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DK3081637T3 - Fremgangsmåde til fremstilling af en ciliær marginalzonelignende struktur - Google Patents

Fremgangsmåde til fremstilling af en ciliær marginalzonelignende struktur Download PDF

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Publication number
DK3081637T3
DK3081637T3 DK14869571.1T DK14869571T DK3081637T3 DK 3081637 T3 DK3081637 T3 DK 3081637T3 DK 14869571 T DK14869571 T DK 14869571T DK 3081637 T3 DK3081637 T3 DK 3081637T3
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DK
Denmark
Prior art keywords
ciliar
preparing
procedure
similar structure
margin zone
Prior art date
Application number
DK14869571.1T
Other languages
English (en)
Inventor
Yoshiki Sasai
Atsushi Kuwahara
Original Assignee
Sumitomo Chemical Co
Riken
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Filing date
Publication date
Application filed by Sumitomo Chemical Co, Riken filed Critical Sumitomo Chemical Co
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Publication of DK3081637T3 publication Critical patent/DK3081637T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0618Cells of the nervous system
    • C12N5/0621Eye cells, e.g. cornea, iris pigmented cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • A61K9/0051Ocular inserts, ocular implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/64Animal cells
    • AHUMAN NECESSITIES
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    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/16Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea
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    • C12N2501/155Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
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DK14869571.1T 2013-12-11 2014-10-16 Fremgangsmåde til fremstilling af en ciliær marginalzonelignende struktur DK3081637T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2013255836 2013-12-11
PCT/JP2014/077602 WO2015087614A1 (ja) 2013-12-11 2014-10-16 毛様体周縁部様構造体の製造法

Publications (1)

Publication Number Publication Date
DK3081637T3 true DK3081637T3 (da) 2019-08-12

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DK14869571.1T DK3081637T3 (da) 2013-12-11 2014-10-16 Fremgangsmåde til fremstilling af en ciliær marginalzonelignende struktur

Country Status (12)

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US (2) US10233423B2 (da)
EP (2) EP3524671A1 (da)
JP (3) JP6495830B2 (da)
KR (1) KR102318706B1 (da)
CN (1) CN105960454B (da)
AU (1) AU2014362722B2 (da)
CA (1) CA2933258C (da)
DK (1) DK3081637T3 (da)
ES (1) ES2741309T3 (da)
MY (1) MY184796A (da)
SG (1) SG11201604705UA (da)
WO (1) WO2015087614A1 (da)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11241460B2 (en) 2013-03-15 2022-02-08 Astellas Institute For Regenerative Medicine Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells
DK3081637T3 (da) * 2013-12-11 2019-08-12 Sumitomo Chemical Co Fremgangsmåde til fremstilling af en ciliær marginalzonelignende struktur
SG11201605833PA (en) * 2014-01-17 2016-08-30 Sumitomo Chemical Co Method for manufacturing ciliary margin stem cells
ES2880353T3 (es) 2014-10-24 2021-11-24 Sumitomo Dainippon Pharma Co Ltd Método de producción de tejido retiniano
CN107109367B (zh) 2014-10-24 2021-08-10 大日本住友制药株式会社 神经组织的制备方法
ES2971677T3 (es) 2015-09-08 2024-06-06 Sumitomo Pharma Co Ltd Método para la producción de tejido retiniano
CA3021828A1 (en) 2016-04-22 2017-10-26 Sumitomo Dainippon Pharma Co., Ltd. Method for producing retinal tissue
JP7150281B2 (ja) 2017-07-20 2022-10-11 国立研究開発法人理化学研究所 連続的な上皮を含む網膜組織の成熟化方法
US20200277571A1 (en) * 2017-09-14 2020-09-03 Riken Method for amplifying cone photoreceptors or rod photoreceptors using dorsalization signal transmitter or ventralization signal transmitter
US12090252B2 (en) 2017-09-14 2024-09-17 Riken Method for producing retinal tissues
AU2019266276A1 (en) * 2018-05-09 2020-12-03 The Regents Of The University Of Colorado, A Body Corporate Stem cell-derived cell cultures, stem cell-derived three-dimensional tissue products, and methods of making and using the same
KR20210138639A (ko) * 2019-03-13 2021-11-19 다이니뽄 스미토모 세이야쿠 가부시키가이샤 이식용 신경 망막의 품질을 평가하는 방법 및 이식용 신경 망막 시트

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IE903130A1 (en) * 1989-09-15 1991-03-27 Regeneron Pharma Ciliary neurotrophic factor
US6045791A (en) * 1992-03-06 2000-04-04 Photogenesis, Inc. Retinal pigment epithelium transplantation
EP0986635A4 (en) 1997-01-10 2001-11-07 Life Technologies Inc SERUM SUBSTITUTE FOR EMBRYONIC STEM CELLS
US6007578A (en) * 1997-10-08 1999-12-28 Ras Holding Corp Scleral prosthesis for treatment of presbyopia and other eye disorders
US7824671B2 (en) * 2002-10-04 2010-11-02 Tissuetech, Inc. Retinal pigment epithelial cell cultures on amniotic membrane and transplantation
US20060247165A1 (en) * 2005-01-21 2006-11-02 Stupp Samuel I Methods and compositions for encapsulation of cells
US8927276B2 (en) * 2010-02-17 2015-01-06 Cellin Technologies Oue Ex vivo progenitor and stem cell expansion and differentiation for use in the treatment of disease of the nervous system
EP3514232A1 (en) * 2010-04-23 2019-07-24 University of Massachusetts Cns targeting aav vectors and methods of use thereof
US9783781B2 (en) * 2010-08-16 2017-10-10 Exostem Biotec Ltd. Methods of generating oligodendrocytes and cell populations comprising same
JP5985207B2 (ja) 2011-11-25 2016-09-06 住友化学株式会社 網膜色素上皮細胞の製造方法
JP5985209B2 (ja) 2011-11-25 2016-09-06 住友化学株式会社 眼杯様構造体の製造方法
CN113817679A (zh) 2011-11-25 2021-12-21 住友化学株式会社 制备视网膜组织和视网膜相关细胞的方法
JP6067232B2 (ja) 2011-11-25 2017-01-25 住友化学株式会社 網膜層特異的神経細胞を製造する方法
JP5985208B2 (ja) 2011-11-25 2016-09-06 住友化学株式会社 網膜組織の製造方法
JP2013201943A (ja) 2012-03-28 2013-10-07 Sumitomo Chemical Co Ltd 成熟肝細胞の製造方法
JP6089430B2 (ja) 2012-03-30 2017-03-08 セイコーエプソン株式会社 軟磁性粉末、圧粉磁心および磁性素子
JP6393614B2 (ja) 2012-06-08 2018-09-19 住友化学株式会社 毛様体周縁部様構造体の製造方法
DK3081637T3 (da) * 2013-12-11 2019-08-12 Sumitomo Chemical Co Fremgangsmåde til fremstilling af en ciliær marginalzonelignende struktur

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Publication number Publication date
CA2933258A1 (en) 2015-06-18
AU2014362722B2 (en) 2021-06-10
JP6495830B2 (ja) 2019-04-03
EP3081637A1 (en) 2016-10-19
KR102318706B1 (ko) 2021-10-28
CA2933258C (en) 2023-05-23
JP6991517B2 (ja) 2022-02-15
AU2014362722A1 (en) 2016-07-28
JPWO2015087614A1 (ja) 2017-03-16
SG11201604705UA (en) 2016-07-28
WO2015087614A1 (ja) 2015-06-18
JP2021192634A (ja) 2021-12-23
US20190169570A1 (en) 2019-06-06
US10233423B2 (en) 2019-03-19
EP3081637A4 (en) 2017-07-05
CN105960454A (zh) 2016-09-21
EP3524671A1 (en) 2019-08-14
EP3081637B1 (en) 2019-05-08
KR20160097303A (ko) 2016-08-17
MY184796A (en) 2021-04-22
ES2741309T3 (es) 2020-02-10
US20160376554A1 (en) 2016-12-29
US11111476B2 (en) 2021-09-07
JP2019115351A (ja) 2019-07-18
CN105960454B (zh) 2020-10-30

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