DK3176258T3 - Fremgangsmåde til fremstilling af dendritisk celle, dendritisk celle fremstillet derved, og anvendelse deraf - Google Patents
Fremgangsmåde til fremstilling af dendritisk celle, dendritisk celle fremstillet derved, og anvendelse deraf Download PDFInfo
- Publication number
- DK3176258T3 DK3176258T3 DK15828295.4T DK15828295T DK3176258T3 DK 3176258 T3 DK3176258 T3 DK 3176258T3 DK 15828295 T DK15828295 T DK 15828295T DK 3176258 T3 DK3176258 T3 DK 3176258T3
- Authority
- DK
- Denmark
- Prior art keywords
- dendritic cells
- procedure
- application
- manufacturing
- cells made
- Prior art date
Links
- 210000004443 dendritic cell Anatomy 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/19—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/02—Compounds of the arachidonic acid pathway, e.g. prostaglandins, leukotrienes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2301—Interleukin-1 (IL-1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2306—Interleukin-6 (IL-6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/24—Interferons [IFN]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/25—Tumour necrosing factors [TNF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases [EC 2.]
- C12N2501/727—Kinases (EC 2.7.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Oncology (AREA)
- Mycology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020140099281A KR101518972B1 (ko) | 2014-08-01 | 2014-08-01 | 수지상세포의 제조방법, 이에 의해 제조된 수지상세포 및 그 용도 |
| PCT/KR2015/007892 WO2016018053A1 (ko) | 2014-08-01 | 2015-07-28 | 수지상세포의 제조방법, 이에 의해 제조된 수지상세포 및 그 용도 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3176258T3 true DK3176258T3 (da) | 2020-06-29 |
Family
ID=53394311
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15828295.4T DK3176258T3 (da) | 2014-08-01 | 2015-07-28 | Fremgangsmåde til fremstilling af dendritisk celle, dendritisk celle fremstillet derved, og anvendelse deraf |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10478479B2 (da) |
| EP (1) | EP3176258B1 (da) |
| JP (1) | JP6602377B2 (da) |
| KR (1) | KR101518972B1 (da) |
| CN (1) | CN106604989B (da) |
| DK (1) | DK3176258T3 (da) |
| ES (1) | ES2796299T3 (da) |
| WO (1) | WO2016018053A1 (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106119231A (zh) * | 2016-06-24 | 2016-11-16 | 安徽未名细胞治疗有限公司 | 一种肿瘤抗原psa的ctl识别表位肽及其应用 |
| CN109306339A (zh) * | 2017-07-28 | 2019-02-05 | 上海市血液中心 | 一种在炎性环境下保持稳定的耐受性树突状细胞的制备方法及其应用 |
| WO2020101037A1 (ja) * | 2018-11-16 | 2020-05-22 | 株式会社Ｔｎｐパートナーズ | オーダーメイド医療基幹システム |
| CN113444688B (zh) * | 2021-06-24 | 2022-09-09 | 广西中医药大学 | 用于抗病毒抗肿瘤的人树突状细胞诱导方法及组合物 |
| KR20230099956A (ko) * | 2021-12-28 | 2023-07-05 | 제이더블유크레아젠 주식회사 | 면역세포에 항원을 전달하기 위한 폴리펩타이드 |
| CN116064399B (zh) * | 2022-07-28 | 2025-06-13 | 深圳市新合生物医疗科技有限公司 | 一种检测mRNA特异性免疫激活的方法及其应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1209226A3 (en) * | 2000-11-07 | 2002-06-05 | GSF-Forschungszentrum für Umwelt und Gesundheit GmbH | Maturation of dendritic cells by recombinant heat shock protein 70 (hsp70) |
| EP1270732A1 (en) | 2001-06-21 | 2003-01-02 | Schuler, Gerold | Improved transfection of eukaryontic cells with linear polynucleotides by electroporation |
| WO2003097671A1 (en) | 2002-03-29 | 2003-11-27 | Creagene Inc. | Cytoplasmic transduction peptides and uses thereof |
| US20050003533A1 (en) * | 2003-05-08 | 2005-01-06 | Pawel Kalinski | Mature type-1 polarized dendritic cells with enhanced IL-12 production and methods of serum-free production and use |
| JP5020935B2 (ja) | 2005-04-08 | 2012-09-05 | アルゴス セラピューティクス，インコーポレイティド | 樹状細胞組成物および方法 |
| KR100734525B1 (ko) | 2005-05-27 | 2007-07-03 | 크레아젠 주식회사 | 인간 및 비근교계 동물에서 세포독성 ｔ 임파구 활성을효과적으로 측정하는 방법 |
| KR100900742B1 (ko) * | 2007-05-17 | 2009-06-08 | 크레아젠 주식회사 | 인간 간암 동물모델 및 이를 이용한 수지상세포-유래 간암면역치료제의 예방 및 치료 효능을 분석하는 방법 |
| CA3123228A1 (en) | 2008-03-27 | 2009-10-01 | Asterias Biotherapeutics, Inc. | Differentiation of primate pluripotent stem cells to hematopoietic lineage cells |
| KR101163544B1 (ko) * | 2009-02-03 | 2012-07-06 | 제이더블유크레아젠 주식회사 | 전립선암 면역치료용 수지상 세포 제조를 위한 ｐａｐ 항원의 제조 방법 |
| CN102439137A (zh) * | 2009-03-31 | 2012-05-02 | Jw制药公司 | 具有诱导癌症特异性免疫反应的能力的树突状细胞的制备方法,包含该树突状细胞的用于预防或治疗癌症或者抑制癌症转移的药物组合物及试剂盒(kit) |
| WO2011109833A2 (en) | 2010-03-05 | 2011-09-09 | President And Fellows Of Harvard College | Induced dendritic cell compositions and uses thereof |
| CN104379730B (zh) * | 2012-05-31 | 2016-12-14 | Jw可瑞基因株式会社 | 使树突细胞成熟的组合物以及用其制备抗原特异性树突细胞的方法 |
| US20140037606A1 (en) | 2012-08-06 | 2014-02-06 | Eyal Amiel | Cell-based, anti-cancer vaccines |
| ES2973283T3 (es) | 2016-08-01 | 2024-06-19 | Tenacia Biotechnology Hong Kong Co Ltd | Moduladores de receptores de NMDA espirolactámicos y usos de los mismos |
-
2014
- 2014-08-01 KR KR1020140099281A patent/KR101518972B1/ko active Active
-
2015
- 2015-07-28 CN CN201580046565.6A patent/CN106604989B/zh active Active
- 2015-07-28 JP JP2017526028A patent/JP6602377B2/ja active Active
- 2015-07-28 WO PCT/KR2015/007892 patent/WO2016018053A1/ko not_active Ceased
- 2015-07-28 DK DK15828295.4T patent/DK3176258T3/da active
- 2015-07-28 US US15/327,933 patent/US10478479B2/en active Active
- 2015-07-28 EP EP15828295.4A patent/EP3176258B1/en active Active
- 2015-07-28 ES ES15828295T patent/ES2796299T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20170196955A1 (en) | 2017-07-13 |
| EP3176258A1 (en) | 2017-06-07 |
| JP2017530723A (ja) | 2017-10-19 |
| CN106604989B (zh) | 2020-10-16 |
| US10478479B2 (en) | 2019-11-19 |
| EP3176258A4 (en) | 2018-03-28 |
| KR101518972B1 (ko) | 2015-05-18 |
| CN106604989A (zh) | 2017-04-26 |
| JP6602377B2 (ja) | 2019-11-06 |
| WO2016018053A1 (ko) | 2016-02-04 |
| ES2796299T3 (es) | 2020-11-26 |
| EP3176258B1 (en) | 2020-05-13 |
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