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DK3049073T3 - Sammensætninger og fremgangsmåder til destabilisering, ændring og dispergering af biofilm - Google Patents

Sammensætninger og fremgangsmåder til destabilisering, ændring og dispergering af biofilm Download PDF

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Publication number
DK3049073T3
DK3049073T3 DK14847319.2T DK14847319T DK3049073T3 DK 3049073 T3 DK3049073 T3 DK 3049073T3 DK 14847319 T DK14847319 T DK 14847319T DK 3049073 T3 DK3049073 T3 DK 3049073T3
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DK
Denmark
Prior art keywords
disperger
destabilization
biofilm
procedures
compositions
Prior art date
Application number
DK14847319.2T
Other languages
English (en)
Inventor
Alexander Rickard
Nick Jakubovics
Derek S Samarian
Ethan Kolderman
Original Assignee
Univ Michigan Regents
Univ Newcastle
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52744423&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3049073(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Michigan Regents, Univ Newcastle filed Critical Univ Michigan Regents
Application granted granted Critical
Publication of DK3049073T3 publication Critical patent/DK3049073T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4425Pyridinium derivatives, e.g. pralidoxime, pyridostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/14Streptococcus; Staphylococcus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806Determination of free amino acids
    • G01N33/6812Assays for specific amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/10Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Physiology (AREA)
DK14847319.2T 2013-09-24 2014-09-24 Sammensætninger og fremgangsmåder til destabilisering, ændring og dispergering af biofilm DK3049073T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361881762P 2013-09-24 2013-09-24
US201461972920P 2014-03-31 2014-03-31
PCT/US2014/057235 WO2015048146A1 (en) 2013-09-24 2014-09-24 Compositions and method for destabilizing, altering, and dispersing biofilms

Publications (1)

Publication Number Publication Date
DK3049073T3 true DK3049073T3 (da) 2021-02-01

Family

ID=52744423

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14847319.2T DK3049073T3 (da) 2013-09-24 2014-09-24 Sammensætninger og fremgangsmåder til destabilisering, ændring og dispergering af biofilm

Country Status (11)

Country Link
US (2) US20160235698A1 (da)
EP (3) EP3049073B1 (da)
CN (3) CN110129352A (da)
AU (6) AU2014326756B2 (da)
BR (1) BR112016006584B1 (da)
DK (1) DK3049073T3 (da)
ES (1) ES2847388T3 (da)
MX (1) MX374836B (da)
PL (1) PL3049073T3 (da)
WO (1) WO2015048146A1 (da)
ZA (1) ZA201602797B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5548121B2 (ja) 2007-05-14 2014-07-16 リサーチ ファウンデーション オブ ステイト ユニバーシティ オブ ニューヨーク バイオフィルム中の細菌細胞における生理学的分散応答の誘導
AU2014326756B2 (en) 2013-09-24 2019-08-29 The Regents Of The University Of Michigan Compositions and method for destabilizing, altering, and dispersing biofilms
US9795579B1 (en) * 2017-04-24 2017-10-24 Knoze Jr. Corporation Oral microbiota promoting method
US12194105B2 (en) * 2018-02-21 2025-01-14 The Board Of Trustees Of The Leland Stanford Junior University Composition and method for new antimicrobial agents with secondary mode of action provided by conjugation of an antimicrobial to a guanidinium-rich molecular transporter
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
US10927397B2 (en) 2018-10-16 2021-02-23 Sterilex, Llc Compositions, devices and methods for detecting biofilms
WO2020139698A1 (en) * 2018-12-26 2020-07-02 Colgate-Palmolive Company Specific co-aggregation inhibition by arginine
CN119792113A (zh) * 2018-12-26 2025-04-11 高露洁-棕榄公司 使用精氨酸降低病原性细菌
CA3123091A1 (en) * 2018-12-26 2020-07-02 Colgate-Palmolive Company Methods of shifting biofilm in the oral cavity from pathogenic to healthy biofilm
CN113543763B (zh) * 2019-03-29 2023-12-22 高露洁-棕榄公司 口腔护理产品
CN110583697B (zh) * 2019-09-20 2021-04-06 浙江工商大学 去除铜绿假单胞菌生物膜用的高效化学生物制剂及其应用
US12332160B2 (en) 2019-11-08 2025-06-17 Colgate-Palmolive Company Apparatus, system, and method for testing biological samples
WO2021092613A1 (en) * 2019-11-08 2021-05-14 Colgate-Palmolive Company Methods of modifying biofilm
CN111299267B (zh) * 2020-02-12 2021-10-22 上海交通大学 一种基于群感效应的供水管网生物膜控制方法及其应用
WO2023114550A2 (en) * 2021-12-19 2023-06-22 The Trustees Of Columbia University In The City Of New York Engineering bacteria swarm patterns for spatiotemporal information encoding
CN119112857A (zh) * 2024-09-18 2024-12-13 中国科学技术大学 抑制金葡菌生物被膜形成的组合物及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0065884B1 (en) 1981-05-27 1986-08-20 Unitika Ltd. Urethral catheter capable of preventing urinary tract infection and process for producing the same
EP1159951A1 (en) * 2000-06-02 2001-12-05 Societe Des Produits Nestle S.A. Use of exogenous lactic bacteria strain against Actinomyces naeslundii-related diseases
WO2000066616A1 (en) * 1999-05-03 2000-11-09 Advanced Research & Technology Institute, Inc. METHODS AND COMPOSITIONS FOR CONTROLLING DENTAL CARIES, AND RECOMBINANT SmaA POLYPEPTIDES USEFUL FOR SAME
AU2001286741A1 (en) * 2000-08-25 2002-03-04 Trustees Of Tufts College Methods and compositions for potentiating antibiotic action against persistent/tolerant pathogenic microorganisms
US20090202450A1 (en) * 2008-02-08 2009-08-13 Colgate-Palmolive Company Oral care product and methods of use and manufacture thereof
US20100021942A1 (en) * 2008-07-25 2010-01-28 Paul Freemont Cell-free expression system for the detection of bacterial biofilms
CN102264636A (zh) * 2008-12-22 2011-11-30 微纯公司 用于减少牙齿的脱矿质的组合物和方法
CN102946841A (zh) * 2010-06-23 2013-02-27 高露洁-棕榄公司 治疗用口腔组合物
WO2012057739A1 (en) 2010-10-27 2012-05-03 Colgate-Palmolive Company Oral care composition comprising arginine and calcium carbonate
US9717929B2 (en) * 2010-12-07 2017-08-01 Colgate-Palmolive Company Dentifrice compositions containing calcium silicate and a basic amino acid
JP6038167B2 (ja) * 2011-10-31 2016-12-07 ケーン バイオテク インコーポレーテッド 口腔疾患を予防及び治療する組成物及び方法
RU2014128847A (ru) * 2011-12-15 2016-02-10 Колгейт-Палмолив Компани Композиции для гигиены полости рта
AU2014326756B2 (en) 2013-09-24 2019-08-29 The Regents Of The University Of Michigan Compositions and method for destabilizing, altering, and dispersing biofilms

Also Published As

Publication number Publication date
CN110129352A (zh) 2019-08-16
AU2019271937B2 (en) 2021-01-28
US20160304886A1 (en) 2016-10-20
ZA201602797B (en) 2018-12-19
AU2022271381B2 (en) 2024-08-15
AU2022271381A1 (en) 2022-12-15
AU2016202002A1 (en) 2016-04-21
US10570401B2 (en) 2020-02-25
EP3150715A1 (en) 2017-04-05
EP3831374A1 (en) 2021-06-09
AU2021202650A1 (en) 2021-05-27
EP3049073A4 (en) 2017-03-15
EP3049073A1 (en) 2016-08-03
PL3049073T3 (pl) 2021-10-25
US20160235698A1 (en) 2016-08-18
AU2024264692A1 (en) 2024-12-05
AU2021202650B2 (en) 2022-09-08
WO2015048146A1 (en) 2015-04-02
MX2016003791A (es) 2017-01-20
AU2014326756B2 (en) 2019-08-29
EP3150715B1 (en) 2018-11-14
AU2016202002B2 (en) 2017-10-12
CN115177607A (zh) 2022-10-14
AU2014326756A1 (en) 2016-04-07
EP3049073B1 (en) 2020-11-04
AU2019271937A1 (en) 2019-12-19
ES2847388T3 (es) 2021-08-03
BR112016006584A2 (pt) 2017-08-01
CN106029062A (zh) 2016-10-12
BR112016006584B1 (pt) 2022-11-29
MX374836B (es) 2025-03-06

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