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DK3105328T3 - Multiplexet genom manipulation ved hjælp af CRISPR - Google Patents

Multiplexet genom manipulation ved hjælp af CRISPR Download PDF

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Publication number
DK3105328T3
DK3105328T3 DK15749644.9T DK15749644T DK3105328T3 DK 3105328 T3 DK3105328 T3 DK 3105328T3 DK 15749644 T DK15749644 T DK 15749644T DK 3105328 T3 DK3105328 T3 DK 3105328T3
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DK
Denmark
Prior art keywords
crispr
multiplex genome
genome manipulation
manipulation
multiplex
Prior art date
Application number
DK15749644.9T
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English (en)
Inventor
Ryan T Gill
Andrew Garst
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Univ Colorado Regents
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53800598&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3105328(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Colorado Regents filed Critical Univ Colorado Regents
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Publication of DK3105328T3 publication Critical patent/DK3105328T3/da

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N15/102—Mutagenizing nucleic acids
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    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1082—Preparation or screening gene libraries by chromosomal integration of polynucleotide sequences, HR-, site-specific-recombination, transposons, viral vectors
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    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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    • C40B40/04—Libraries containing only organic compounds
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/50—Physical structure
    • C12N2310/53—Physical structure partially self-complementary or closed
    • C12N2310/531—Stem-loop; Hairpin
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    • C12N2320/00—Applications; Uses
    • C12N2320/10—Applications; Uses in screening processes
    • C12N2320/11—Applications; Uses in screening processes for the determination of target sites, i.e. of active nucleic acids
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    • C12N2320/00—Applications; Uses
    • C12N2320/10—Applications; Uses in screening processes
    • C12N2320/12—Applications; Uses in screening processes in functional genomics, i.e. for the determination of gene function
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    • C12N2330/00—Production
    • C12N2330/30—Production chemically synthesised
    • C12N2330/31—Libraries, arrays

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  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
DK15749644.9T 2014-02-11 2015-02-11 Multiplexet genom manipulation ved hjælp af CRISPR DK3105328T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461938608P 2014-02-11 2014-02-11
PCT/US2015/015476 WO2015123339A1 (en) 2014-02-11 2015-02-11 Crispr enabled multiplexed genome engineering

Publications (1)

Publication Number Publication Date
DK3105328T3 true DK3105328T3 (da) 2020-07-13

Family

ID=53800598

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15749644.9T DK3105328T3 (da) 2014-02-11 2015-02-11 Multiplexet genom manipulation ved hjælp af CRISPR

Country Status (23)

Country Link
US (16) US10266849B2 (da)
EP (4) EP3105328B1 (da)
JP (3) JP2017505145A (da)
KR (4) KR20220142547A (da)
CN (2) CN111705365B (da)
AU (2) AU2015217208B2 (da)
CA (3) CA3161903C (da)
CY (1) CY1123115T1 (da)
DE (1) DE212015000061U1 (da)
DK (1) DK3105328T3 (da)
ES (2) ES2974229T3 (da)
GB (1) GB2544382B (da)
HR (1) HRP20201040T1 (da)
HU (2) HUE049634T2 (da)
IL (2) IL246951B (da)
LT (1) LT3105328T (da)
MX (1) MX375420B (da)
PL (1) PL3105328T3 (da)
PT (1) PT3105328T (da)
RS (1) RS60492B1 (da)
SI (1) SI3105328T1 (da)
SM (1) SMT202000357T1 (da)
WO (1) WO2015123339A1 (da)

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