DK2478137T3 - Reduceret kodonmutagenese - Google Patents
Reduceret kodonmutageneseInfo
- Publication number
- DK2478137T3 DK2478137T3 DK10817881.5T DK10817881T DK2478137T3 DK 2478137 T3 DK2478137 T3 DK 2478137T3 DK 10817881 T DK10817881 T DK 10817881T DK 2478137 T3 DK2478137 T3 DK 2478137T3
- Authority
- DK
- Denmark
- Prior art keywords
- mutagenese
- reduced codon
- codon
- reduced
- codon mutagenese
- Prior art date
Links
- 108020004705 Codon Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
- C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/06—Biochemical methods, e.g. using enzymes or whole viable microorganisms
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/562,988 US8383346B2 (en) | 2008-06-13 | 2009-09-18 | Combined automated parallel synthesis of polynucleotide variants |
| PCT/US2009/057507 WO2010144103A1 (en) | 2009-06-11 | 2009-09-18 | Combined automated parallel synthesis of polynucleotide variants |
| US28387709P | 2009-12-09 | 2009-12-09 | |
| PCT/US2010/049251 WO2011035105A1 (en) | 2009-09-18 | 2010-09-17 | Reduced codon mutagenesis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2478137T3 true DK2478137T3 (da) | 2017-11-27 |
Family
ID=43759019
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17190712.4T DK3301208T3 (da) | 2009-09-18 | 2010-09-17 | Reduceret codon-mutagenese |
| DK10817881.5T DK2478137T3 (da) | 2009-09-18 | 2010-09-17 | Reduceret kodonmutagenese |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17190712.4T DK3301208T3 (da) | 2009-09-18 | 2010-09-17 | Reduceret codon-mutagenese |
Country Status (5)
| Country | Link |
|---|---|
| EP (2) | EP3301208B1 (da) |
| DK (2) | DK3301208T3 (da) |
| HU (2) | HUE037123T2 (da) |
| SG (1) | SG179197A1 (da) |
| WO (1) | WO2011035105A1 (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109715817B (zh) | 2016-06-09 | 2022-12-09 | 科德克希思公司 | 用于化合物的羟基化的生物催化剂和方法 |
| EA201990035A1 (ru) | 2016-06-15 | 2019-06-28 | Кодексис, Инк. | Генно-инженерные бета-глюкозидазы и способы глюкозилирования |
| EP3515926B1 (en) | 2016-08-26 | 2023-10-25 | Codexis, Inc. | Engineered imine reductases and methods for the reductive amination of ketone and amine compounds |
| CN114901820B (zh) * | 2019-12-30 | 2024-01-19 | 南京金斯瑞生物科技有限公司 | 构建基因突变文库的方法 |
| WO2025212767A1 (en) * | 2024-04-02 | 2025-10-09 | Watchmaker Genomics, Inc. | Gene variant libraries and methods of use thereof |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| US5837458A (en) | 1994-02-17 | 1998-11-17 | Maxygen, Inc. | Methods and compositions for cellular and metabolic engineering |
| US6335160B1 (en) | 1995-02-17 | 2002-01-01 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
| FI104465B (fi) | 1995-06-14 | 2000-02-15 | Valio Oy | Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö |
| US6326204B1 (en) | 1997-01-17 | 2001-12-04 | Maxygen, Inc. | Evolution of whole cells and organisms by recursive sequence recombination |
| WO1999029902A1 (en) | 1997-12-08 | 1999-06-17 | California Institute Of Technology | Method for creating polynucleotide and polypeptide sequences |
| JP4221100B2 (ja) | 1999-01-13 | 2009-02-12 | エルピーダメモリ株式会社 | 半導体装置 |
| WO2000042561A2 (en) | 1999-01-19 | 2000-07-20 | Maxygen, Inc. | Oligonucleotide mediated nucleic acid recombination |
| WO2001075767A2 (en) | 2000-03-30 | 2001-10-11 | Maxygen, Inc. | In silico cross-over site selection |
| DE60144145D1 (de) | 2000-04-03 | 2011-04-14 | Maxygen Inc | Subtilisin-variante |
| WO2005017141A1 (en) | 2003-08-11 | 2005-02-24 | Codexis, Inc. | Improved halohydrin dehalogenases and related polynucleotides |
| JP2007502124A (ja) | 2003-08-11 | 2007-02-08 | コデクシス， インコーポレイテッド | 改良ケトレダクターゼポリペプチドおよび関連ポリヌクレオチド |
| BRPI0619225A2 (pt) * | 2005-12-01 | 2017-11-07 | Domantis Ltd | monômero de anticorpo de domínio, ligando, ácidos nucleicos isolado e recombinante, vetor, célula hospedeira, método para produzir um monômero de dab de ligando, composição farmacêutica, dispositivo de liberação de medicamento, uso de um monômero de anticorpo de domínio, e, método para tratar uma doença inflamatória, artrite ou doença respiratória |
| WO2008103474A1 (en) * | 2007-02-20 | 2008-08-28 | Anaptysbio, Inc. | Methods of generating libraries and uses thereof |
| WO2009088933A1 (en) * | 2007-12-31 | 2009-07-16 | Xoma Technology Ltd. | Methods and materials for targeted mutagenesis |
| US8383346B2 (en) * | 2008-06-13 | 2013-02-26 | Codexis, Inc. | Combined automated parallel synthesis of polynucleotide variants |
-
2010
- 2010-09-17 WO PCT/US2010/049251 patent/WO2011035105A1/en not_active Ceased
- 2010-09-17 SG SG2012018917A patent/SG179197A1/en unknown
- 2010-09-17 EP EP17190712.4A patent/EP3301208B1/en active Active
- 2010-09-17 DK DK17190712.4T patent/DK3301208T3/da active
- 2010-09-17 HU HUE10817881A patent/HUE037123T2/hu unknown
- 2010-09-17 DK DK10817881.5T patent/DK2478137T3/da active
- 2010-09-17 HU HUE17190712A patent/HUE051913T2/hu unknown
- 2010-09-17 EP EP10817881.5A patent/EP2478137B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3301208B1 (en) | 2020-11-04 |
| HUE037123T2 (hu) | 2018-08-28 |
| DK3301208T3 (da) | 2020-12-14 |
| HUE051913T2 (hu) | 2021-04-28 |
| WO2011035105A1 (en) | 2011-03-24 |
| EP2478137A1 (en) | 2012-07-25 |
| EP2478137A4 (en) | 2013-10-23 |
| SG179197A1 (en) | 2012-04-27 |
| EP2478137B1 (en) | 2017-09-13 |
| EP3301208A1 (en) | 2018-04-04 |
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