DK3085794T3 - Fremgangsmåde til detektion af et oligonukleotid - Google Patents
Fremgangsmåde til detektion af et oligonukleotid Download PDFInfo
- Publication number
- DK3085794T3 DK3085794T3 DK16169301.5T DK16169301T DK3085794T3 DK 3085794 T3 DK3085794 T3 DK 3085794T3 DK 16169301 T DK16169301 T DK 16169301T DK 3085794 T3 DK3085794 T3 DK 3085794T3
- Authority
- DK
- Denmark
- Prior art keywords
- oligonucleotide
- detecting
- Prior art date
Links
- 108091034117 Oligonucleotide Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08166721 | 2008-10-15 | ||
| EP09783760.3A EP2337860B1 (en) | 2008-10-15 | 2009-10-06 | Oligonucleotide detection method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3085794T3 true DK3085794T3 (da) | 2020-06-08 |
Family
ID=41319548
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16169301.5T DK3085794T3 (da) | 2008-10-15 | 2009-10-06 | Fremgangsmåde til detektion af et oligonukleotid |
| DK09783760.3T DK2337860T3 (da) | 2008-10-15 | 2009-10-06 | Fremgangsmåde til detektion af oligonukleotider |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK09783760.3T DK2337860T3 (da) | 2008-10-15 | 2009-10-06 | Fremgangsmåde til detektion af oligonukleotider |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10711298B2 (da) |
| EP (2) | EP2337860B1 (da) |
| JP (1) | JP2012505644A (da) |
| CN (1) | CN102186993A (da) |
| CA (1) | CA2739672C (da) |
| DK (2) | DK3085794T3 (da) |
| ES (2) | ES2588253T3 (da) |
| WO (1) | WO2010043512A1 (da) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2582235C2 (ru) | 2010-12-29 | 2016-04-20 | Ф.Хоффманн-Ля Рош Аг | Низкомолекулярные конъюгаты для внутриклеточной доставки нуклеиновых кислот |
| CN104470606B (zh) * | 2012-05-31 | 2017-03-22 | 新加坡科技研究局 | 用带负电荷颗粒对多核苷酸的色谱纯化 |
| CN104342493B (zh) * | 2014-10-13 | 2016-12-07 | 浙江省检验检疫科学技术研究院 | 单核细胞增多性李斯特菌的肽核酸分子信标标记和荧光扫描检测方法 |
| CA2976427C (en) * | 2015-03-02 | 2021-08-03 | Axolabs Gmbh | Simultaneous detection of oligonucleotides, a kit and a use related thereto |
| WO2016161388A1 (en) | 2015-04-03 | 2016-10-06 | University Of Massachusetts | Fully stabilized asymmetric sirna |
| WO2017030973A1 (en) | 2015-08-14 | 2017-02-23 | University Of Massachusetts | Bioactive conjugates for oligonucleotide delivery |
| WO2017068087A1 (en) | 2015-10-22 | 2017-04-27 | Roche Innovation Center Copenhagen A/S | Oligonucleotide detection method |
| JP7749201B6 (ja) | 2016-01-31 | 2025-10-21 | ユニバーシティー オブ マサチューセッツ | 分岐オリゴヌクレオチド |
| CA3033368A1 (en) | 2016-08-12 | 2018-02-15 | University Of Massachusetts | Conjugated oligonucleotides |
| CN110799647A (zh) | 2017-06-23 | 2020-02-14 | 马萨诸塞大学 | 双尾自递送sirna及相关的方法 |
| US20210207123A1 (en) | 2018-05-30 | 2021-07-08 | Axolabs Gmbh | Method for detecting oligonucleotide conjugates |
| US11279930B2 (en) | 2018-08-23 | 2022-03-22 | University Of Massachusetts | O-methyl rich fully stabilized oligonucleotides |
| CN114502730A (zh) | 2019-08-09 | 2022-05-13 | 马萨诸塞大学 | 经化学修饰的靶向snp的寡核苷酸 |
| US12365894B2 (en) | 2019-09-16 | 2025-07-22 | University Of Massachusetts | Branched lipid conjugates of siRNA for specific tissue delivery |
| CN110564830B (zh) * | 2019-10-18 | 2023-07-18 | 湖南工业大学 | 一种基于内标法和定量分析模型的荧光定量pcr方法 |
| CN113943778A (zh) * | 2020-07-17 | 2022-01-18 | 通用电气医疗集团股份有限公司 | 用于核酸检测的分子探针及其制备方法和用途 |
| EP4359539A4 (en) | 2021-06-23 | 2025-05-14 | University Of Massachusetts | ANTI-FLT1 OLIGONUCLEOTIDE COMPOUNDS OPTIMIZED FOR THE TREATMENT OF PREECLAMPSIA AND OTHER ANGIOGENIC DISORDERS |
| WO2024117156A1 (ja) * | 2022-11-30 | 2024-06-06 | 積水メディカル株式会社 | 核酸測定方法 |
| CN116297945A (zh) * | 2023-03-08 | 2023-06-23 | 杭州诺泰诺和生物医药科技有限公司 | 一种寡核苷酸强阴离子交换液相色谱分析方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2033718A1 (en) * | 1990-01-19 | 1991-07-20 | Ronald M. Atlas | Process for detection of water-borne microbial pathogens and indicators of human fecal contamination in water samples and kits therefor |
| US5866429A (en) * | 1991-04-03 | 1999-02-02 | Bloch; Will | Precision and accuracy of anion-exchange separation of nucleic acids |
| US5539082A (en) * | 1993-04-26 | 1996-07-23 | Nielsen; Peter E. | Peptide nucleic acids |
| DK51092D0 (da) | 1991-05-24 | 1992-04-15 | Ole Buchardt | Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf |
| US6045995A (en) | 1994-08-24 | 2000-04-04 | Isis Pharmaceuticals, Inc. | Capillary electrophoretic detection of nucleic acids |
| US6444650B1 (en) * | 1996-10-01 | 2002-09-03 | Geron Corporation | Antisense compositions for detecting and inhibiting telomerase reverse transcriptase |
| US6031098A (en) * | 1997-08-11 | 2000-02-29 | California Institute Of Technology | Detection and treatment of duplex polynucleotide damage |
| US6326479B1 (en) * | 1998-01-27 | 2001-12-04 | Boston Probes, Inc. | Synthetic polymers and methods, kits or compositions for modulating the solubility of same |
| US6403313B1 (en) * | 1999-12-21 | 2002-06-11 | Ingeneus Corporation | Fluorescent intensity assay for duplex and triplex nucleic acid hybridization solution utilizing fluorescent intercalators |
| WO2002010186A1 (en) * | 2000-07-27 | 2002-02-07 | California Institute Of Technology | A rapid, quantitative method for the mass spectrometric analysis of nucleic acids for gene expression and genotyping |
| US20030199442A1 (en) * | 2001-10-09 | 2003-10-23 | Alsobrook John P. | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| WO2004087950A2 (en) * | 2003-04-04 | 2004-10-14 | Roche Diagnostics Gmbh | Improved system for multi color real time pcr |
| CN1882603A (zh) * | 2003-11-25 | 2006-12-20 | 阿哥斯医疗公司 | mRNA转染的抗原呈递细胞 |
| AU2005222902B2 (en) * | 2004-03-12 | 2010-06-10 | Alnylam Pharmaceuticals, Inc. | iRNA agents targeting VEGF |
| EP1766089A1 (en) * | 2004-06-30 | 2007-03-28 | Applera Corporation | Analog probe complexes |
| US7572640B2 (en) * | 2004-09-28 | 2009-08-11 | Singulex, Inc. | Method for highly sensitive detection of single protein molecules labeled with fluorescent moieties |
| WO2007127935A1 (en) * | 2006-04-27 | 2007-11-08 | J. David Gladstone Institutes | Dephosphorylation of hdac7 by myosin phosphatase |
| EP1914317A1 (en) | 2006-10-21 | 2008-04-23 | Biolytix AG | A method for qualitative and quantitative detection of short nucleic acid sequences of about 8 to 50 nucleotides in length |
| WO2015065595A1 (en) * | 2013-10-30 | 2015-05-07 | Trustees Of Dartmouth College | Method for selectively inhibiting acat1 in the treatment of obesity, metabolic syndrome, and atherosclerosis |
| US20180245077A1 (en) * | 2015-03-20 | 2018-08-30 | Protiva Biotherapeutics, Inc. | Compositions and methods for treating hypertriglyceridemia |
| US10422003B2 (en) * | 2015-03-23 | 2019-09-24 | The Regents Of The University Of California | Methods for detection of RNase activity |
-
2009
- 2009-10-06 US US13/124,411 patent/US10711298B2/en active Active
- 2009-10-06 CN CN2009801410091A patent/CN102186993A/zh active Pending
- 2009-10-06 DK DK16169301.5T patent/DK3085794T3/da active
- 2009-10-06 DK DK09783760.3T patent/DK2337860T3/da active
- 2009-10-06 WO PCT/EP2009/062926 patent/WO2010043512A1/en not_active Ceased
- 2009-10-06 CA CA2739672A patent/CA2739672C/en active Active
- 2009-10-06 EP EP09783760.3A patent/EP2337860B1/en active Active
- 2009-10-06 JP JP2011531439A patent/JP2012505644A/ja active Pending
- 2009-10-06 EP EP16169301.5A patent/EP3085794B1/en active Active
- 2009-10-06 ES ES09783760.3T patent/ES2588253T3/es active Active
- 2009-10-06 ES ES16169301T patent/ES2794401T3/es active Active
-
2018
- 2018-05-07 US US15/972,331 patent/US20180312909A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2739672A1 (en) | 2010-04-22 |
| US20180312909A1 (en) | 2018-11-01 |
| EP2337860A1 (en) | 2011-06-29 |
| US20110201006A1 (en) | 2011-08-18 |
| CA2739672C (en) | 2017-03-28 |
| EP2337860B1 (en) | 2016-05-25 |
| JP2012505644A (ja) | 2012-03-08 |
| US10711298B2 (en) | 2020-07-14 |
| CN102186993A (zh) | 2011-09-14 |
| EP3085794A1 (en) | 2016-10-26 |
| EP3085794B1 (en) | 2020-03-18 |
| ES2588253T3 (es) | 2016-10-31 |
| DK2337860T3 (da) | 2016-08-29 |
| WO2010043512A1 (en) | 2010-04-22 |
| ES2794401T3 (es) | 2020-11-18 |
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