DK2335370T3 - Organ-på-en-chip-anordning - Google Patents
Organ-på-en-chip-anordningInfo
- Publication number
- DK2335370T3 DK2335370T3 DK09757294.5T DK09757294T DK2335370T3 DK 2335370 T3 DK2335370 T3 DK 2335370T3 DK 09757294 T DK09757294 T DK 09757294T DK 2335370 T3 DK2335370 T3 DK 2335370T3
- Authority
- DK
- Denmark
- Prior art keywords
- organ
- chip device
- chip
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/16—Microfluidic devices; Capillary tubes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/10—Perfusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0663—Whole sensors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Sustainable Development (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Dispersion Chemistry (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Fluid Mechanics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Food Science & Technology (AREA)
- Toxicology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Microscoopes, Condenser (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5876608P | 2008-06-04 | 2008-06-04 | |
| PCT/EP2009/004008 WO2009146911A2 (en) | 2008-06-04 | 2009-06-04 | Organ-on-a-chip-device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2335370T3 true DK2335370T3 (da) | 2014-05-26 |
Family
ID=41398604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK09757294.5T DK2335370T3 (da) | 2008-06-04 | 2009-06-04 | Organ-på-en-chip-anordning |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20110086382A1 (da) |
| EP (3) | EP2730645A3 (da) |
| JP (1) | JP5774477B2 (da) |
| CN (1) | CN102257124B (da) |
| AU (1) | AU2009254177B2 (da) |
| CA (1) | CA2727003C (da) |
| DK (1) | DK2335370T3 (da) |
| RU (1) | RU2517046C2 (da) |
| SG (1) | SG193829A1 (da) |
| WO (1) | WO2009146911A2 (da) |
Families Citing this family (74)
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|---|---|---|---|---|
| KR102140055B1 (ko) | 2008-07-16 | 2020-07-31 | 칠드런'즈 메디컬 센터 코포레이션 | 마이크로채널을 갖는 기관 모방 장치 및 그 사용 및 제조 방법 |
| US9719068B2 (en) | 2010-05-06 | 2017-08-01 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| EP2626411B1 (en) * | 2010-09-30 | 2020-01-01 | National University Corporation Tokyo Medical and Dental University | Method and device for myocardial cell evaluation and myocardial toxicity inspection |
| US20130287613A1 (en) | 2010-10-07 | 2013-10-31 | Vanderbilt University | Peristaltic micropump and related systems and methods |
| WO2014081840A1 (en) * | 2012-11-21 | 2014-05-30 | Vanderbilt University | Organ on chip integration and applications of the same |
| US10023832B2 (en) | 2013-07-16 | 2018-07-17 | Vanderbilt University | Interconnections of multiple perfused engineered tissue constructs and microbioreactors, multi-microformulators and applications of the same |
| CA2828110C (en) | 2011-02-28 | 2020-03-31 | President And Fellows Of Harvard College | Cell culture system |
| EP2714892B1 (en) * | 2011-06-02 | 2018-02-21 | President and Fellows of Harvard College | Methods and uses for ex vivo tissue culture systems |
| WO2013086486A1 (en) * | 2011-12-09 | 2013-06-13 | President And Fellows Of Harvard College | Integrated human organ-on-chip microphysiological systems |
| EP2634251A1 (en) | 2012-02-29 | 2013-09-04 | Technische Universität Berlin | 3D in vitro bi-phasic cartilage-bone construct |
| EP2633870B1 (en) * | 2012-02-29 | 2018-08-01 | Technische Universität Berlin | Method of preparing an artificial tooth primordium in vitro and artificial tooth primordium derived therefrom |
| EP2841941B1 (en) * | 2012-04-26 | 2018-02-14 | TissUse GmbH | Methods for determining and/or monitoring conditions of a three dimensional cell culture system and optical sensor device for conducting said methods |
| PT2712918E (pt) | 2012-09-28 | 2015-02-17 | Tissuse Gmbh | Chip-multi-órgãos com melhor tempo de vida e homeostase |
| US9267938B2 (en) | 2013-03-14 | 2016-02-23 | The Trustees Of The Stevens Institute Of Technology | Ex vivo human multiple myeloma cancer niche and its use as a model for personalized treatment of multiple myeloma |
| US9855554B2 (en) | 2013-07-22 | 2018-01-02 | President And Fellows Of Harvard College | Microfluidic cartridge assembly |
| GB2545287A (en) | 2013-12-20 | 2017-06-14 | Harvard College | Organomimetic devices and methods of use and manufacturing thereof |
| CA2934662C (en) | 2013-12-20 | 2024-02-20 | President And Fellows Of Harvard College | Low shear microfluidic devices and methods of use and manufacturing thereof |
| CN103981096B (zh) * | 2014-05-27 | 2015-11-18 | 东南大学 | 一种两层细胞培养体系器官芯片及其制备方法 |
| EP3149156B1 (en) | 2014-05-28 | 2021-02-17 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into gastric tissues through directed differentiation |
| GB2546424A (en) | 2014-07-14 | 2017-07-19 | Harvard College | Systems and methods for improved performance of fluidic and microfluidic systems |
| WO2016033652A1 (en) | 2014-09-03 | 2016-03-10 | Newsouth Innovations Pty Limited | Microfluidic devices and fabrication |
| US11060067B2 (en) * | 2014-09-30 | 2021-07-13 | D. Lansing Taylor | Human liver microphysiology platform and self assembly liver acinus model and methods of their use |
| JP6804438B2 (ja) | 2014-10-17 | 2020-12-23 | チルドレンズ ホスピタル メディカル センター | 多能性幹細胞を使用するヒト小腸のin vivoモデル、並びにそれを作製、及び使用する方法 |
| RU2584598C1 (ru) * | 2015-03-27 | 2016-05-20 | Общество с ограниченной ответственностью Научно-технический центр "БиоКлиникум" | Микрофлюидный чип для создания клеточных моделей органов млекопитающих |
| EP3279310B1 (en) | 2015-04-03 | 2021-05-05 | National Institute of Advanced Industrial Science and Technology | Cell culture apparatus and cell culture method |
| NL2014840B1 (en) * | 2015-05-21 | 2017-01-31 | Intecrypt B V | Microfluidic device for in vitro 3D cell culture experimentation. |
| RU2592687C1 (ru) * | 2015-06-30 | 2016-07-27 | Евгений Александрович Тоневицкий | Устройство пневматического управления клапанами микрофлюидной системы |
| WO2017019542A1 (en) | 2015-07-24 | 2017-02-02 | President And Fellows Of Harvard College | Radial microfluidic devices and methods of use |
| CN105170205B (zh) * | 2015-09-19 | 2017-01-25 | 大连理工大学 | 一种基于微流控芯片技术构建的仿生芯片 |
| EP3190172B1 (en) * | 2016-01-07 | 2025-05-21 | Vanderbilt University | Interconnections of multiple perfused engineered tissue constructs and microbioreactors, multi-microformulators and applications of the same |
| RU171690U1 (ru) * | 2016-03-24 | 2017-06-09 | Общество с ограниченной ответственностью Научно-технический центр "БиоКлиникум" | Микрофлюидный чип для создания клеточных моделей органов млекопитающих |
| EP3439783A1 (en) * | 2016-04-06 | 2019-02-13 | Fluidic Analytics Limited | Improvements in or relating to flow balancing |
| RU2612904C1 (ru) * | 2016-04-15 | 2017-03-13 | Евгений Александрович Тоневицкий | Способ и микрофлюидный чип для культивирования клеток или клеточной модели |
| EP4177335A1 (en) | 2016-05-05 | 2023-05-10 | Children's Hospital Medical Center | Methods for the in vitro manufacture of gastric fundus tissue and compositions related to same |
| RU2741806C2 (ru) | 2016-06-15 | 2021-01-28 | Миметас Б.В. | Устройство и способы для культивирования клеток |
| US12104174B2 (en) | 2016-09-13 | 2024-10-01 | President And Fellows Of Harvard College | Methods relating to intestinal organ-on-a-chip |
| CA3039980A1 (en) * | 2016-10-14 | 2018-04-19 | Wake Forest University Health Sciences | Multi-organ "body on a chip" apparatus utilizing a common media |
| EP3534976A4 (en) | 2016-11-04 | 2020-09-16 | Children's Hospital Medical Center | PATHOLOGICAL MODELS OF HEPATIC ORGANOIDS AND ASSOCIATED METHODS OF MANUFACTURE AND USE |
| WO2018088856A2 (ko) | 2016-11-10 | 2018-05-17 | 재단법인 아산사회복지재단 | 마이크로유체칩, 삼차원 채널 구조물, 이를 이용한 세포 배양 방법 및 이를 이용한 생리활성 물질의 활성평가 방법 |
| EP3541518A4 (en) * | 2016-11-17 | 2020-09-30 | Cleveland State University | CHIP PLATFORMS FOR MICRO-NETWORK 3D BIO-PRINTING |
| EP3548507A4 (en) | 2016-12-05 | 2020-07-15 | Children's Hospital Medical Center | COLON ORGANOIDS AND PROCESSES FOR THE PREPARATION AND USE THEREOF |
| RU2671476C2 (ru) * | 2016-12-28 | 2018-10-31 | Федеральное государственное бюджетное учреждение "Государственный научный центр Российской Федерации - Федеральный Медицинский биофизический центр имени А.И. Бурназяна Федерального Медико-биологического агентства" (ФГБУ ГНЦ ФМБЦ им. А.И. Бурназяна ФМБА России) | Устройство для двухсторонней децеллюляризации сосудистых графтов различного диаметра и способ оптимизации его работы (варианты) |
| WO2018208332A2 (en) | 2017-02-17 | 2018-11-15 | Koniku, Inc. | Systems for detection |
| EP3609997A4 (en) | 2017-04-14 | 2021-03-03 | Children's Hospital Medical Center | COMPOSITIONS OF STEM CELLS FROM MULTIPLE DONOR CELLS AND THEIR PREPARATION PROCEDURES |
| US11826757B2 (en) * | 2017-08-02 | 2023-11-28 | Wake Forest University Health Sciences | Niches-on-a-chip |
| WO2019060680A1 (en) | 2017-09-22 | 2019-03-28 | The Regents Of The University Of Colorado, A Body Corporate | MICROPHYSIOLOGICAL ORGAN-ON-CHIP SYSTEM |
| EP3694603A4 (en) | 2017-10-10 | 2021-07-14 | Children's Hospital Medical Center | ESOPHAGUS TISSUE AND / OR ORGANOID COMPOSITIONS AND METHOD FOR MANUFACTURING THEREOF |
| DE102017222261B4 (de) | 2017-12-08 | 2019-08-29 | Technische Universität Braunschweig | Herstellungsverfahren für Organ-on-a-Chip Systeme |
| CN108004144B (zh) * | 2017-12-18 | 2021-04-06 | 清华大学深圳研究生院 | 一种含管道网络的器官芯片单元 |
| US12379372B2 (en) | 2017-12-21 | 2025-08-05 | Children's Hospital Medical Center | Digitalized human organoids and methods of using same |
| KR102820005B1 (ko) | 2018-02-02 | 2025-06-12 | 웨이크 포리스트 유니버시티 헬스 사이언시즈 | 면역요법 관련 오가노이드 및 그의 제조 및 사용 방법 |
| US11679546B2 (en) | 2018-02-09 | 2023-06-20 | The Regents Of The University Of Colorado, A Body Corporate | Bioprinter and methods of manufacturing an organomimetic device |
| CN110305787A (zh) * | 2018-03-27 | 2019-10-08 | 华东理工大学 | 一种体内力学环境模拟装置 |
| US11480560B2 (en) | 2018-06-11 | 2022-10-25 | The Regents Of The University Of Colorado, A Body Corporate | Delivery of aerosolized respiratory pathogens |
| KR102887406B1 (ko) | 2018-07-26 | 2025-11-19 | 칠드런즈 호스피탈 메디칼 센터 | 간-담도-췌장 조직 및 이를 제조하는 방법 |
| WO2020056158A1 (en) | 2018-09-12 | 2020-03-19 | Children's Hospital Medical Center | Organoid compositions for the production of hematopoietic stem cells and derivatives thereof |
| WO2020081740A1 (en) | 2018-10-17 | 2020-04-23 | Northwestern University | Tissue culture platform having multiple well chambers fluidically coupled via microfluidic channels and selector valves |
| CN109576155B (zh) * | 2018-12-18 | 2021-12-07 | 大连理工大学 | 通用神经系统芯片 |
| US12024696B2 (en) * | 2019-05-08 | 2024-07-02 | Molecular Devices (Austria) GmbH | System and method for organoid culture |
| CN110283724B (zh) * | 2019-07-09 | 2022-07-29 | 汇芯(北京)科技有限公司 | 一种高通量类器官表型筛查系统和方法 |
| KR102830487B1 (ko) | 2020-01-16 | 2025-07-08 | 삼성전자주식회사 | 세포 클러스터를 이용한 생체 전자약 장치 |
| CN111657861B (zh) * | 2020-06-04 | 2022-02-25 | 浙江大学 | 基于双光子显微镜技术的溶栓药效评价方法 |
| KR20250095766A (ko) * | 2020-09-24 | 2025-06-26 | 큐리스 테크놀로지스 리미티드 | Ai-칩-온-칩, 임상 예측 엔진 |
| WO2022180595A1 (en) | 2021-02-26 | 2022-09-01 | Universidade Do Minho | Multiorgan-on-a-chip device with integrated microbiosensors, methods and uses thereof |
| EP4071234A1 (en) | 2021-04-06 | 2022-10-12 | Julius-Maximilians-Universität Würzburg | Decive for fabricating a perfusable three-dimensional tissue construct |
| CN113186162B (zh) * | 2021-04-19 | 2023-08-15 | 西安交通大学 | 一种结构仿生的三维活性类脑组织生物芯片 |
| WO2022260653A1 (en) * | 2021-06-08 | 2022-12-15 | Hewlett-Packard Development Company, L.P. | Interface device for digital microfluidics |
| TWI769861B (zh) * | 2021-06-15 | 2022-07-01 | 國立清華大學 | 三維細胞培養與藥物測試篩選的陣列平台 |
| CN114369532B (zh) * | 2021-12-31 | 2023-10-03 | 中国科学院苏州纳米技术与纳米仿生研究所 | 一种模拟滤过泡的微流控细胞培养装置及其应用 |
| US20250246259A1 (en) | 2022-03-30 | 2025-07-31 | Infinite D.O.O. | Method for predictive testing of agents to assess triggering and suppressing adverse outcomes and/or diseases |
| EP4289929A1 (en) * | 2022-06-06 | 2023-12-13 | Finnadvance Oy | Membrane structure for stimulating and sensing biological materials, and cell culture plate and microfluidic device both using the same |
| CN115322904B (zh) * | 2022-10-12 | 2023-01-31 | 成都诺医德医学检验实验室有限公司 | 一种模拟膀胱结构的类器官培养装置及其应用 |
| CN115671397B (zh) * | 2022-11-10 | 2023-10-13 | 上海大学 | 一种多肽和双生长因子梯度分布的含细胞骨软骨支架及其制备方法和应用 |
| DE102023122869B3 (de) * | 2023-08-25 | 2025-02-20 | Freistaat Bayern (Universität Augsburg) | Autonome mikrofluidische Zellkulturplattform |
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| JP2007537759A (ja) * | 2004-05-19 | 2007-12-27 | マサチューセッツ・インスティテュート・オブ・テクノロジー | 灌流三次元細胞/組織疾患モデル |
| JP4812271B2 (ja) * | 2004-08-30 | 2011-11-09 | 一般社団法人オンチップ・セロミクス・コンソーシアム | 心筋拍動細胞を用いた細胞バイオアッセイチップおよびこれを用いるバイオアッセイ |
| RU45733U1 (ru) * | 2004-11-23 | 2005-05-27 | Давыдов Владимир Николаевич | Установка для осуществления микробиологических процессов |
| US7344739B2 (en) * | 2004-12-28 | 2008-03-18 | Council Of Scientific And Industrial Research | Anti-allergic herbal formulation |
| DE102006030068A1 (de) * | 2006-06-28 | 2008-01-03 | M2P-Labs Gmbh | Vorrichtung und Verfahren zur Zu- und Abfuhr von Fluiden in geschüttelten Mikroreaktoren Arrays |
| EP2069068A2 (en) * | 2006-09-28 | 2009-06-17 | The University of Washington | 3d micro-scale engineered tissue model systems |
| WO2008147428A1 (en) * | 2006-10-05 | 2008-12-04 | Nanopoint, Inc. | Systems and methods for active microfluidic cell handling |
| JP5602718B2 (ja) * | 2008-04-08 | 2014-10-08 | マサチューセッツ インスティテュート オブ テクノロジー | 三次元マイクロ流体プラットホームおよびその使用方法 |
-
2009
- 2009-06-04 CN CN200980120885.6A patent/CN102257124B/zh active Active
- 2009-06-04 WO PCT/EP2009/004008 patent/WO2009146911A2/en not_active Ceased
- 2009-06-04 US US12/996,015 patent/US20110086382A1/en not_active Abandoned
- 2009-06-04 EP EP14152941.2A patent/EP2730645A3/en not_active Withdrawn
- 2009-06-04 EP EP14152939.6A patent/EP2730644A3/en not_active Withdrawn
- 2009-06-04 EP EP09757294.5A patent/EP2335370B1/en active Active
- 2009-06-04 AU AU2009254177A patent/AU2009254177B2/en active Active
- 2009-06-04 SG SG2013064787A patent/SG193829A1/en unknown
- 2009-06-04 DK DK09757294.5T patent/DK2335370T3/da active
- 2009-06-04 JP JP2011512022A patent/JP5774477B2/ja active Active
- 2009-06-04 RU RU2010154493/14A patent/RU2517046C2/ru active
- 2009-06-04 CA CA2727003A patent/CA2727003C/en active Active
-
2014
- 2014-06-20 US US14/309,905 patent/US20140302549A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009146911A2 (en) | 2009-12-10 |
| AU2009254177A1 (en) | 2009-12-10 |
| HK1159157A1 (en) | 2012-07-27 |
| EP2730644A3 (en) | 2014-10-22 |
| SG193829A1 (en) | 2013-10-30 |
| EP2335370B1 (en) | 2014-03-19 |
| EP2730645A3 (en) | 2014-10-22 |
| AU2009254177B2 (en) | 2014-09-11 |
| RU2517046C2 (ru) | 2014-05-27 |
| EP2730644A2 (en) | 2014-05-14 |
| RU2010154493A (ru) | 2012-07-20 |
| CN102257124B (zh) | 2014-12-03 |
| EP2730645A2 (en) | 2014-05-14 |
| CA2727003A1 (en) | 2009-12-10 |
| CA2727003C (en) | 2018-09-18 |
| JP2011528653A (ja) | 2011-11-24 |
| US20110086382A1 (en) | 2011-04-14 |
| WO2009146911A3 (en) | 2011-09-15 |
| CN102257124A (zh) | 2011-11-23 |
| JP5774477B2 (ja) | 2015-09-09 |
| US20140302549A1 (en) | 2014-10-09 |
| EP2335370A2 (en) | 2011-06-22 |
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