DK2970843T3 - Fremgangsmåder til frembringelse af cellebank med høj densitet - Google Patents
Fremgangsmåder til frembringelse af cellebank med høj densitet Download PDFInfo
- Publication number
- DK2970843T3 DK2970843T3 DK14723186.4T DK14723186T DK2970843T3 DK 2970843 T3 DK2970843 T3 DK 2970843T3 DK 14723186 T DK14723186 T DK 14723186T DK 2970843 T3 DK2970843 T3 DK 2970843T3
- Authority
- DK
- Denmark
- Prior art keywords
- high density
- cell bank
- density cell
- bank procedures
- procedures
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
- C12M3/06—Tissue, human, animal or plant cell, or virus culture apparatus with filtration, ultrafiltration, inverse osmosis or dialysis means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C12M33/14—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus with filters, sieves or membranes
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/16—Physical preservation processes
- A01N1/162—Temperature processes, e.g. following predefined temperature changes over time
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/14—Mechanical aspects of preservation; Apparatus or containers therefor
- A01N1/142—Apparatus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/26—Constructional details, e.g. recesses, hinges flexible
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/16—Vibrating; Shaking; Tilting
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/10—Perfusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/16—Hollow fibers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M45/00—Means for pre-treatment of biological substances
- C12M45/22—Means for packing or storing viable microorganisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Sustainable Development (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Clinical Laboratory Science (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Water Supply & Treatment (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361793021P | 2013-03-15 | 2013-03-15 | |
| PCT/US2014/027757 WO2014143691A1 (en) | 2013-03-15 | 2014-03-14 | High-density cell banking methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2970843T3 true DK2970843T3 (da) | 2021-11-22 |
Family
ID=50687645
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14723186.4T DK2970843T3 (da) | 2013-03-15 | 2014-03-14 | Fremgangsmåder til frembringelse af cellebank med høj densitet |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US10188099B2 (da) |
| EP (2) | EP4008768A1 (da) |
| JP (1) | JP6742902B2 (da) |
| KR (2) | KR102282939B1 (da) |
| CN (2) | CN112410279A (da) |
| AR (1) | AR095354A1 (da) |
| AU (1) | AU2014228275B2 (da) |
| BR (1) | BR112015021189B1 (da) |
| CA (1) | CA2906600A1 (da) |
| CY (1) | CY1125278T1 (da) |
| DK (1) | DK2970843T3 (da) |
| ES (1) | ES2894633T3 (da) |
| HU (1) | HUE056073T2 (da) |
| IL (2) | IL241339B (da) |
| MX (1) | MX369521B (da) |
| RU (1) | RU2668796C2 (da) |
| SG (2) | SG11201506344TA (da) |
| TW (1) | TWI656839B (da) |
| WO (1) | WO2014143691A1 (da) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201506343QA (en) | 2013-02-22 | 2015-09-29 | Genzyme Corp | Microcarrier perfusion culturing methods and uses thereof |
| US10421949B2 (en) | 2013-02-22 | 2019-09-24 | Genzyme Corporation | Microcarrier perfusion culturing methods and uses thereof |
| TWI656839B (zh) | 2013-03-15 | 2019-04-21 | 健臻公司 | 高密度細胞儲存方法 |
| TWI743024B (zh) | 2014-06-06 | 2021-10-21 | 美商健臻公司 | 灌注培養方法及其用途 |
| TWI776235B (zh) | 2014-06-09 | 2022-09-01 | 美商健臻公司 | 種子罐培養法(seed train processes)及其用途 |
| EP3369316B1 (en) | 2014-08-14 | 2020-07-22 | Boehringer Ingelheim Animal Health USA Inc. | Use of a high capacity, closed, cryopreservation cell-banking system and method for thawing and dispensing banked cells |
| DK3193594T3 (da) * | 2014-09-18 | 2021-09-27 | Genzyme Corp | Fremgangsmåder til frembringelse af cellebank med ultrahøj densitet |
| KR102769649B1 (ko) | 2014-12-22 | 2025-02-19 | 젠자임 코포레이션 | 포유류 세포의 배양 방법 |
| HK1249944A1 (zh) * | 2015-06-12 | 2018-11-16 | Genea Ip Holdings Pty Limited | 用於病人和生物样本识别和跟踪的方法和系统 |
| RU2672318C1 (ru) * | 2017-09-19 | 2018-11-13 | Общество с ограниченной ответственностью "Международный Биотехнологический Центр "Генериум" | Способ получения моноклональных антител терапевтического назначения с помощью непрерывного культивирования клеток сно |
| TWI846694B (zh) | 2018-05-04 | 2024-07-01 | 美商健臻公司 | 具有過濾系統的灌注式生物反應器 |
| CN111334427B (zh) * | 2019-03-12 | 2023-05-05 | 华道(上海)生物医药有限公司 | 全封闭细胞培养系统 |
| EP3795672B1 (en) * | 2019-09-18 | 2024-11-20 | Sartorius Stedim Biotech GmbH | System and method for the generation of high cell density seed culture |
| WO2023285444A1 (en) * | 2021-07-13 | 2023-01-19 | Novo Nordisk A/S | Method for large-scale banking of human pluripotent stem cells and products derived thereof |
| US20240318114A1 (en) * | 2021-07-15 | 2024-09-26 | Just-Evotec Biologics, Inc. | Bidirectional tangential flow filtration (tff) perfusion system |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2211630A1 (en) | 1995-02-23 | 1996-08-29 | Quest International B.V. | Peptides for tissue and cell culture media |
| AUPN442295A0 (en) | 1995-07-26 | 1995-08-17 | Commonwealth Scientific And Industrial Research Organisation | Regulated autocrine growth of mammalian cells |
| US6475725B1 (en) | 1997-06-20 | 2002-11-05 | Baxter Aktiengesellschaft | Recombinant cell clones having increased stability and methods of making and using the same |
| AT407255B (de) | 1997-06-20 | 2001-02-26 | Immuno Ag | Rekombinanter zellklon mit erhöhter stabilität in serum- und proteinfreiem medium und verfahren zur gewinnung des stabilen zellklons |
| US6391257B1 (en) | 1998-08-19 | 2002-05-21 | Prestone Products Corporation | Antifreeze compositions comprising carboxylic acid and cyclohexenoic acid |
| EP1103610A1 (en) | 1999-11-26 | 2001-05-30 | Introgene B.V. | Production of vaccines from immortalised mammalian cell lines |
| US6544424B1 (en) | 1999-12-03 | 2003-04-08 | Refined Technology Company | Fluid filtration system |
| US6544788B2 (en) | 2001-02-15 | 2003-04-08 | Vijay Singh | Disposable perfusion bioreactor for cell culture |
| US20030054331A1 (en) * | 2001-09-14 | 2003-03-20 | Stemsource, Inc. | Preservation of non embryonic cells from non hematopoietic tissues |
| JP2007525984A (ja) * | 2004-03-05 | 2007-09-13 | ディーエスエム アイピー アセッツ ビー.ブイ. | 連続的灌流および交互接線流による細胞培養の方法 |
| US20060166364A1 (en) * | 2004-12-22 | 2006-07-27 | Introgen, Inc. | Use of flexible bag containers for viral production |
| JP5020935B2 (ja) * | 2005-04-08 | 2012-09-05 | アルゴス セラピューティクス,インコーポレイティド | 樹状細胞組成物および方法 |
| SI2634243T1 (en) * | 2006-07-14 | 2018-01-31 | Patheon Holdings I B.V. | Improved process for the culturing of cells |
| KR101838302B1 (ko) * | 2009-07-06 | 2018-03-13 | 제넨테크, 인크. | 진핵 세포의 배양 방법 |
| SG182611A1 (en) * | 2010-01-22 | 2012-08-30 | Lonza Walkersville Inc | High yield method and apparatus for volume reduction and washing of therapeutic cells using tangential flow filtration |
| WO2011140241A2 (en) * | 2010-05-04 | 2011-11-10 | The General Hospital Corporation | Methods and compositions for preserving tissues and organs |
| CN103415610B (zh) * | 2011-03-18 | 2016-10-19 | 通用电气健康护理生物科学股份公司 | 用于培养细胞的弹性袋 |
| WO2013006461A1 (en) | 2011-07-01 | 2013-01-10 | Biogen Idec Ma Inc. | Cholesterol-based media supplementals for cell culture |
| TWI656839B (zh) | 2013-03-15 | 2019-04-21 | 健臻公司 | 高密度細胞儲存方法 |
| DK3193594T3 (da) | 2014-09-18 | 2021-09-27 | Genzyme Corp | Fremgangsmåder til frembringelse af cellebank med ultrahøj densitet |
-
2014
- 2014-03-14 TW TW103109317A patent/TWI656839B/zh active
- 2014-03-14 AU AU2014228275A patent/AU2014228275B2/en active Active
- 2014-03-14 MX MX2015011965A patent/MX369521B/es active IP Right Grant
- 2014-03-14 SG SG11201506344TA patent/SG11201506344TA/en unknown
- 2014-03-14 WO PCT/US2014/027757 patent/WO2014143691A1/en not_active Ceased
- 2014-03-14 EP EP21194097.8A patent/EP4008768A1/en active Pending
- 2014-03-14 US US14/212,607 patent/US10188099B2/en active Active
- 2014-03-14 KR KR1020157027627A patent/KR102282939B1/ko active Active
- 2014-03-14 EP EP14723186.4A patent/EP2970843B1/en not_active Revoked
- 2014-03-14 SG SG10201707554WA patent/SG10201707554WA/en unknown
- 2014-03-14 JP JP2016502533A patent/JP6742902B2/ja active Active
- 2014-03-14 ES ES14723186T patent/ES2894633T3/es active Active
- 2014-03-14 AR ARP140101058A patent/AR095354A1/es unknown
- 2014-03-14 CA CA2906600A patent/CA2906600A1/en active Pending
- 2014-03-14 CN CN202011052490.1A patent/CN112410279A/zh active Pending
- 2014-03-14 KR KR1020217023366A patent/KR20210095233A/ko not_active Ceased
- 2014-03-14 HU HUE14723186A patent/HUE056073T2/hu unknown
- 2014-03-14 BR BR112015021189-5A patent/BR112015021189B1/pt active IP Right Grant
- 2014-03-14 DK DK14723186.4T patent/DK2970843T3/da active
- 2014-03-14 RU RU2015143439A patent/RU2668796C2/ru active
- 2014-03-14 CN CN201480015761.2A patent/CN105102605A/zh active Pending
-
2015
- 2015-09-08 IL IL241339A patent/IL241339B/en active IP Right Grant
-
2018
- 2018-12-13 US US16/219,332 patent/US20190223433A1/en not_active Abandoned
-
2019
- 2019-06-18 IL IL267468A patent/IL267468A/en unknown
-
2021
- 2021-11-16 CY CY20211100991T patent/CY1125278T1/el unknown
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