DK2731650T3 - Drivmekanisme til en lægemiddelfremføringsanordning - Google Patents
Drivmekanisme til en lægemiddelfremføringsanordning Download PDFInfo
- Publication number
- DK2731650T3 DK2731650T3 DK12733747.5T DK12733747T DK2731650T3 DK 2731650 T3 DK2731650 T3 DK 2731650T3 DK 12733747 T DK12733747 T DK 12733747T DK 2731650 T3 DK2731650 T3 DK 2731650T3
- Authority
- DK
- Denmark
- Prior art keywords
- piston rod
- drive mechanism
- cartridge
- exendin
- stop
- Prior art date
Links
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M5/31513—Piston constructions to improve sealing or sliding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
- A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
- A61M5/31505—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
- A61M2005/31506—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit formed as a single piece, e.g. moulded
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
- A61M5/31505—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Claims (11)
1. Drivmekanisme til en lægemiddelfremføringsanordning, der omfatter: - en stempelstang (44; 70), der udgår i en aksial retning (34, 36) til operabel kobling med et stempel (28) på en patron (26), hvilken stempelstang (44; 60; 70) er indrettet til at udøve et distalt rettet tryk på stemplet (28) til udstødning af et væskeformigt medikament fra patronen (26), - en huskomponent (20) til at rumme stempelstangen (44; 60; 70), som har en styredel (40), der udgår i et lateralt plan og er i indgreb med stempelstangen (44; 60; 70) til styring af denne i aksial retning i forhold til huskomponenten (20), hvor styredelen (40) og stempelstangen (44; 60; 70) er i gevindindgreb, og - mindst én aktiveringlås (48; 52; 62; 72) til at gå i indgreb med stempelstangen (44; 60; 70) til hindring af en proksimalt rettet bevægelse af stempelstangen (44; 60; 70) i forhold til huskomponenten (20), der er kendetegnet ved, at stempelstangen (44; 60; 70) omfatter mindst én radialt indadgående forsænkning (48; 62; 72) til at gå i indgreb med mindst ét radialt indadgående stopelement (52) på aktueringslåsen, og - hvor styredelen (40) omfatter flere af stopelementerne (52), der er anbragt omkring omkredsen af stempelstangen (44; 60; 70) .
2. Drivmekanisme ifølge krav 1, hvor aktiveringslåsen omfatter mindst ét distalt og radialt indadgående stopelement (52) til at gå i indgreb med en forsænket struktur (48; 62; 72) på stempelstangen (44; 60; 70).
3. Drivmekanisme ifølge et hvilket som helst af ovennævnte krav, hvor det mindst ene stopelement (52) omfatter et elastisk deformerbart fjederelement.
4. Drivmekanisme ifølge krav 1 til 3, hvor stempelstangen (44) omfatter et ydre gevind (46) til at samvirke med et indre gevind (42) på styredelen (40) og yderligere omfatter adskillige furer (48), der strækker sig langs omkredsen af stempelstangen (44) og har en fureafstand, der adskiller sig fra fureafstanden på det ydre gevind (46).
5. Drivmekanisme ifølge krav 4, hvor furerne (48) udgår i det væsentlige vinkelret på forlængelsen af stempelstangen (44) .
6. Drivmekanisme ifølge krav 4 eller 5, hvor flere stopelementer (52) er anbragt langs omkredsen af en distal ende af det indre gevind (42) på styredelen (40) og strækker sig i distal retning (34) radialt indad.
7. Drivmekanisme ifølge krav 4 til 6, hvor stopelementerne (52) er formet som en integreret del af styredelen (40).
8. Drivmekanisme ifølge et hvilket som helst af ovennævnte krav, hvor forsænkningerne (62) omfatter en radialt indadgående stopflade (64; 74, 76) til at gå i indgreb med en lateral sidekant (56) af stopelementet (52).
9. Drivmekanisme ifølge et hvilket som helst af ovennævnte krav, hvor stopelementet (52) går i indgreb med stempelstangen (44; 70) med en lavere sidekant (54), der vender i distal retning (34).
10. Lægemiddelfremføringsanordning til indstilling og dispensering af en dosis af et medikament, der omfatter: - en drivmekanisme ifølge et hvilket som helst af ovennævnte krav og - en patronholder (30) til at rumme en patron (26), der er fyldt med et medikament, der skal dispenseres.
11. Lægemiddelfremføringsanordning ifølge krav 10, der omfatter en patron (26), der er mindst delvist fyldt med et medikament.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11173935 | 2011-07-14 | ||
| PCT/EP2012/063636 WO2013007769A1 (en) | 2011-07-14 | 2012-07-12 | Drive mechanism of a drug delivery device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2731650T3 true DK2731650T3 (da) | 2016-01-18 |
Family
ID=45531614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK12733747.5T DK2731650T3 (da) | 2011-07-14 | 2012-07-12 | Drivmekanisme til en lægemiddelfremføringsanordning |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9364616B2 (da) |
| EP (1) | EP2731650B1 (da) |
| JP (1) | JP6073311B2 (da) |
| CA (1) | CA2840943A1 (da) |
| DK (1) | DK2731650T3 (da) |
| WO (1) | WO2013007769A1 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH707217A2 (de) | 2014-02-26 | 2014-04-30 | Tecpharma Licensing Ag | Injektionsvorrichtung zur Verabreichung eines fluiden Produkts. |
| US11135358B2 (en) | 2015-09-18 | 2021-10-05 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8713810D0 (en) * | 1987-06-12 | 1987-07-15 | Hypoguard Uk Ltd | Measured dose dispensing device |
| US4973318A (en) * | 1988-02-10 | 1990-11-27 | D.C.P. Af 1988 A/S | Disposable syringe |
| US5578015A (en) * | 1989-09-18 | 1996-11-26 | Robb Pascal Patent Limited | Safety syringe incorporating automatic needle holder release |
| US5545147A (en) | 1992-10-20 | 1996-08-13 | Eli Lilly And Company | Anti-backup improvement for hypodermic syringes |
| US6086568A (en) * | 1999-10-15 | 2000-07-11 | Becton Dickinson And Company | Syringe plunger rod for retracting needle syringe |
| WO2003080160A1 (en) * | 2002-03-18 | 2003-10-02 | Eli Lilly And Company | Medication dispensing apparatus with gear set for mechanical advantage |
| JP2007503944A (ja) | 2003-09-03 | 2007-03-01 | ノボ・ノルデイスク・エー／エス | ねじ山付きのロッド及びナットアセンブリ |
| WO2006045525A1 (en) * | 2004-10-21 | 2006-05-04 | Novo Nordisk A/S | Injection device with a processor for collecting ejection information |
| US7988675B2 (en) * | 2005-12-08 | 2011-08-02 | West Pharmaceutical Services Of Delaware, Inc. | Automatic injection and retraction devices for use with pre-filled syringe cartridges |
| US7846135B2 (en) * | 2006-02-24 | 2010-12-07 | Midland Medical Holding LLC | Retractable needle syringe with needle trap |
| JP2010503430A (ja) * | 2006-09-15 | 2010-02-04 | テクファーマ・ライセンシング・アクチェンゲゼルシャフト | 低損失駆動部を備える注射装置 |
| US8647309B2 (en) * | 2008-05-02 | 2014-02-11 | Sanofi-Aventis Deutschland Gmbh | Medication delivery device |
| WO2009146996A1 (en) | 2008-06-05 | 2009-12-10 | Shl Group Ab | Pressure relieve mechanism for a medical delivery device |
| CA2745077A1 (en) | 2008-12-04 | 2010-06-10 | Sanofi-Aventis Deutschland Gmbh | Injection device with holding means to prevent unintentional movements of piston rod |
| US9616175B2 (en) * | 2009-07-08 | 2017-04-11 | Novo Nordisk A/S | Frost protected injection device |
| EP2475411B1 (en) * | 2009-09-07 | 2014-12-31 | Sanofi-Aventis Deutschland GmbH | Drive mechanism for drug delivery device |
| US8986259B2 (en) * | 2010-03-31 | 2015-03-24 | Sanofi-Aventis Deutschland Gmbh | Piston rod assembly for a drug delivery device |
-
2012
- 2012-07-12 CA CA2840943A patent/CA2840943A1/en not_active Abandoned
- 2012-07-12 US US14/130,029 patent/US9364616B2/en active Active
- 2012-07-12 JP JP2014519550A patent/JP6073311B2/ja active Active
- 2012-07-12 WO PCT/EP2012/063636 patent/WO2013007769A1/en not_active Ceased
- 2012-07-12 DK DK12733747.5T patent/DK2731650T3/da active
- 2012-07-12 EP EP12733747.5A patent/EP2731650B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP6073311B2 (ja) | 2017-02-01 |
| WO2013007769A1 (en) | 2013-01-17 |
| US20140142516A1 (en) | 2014-05-22 |
| EP2731650A1 (en) | 2014-05-21 |
| JP2014524803A (ja) | 2014-09-25 |
| EP2731650B1 (en) | 2015-10-21 |
| CA2840943A1 (en) | 2013-01-17 |
| US9364616B2 (en) | 2016-06-14 |
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