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DK2890394T3 - Stabiliserede proteiner til immunisering mod Staphylococcus aureus - Google Patents

Stabiliserede proteiner til immunisering mod Staphylococcus aureus Download PDF

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Publication number
DK2890394T3
DK2890394T3 DK13753327.9T DK13753327T DK2890394T3 DK 2890394 T3 DK2890394 T3 DK 2890394T3 DK 13753327 T DK13753327 T DK 13753327T DK 2890394 T3 DK2890394 T3 DK 2890394T3
Authority
DK
Denmark
Prior art keywords
staphylococcus aureus
immunization against
against staphylococcus
stabilized proteins
stabilized
Prior art date
Application number
DK13753327.9T
Other languages
English (en)
Inventor
Fabio Bagnoli
Fabiana Falugi
Guido Grandi
Massimo Mariani
Mikkel Nissum
Michele Pallaoro
Silvana Savino
Original Assignee
Glaxosmithkline Biologicals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa
Application granted granted Critical
Publication of DK2890394T3 publication Critical patent/DK2890394T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/085Staphylococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DK13753327.9T 2012-08-31 2013-08-29 Stabiliserede proteiner til immunisering mod Staphylococcus aureus DK2890394T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261695723P 2012-08-31 2012-08-31
PCT/EP2013/067853 WO2014033190A1 (en) 2012-08-31 2013-08-29 Stabilised proteins for immunising against staphylococcus aureus

Publications (1)

Publication Number Publication Date
DK2890394T3 true DK2890394T3 (da) 2019-07-15

Family

ID=49036594

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13753327.9T DK2890394T3 (da) 2012-08-31 2013-08-29 Stabiliserede proteiner til immunisering mod Staphylococcus aureus

Country Status (15)

Country Link
US (1) US9926344B2 (da)
EP (1) EP2890394B1 (da)
JP (1) JP6435261B2 (da)
CN (2) CN110563818A (da)
CY (1) CY1121944T1 (da)
DK (1) DK2890394T3 (da)
ES (1) ES2737024T3 (da)
HR (1) HRP20191166T1 (da)
HU (1) HUE044211T2 (da)
LT (1) LT2890394T (da)
PL (1) PL2890394T3 (da)
PT (1) PT2890394T (da)
SI (1) SI2890394T1 (da)
TR (1) TR201910573T4 (da)
WO (1) WO2014033190A1 (da)

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ES2769647T3 (es) 2014-03-26 2020-06-26 Glaxosmithkline Biologicals Sa Antígenos estafilocócicos mutantes
EP3538266B1 (en) 2016-11-14 2024-08-21 Lilac Solutions, Inc. Lithium extraction with coated ion exchange particles
JP6916042B2 (ja) * 2017-06-09 2021-08-11 株式会社明治 抗原特異的インターフェロンγ産生促進用組成物
EP3661619A4 (en) 2017-08-02 2021-05-05 Lilac Solutions, Inc. LITHIUM EXTRACTION WITH POROUS ION EXCHANGE BEADS
EP3661620A4 (en) 2017-08-02 2021-05-12 Lilac Solutions, Inc. Ion exchange system for lithium extraction
JP7427598B2 (ja) 2018-02-28 2024-02-05 ライラック ソリューションズ,インク. リチウム抽出用の粒子トラップを備えたイオン交換反応器
JP2023514803A (ja) 2020-01-09 2023-04-11 ライラック ソリューションズ,インク. 望ましくない金属を分離するための方法
CN111595658B (zh) * 2020-06-06 2023-11-14 宾傲 一种提取细胞中蛋白的裂解液及其制备方法
JP2023529444A (ja) 2020-06-09 2023-07-10 ライラック ソリューションズ,インク. スケール物質存在下におけるリチウム抽出
EP4247759A1 (en) 2020-11-20 2023-09-27 Lilac Solutions, Inc. Lithium production with volatile acid
AR125722A1 (es) 2021-04-23 2023-08-09 Lilac Solutions Inc Dispositivos de intercambio iónico para la extracción de litio
WO2023192192A1 (en) 2022-03-28 2023-10-05 Lilac Solutions, Inc. Lithium extraction enhanced by an alternate phase
WO2023192623A2 (en) 2022-04-01 2023-10-05 Lilac Solutions, Inc. Extraction of lithium with chemical additives

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ES2154627T3 (es) 1988-08-24 2001-04-16 American Cyanamid Co Estabilizacion de somatotropinas mediante la modificacion de restos de cisteina utilizando mutagenesis de localizacion dirigida o derivatizacion quimica.
CA2017507C (en) 1989-05-25 1996-11-12 Gary Van Nest Adjuvant formulation comprising a submicron oil droplet emulsion
US5874238A (en) 1993-02-26 1999-02-23 Immtech International Inc. Mutant protein and methods and materials for making and using it
WO1995011700A1 (en) 1993-10-29 1995-05-04 Pharmos Corp. Submicron emulsions as vaccine adjuvants
US6080725A (en) 1997-05-20 2000-06-27 Galenica Pharmaceuticals, Inc. Immunostimulating and vaccine compositions employing saponin analog adjuvants and uses thereof
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AU2001274853B2 (en) * 2000-05-16 2007-03-22 Bolder Biotechnology, Inc. Methods for refolding proteins containing free cysteine residues
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WO2010119343A2 (en) * 2009-04-14 2010-10-21 Novartis Ag Compositions for immunising against staphylococcus aureus
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EP2793939A1 (en) 2011-12-23 2014-10-29 Novartis AG Stable compositions for immunising against staphylococcus aureus

Also Published As

Publication number Publication date
SI2890394T1 (sl) 2019-06-28
EP2890394B1 (en) 2019-05-01
JP2015528455A (ja) 2015-09-28
US9926344B2 (en) 2018-03-27
HUE044211T2 (hu) 2019-10-28
PL2890394T3 (pl) 2019-12-31
CN104619336A (zh) 2015-05-13
ES2737024T3 (es) 2020-01-09
JP6435261B2 (ja) 2018-12-05
WO2014033190A1 (en) 2014-03-06
CY1121944T1 (el) 2020-10-14
CN110563818A (zh) 2019-12-13
LT2890394T (lt) 2019-07-25
TR201910573T4 (tr) 2019-08-21
PT2890394T (pt) 2019-07-15
US20150203542A1 (en) 2015-07-23
EP2890394A1 (en) 2015-07-08
HRP20191166T1 (hr) 2019-10-04

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