DK3083997T3 - Diagnostiske, prognostiske og terapeutiske anvendelser af lange ikke-kodende rna¿er til hjertelidelser og regenerativ lægemiddel - Google Patents
Diagnostiske, prognostiske og terapeutiske anvendelser af lange ikke-kodende rna¿er til hjertelidelser og regenerativ lægemiddel Download PDFInfo
- Publication number
- DK3083997T3 DK3083997T3 DK14828456.5T DK14828456T DK3083997T3 DK 3083997 T3 DK3083997 T3 DK 3083997T3 DK 14828456 T DK14828456 T DK 14828456T DK 3083997 T3 DK3083997 T3 DK 3083997T3
- Authority
- DK
- Denmark
- Prior art keywords
- rnaes
- prognostic
- diagnostic
- coding
- therapeutic uses
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 208000019622 heart disease Diseases 0.000 title 1
- 230000001172 regenerating effect Effects 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361964591P | 2013-12-20 | 2013-12-20 | |
| PCT/EP2014/078868 WO2015092020A2 (en) | 2013-12-20 | 2014-12-19 | Diagnostic, prognostic and therapeutic uses of long noncoding rnas for heart disease and regenerative medicine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3083997T3 true DK3083997T3 (da) | 2020-10-19 |
Family
ID=52394217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14828456.5T DK3083997T3 (da) | 2013-12-20 | 2014-12-19 | Diagnostiske, prognostiske og terapeutiske anvendelser af lange ikke-kodende rna¿er til hjertelidelser og regenerativ lægemiddel |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11193171B2 (da) |
| EP (2) | EP3083997B1 (da) |
| DK (1) | DK3083997T3 (da) |
| ES (1) | ES2837437T3 (da) |
| HU (1) | HUE051159T2 (da) |
| IL (3) | IL285107B2 (da) |
| PL (1) | PL3083997T3 (da) |
| PT (1) | PT3083997T (da) |
| SI (1) | SI3083997T1 (da) |
| WO (1) | WO2015092020A2 (da) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11660317B2 (en) | 2004-11-08 | 2023-05-30 | The Johns Hopkins University | Compositions comprising cardiosphere-derived cells for use in cell therapy |
| EP2882445B1 (en) | 2012-08-13 | 2019-04-24 | Cedars-Sinai Medical Center | Exosomes and micro-ribonucleic acids for tissue regeneration |
| US11357799B2 (en) | 2014-10-03 | 2022-06-14 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy |
| WO2017123662A1 (en) | 2016-01-11 | 2017-07-20 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction |
| CN105802969A (zh) * | 2016-05-10 | 2016-07-27 | 新疆医科大学第附属医院 | lncRNA ENST00000581794.1及制剂或诊断剂或药物或试剂盒和应用 |
| WO2017210652A1 (en) | 2016-06-03 | 2017-12-07 | Cedars-Sinai Medical Center | Cdc-derived exosomes for treatment of ventricular tachyarrythmias |
| CN107460234B (zh) * | 2016-06-06 | 2020-06-16 | 王辉云 | 血清48-lncRNA作为肝脏慢性疾病诊断标记物的应用 |
| WO2018007525A2 (en) * | 2016-07-07 | 2018-01-11 | Siemens Healthcare Gmbh | Epigenome-wide association study identifies cardiac developmental gene patterning and a novel class of biomarkers for heart failure |
| US11541078B2 (en) | 2016-09-20 | 2023-01-03 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders |
| US20190127795A1 (en) * | 2017-04-13 | 2019-05-02 | Tiffany Wu | Method for prognosing and reducing cardiovascular disease in patients with kidney diseases |
| US20180299428A1 (en) * | 2017-04-13 | 2018-10-18 | Tiffany Wu | Method for prognosing adverse cardiovascular outcome in patients with coronary artery diseases |
| CA3059910A1 (en) | 2017-04-19 | 2018-10-25 | Cedars-Sinai Medical Center | Methods and compositions for treating skeletal muscular dystrophy |
| US11667974B2 (en) | 2017-06-12 | 2023-06-06 | Firalis Sa | Diagnostic, prognostic and therapeutic uses of long noncoding RNAs for pathologies and toxicities inducing heart disorders |
| EP3641833B1 (en) * | 2017-06-19 | 2025-07-23 | Université de Lausanne | Compositions for controlling cardiac fibrosis and remodeling |
| US11708600B2 (en) * | 2017-10-05 | 2023-07-25 | Decode Health, Inc. | Long non-coding RNA gene expression signatures in disease diagnosis |
| US11660355B2 (en) | 2017-12-20 | 2023-05-30 | Cedars-Sinai Medical Center | Engineered extracellular vesicles for enhanced tissue delivery |
| CN107948321B (zh) * | 2017-12-29 | 2021-10-12 | 威马智慧出行科技（上海）有限公司 | 车辆的远程授权方法及系统 |
| WO2019152549A1 (en) | 2018-02-05 | 2019-08-08 | Cedars-Sinai Medical Center | Methods for therapeutic use of exosomes and y-rnas |
| CN108148908B (zh) * | 2018-03-16 | 2020-05-12 | 中国人民解放军沈阳军区总医院 | 动脉粥样硬化性肾动脉狭窄诊断分子标记物的应用 |
| CN110396542A (zh) * | 2019-05-20 | 2019-11-01 | 徐州市疾病预防控制中心(徐州市健康教育所) | 一种LncRNA标记物及其在糖尿病中的应用 |
| EP4153743A4 (en) * | 2020-05-19 | 2025-09-24 | Cedars Sinai Medical Center | EXOSOME-DERIVED PIWI-INTERACTING RNA AND METHODS OF USE THEREOF |
| CN112176053B (zh) * | 2020-10-12 | 2021-06-25 | 山东大学齐鲁医院(青岛) | 一种急性重症病毒性心肌炎基因标志物 |
| CN113388673B (zh) * | 2021-04-28 | 2022-09-20 | 广东省人民医院 | 长非编码rna carmen的应用 |
| KR102643120B1 (ko) * | 2021-11-12 | 2024-03-05 | 재단법인 아산사회복지재단 | 대동맥판막 협착증의 진단을 위한 미토콘드리아 바이오마커 및 미토콘드리아 활성화제를 포함하는 대동맥판막 협착증의 예방 또는 치료용 약학적 조성물 |
| WO2024003205A1 (en) * | 2022-06-30 | 2024-01-04 | Medizinische Hochschule Hannover | Long non-coding rnas as target for treating fibrosis and cancer |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| GB2236186B (en) | 1989-08-22 | 1994-01-05 | Finnigan Mat Gmbh | Process and device for laser desorption of analyte molecular ions, especially of biomolecules |
| US5545522A (en) | 1989-09-22 | 1996-08-13 | Van Gelder; Russell N. | Process for amplifying a target polynucleotide sequence using a single primer-promoter complex |
| US5045694A (en) | 1989-09-27 | 1991-09-03 | The Rockefeller University | Instrument and method for the laser desorption of ions in mass spectrometry |
| ES2201077T3 (es) | 1993-05-28 | 2004-03-16 | Baylor College Of Medicine | Metodo y espectrometro de masas para la desorcion e ionizacion de analitos. |
| US5578832A (en) | 1994-09-02 | 1996-11-26 | Affymetrix, Inc. | Method and apparatus for imaging a sample on a device |
| US5539083A (en) | 1994-02-23 | 1996-07-23 | Isis Pharmaceuticals, Inc. | Peptide nucleic acid combinatorial libraries and improved methods of synthesis |
| US5556752A (en) | 1994-10-24 | 1996-09-17 | Affymetrix, Inc. | Surface-bound, unimolecular, double-stranded DNA |
| US6028189A (en) | 1997-03-20 | 2000-02-22 | University Of Washington | Solvent for oligonucleotide synthesis and methods of use |
| NZ516848A (en) | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
| US7013221B1 (en) | 1999-07-16 | 2006-03-14 | Rosetta Inpharmatics Llc | Iterative probe design and detailed expression profiling with flexible in-situ synthesis arrays |
| ES2905579T3 (es) | 2003-07-10 | 2022-04-11 | Genomic Health Inc | Algoritmo del perfil de expresión y prueba para el pronóstico de la recaída del cáncer de mama |
| US7312035B2 (en) * | 2004-09-03 | 2007-12-25 | Affymetrix, Inc. | Methods of genetic analysis of yeast |
| CA2767231A1 (en) * | 2009-07-06 | 2011-01-13 | Alnylam Pharmaceuticals, Inc. | Cell-based bioprocessing |
| US20160319361A1 (en) * | 2013-08-28 | 2016-11-03 | Caris Life Sciences Switzerland Holdings Gmbh | Oligonucleotide probes and uses thereof |
-
2014
- 2014-12-19 HU HUE14828456A patent/HUE051159T2/hu unknown
- 2014-12-19 ES ES14828456T patent/ES2837437T3/es active Active
- 2014-12-19 EP EP14828456.5A patent/EP3083997B1/en active Active
- 2014-12-19 DK DK14828456.5T patent/DK3083997T3/da active
- 2014-12-19 US US15/105,319 patent/US11193171B2/en active Active
- 2014-12-19 WO PCT/EP2014/078868 patent/WO2015092020A2/en not_active Ceased
- 2014-12-19 EP EP20176907.2A patent/EP3825419A3/en active Pending
- 2014-12-19 PT PT148284565T patent/PT3083997T/pt unknown
- 2014-12-19 IL IL285107A patent/IL285107B2/en unknown
- 2014-12-19 PL PL14828456T patent/PL3083997T3/pl unknown
- 2014-12-19 SI SI201431696T patent/SI3083997T1/sl unknown
-
2016
- 2016-06-08 IL IL246103A patent/IL246103B/en active IP Right Grant
-
2020
- 2020-01-23 IL IL272226A patent/IL272226B/en unknown
-
2021
- 2021-10-19 US US17/505,153 patent/US20220136054A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL285107B1 (en) | 2023-10-01 |
| IL272226A (en) | 2020-03-31 |
| IL246103A0 (en) | 2016-07-31 |
| PT3083997T (pt) | 2020-11-03 |
| PL3083997T3 (pl) | 2021-04-06 |
| EP3825419A2 (en) | 2021-05-26 |
| SI3083997T1 (sl) | 2020-12-31 |
| IL272226B (en) | 2021-08-31 |
| ES2837437T3 (es) | 2021-06-30 |
| EP3083997A2 (en) | 2016-10-26 |
| US20160312283A1 (en) | 2016-10-27 |
| IL285107A (en) | 2021-08-31 |
| WO2015092020A3 (en) | 2015-09-24 |
| HUE051159T2 (hu) | 2021-03-01 |
| IL285107B2 (en) | 2024-02-01 |
| EP3825419A3 (en) | 2021-09-15 |
| IL246103B (en) | 2020-02-27 |
| US11193171B2 (en) | 2021-12-07 |
| WO2015092020A2 (en) | 2015-06-25 |
| US20220136054A1 (en) | 2022-05-05 |
| EP3083997B1 (en) | 2020-07-29 |
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