DK2442870T3 - Pyrazinooxazepin-derivater. - Google Patents

Pyrazinooxazepin-derivater.

Info

Publication number: DK2442870T3
Authority: DK; Denmark
Prior art keywords: pyrazinooxazepin; derivatives; pyrazinooxazepin derivatives
Prior art date: 2009-06-15

Application number

DK10727154.6T

Other languages

English (en)

Inventor

Shigekazu Sasaki

Tomokazu Kusumoto

Izumi Nomura

Hironobu Maezaki

Original Assignee

Takeda Pharmaceutical

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-06-15

Filing date

2010-06-14

Publication date

2014-06-30

2010-06-14 Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical

2014-06-30 Application granted granted Critical

2014-06-30 Publication of DK2442870T3 publication Critical patent/DK2442870T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Urology & Nephrology (AREA)
Pulmonology (AREA)
Obesity (AREA)
Hematology (AREA)
Child & Adolescent Psychology (AREA)
Surgery (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK10727154.6T 2009-06-15 2010-06-14 Pyrazinooxazepin-derivater. DK2442870T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2009142673		2009-06-15
PCT/JP2010/060408 WO2010147226A1 (en)	2009-06-15	2010-06-14	Pyrazinooxazepine derivatives

Publications (1)

Publication Number	Publication Date
DK2442870T3 true DK2442870T3 (da)	2014-06-30

Family

ID=42561089

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK10727154.6T DK2442870T3 (da)	2009-06-15	2010-06-14	Pyrazinooxazepin-derivater.

Country Status (40)

Country	Link
US (4)	US8318722B2 (da)
EP (1)	EP2442870B1 (da)
JP (2)	JP5579262B2 (da)
KR (1)	KR101768234B1 (da)
CN (1)	CN102458579B (da)
AR (1)	AR077094A1 (da)
AU (1)	AU2010260847B2 (da)
BR (1)	BRPI1011502A2 (da)
CA (1)	CA2765239C (da)
CL (1)	CL2011003154A1 (da)
CO (1)	CO6491037A2 (da)
CR (1)	CR20120021A (da)
CY (1)	CY1115483T1 (da)
DK (1)	DK2442870T3 (da)
DO (1)	DOP2011000393A (da)
EA (1)	EA021079B1 (da)
EC (1)	ECSP12011603A (da)
ES (1)	ES2480275T3 (da)
GE (1)	GEP20146168B (da)
HR (1)	HRP20140589T1 (da)
IL (1)	IL216761A (da)
JO (1)	JO3087B1 (da)
MA (1)	MA33430B1 (da)
ME (1)	ME01835B (da)
MX (1)	MX2011013081A (da)
MY (1)	MY157497A (da)
NZ (1)	NZ597507A (da)
PE (1)	PE20121049A1 (da)
PL (1)	PL2442870T3 (da)
PT (1)	PT2442870E (da)
RS (1)	RS53414B (da)
SG (1)	SG176696A1 (da)
SI (1)	SI2442870T1 (da)
SM (1)	SMT201400080B (da)
TN (1)	TN2011000630A1 (da)
TW (2)	TWI542592B (da)
UA (1)	UA108357C2 (da)
UY (1)	UY32707A (da)
WO (1)	WO2010147226A1 (da)
ZA (1)	ZA201109370B (da)

Families Citing this family (10)

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JP5528699B2 (ja) *	2006-05-16	2014-06-25	武田薬品工業株式会社	縮合複素環化合物およびその用途
AR077094A1 (es) *	2009-06-15	2011-08-03	Takeda Pharmaceutical	Derivados de pirazinooxazepina, composiciones farmaceuticas y su uso en el tratamiento de un sintoma del aparato urinario inferior, obesidad y/o prolapso de organos
US20130267500A1 (en)	2010-09-01	2013-10-10	Arena Pharmaceuticals, Inc.	5-ht2c receptor agonists in the treatment of disorders ameliorated by reduction of norepinephrine level
JP2014201578A (ja) *	2013-04-09	2014-10-27	武田薬品工業株式会社	線維筋痛症治療剤
JP2014214132A (ja) *	2013-04-26	2014-11-17	武田薬品工業株式会社	ニコチン依存症の予防・治療剤
WO2015066344A1 (en)	2013-11-01	2015-05-07	Arena Pharmaceuticals, Inc.	5-ht2c receptor agonists and compositions and methods of use
WO2017026538A1 (en)	2015-08-07	2017-02-16	Takeda Pharmaceutical Company Limited	Production method of pyrazine
WO2017111178A1 (en)	2015-12-24	2017-06-29	Takeda Pharmaceutical Company Limited	Solid preparation
US9985579B2 (en)	2016-04-12	2018-05-29	Preformed Line Products Co.	Mounting assembly for mounting a solar panel
EP3733204A4 (en)	2017-12-27	2021-09-15	Takeda Pharmaceutical Company Limited	THERAPEUTIC AGENT FOR URINARY INCONTINENCE OF STRESS AND FECAL INCONTINENCE

Family Cites Families (22)

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JP2992677B2 (ja)	1995-06-05	1999-12-20	武田薬品工業株式会社	骨形成促進医薬組成物
SE0002754D0 (sv)	2000-07-21	2000-07-21	Pharmacia & Upjohn Ab	New pharmaceutical combination formulation and method of treatment with the combination
ATE433962T1 (de)	2000-11-20	2009-07-15	Biovitrum Ab Publ	Piperazinylpyrazinverbindungen als antagonisten des serotonin-5-ht2-rezeptors
US6699866B2 (en)	2001-04-17	2004-03-02	Sepracor Inc.	Thiazole and other heterocyclic ligands for mammalian dopamine, muscarinic and serotonin receptors and transporters, and methods of use thereof
SE0201544D0 (sv)	2002-05-17	2002-05-17	Biovitrum Ab	Novel compounds and thier use
AU2003243089B2 (en)	2002-06-19	2010-01-07	Biovitrum Ab (Publ)	Novel compounds, their use and preparation
JP4592417B2 (ja)	2002-06-19	2010-12-01	プロキシマゲン・リミテッド	新規方法
EP1591120A4 (en)	2003-01-28	2009-06-10	Takeda Chemical Industries Ltd	RECEPTOR AGONISTS
CL2004000826A1 (es)	2003-04-25	2005-03-04	Pfizer	Uso de un agonista para el receptor 5-ht2c para preparar un medicamento util en el tratamiento de la incontinencia urinaria provocada por estres, con la condicion de que el agonista no sea 1-[6-cloro-5-(trifluorometil)-2-piridinil]piperazina (org-129
HUE028976T2 (en)	2003-06-17	2017-02-28	Arena Pharm Inc	8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride
CN1805939B (zh)	2003-06-17	2010-10-13	艾尼纳制药公司	用于治疗5ht2c受体相关病症的苯并氮杂卓衍生物
JP2006056881A (ja)	2004-07-21	2006-03-02	Takeda Chem Ind Ltd	縮合環化合物
MX2008002180A (es)	2005-09-01	2008-04-22	Lilly Co Eli	2,3,4,5-tetrahidro-1h-benzo[d]azepinas 6-sustituidas como agonistas de receptor 5-ht2c.
FR2895259B1 (fr)	2005-12-22	2008-02-22	Urosphere Sas	Methodes de traitement des incontinences urinaires
JP5528699B2 (ja) *	2006-05-16	2014-06-25	武田薬品工業株式会社	縮合複素環化合物およびその用途
EP2123644B1 (en) *	2007-03-07	2014-12-17	Takeda Pharmaceutical Company Limited	Benzoxazepine derivatives and use thereof
US20090062253A1 (en)	2007-08-31	2009-03-05	Kalypsys, Inc.	Heterocyclodiazepine cannabinoid receptor modulators for treatment of disease
JP5520051B2 (ja)	2007-11-15	2014-06-11	武田薬品工業株式会社	縮合ピリジン誘導体およびその用途
JP5361733B2 (ja)	2007-11-15	2013-12-04	武田薬品工業株式会社	ピリドオキサゼピン誘導体およびその用途
WO2009063993A1 (ja) *	2007-11-15	2009-05-22	Takeda Pharmaceutical Company Limited	縮合ピリジン誘導体およびその用途
US8299103B2 (en)	2009-06-15	2012-10-30	Boehringer Ingelheim International Gmbh	Compounds which selectively modulate the CB2 receptor
AR077094A1 (es) *	2009-06-15	2011-08-03	Takeda Pharmaceutical	Derivados de pirazinooxazepina, composiciones farmaceuticas y su uso en el tratamiento de un sintoma del aparato urinario inferior, obesidad y/o prolapso de organos

2010
- 2010-06-14 AR ARP100102101A patent/AR077094A1/es not_active Application Discontinuation
- 2010-06-14 ME MEP-2014-81A patent/ME01835B/me unknown
- 2010-06-14 MX MX2011013081A patent/MX2011013081A/es active IP Right Grant
- 2010-06-14 RS RS20140373A patent/RS53414B/sr unknown
- 2010-06-14 AU AU2010260847A patent/AU2010260847B2/en not_active Ceased
- 2010-06-14 CA CA2765239A patent/CA2765239C/en not_active Expired - Fee Related
- 2010-06-14 PE PE2011002104A patent/PE20121049A1/es active IP Right Grant
- 2010-06-14 WO PCT/JP2010/060408 patent/WO2010147226A1/en not_active Ceased
- 2010-06-14 TW TW099119242A patent/TWI542592B/zh not_active IP Right Cessation
- 2010-06-14 HR HRP20140589AT patent/HRP20140589T1/hr unknown
- 2010-06-14 JO JOP/2010/0194A patent/JO3087B1/ar active
- 2010-06-14 US US12/814,692 patent/US8318722B2/en not_active Expired - Fee Related
- 2010-06-14 UA UAA201200408A patent/UA108357C2/ru unknown
- 2010-06-14 PL PL10727154T patent/PL2442870T3/pl unknown
- 2010-06-14 PT PT107271546T patent/PT2442870E/pt unknown
- 2010-06-14 US US13/377,918 patent/US9115139B2/en not_active Expired - Fee Related
- 2010-06-14 SI SI201030641T patent/SI2442870T1/sl unknown
- 2010-06-14 MA MA34535A patent/MA33430B1/fr unknown
- 2010-06-14 SG SG2011090149A patent/SG176696A1/en unknown
- 2010-06-14 KR KR1020127000935A patent/KR101768234B1/ko not_active Expired - Fee Related
- 2010-06-14 TW TW104112674A patent/TW201529584A/zh unknown
- 2010-06-14 EP EP10727154.6A patent/EP2442870B1/en active Active
- 2010-06-14 UY UY0001032707A patent/UY32707A/es not_active Application Discontinuation
- 2010-06-14 ES ES10727154.6T patent/ES2480275T3/es active Active
- 2010-06-14 MY MYPI2011006107A patent/MY157497A/en unknown
- 2010-06-14 NZ NZ597507A patent/NZ597507A/xx not_active IP Right Cessation
- 2010-06-14 EA EA201270017A patent/EA021079B1/ru not_active IP Right Cessation
- 2010-06-14 GE GEAP201012529A patent/GEP20146168B/en unknown
- 2010-06-14 BR BRPI1011502A patent/BRPI1011502A2/pt not_active Application Discontinuation
- 2010-06-14 DK DK10727154.6T patent/DK2442870T3/da active
- 2010-06-14 JP JP2012514674A patent/JP5579262B2/ja not_active Expired - Fee Related
- 2010-06-14 CN CN201080036178.1A patent/CN102458579B/zh not_active Expired - Fee Related
2011
- 2011-07-28 US US13/192,845 patent/US8314088B2/en not_active Expired - Fee Related
- 2011-07-28 US US13/192,865 patent/US8324201B2/en not_active Expired - Fee Related
- 2011-12-04 IL IL216761A patent/IL216761A/en not_active IP Right Cessation
- 2011-12-08 TN TNP2011000630A patent/TN2011000630A1/en unknown
- 2011-12-14 CL CL2011003154A patent/CL2011003154A1/es unknown
- 2011-12-14 DO DO2011000393A patent/DOP2011000393A/es unknown
- 2011-12-20 ZA ZA2011/09370A patent/ZA201109370B/en unknown
2012
- 2012-01-13 CO CO12004620A patent/CO6491037A2/es active IP Right Grant
- 2012-01-13 CR CR20120021A patent/CR20120021A/es unknown
- 2012-01-13 EC ECSP12011603 patent/ECSP12011603A/es unknown
- 2012-01-31 JP JP2012019274A patent/JP5579203B2/ja not_active Expired - Fee Related
2014
- 2014-06-25 SM SM201400080T patent/SMT201400080B/xx unknown
- 2014-07-11 CY CY20141100527T patent/CY1115483T1/el unknown

Also Published As

Publication number	Publication date
PT2442870E (pt)	2014-07-16
IL216761A0 (en)	2012-02-29
CR20120021A (es)	2012-03-06
JP2012530051A (ja)	2012-11-29
EP2442870B1 (en)	2014-04-16
JP5579203B2 (ja)	2014-08-27
US20110288291A1 (en)	2011-11-24
EP2442870A1 (en)	2012-04-25
CY1115483T1 (el)	2017-01-04
RS53414B (sr)	2014-12-31
TW201529584A (zh)	2015-08-01
UA108357C2 (xx)	2015-04-27
CN102458579A (zh)	2012-05-16
CL2011003154A1 (es)	2012-06-15
UY32707A (es)	2011-01-31
IL216761A (en)	2016-03-31
GEP20146168B (en)	2014-09-25
HRP20140589T1 (hr)	2014-08-01
ME01835B (me)	2014-12-20
CA2765239A1 (en)	2010-12-23
AU2010260847A1 (en)	2012-01-19
US20100317651A1 (en)	2010-12-16
MX2011013081A (es)	2012-01-20
AR077094A1 (es)	2011-08-03
SG176696A1 (en)	2012-01-30
MY157497A (en)	2016-06-15
US20110282054A1 (en)	2011-11-17
PE20121049A1 (es)	2012-08-22
DOP2011000393A (es)	2012-02-15
US8318722B2 (en)	2012-11-27
US20120135979A1 (en)	2012-05-31
JO3087B1 (ar)	2017-03-15
US9115139B2 (en)	2015-08-25
US8314088B2 (en)	2012-11-20
CN102458579B (zh)	2014-11-05
EA201270017A1 (ru)	2012-07-30
PL2442870T3 (pl)	2014-12-31
BRPI1011502A2 (pt)	2016-03-22
AU2010260847B2 (en)	2016-11-24
ZA201109370B (en)	2012-10-31
SMT201400080B (it)	2014-09-08
CA2765239C (en)	2018-08-07
MA33430B1 (fr)	2012-07-03
TN2011000630A1 (en)	2013-05-24
TW201109338A (en)	2011-03-16
ECSP12011603A (es)	2012-03-30
EA021079B1 (ru)	2015-03-31
SI2442870T1 (sl)	2014-07-31
HK1169623A1 (en)	2013-02-01
JP5579262B2 (ja)	2014-08-27
KR101768234B1 (ko)	2017-08-14
JP2012107032A (ja)	2012-06-07
NZ597507A (en)	2013-09-27
US8324201B2 (en)	2012-12-04
WO2010147226A1 (en)	2010-12-23
TWI542592B (zh)	2016-07-21
CO6491037A2 (es)	2012-07-31
ES2480275T3 (es)	2014-07-25
KR20120034734A (ko)	2012-04-12

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