DK3164195T3 - Glutaminaseinhibitorterapi - Google Patents
Glutaminaseinhibitorterapi Download PDFInfo
- Publication number
- DK3164195T3 DK3164195T3 DK15814655.5T DK15814655T DK3164195T3 DK 3164195 T3 DK3164195 T3 DK 3164195T3 DK 15814655 T DK15814655 T DK 15814655T DK 3164195 T3 DK3164195 T3 DK 3164195T3
- Authority
- DK
- Denmark
- Prior art keywords
- inhibitor therapy
- glutamine inhibitor
- glutamine
- therapy
- inhibitor
- Prior art date
Links
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462020524P | 2014-07-03 | 2014-07-03 | |
| US201462020731P | 2014-07-03 | 2014-07-03 | |
| US201462020539P | 2014-07-03 | 2014-07-03 | |
| US201462020519P | 2014-07-03 | 2014-07-03 | |
| US201562187160P | 2015-06-30 | 2015-06-30 | |
| US14/791,186 US9809588B2 (en) | 2014-07-03 | 2015-07-02 | GLS1 inhibitors for treating disease |
| US14/791,206 US20160002248A1 (en) | 2014-07-03 | 2015-07-02 | Gls1 inhibitors for treating disease |
| PCT/US2015/039153 WO2016004418A1 (en) | 2014-07-03 | 2015-07-03 | Glutaminase inhibitor therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3164195T3 true DK3164195T3 (da) | 2022-07-11 |
Family
ID=58452269
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15814655.5T DK3164195T3 (da) | 2014-07-03 | 2015-07-03 | Glutaminaseinhibitorterapi |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP3164195B1 (da) |
| DK (1) | DK3164195T3 (da) |
| ES (1) | ES2921989T3 (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115594683B (zh) * | 2021-11-02 | 2023-06-16 | 杭州禹胜医药科技有限公司 | 谷氨酰胺酶gls1抑制剂及其制备方法与应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2686933A1 (en) * | 2007-04-06 | 2008-10-16 | The Johns Hopkins University | Methods and compositions for the treatment of cancer |
| WO2011143160A2 (en) * | 2010-05-10 | 2011-11-17 | The Johns Hopkins University | Metabolic inhibitor against tumors having an idh mutation |
| JP6275153B2 (ja) * | 2012-11-16 | 2018-02-07 | キャリセラ バイオサイエンシーズ， インコーポレイテッド | ヘテロ環式グルタミナーゼ阻害剤 |
-
2015
- 2015-07-03 ES ES15814655T patent/ES2921989T3/es active Active
- 2015-07-03 EP EP15814655.5A patent/EP3164195B1/en active Active
- 2015-07-03 DK DK15814655.5T patent/DK3164195T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3164195B1 (en) | 2022-06-15 |
| ES2921989T3 (es) | 2022-09-05 |
| EP3164195A4 (en) | 2018-01-17 |
| EP3164195A1 (en) | 2017-05-10 |
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