DK3117030T3 - Diagnosticering af sepsis - Google Patents
Diagnosticering af sepsis Download PDFInfo
- Publication number
- DK3117030T3 DK3117030T3 DK15761149.2T DK15761149T DK3117030T3 DK 3117030 T3 DK3117030 T3 DK 3117030T3 DK 15761149 T DK15761149 T DK 15761149T DK 3117030 T3 DK3117030 T3 DK 3117030T3
- Authority
- DK
- Denmark
- Prior art keywords
- sepsis
- diagnosis
- Prior art date
Links
- 206010040047 Sepsis Diseases 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Pathology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461953458P | 2014-03-14 | 2014-03-14 | |
| PCT/CA2015/000160 WO2015135071A1 (en) | 2014-03-14 | 2015-03-13 | Diagnostic for sepsis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3117030T3 true DK3117030T3 (da) | 2022-06-27 |
Family
ID=54070730
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15761149.2T DK3117030T3 (da) | 2014-03-14 | 2015-03-13 | Diagnosticering af sepsis |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20170073734A1 (da) |
| EP (1) | EP3117030B1 (da) |
| JP (4) | JP2017514459A (da) |
| CN (1) | CN106661765B (da) |
| AU (4) | AU2015230632A1 (da) |
| CA (1) | CA2942577A1 (da) |
| DK (1) | DK3117030T3 (da) |
| ES (1) | ES2918777T3 (da) |
| WO (1) | WO2015135071A1 (da) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019530878A (ja) | 2016-06-26 | 2019-10-24 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 重篤患者における死亡率の予後診断に使用するためのバイオマーカー |
| WO2018140256A1 (en) * | 2017-01-17 | 2018-08-02 | Duke University | Gene expression signatures useful to predict or diagnose sepsis and methods of using the same |
| CN106947820B (zh) * | 2017-04-11 | 2020-09-29 | 成都望路医药技术有限公司 | Vcan在结肠腺癌诊治中的用途 |
| CN113684275B (zh) * | 2017-06-22 | 2024-02-27 | 北海康成（北京）医药科技有限公司 | 预测食管癌对抗erbb3抗体治疗的应答的方法和试剂盒 |
| WO2019110706A1 (en) * | 2017-12-08 | 2019-06-13 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for predicting the risk of developing a sepsis or a systemic inflammatory response syndrome (sirs) |
| AU2019227186B2 (en) | 2018-02-27 | 2025-07-10 | The Board Of Trustees Of The Leland Stanford Junior University | Classifier for identification of robust sepsis subtypes |
| US11908581B2 (en) | 2018-04-10 | 2024-02-20 | Hill-Rom Services, Inc. | Patient risk assessment based on data from multiple sources in a healthcare facility |
| US11504071B2 (en) | 2018-04-10 | 2022-11-22 | Hill-Rom Services, Inc. | Patient risk assessment based on data from multiple sources in a healthcare facility |
| FR3080185A1 (fr) * | 2018-04-16 | 2019-10-18 | Biomerieux | Evaluation du risque de complication chez un patient suspecte d'avoir une infection ayant un score sofa inferieur a deux |
| CN109765202B (zh) * | 2019-01-25 | 2021-03-30 | 福州大学 | 一种快速检测细菌内毒素的方法 |
| US20220299511A1 (en) * | 2019-06-17 | 2022-09-22 | The Broad Institute, Inc. | Immune cell signature for bacterial sepsis |
| US20220283153A1 (en) * | 2019-08-05 | 2022-09-08 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Compositions and methods for detecting sepsis |
| FR3101423A1 (fr) * | 2019-10-01 | 2021-04-02 | bioMérieux | Procédé pour déterminer la capacité d’un individu à répondre à un stimulus |
| US20220381791A1 (en) * | 2019-10-01 | 2022-12-01 | bioMérieux | Method for determining an individual ability to respond to a stimulus |
| AU2021264555A1 (en) * | 2020-04-29 | 2022-11-17 | Inflammatix, Inc. | Determining mortality risk of subjects with viral infections |
| CA3221576A1 (en) | 2021-05-25 | 2022-12-01 | The University Of British Columbia | Diagnostic for sepsis endotypes and/or severity |
| CN116694568A (zh) * | 2022-03-02 | 2023-09-05 | 北京市希波生物医学技术有限责任公司 | 用于激活整体抗肿瘤免疫系统的培养基配方物及制备激动剂激活的整体免疫效应细胞的方法 |
| CN120966977A (zh) * | 2024-05-17 | 2025-11-18 | 浙江大学 | 一种诊断全身性炎症的标志物以及应用 |
| CN118581207A (zh) * | 2024-05-17 | 2024-09-03 | 浙江大学医学院附属邵逸夫医院 | 一种诊断全身性炎症的标志物以及应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA05005073A (es) * | 2002-11-12 | 2005-11-17 | Becton Dickinson Co | Diagnostico de la sepsis o sirs usando perfiles de biomarcadores. |
| US20050196817A1 (en) | 2004-01-20 | 2005-09-08 | Molecular Staging Inc. | Biomarkers for sepsis |
| EP1869463A4 (en) | 2005-04-15 | 2010-05-05 | Becton Dickinson Co | SEPSIS DIAGNOSIS |
| CN101208602A (zh) * | 2005-04-15 | 2008-06-25 | 贝克顿迪金森公司 | 脓毒症的诊断 |
| AU2006267097A1 (en) * | 2005-07-13 | 2007-01-18 | Beth Israel Deaconess Medical Center | Methods of diagnosing and treating an inflammatory response |
| DE102005050933A1 (de) | 2005-10-21 | 2007-04-26 | Justus-Liebig-Universität Giessen | Erfindung betreffend Expressionsprofile zur Vorhersage von septischen Zuständen |
| EP1950310A1 (en) * | 2007-01-23 | 2008-07-30 | Charite-Universitätsmedizin Berlin | Method for risk prediction of a postoperative sepsis in a human |
| EP2085486A1 (en) * | 2008-02-01 | 2009-08-05 | Assistance Publique - Hopitaux de Paris | Methods and kits for the rapid determination of patients at high risk of death during septic shock |
| JP5619016B2 (ja) * | 2008-10-28 | 2014-11-05 | アシスタンスピュブリック−オピトド パリＡｓｓｉｓｔａｎｃｅ Ｐｕｂｌｉｑｕｅ−Ｈｏｐｉｔａｕｘ Ｄｅ Ｐａｒｉｓ | 重症敗血症及び敗血症性ショック中の死亡の危険性が高い患者を迅速に決定するための方法及びキット |
| EP2376923A4 (en) * | 2008-12-22 | 2012-08-15 | Children S Res Inst | SEPSIE DETECTION METHOD |
| US20110076685A1 (en) | 2009-09-23 | 2011-03-31 | Sirs-Lab Gmbh | Method for in vitro detection and differentiation of pathophysiological conditions |
| US20110312521A1 (en) | 2010-06-17 | 2011-12-22 | Baylor Research Institute | Genomic Transcriptional Analysis as a Tool for Identification of Pathogenic Diseases |
| EP2520662A1 (en) * | 2011-05-04 | 2012-11-07 | Stichting Sanquin Bloedvoorziening | Means and methods to determine a risk of multiple organ failure |
| US20140162370A1 (en) * | 2011-06-14 | 2014-06-12 | The Board Of Trustees Of The Leland Stanford Junior University | Urine biomarkers for necrotizing enterocolitis and sepsis |
| WO2013152047A1 (en) | 2012-04-02 | 2013-10-10 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of sepsis |
| US10190169B2 (en) * | 2013-06-20 | 2019-01-29 | Immunexpress Pty Ltd | Biomarker identification |
| CN105473743A (zh) * | 2013-06-28 | 2016-04-06 | 睿智研究实验室私人有限公司 | 脓毒症生物标志物及其应用 |
| EP3268499B1 (en) | 2015-03-12 | 2020-05-13 | The Board of Trustees of the Leland Stanford Junior University | Methods for diagnosis of sepsis |
-
2015
- 2015-03-13 US US15/124,333 patent/US20170073734A1/en not_active Abandoned
- 2015-03-13 ES ES15761149T patent/ES2918777T3/es active Active
- 2015-03-13 CN CN201580020498.0A patent/CN106661765B/zh active Active
- 2015-03-13 CA CA2942577A patent/CA2942577A1/en active Pending
- 2015-03-13 EP EP15761149.2A patent/EP3117030B1/en active Active
- 2015-03-13 JP JP2016557954A patent/JP2017514459A/ja active Pending
- 2015-03-13 DK DK15761149.2T patent/DK3117030T3/da active
- 2015-03-13 AU AU2015230632A patent/AU2015230632A1/en not_active Abandoned
- 2015-03-13 WO PCT/CA2015/000160 patent/WO2015135071A1/en not_active Ceased
-
2019
- 2019-02-19 US US16/279,788 patent/US11851717B2/en active Active
-
2020
- 2020-03-03 AU AU2020201564A patent/AU2020201564B2/en active Active
- 2020-06-12 JP JP2020101999A patent/JP2020162615A/ja active Pending
-
2022
- 2022-02-15 JP JP2022021419A patent/JP2022065095A/ja active Pending
- 2022-09-13 AU AU2022231671A patent/AU2022231671A1/en not_active Abandoned
-
2024
- 2024-03-07 JP JP2024034848A patent/JP7703720B2/ja active Active
-
2025
- 2025-06-23 AU AU2025204709A patent/AU2025204709A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN106661765B (zh) | 2020-06-05 |
| JP2022065095A (ja) | 2022-04-26 |
| EP3117030B1 (en) | 2022-04-27 |
| AU2020201564B2 (en) | 2022-06-16 |
| US11851717B2 (en) | 2023-12-26 |
| EP3117030A1 (en) | 2017-01-18 |
| WO2015135071A1 (en) | 2015-09-17 |
| AU2020201564A1 (en) | 2020-03-19 |
| CA2942577A1 (en) | 2015-09-17 |
| EP3117030A4 (en) | 2017-10-25 |
| AU2015230632A1 (en) | 2016-10-06 |
| US20200032321A1 (en) | 2020-01-30 |
| AU2025204709A1 (en) | 2025-07-10 |
| ES2918777T3 (es) | 2022-07-20 |
| US20170073734A1 (en) | 2017-03-16 |
| JP2024069344A (ja) | 2024-05-21 |
| AU2022231671A1 (en) | 2022-10-06 |
| JP2017514459A (ja) | 2017-06-08 |
| JP2020162615A (ja) | 2020-10-08 |
| JP7703720B2 (ja) | 2025-07-07 |
| CN106661765A (zh) | 2017-05-10 |
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