Leland Stanford Junior University Efficient acoustic energy transfer through skull via excitation of Lamb waves

Also Published As

Publication number Publication date
JP7317916B2 (ja) 2023-07-31
KR102425704B1 (ko) 2022-07-28
US11857459B2 (en) 2024-01-02
BR112018073791A2 (pt) 2019-02-26
CN109843228A (zh) 2019-06-04
US20190083306A1 (en) 2019-03-21
CA3024209A1 (en) 2017-11-23
SG11201810101TA (en) 2018-12-28
KR20190029530A (ko) 2019-03-20
KR20220112850A (ko) 2022-08-11
AU2023203148A1 (en) 2023-06-08
CN109843228B (zh) 2022-07-08
KR102572476B1 (ko) 2023-08-29
CN115252276A (zh) 2022-11-01
AU2017266320A1 (en) 2018-12-06
EP3458000A2 (en) 2019-03-27
WO2017198773A2 (en) 2017-11-23
PL3245988T3 (pl) 2024-05-27
EP3245988A1 (en) 2017-11-22
JP2019516534A (ja) 2019-06-20
JP2023060338A (ja) 2023-04-27
AU2023203148B2 (en) 2025-05-01
AU2017266320B2 (en) 2023-03-16
ZA201807742B (en) 2022-07-27
ES2972417T3 (es) 2024-06-12
EP3245988B1 (en) 2023-12-27
JP7048583B2 (ja) 2022-04-05
WO2017198773A3 (en) 2017-12-28
CN115252276B (zh) 2025-11-11
LT3245988T (lt) 2024-02-12
US20240164941A1 (en) 2024-05-23
JP7463584B2 (ja) 2024-04-08
FI3245988T3 (fi) 2024-02-22
JP2022001290A (ja) 2022-01-06

Similar Documents

Publication Publication Date Title
DK3245988T3 (da) System til ultralydsforstærket transskleral levering af lægemidler
DK3463248T3 (da) Anordnnger til anvendelse af lægemiddelanordninger
DK3302638T3 (da) Anordning til indgivelse af lægemidler
DK3581226T3 (da) Systemer til levering af terapeutisk gas
DK3703784T3 (da) Anordning til indgivelse af lægemidler
DK3522851T3 (da) System til medicineringskompliansstyring.
DK3361946T3 (da) Føringssystem til indføring af en medicinsk nål
EP3380061C0 (en) PORTABLE AUTOMATED MEDICATION DELIVERY SYSTEM
DK3191809T3 (da) System og fremgangsmåde til fremstilling af en farmaceutisk forbindelse
DK3265421T3 (da) Doseringssystem
DK3380154T3 (da) Anordning til injektion af lægemidler
DK3419700T3 (da) Indretning til dosiskontrol af indretning til afgivelse af injicerbar lægemiddel
DK3198035T3 (da) Fremgangsmåder til forudsigelse af medicinrespons
DK3357491T3 (da) Farmaceutisk sammensætning til afgivelse af et anionisk medikament
DK3237045T3 (da) Indretning til indgivelse af lægemidler
DK3139925T3 (da) Valbenazin-doseringssystem til behandling af hyperkinetiske bevægelsesforstyrrelser
DK3471672T3 (da) Injektionsindretning til subretinal levering af terapeutisk middel
EP3231467C0 (en) INFUSION PUMP SYSTEM
DK3092188T3 (da) Transportørsystemer til omdirigering af genstande
DK3310414T3 (da) Lægemiddeladministrationsanordning
DK3460141T3 (da) System til opretning af gelænderplader
DK3310800T3 (da) Leveringssystem til styret lægemiddelfrigivelse
DK3380139T3 (da) Medikamentadministrationsanordning
DK3331495T3 (da) Flydende polymerleveringssystem til forlænget indgivelse af lægemidler
HRP20181226T1 (hr) Tekući farmaceutski sustav