DK2616465T3 - Triazin-oxadiazoler - Google Patents
Triazin-oxadiazoler Download PDFInfo
- Publication number
- DK2616465T3 DK2616465T3 DK11757294.1T DK11757294T DK2616465T3 DK 2616465 T3 DK2616465 T3 DK 2616465T3 DK 11757294 T DK11757294 T DK 11757294T DK 2616465 T3 DK2616465 T3 DK 2616465T3
- Authority
- DK
- Denmark
- Prior art keywords
- oxadiazoles
- triazine
- Prior art date
Links
- XHBQDVMILDTMJZ-UHFFFAOYSA-N oxadiazole;triazine Chemical class C1=CON=N1.C1=CN=NN=C1 XHBQDVMILDTMJZ-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5386—1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38215810P | 2010-09-13 | 2010-09-13 | |
| PCT/EP2011/065868 WO2012035023A1 (en) | 2010-09-13 | 2011-09-13 | Triazine-oxadiazoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2616465T3 true DK2616465T3 (da) | 2016-02-01 |
Family
ID=44651777
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK11757294.1T DK2616465T3 (da) | 2010-09-13 | 2011-09-13 | Triazin-oxadiazoler |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US8895733B2 (da) |
| EP (1) | EP2616465B1 (da) |
| JP (1) | JP2013537180A (da) |
| KR (1) | KR101843600B1 (da) |
| CN (1) | CN103221408A (da) |
| AU (1) | AU2011303978B2 (da) |
| BR (1) | BR112013005889A2 (da) |
| CA (1) | CA2812081A1 (da) |
| CL (1) | CL2013000685A1 (da) |
| CO (1) | CO6690768A2 (da) |
| CR (1) | CR20130111A (da) |
| CU (1) | CU20130036A7 (da) |
| DK (1) | DK2616465T3 (da) |
| EA (1) | EA026132B1 (da) |
| ES (1) | ES2559449T3 (da) |
| HR (1) | HRP20160094T1 (da) |
| HU (1) | HUE027256T2 (da) |
| MX (1) | MX2013002864A (da) |
| NZ (1) | NZ608116A (da) |
| PE (1) | PE20131377A1 (da) |
| PH (1) | PH12013500473A1 (da) |
| PL (1) | PL2616465T3 (da) |
| PT (1) | PT2616465E (da) |
| RS (1) | RS54544B1 (da) |
| SG (1) | SG188438A1 (da) |
| SI (1) | SI2616465T1 (da) |
| WO (1) | WO2012035023A1 (da) |
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|---|---|---|---|---|
| EA026132B1 (ru) * | 2010-09-13 | 2017-03-31 | Новартис Аг | Триазиноксадиазолы, фармацевтические композиции на их основе и их применение |
| RU2014121983A (ru) | 2011-10-31 | 2015-12-10 | Ксенон Фармасьютикалз Инк. | Биарильные простоэфирные сульфонамиды и их применение в качестве терапевтических средств |
| US9630929B2 (en) | 2011-10-31 | 2017-04-25 | Xenon Pharmaceuticals Inc. | Benzenesulfonamide compounds and their use as therapeutic agents |
| US8952169B2 (en) | 2012-05-22 | 2015-02-10 | Xenon Pharmaceuticals Inc. | N-substituted benzamides and methods of use thereof |
| CN104797555B (zh) | 2012-07-06 | 2017-12-22 | 基因泰克公司 | N‑取代的苯甲酰胺及其使用方法 |
| EP2922828B1 (en) | 2012-11-21 | 2020-07-08 | PTC Therapeutics, Inc. | 4,6-diamino-pyrimidine derivatives as bmi-1 inhibitors for treating cancer |
| HK1213476A1 (zh) | 2013-03-14 | 2016-07-08 | 基因泰克公司 | 取代的三唑並吡啶及其使用方法 |
| CA2898680A1 (en) | 2013-03-15 | 2014-09-18 | Genentech,Inc. | Substituted benzoxazoles and methods of use thereof |
| TWI692477B (zh) | 2013-08-30 | 2020-05-01 | 美商Ｐｔｃ治療公司 | 經取代嘧啶ｂｍｉ-１抑制劑 |
| WO2015076800A1 (en) | 2013-11-21 | 2015-05-28 | Ptc Therapeutics, Inc. | Substituted pyridine and pyrazine bmi-1 inhibitors |
| US9975878B2 (en) | 2013-11-21 | 2018-05-22 | Ptc Therapeutics, Inc. | Substituted triazine BMI-1 inhibitors |
| CA2931732A1 (en) | 2013-11-27 | 2015-06-04 | Genentech, Inc. | Substituted benzamides and methods of use thereof |
| WO2016007534A1 (en) | 2014-07-07 | 2016-01-14 | Genentech, Inc. | Therapeutic compounds and methods of use thereof |
| PE20180575A1 (es) | 2015-05-22 | 2018-04-04 | Genentech Inc | Benzamidas sustituidas y metodos para utilizarlas |
| MA42683A (fr) | 2015-08-27 | 2018-07-04 | Genentech Inc | Composés thérapeutiques et leurs méthodes utilisation |
| BR112018006189A2 (pt) | 2015-09-28 | 2018-10-09 | Genentech Inc | compostos da fórmula, composição farmacêutica, métodos de tratamento de uma doença, de diminuição do fluxo de íons e de tratamento de prurido em um mamífero, método para tratamento de dores em um mamífero e uso de um composto |
| JP2018535234A (ja) | 2015-11-25 | 2018-11-29 | ジェネンテック， インコーポレイテッド | ナトリウムチャネル遮断薬として有用な置換ベンズアミド |
| CN109071426A (zh) | 2016-03-30 | 2018-12-21 | 基因泰克公司 | 取代的苯甲酰胺及其使用方法 |
| JOP20190072A1 (ar) * | 2016-10-13 | 2019-04-07 | Glaxosmithkline Ip Dev Ltd | مشتقات 1، 3 سيكلوبوتان ثنائي الاستبدال أو آزيتيدين كمثبطات للإنزيم المخلق للبروستاجلاندين d المكون للدم |
| WO2018072602A1 (en) | 2016-10-17 | 2018-04-26 | Genentech, Inc. | Therapeutic compounds and methods of use thereof |
| US11970486B2 (en) | 2016-10-24 | 2024-04-30 | Janssen Pharmaceutica Nv | Compounds and uses thereof |
| JP2020514293A (ja) | 2017-01-06 | 2020-05-21 | ユマニティ セラピューティクス，インコーポレーテッド | 神経障害を治療する方法 |
| JP2020511511A (ja) | 2017-03-24 | 2020-04-16 | ジェネンテック， インコーポレイテッド | ナトリウムチャネル阻害剤としての４−ピペリジン−ｎ−（ピリミジン−４−イル）クロマン−７−スルホンアミド誘導体 |
| CA3083000A1 (en) | 2017-10-24 | 2019-05-02 | Yumanity Therapeutics, Inc. | Compounds and uses thereof |
| JP7569688B2 (ja) | 2017-12-22 | 2024-10-18 | ハイバーセル，インコーポレイテッド | ホスファチジルイノシトールリン酸キナーゼ阻害剤としてのアミノピリジン誘導体 |
| EP3759098A1 (en) | 2018-02-26 | 2021-01-06 | Genentech, Inc. | Pyridine-sulfonamide compounds and their use against pain and related conditions |
| EP3768269B1 (en) | 2018-03-23 | 2025-08-20 | Janssen Pharmaceutica NV | Compounds and uses thereof |
| US10947251B2 (en) | 2018-03-30 | 2021-03-16 | Genentech, Inc. | Therapeutic compounds and methods of use thereof |
| TW202003490A (zh) | 2018-05-22 | 2020-01-16 | 瑞士商赫孚孟拉羅股份公司 | 治療性化合物及其使用方法 |
| US12023335B2 (en) | 2018-08-17 | 2024-07-02 | Ptc Therapeutics, Inc. | Method for treating pancreatic cancer |
| MX2021008903A (es) | 2019-01-24 | 2021-11-04 | Yumanity Therapeutics Inc | Compuestos y usos de los mismos. |
| TW202112767A (zh) | 2019-06-17 | 2021-04-01 | 美商佩特拉製藥公司 | 作為磷脂酸肌醇磷酸激酶抑制劑之胺基吡啶衍生物 |
| EA202192047A1 (ru) | 2019-11-13 | 2021-12-08 | Юманити Терапьютикс, Инк. | Соединения и их применение |
| JP2023519892A (ja) * | 2020-03-27 | 2023-05-15 | ランドス バイオファーマ インコーポレイテッド | Ｐｌｘｄｃ２リガンド |
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| PT72878B (en) | 1980-04-24 | 1983-03-29 | Merck & Co Inc | Process for preparing mannich-base hydroxamic acid pro-drugs for the improved delivery of non-steroidal anti-inflammatory agents |
| EP1187825A1 (en) | 1999-06-07 | 2002-03-20 | Shire Biochem Inc. | Thiophene integrin inhibitors |
| DK2256108T3 (da) | 2002-07-18 | 2016-04-11 | Janssen Pharmaceutica Nv | Substituerede triazinkinaseinhibitorer |
| JP2007524596A (ja) | 2003-02-28 | 2007-08-30 | トランスフォーム・ファーマシューティカルズ・インコーポレイテッド | 共結晶医薬組成物 |
| MXPA06000051A (es) * | 2003-07-02 | 2006-03-21 | Vertex Pharma | Pirimidinas utiles como moduladores de canales ionicos dependientes de voltaje. |
| WO2007109324A2 (en) | 2006-03-21 | 2007-09-27 | Xenon Pharmaceuticals, Inc. | Potent and selective nav 1.7 sodium channel blockers |
| US20080227799A1 (en) | 2006-07-11 | 2008-09-18 | Liotta Dennis C | CXCR4 Antagonists Including Heteroatoms for the Treatment of Medical Disorders |
| US8193194B2 (en) * | 2007-05-25 | 2012-06-05 | Vertex Pharmaceuticals Incorporated | Ion channel modulators and methods of use |
| KR20100037047A (ko) | 2007-06-26 | 2010-04-08 | 렉시컨 파마슈티컬스 인코퍼레이티드 | 세로토닌-매개 질환 및 장애의 치료 방법 |
| TW200911766A (en) | 2007-07-13 | 2009-03-16 | Astrazeneca Ab | New compounds |
| EP2231624A4 (en) | 2007-12-21 | 2011-07-06 | Progenics Pharm Inc | TRIAZINE AND CORRESPONDING COMPOUNDS WITH ANTIVIRAL EFFECT, COMPOSITIONS AND METHOD THEREFOR |
| GB0805477D0 (en) | 2008-03-26 | 2008-04-30 | Univ Nottingham | Pyrimidines triazines and their use as pharmaceutical agents |
| US8236880B2 (en) | 2008-04-23 | 2012-08-07 | Taylor Made Golf Company, Inc. | Compositions comprising an amino triazine and ionomer or ionomer precursor |
| US8633233B2 (en) | 2008-08-06 | 2014-01-21 | Hydra Biosciences, Inc. | Methods and compositions for treating anxiety |
| WO2010022055A2 (en) * | 2008-08-20 | 2010-02-25 | Amgen Inc. | Inhibitors of voltage-gated sodium channels |
| US9334269B2 (en) * | 2010-02-17 | 2016-05-10 | Amgen Inc. | Carboxamides as inhibitors of voltage-gated sodium channels |
| EA026132B1 (ru) * | 2010-09-13 | 2017-03-31 | Новартис Аг | Триазиноксадиазолы, фармацевтические композиции на их основе и их применение |
-
2011
- 2011-09-13 EA EA201390381A patent/EA026132B1/ru not_active IP Right Cessation
- 2011-09-13 RS RS20160045A patent/RS54544B1/sr unknown
- 2011-09-13 AU AU2011303978A patent/AU2011303978B2/en not_active Ceased
- 2011-09-13 ES ES11757294.1T patent/ES2559449T3/es active Active
- 2011-09-13 CN CN2011800544823A patent/CN103221408A/zh active Pending
- 2011-09-13 PH PH1/2013/500473A patent/PH12013500473A1/en unknown
- 2011-09-13 PL PL11757294T patent/PL2616465T3/pl unknown
- 2011-09-13 NZ NZ608116A patent/NZ608116A/en not_active IP Right Cessation
- 2011-09-13 CA CA2812081A patent/CA2812081A1/en not_active Abandoned
- 2011-09-13 MX MX2013002864A patent/MX2013002864A/es not_active Application Discontinuation
- 2011-09-13 JP JP2013527645A patent/JP2013537180A/ja active Pending
- 2011-09-13 PE PE2013000506A patent/PE20131377A1/es not_active Application Discontinuation
- 2011-09-13 SG SG2013016829A patent/SG188438A1/en unknown
- 2011-09-13 SI SI201130707T patent/SI2616465T1/sl unknown
- 2011-09-13 KR KR1020137009331A patent/KR101843600B1/ko not_active Expired - Fee Related
- 2011-09-13 HR HRP20160094TT patent/HRP20160094T1/hr unknown
- 2011-09-13 WO PCT/EP2011/065868 patent/WO2012035023A1/en not_active Ceased
- 2011-09-13 HU HUE11757294A patent/HUE027256T2/en unknown
- 2011-09-13 DK DK11757294.1T patent/DK2616465T3/da active
- 2011-09-13 BR BR112013005889-7A patent/BR112013005889A2/pt not_active IP Right Cessation
- 2011-09-13 PT PT117572941T patent/PT2616465E/pt unknown
- 2011-09-13 EP EP11757294.1A patent/EP2616465B1/en active Active
-
2013
- 2013-03-13 CU CU2013000036A patent/CU20130036A7/es unknown
- 2013-03-13 CO CO13050505A patent/CO6690768A2/es unknown
- 2013-03-13 CL CL2013000685A patent/CL2013000685A1/es unknown
- 2013-03-13 CR CR20130111A patent/CR20130111A/es unknown
- 2013-10-15 US US14/054,221 patent/US8895733B2/en not_active Expired - Fee Related
-
2014
- 2014-10-08 US US14/509,705 patent/US20150025057A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PT2616465E (pt) | 2016-03-09 |
| CA2812081A1 (en) | 2012-03-22 |
| EA201390381A1 (ru) | 2013-08-30 |
| SI2616465T1 (sl) | 2016-02-29 |
| EP2616465A1 (en) | 2013-07-24 |
| RS54544B1 (sr) | 2016-06-30 |
| CN103221408A (zh) | 2013-07-24 |
| KR20130105657A (ko) | 2013-09-25 |
| AU2011303978B2 (en) | 2014-07-03 |
| CO6690768A2 (es) | 2013-06-17 |
| SG188438A1 (en) | 2013-05-31 |
| PL2616465T3 (pl) | 2016-04-29 |
| MX2013002864A (es) | 2013-08-29 |
| HUE027256T2 (en) | 2016-08-29 |
| NZ608116A (en) | 2014-05-30 |
| KR101843600B1 (ko) | 2018-03-29 |
| US20140051676A1 (en) | 2014-02-20 |
| CU20130036A7 (es) | 2013-05-31 |
| PH12013500473A1 (en) | 2013-05-06 |
| JP2013537180A (ja) | 2013-09-30 |
| CL2013000685A1 (es) | 2013-10-04 |
| WO2012035023A1 (en) | 2012-03-22 |
| AU2011303978A1 (en) | 2013-03-21 |
| HRP20160094T1 (hr) | 2016-02-26 |
| ES2559449T3 (es) | 2016-02-12 |
| EP2616465B1 (en) | 2015-11-04 |
| PE20131377A1 (es) | 2013-11-30 |
| BR112013005889A2 (pt) | 2020-08-25 |
| EA026132B1 (ru) | 2017-03-31 |
| US8895733B2 (en) | 2014-11-25 |
| US20150025057A1 (en) | 2015-01-22 |
| CR20130111A (es) | 2013-05-29 |
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