[go: up one dir, main page]

DK2945957T3 - Nye vand-opløselige kompleksdannere og tilsvarende lanthanidkomplekser - Google Patents

Nye vand-opløselige kompleksdannere og tilsvarende lanthanidkomplekser Download PDF

Info

Publication number
DK2945957T3
DK2945957T3 DK14705819.2T DK14705819T DK2945957T3 DK 2945957 T3 DK2945957 T3 DK 2945957T3 DK 14705819 T DK14705819 T DK 14705819T DK 2945957 T3 DK2945957 T3 DK 2945957T3
Authority
DK
Denmark
Prior art keywords
complexing agents
new water
lanthanide complexes
soluble complexing
corresponding lanthanide
Prior art date
Application number
DK14705819.2T
Other languages
English (en)
Inventor
Laurent Lamarque
David Parker
Stephen J Butler
Martina Delbianco
Original Assignee
Cisbio Bioassays
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cisbio Bioassays filed Critical Cisbio Bioassays
Application granted granted Critical
Publication of DK2945957T3 publication Critical patent/DK2945957T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/30Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/32Esters thereof
    • C07F9/3205Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/3229Esters of aromatic acids (P-C aromatic linkage)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D255/00Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
    • C07D255/02Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/003Compounds containing elements of Groups 3 or 13 of the Periodic Table without C-Metal linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/58Pyridine rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/06Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/10Non-macromolecular compounds
    • C09K2211/1003Carbocyclic compounds
    • C09K2211/1007Non-condensed systems
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/10Non-macromolecular compounds
    • C09K2211/1018Heterocyclic compounds
    • C09K2211/1025Heterocyclic compounds characterised by ligands
    • C09K2211/1074Heterocyclic compounds characterised by ligands containing more than three nitrogen atoms as heteroatoms
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/18Metal complexes
    • C09K2211/182Metal complexes of the rare earth metals, i.e. Sc, Y or lanthanide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Materials Engineering (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK14705819.2T 2013-01-16 2014-01-16 Nye vand-opløselige kompleksdannere og tilsvarende lanthanidkomplekser DK2945957T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1350374A FR3000960B1 (fr) 2013-01-16 2013-01-16 Nouveaux agents complexants hydrosolubles et complexes de lanthanide correspondants
PCT/FR2014/050085 WO2014111661A1 (fr) 2013-01-16 2014-01-16 Nouveaux agents complexants hydrosolubles et complexes de lanthanide correspondants

Publications (1)

Publication Number Publication Date
DK2945957T3 true DK2945957T3 (da) 2024-01-29

Family

ID=48083336

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14705819.2T DK2945957T3 (da) 2013-01-16 2014-01-16 Nye vand-opløselige kompleksdannere og tilsvarende lanthanidkomplekser

Country Status (5)

Country Link
US (1) US9920082B2 (da)
EP (1) EP2945957B1 (da)
DK (1) DK2945957T3 (da)
FR (1) FR3000960B1 (da)
WO (1) WO2014111661A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170313936A1 (en) * 2014-10-29 2017-11-02 Dhr Finland New chromophoric structures for macrocyclic lanthanide chelates
FR3045053B1 (fr) * 2015-12-09 2018-01-05 Cisbio Bioassays Agents complexants hydrosolubles a base de triazapyridinophane et complexes de lanthanide fluorescents correspondants
FR3067349B1 (fr) * 2017-06-12 2020-12-04 Cisbio Bioassays Nouveaux agents mono et di-antennes complexants hydrosolubles et complexes de lanthanide correspondants
FR3067712B1 (fr) 2017-06-14 2019-08-02 Cisbio Bioassays Nouveaux agents complexants de type trimethoxyphenyl pyridine hydrosolubles et complexes de lanthanide correspondants
FR3092115B1 (fr) 2019-01-30 2021-11-12 Cisbio Bioassays analogues de GTP fluorescents et utilisation
CN111961078B (zh) * 2020-08-28 2022-06-10 江西理工大学 一种三氟甲基吡啶吡唑铜[i]双核配合物刺激响应发光变色材料的制备方法
CN111892625B (zh) * 2020-08-28 2022-06-10 江西理工大学 一种吡啶吡唑铜[i]双核配合物刺激响应发光变色材料的制备方法
EP3992182A1 (en) 2020-10-28 2022-05-04 Cisbio Bioassays Europium(iii) complexes as ph sensors
TW202310925A (zh) 2021-05-04 2023-03-16 美商沙坎公司 強結合金屬螯合樹脂
US12331155B2 (en) 2021-05-04 2025-06-17 Sachem, Inc. Strong binding metal-chelating resins using macrocycle molecules
CN119192070B (zh) * 2024-07-18 2025-10-31 蚌埠医科大学 一种双光子荧光染料及其制备方法和应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4859777A (en) 1981-07-01 1989-08-22 Eastman Kodak Company Terpyridine chelating agents
US4761481A (en) 1985-03-18 1988-08-02 Baxter Travenol Laboratories, Inc. Substituted pyridine derivatives
SE8502573D0 (sv) * 1985-05-23 1985-05-23 Jouko Kanakre Fluorescent lanthanide chelates useful as labels of physiologically active materials
GB8719041D0 (en) 1987-08-12 1987-09-16 Parker D Conjugate compounds
FR2624862B1 (fr) * 1987-12-18 1990-06-08 Oris Ind Cryptates de terres rares, procedes d'obtention, intermediaires de synthese et application a titre de marqueurs fluorescents
US5202423A (en) 1988-07-08 1993-04-13 Wallac Oy Terpyridine derivatives
US4921195A (en) 1989-01-03 1990-05-01 Clark Emmit S Plastic bag stand
US5216134A (en) 1989-10-23 1993-06-01 Wallac Oy Spectrofluorometric method and compounds that are of value for the method
FR2680787B1 (fr) 1991-08-30 1994-11-04 Cis Bio Int Complexes macrocycliques de terres rares et leur utilisation pour reduire les interferences dans un dosage par fluorescence.
US5622821A (en) 1994-06-29 1997-04-22 The Regents Of The University Of California Luminescent lanthanide chelates and methods of use
FR2810406B1 (fr) 2000-06-15 2002-09-20 Cis Bio Int Nouveaux cryptates de terre rare peu sensibles a l'extinction de fluorescence
US7074570B2 (en) 2001-05-23 2006-07-11 Ge Healthcare Bio-Sciences Ab Peptide fragmentation
EP1658282B1 (en) * 2003-08-29 2010-10-27 Wallac Oy Novel chelating agents and chelates and their use
CA2550074A1 (en) * 2003-12-18 2005-06-30 Wallac Oy Novel chelating agents and highly luminescent and stable chelates and their use
FR2894904B1 (fr) 2005-12-20 2009-07-10 Valeo Vision Sa Dispositif d'eclairage ou de signalisation a guide optique pour vehicule automobile
WO2007128874A1 (en) * 2006-05-05 2007-11-15 Wallac Oy Biomolecule labeling reactants based on azacycloalkanes and conjugates derived thereof
DK2423201T3 (da) 2006-08-15 2018-01-15 Univ California Luminescerende makrocykliske lanthanidkomplekser
FR2978149B1 (fr) * 2011-07-18 2014-01-10 Cisbio Bioassays Nouveaux agents complexants et complexes de lanthanide correspondant, et leur utilisation comme marqueurs luminescents

Also Published As

Publication number Publication date
EP2945957A1 (fr) 2015-11-25
FR3000960A1 (fr) 2014-07-18
FR3000960B1 (fr) 2015-03-06
US9920082B2 (en) 2018-03-20
EP2945957B1 (fr) 2023-11-08
WO2014111661A1 (fr) 2014-07-24
US20150361116A1 (en) 2015-12-17

Similar Documents

Publication Publication Date Title
DK2945957T3 (da) Nye vand-opløselige kompleksdannere og tilsvarende lanthanidkomplekser
HUS2400023I1 (hu) Készítmények és módszerek anémia kezelésére
DK3043784T3 (da) Arylethere og anvendelser deraf
DK3027310T3 (da) Blandingsmetaljernoxider og anvendelser deraf
EP2982411A4 (en) MAGNETIC STIMULATION DEVICE
HRP20190126T1 (hr) Uređaj za razvlaživanje
DK3003039T3 (da) Methyl/fluor-pyridinyl-metoxy-substituerede pyridinon-pyridinyl-forbindelser og fluor-pyrimidinyl-metoxy-substituerede pyridinon-pyridinyl-forbindelser
DK2971476T3 (da) Dobbelt magnetsensoraktiveringsenhed
DK3063144T3 (da) Antiparasitære og pesticid-isoxazolinforbindelser
DK2962100T3 (da) Tuberkulosebiomarkører og anvendelser deraf
DK3079476T3 (da) Syreopløselige kobber-ammonium-komplekser og kobber-zink-ammonium-komplekser, sammensætninger, præparat, metoder og anvendelse
DK3077467T3 (da) Sikkativsammensætning og anvendelse deraf
DK3030549T3 (da) Pyridazinonforbindelser og anvendelser deraf
DK3029038T3 (da) Tetrazolinonforbindelse og anvendelse deraf
DK2964767T3 (da) Toksingener og fremgangsmåder til anvendelse deraf
DK2807160T3 (da) Antifibrotiske forbindelser og anvendelser deraf
EP2983653A4 (en) NDGA POLYMERS AND METAL COMPLEXES THEREOF
DK3071563T3 (da) Midler mod cancer og fremstilling deraf
DK2951208T3 (da) Anti-cd83 antistoffer og anvendelse deraf
DE112013004610A5 (de) Metallkomplexe
DK3003298T3 (da) Antifibrogene forbindelser, fremgangsmåder og anvendelser deraf
BR302014001901S1 (pt) Configuração aplicada em organizador
EP3069712A4 (en) TRANSDERMAL COLLOID SOLVENT
DK3068428T3 (da) Annexin-ii-variant-sammensætninger og fremgangsmåder
DK2999558T3 (da) Stempelholder og stempelkonfigurationer