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DK31391A - Pentacycliske triterpenoidforbindelser som topoisomeraseinhibitorer eller celledifferentieringsfremkaldere - Google Patents

Pentacycliske triterpenoidforbindelser som topoisomeraseinhibitorer eller celledifferentieringsfremkaldere Download PDF

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Publication number
DK31391A
DK31391A DK031391A DK31391A DK31391A DK 31391 A DK31391 A DK 31391A DK 031391 A DK031391 A DK 031391A DK 31391 A DK31391 A DK 31391A DK 31391 A DK31391 A DK 31391A
Authority
DK
Denmark
Prior art keywords
developers
topoisomerase inhibitors
cell differential
pentacyclic triterpenoid
triterpenoid compounds
Prior art date
Application number
DK031391A
Other languages
Danish (da)
English (en)
Other versions
DK31391D0 (da
Inventor
Yue-Wei Lee
Qi-Cheng Fang
Zhen-Guo Wang
De-Hua Li
C Edgar Cook
Original Assignee
Res Triangle Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Triangle Inst filed Critical Res Triangle Inst
Publication of DK31391D0 publication Critical patent/DK31391D0/da
Publication of DK31391A publication Critical patent/DK31391A/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/02—Saturated compounds containing hydroxy or O-metal groups
    • C07C62/06—Saturated compounds containing hydroxy or O-metal groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/256—Polyterpene radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK031391A 1988-08-24 1991-02-22 Pentacycliske triterpenoidforbindelser som topoisomeraseinhibitorer eller celledifferentieringsfremkaldere DK31391A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23590388A 1988-08-24 1988-08-24
PCT/US1989/003581 WO1990001937A1 (fr) 1988-08-24 1989-08-24 Composes triterpenoïdes pentacycliques utiles comme inhibiteurs de la topo-isomerase ou comme inducteurs de la differentiation cellulaire

Publications (2)

Publication Number Publication Date
DK31391D0 DK31391D0 (da) 1991-02-22
DK31391A true DK31391A (da) 1991-02-22

Family

ID=22887334

Family Applications (1)

Application Number Title Priority Date Filing Date
DK031391A DK31391A (da) 1988-08-24 1991-02-22 Pentacycliske triterpenoidforbindelser som topoisomeraseinhibitorer eller celledifferentieringsfremkaldere

Country Status (10)

Country Link
EP (1) EP0431076B1 (fr)
JP (1) JP2828295B2 (fr)
KR (1) KR100187738B1 (fr)
CN (1) CN1041204C (fr)
AU (1) AU630374B2 (fr)
CA (1) CA1330944C (fr)
DE (1) DE68909947T2 (fr)
DK (1) DK31391A (fr)
TW (1) TW225990B (fr)
WO (1) WO1990001937A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4201903B4 (de) * 1992-01-24 2004-04-15 Hermann P.T. Prof. Dr.Med. Ammon Pharmazeutische Verwendung von Boswelliasäuren
DE4444288A1 (de) * 1994-12-13 1996-06-20 Rainer Dr Med Etzel Verwendung von Weihrauch zur Behandlung der Alzheimer-Krankheit
DE4445728A1 (de) * 1994-12-21 1996-06-27 Simmet Th Prof Dr Verwendung von Boswelliasäure zur Behandlung von Hirntumoren
DE19531067A1 (de) † 1995-08-23 1997-02-27 Hermann P T Prof Dr Med Ammon Verwendung von Boswelliasäure und ihren Derivaten zur Hemmung der normalen und gesteigerten Leukozytenelastase- oder Plasminaktivität
WO2000066111A1 (fr) * 1999-04-30 2000-11-09 Sabinsa Corporation Compositions a base d'acides boswelliques, derivees de gomme-resine de boswellia serrata et destinees a traiter des etats lymphoproliferatifs et auto-immuns
WO2002085921A2 (fr) * 2001-03-01 2002-10-31 Johann Jauch Procede simple de synthese d'acides boswelliques et de derives de ceux-ci
CN1304007C (zh) * 2002-02-04 2007-03-14 中国医学科学院药物研究所 乙酰乳香酸在制备肿瘤转移抑制剂中的应用
US8028292B2 (en) 2004-02-20 2011-09-27 Sony Computer Entertainment Inc. Processor task migration over a network in a multi-processor system
CN101796182B (zh) * 2007-06-25 2013-10-16 植物生物科学有限公司 涉及三萜合成的酶
DE102008015607A1 (de) * 2008-03-26 2009-10-15 Universität Tübingen Verwendung von Boswelliasäuren und synthetischen Boswelliasäurederivaten zur Hemmung der mikrosomalen Prostaglandin E2 Synthase und des Cathepsin G
EP2408461B1 (fr) 2009-03-17 2016-01-27 Ertelt, Herta Procédé d'extraction de résines végétales, ainsi que produits d'extraction ansi obtenus et leur utilisation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4501734A (en) * 1981-03-06 1985-02-26 Wakunaga Yakuhin Kabushiki Kaisha Promotion of absorption of drugs administered through the alimentary system

Also Published As

Publication number Publication date
CA1330944C (fr) 1994-07-26
DE68909947T2 (de) 1994-02-24
JPH04500209A (ja) 1992-01-16
AU630374B2 (en) 1992-10-29
KR100187738B1 (ko) 1999-06-01
CN1043131A (zh) 1990-06-20
DK31391D0 (da) 1991-02-22
AU4303389A (en) 1990-03-23
TW225990B (fr) 1994-07-01
KR900701280A (ko) 1990-12-01
DE68909947D1 (de) 1993-11-18
EP0431076B1 (fr) 1993-10-13
EP0431076A1 (fr) 1991-06-12
CN1041204C (zh) 1998-12-16
JP2828295B2 (ja) 1998-11-25
WO1990001937A1 (fr) 1990-03-08
EP0431076A4 (en) 1992-01-15

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