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DK2991600T3 - : mikrolukninger og relaterede fremgangsmåder til hudbehandling - Google Patents

: mikrolukninger og relaterede fremgangsmåder til hudbehandling Download PDF

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Publication number
DK2991600T3
DK2991600T3 DK14791060.8T DK14791060T DK2991600T3 DK 2991600 T3 DK2991600 T3 DK 2991600T3 DK 14791060 T DK14791060 T DK 14791060T DK 2991600 T3 DK2991600 T3 DK 2991600T3
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DK
Denmark
Prior art keywords
skin
microclosure
tissue
sealant
less
Prior art date
Application number
DK14791060.8T
Other languages
English (en)
Inventor
Douglas Levinson
David Stone
Alec Ginggen
Original Assignee
Cytrellis Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytrellis Biosystems Inc filed Critical Cytrellis Biosystems Inc
Application granted granted Critical
Publication of DK2991600T3 publication Critical patent/DK2991600T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/064—Surgical staples, i.e. penetrating the tissue
    • A61B17/0644—Surgical staples, i.e. penetrating the tissue penetrating the tissue, deformable to closed position
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/00491—Surgical glue applicators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/068—Surgical staplers, e.g. containing multiple staples or clamps
    • A61B17/0682—Surgical staplers, e.g. containing multiple staples or clamps for applying U-shaped staples or clamps, e.g. without a forming anvil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/076—Surgical instruments, devices or methods for removing surgical staples or wound clamps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/08—Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
    • A61B17/083—Clips, e.g. resilient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1402—Probes for open surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/00051—Accessories for dressings
    • A61F13/00063—Accessories for dressings comprising medicaments or additives, e.g. odor control, PH control, debriding, antimicrobic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/00051—Accessories for dressings
    • A61F13/00085—Accessories for dressings having means for facilitating the application on the skin, e.g. single hand handling facilities
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
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    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive bandages or dressings
    • A61F13/023—Adhesive bandages or dressings wound covering film layers without a fluid retention layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F15/00—Auxiliary appliances for wound dressings; Dispensing containers for dressings or bandages
    • A61F15/005—Bandage applicators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/64—Use of materials characterised by their function or physical properties specially adapted to be resorbable inside the body
    • A—HUMAN NECESSITIES
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    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/32—Surgical cutting instruments
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    • A61B17/32—Surgical cutting instruments
    • A61B17/3205—Excision instruments
    • A61B17/32053—Punch like cutting instruments, e.g. using a cylindrical or oval knife
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/32—Surgical cutting instruments
    • A61B17/322—Skin grafting apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00004—(bio)absorbable, (bio)resorbable or resorptive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/00491—Surgical glue applicators
    • A61B2017/00504—Tissue welding
    • A61B2017/00508—Tissue welding using laser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00747—Dermatology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
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    • A61B2017/00831—Material properties
    • A61B2017/00862—Material properties elastic or resilient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
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    • A61B2017/00867—Material properties shape memory effect
    • A61B2017/00871—Material properties shape memory effect polymeric
    • A—HUMAN NECESSITIES
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61B17/00—Surgical instruments, devices or methods
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    • A61B2017/00946—Material properties malleable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
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    • A—HUMAN NECESSITIES
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    • A61B2017/0641—Surgical staples, i.e. penetrating the tissue having at least three legs as part of one single body
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    • A61B2017/0645—Surgical staples, i.e. penetrating the tissue being elastically deformed for insertion
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/32—Surgical cutting instruments
    • A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00452—Skin
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    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
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    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1405—Electrodes having a specific shape
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00365—Plasters use
    • A61F2013/0037—Plasters use for cosmesis
    • A—HUMAN NECESSITIES
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    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
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    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00902—Plasters containing means
    • A61F2013/00936—Plasters containing means metal

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Otolaryngology (AREA)
  • Plasma & Fusion (AREA)
  • Physics & Mathematics (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Rheumatology (AREA)

Claims (14)

1. Hudbehandlingsindretning omfattende en applikator omfattende (a) en hul udkerningsnål til at danne en flerhed af mikrosår i huden, hver med en arealstørrelse mindre end 4 mm2 og/eller en volumetrisk størrelse mindre end 6 mm3, og (b) en dispenser til at dispensere en volumen afen mikrolukning til mikrosårene, der er mindre end eller lig med 3 mm3, hvor mikrolukningen er eller omfatter en tætningsmiddel, hvor nævnte tætningsmiddel er resorberbart eller ikke-resorberbart.
2. Hudbehandlingsindretningen ifølge krav 1 yderligere omfattende en stift, fortrinsvis en centreringsstift, inden i lumen af nålen.
3. Hudbehandlingsindretningen ifølge krav 1, hvor mikrolukningen opretholder en første trykkraft når anvendt på nævnte mikrosår, hvor den første trykkraft inkluderer et tryk i en eller flere retninger og/eller en ekspansion i en eller flere retninger, som sammenlignet med før anvendelsen på mikrosårene, hvor trykket eller ekspansionen er en øgning eller mindskelse på mindst 0,5 % eller fra 0,5 % til 50 %, i x-aksen, y-aksen, og/eller z-aksen af mikrolukningen, som sammenlignet med før anvendelsen på mikrosårene.
4. Hudbehandlingsindretningen ifølge kravene 1-3, hvor mikrosårene er små snit i huden med en længde eller bredde på mindre end 1,0 mm.
5. Hudbehandlingsindretningen ifølge kravene 1-3, hvor mikrosårene er små huller i huden med en diameter eller bredde mindre end 1,0 mm og/eller en arealstørrelse mindre end 4 mm2 og/eller en volumetrisk størrelse, der er mindre end 6 mm3.
6. Hudbehandlingsindretningen ifølge kravene 1-5, hvor arealstørrelsen er mindre end eller lig med 1,0 mm2, eller mellem 0,001 mm2 og 1,0 mm2.
7. Hudbehandlingsindretningen ifølge kravene 1-6, hvor dispenseren dispenserer et array af en flerhed af særskilte portioner af mikrolukningen, hvor, efter anvendelse, fortrinsvis hver af nævnte mikrolukninger er separeret af mindst 10 pm, såsom mindst 100 pm.
8. Hudbehandlingsindretningen ifølge kravene 1-7, hvor nævnte tætningsmiddel er omfattet af et materiale valgt fra gruppen bestående af et plast, en polymer, et termisk følsomt materiale, et pH-følsomt materiale, et lys-følsomt materiale, et fugt-følsomt materiale, et solvent-følsomt eller kemisk påvirkning-følsomt materiale, et elektrisk felt-følsomt materiale, et magnetisk felt-følsomt materiale, et ustrakt materiale, et forstrakt materiale, et klæbestof, en biokompatibel matrix, et fotosensitiser, et fotokemisk middel, en syntetisk lim, et biologisk tætningsmiddel, et bionedbrydeligt klæbestof, en vævslim, en blanding af riboflavin-5-phosphat og fibrinogen, et fibrin-baseret tætningsmiddel, et albuminbaseret tætningsmiddel, eller et stivelses-baseret tætningsmiddel, eller kombinationer deraf.
9. Hudbehandlingsindretningen ifølge kravene 1-8, hvor mikrolukningen omfatter en hudpigmentering-modificerende forbindelse, hvor fortrinsvis nævnte hudpigmentering-modificerende forbindelse er et blegemiddel eller lysningsmiddel, såsom hydroquinon.
10. Hudbehandlingsindretningen ifølge kravene 1-9, hvor (i) dispenseren udøver en anden trykkraft før, under eller efter aflejringen af tætningsmidlet, eller (ii) indretningen yderligere omfatter et apparat til påføring af en anden trykkraft i et hudområde, hvor apparatet er en koaksial holder.
11. Kit omfattende indretningen ifølge et hvilket som helst af kravene 1-10, hvor nævnte kit eventuelt omfatter en renseserviet, en antibiotisk salve, en makrosårforbinding, og/eller instruktioner til anvendelse.
12. Kittet ifølge krav 11, yderligere omfattende en fjerner til at fjerne nævnte mikrolukning eller nævnte array, hvor nævnte fjerner er valgt fra gruppen bestående af et apparat, et kemisk middel, et biologisk middel, et polymermateriale, et slibemateriale, en makroforbinding, et adhæsivt materiale, og en mekanisk løfteindretning, hvor fortrinsvis nævnte apparat eller nævnte mekaniske løfteindretning omfatter en varmekomponent, en optisk komponent, en radiofrekvenskomponent, en mekanisk komponent, og/eller en ultralydskomponent.
13. Kittet ifølge krav 11, hvor nævnte makrosårforbinding er en justerbar forbinding.
14. Kittet ifølge krav 11, omfattende et eller flere lægemidler, hvor lægemidlet er administreret til nævnte mikrosår forud for påføringen afen mikrolukning og hvor fortrinsvis nævnte lægemiddel er administreret idet mikrosårene dannes.
DK14791060.8T 2013-05-03 2014-05-02 : mikrolukninger og relaterede fremgangsmåder til hudbehandling DK2991600T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361819190P 2013-05-03 2013-05-03
PCT/US2014/036638 WO2014179729A1 (en) 2013-05-03 2014-05-02 Microclosures and related methods for skin treatment

Publications (1)

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DK2991600T3 true DK2991600T3 (da) 2018-10-22

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US (2) US20160095592A1 (da)
EP (2) EP3456300A1 (da)
KR (2) KR102588615B1 (da)
AU (1) AU2014259645B2 (da)
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CA2910687A1 (en) 2014-11-06
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