DK2155347T3 - Fremgangsmåde og apparat til kontinuerlig membranadsorption - Google Patents
Fremgangsmåde og apparat til kontinuerlig membranadsorptionInfo
- Publication number
- DK2155347T3 DK2155347T3 DK07747285T DK07747285T DK2155347T3 DK 2155347 T3 DK2155347 T3 DK 2155347T3 DK 07747285 T DK07747285 T DK 07747285T DK 07747285 T DK07747285 T DK 07747285T DK 2155347 T3 DK2155347 T3 DK 2155347T3
- Authority
- DK
- Denmark
- Prior art keywords
- continuous membrane
- membrane adsorption
- adsorption
- continuous
- membrane
- Prior art date
Links
- 239000012528 membrane Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000001179 sorption measurement Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1807—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using counter-currents, e.g. fluidised beds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1814—Recycling of the fraction to be distributed
- B01D15/1821—Simulated moving beds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/50—Conditioning of the sorbent material or stationary liquid
- G01N30/52—Physical parameters
- G01N2030/524—Physical parameters structural properties
- G01N2030/527—Physical parameters structural properties sorbent material in form of a membrane
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/468—Flow patterns using more than one column involving switching between different column configurations
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Sustainable Development (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/NL2007/000103 WO2008127087A1 (en) | 2007-04-17 | 2007-04-17 | Method and device for continuous membrane adsorption |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2155347T3 true DK2155347T3 (da) | 2013-10-21 |
Family
ID=38846979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07747285T DK2155347T3 (da) | 2007-04-17 | 2007-04-17 | Fremgangsmåde og apparat til kontinuerlig membranadsorption |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9012212B2 (da) |
| EP (1) | EP2155347B1 (da) |
| JP (1) | JP5140721B2 (da) |
| CN (1) | CN101678244B (da) |
| AU (1) | AU2007351639B2 (da) |
| DK (1) | DK2155347T3 (da) |
| WO (1) | WO2008127087A1 (da) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1775001A1 (en) | 2005-10-13 | 2007-04-18 | Xendo Holding B.V. | Device for chromatographic separations |
| US9527010B2 (en) * | 2009-09-25 | 2016-12-27 | Ge Healthcare Bio-Sciences Corp. | Separation system and method |
| CN102190704B (zh) * | 2010-03-17 | 2014-04-02 | 中国科学院过程工程研究所 | 蛋白层析系统 |
| CN105107228B (zh) | 2010-12-06 | 2017-03-29 | 颇尔公司 | 生物制品的连续加工方法 |
| DE102012112242C5 (de) * | 2012-12-13 | 2021-07-29 | Labor Berlin - Charité Vivantes GmbH | Analyseverfahren für die Analyse von Substanzgemischen |
| MX369522B (es) | 2013-02-22 | 2019-11-11 | Genzyme Corp | Metodos de cultivo por perfusión con microportadores y usos de los mismos. |
| SG11201506343QA (en) | 2013-02-22 | 2015-09-29 | Genzyme Corp | Microcarrier perfusion culturing methods and uses thereof |
| RU2768003C2 (ru) * | 2013-03-08 | 2022-03-22 | Джензим Корпорейшн | Интегрированное непрерывное производство терапевтических белковых лекарственных веществ |
| US10099156B2 (en) | 2013-04-08 | 2018-10-16 | Chromacon Ag | Chromatographic purification method |
| US10948483B2 (en) | 2013-04-08 | 2021-03-16 | Chromacon Ag | Method for control, monitoring and/or optimization of a chromatographic process |
| JP6203557B2 (ja) | 2013-07-05 | 2017-09-27 | 株式会社日立製作所 | 分離装置及び分離方法 |
| TWI709570B (zh) | 2014-01-17 | 2020-11-11 | 美商健臻公司 | 無菌層析法及製法 |
| TWI709569B (zh) | 2014-01-17 | 2020-11-11 | 美商健臻公司 | 無菌層析樹脂及其用於製造方法的用途 |
| GB201401010D0 (en) | 2014-01-21 | 2014-03-05 | Nat Nuclear Lab Ltd | Improved separation apparatus and method |
| TW202204596A (zh) | 2014-06-06 | 2022-02-01 | 美商健臻公司 | 灌注培養方法及其用途 |
| TWI776235B (zh) | 2014-06-09 | 2022-09-01 | 美商健臻公司 | 種子罐培養法(seed train processes)及其用途 |
| WO2016107809A1 (en) | 2014-12-31 | 2016-07-07 | Ge Healthcare Bio-Sciences Ab | Valve manifolds for simulated moving bed chromatography |
| EP3381529A1 (fr) | 2017-03-29 | 2018-10-03 | EMD Millipore Corporation | Installation de traitement de liquide biologique |
| EP3381530A1 (fr) | 2017-03-29 | 2018-10-03 | EMD Millipore Corporation | Installation de traitement de liquide biologique |
| JP6790963B2 (ja) * | 2017-03-30 | 2020-11-25 | 株式会社島津製作所 | 液体クロマトグラフ |
| GB201715399D0 (en) * | 2017-09-22 | 2017-11-08 | Ge Healthcare Bio Sciences Ab | Valve unit for a chromatography apparatus |
| EP3773968B1 (en) * | 2018-03-29 | 2025-02-26 | Waters Technologies Corporation | Automated two-column recycling chromatography method for unlocking challenging separation problems |
| HK40046210A (en) | 2018-08-31 | 2021-10-29 | Genzyme Corporation | Sterile chromatography resin and use thereof in manufacturing processes |
| DE102018009597A1 (de) * | 2018-12-07 | 2020-06-10 | Sartorius Stedim Biotech Gmbh | Vorrichtung und Verfahren zur mehrfachen Änderung der Zusammensetzung eines Fluids |
| US20220135619A1 (en) * | 2019-02-24 | 2022-05-05 | Bristol-Myers Squibb Company | Methods of isolating a protein |
| GB201902743D0 (en) * | 2019-02-28 | 2019-04-17 | Ge Healthcare Bio Sciences Ab | Improvements in and relating to optimizing the operation of a chromatography system |
| GB201904522D0 (en) * | 2019-04-01 | 2019-05-15 | Puridify Ltd | A chromatography system |
| DE102020103925A1 (de) * | 2020-02-14 | 2021-08-19 | Sartorius Stedim Biotech Gmbh | Einweg-Vorrichtung zur Separation oder Aufreinigung eines großen Volumens eines Stoffgemischs |
| EP3991820A1 (en) * | 2020-11-03 | 2022-05-04 | Sartorius Stedim Biotech GmbH | System for membrane chromatography |
| DE102021116377A1 (de) | 2021-06-24 | 2022-12-29 | Fresenius Medical Care Deutschland Gmbh | Filtersystem, Steuerungsvorrichtung und Platine für dasselbe sowie Verfahren zum Wechsel |
| US12018765B2 (en) * | 2022-05-06 | 2024-06-25 | Sartorius Stedim Chromatography Systems Ltd. | Valve setup for SMB chromatography |
| US11879561B2 (en) * | 2022-05-20 | 2024-01-23 | Sartorius Stedim Chromatography Systems Ltd. | Valve setup for SMB chromatography |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4533398A (en) * | 1981-10-02 | 1985-08-06 | Uop Inc. | Extraction of sucrose |
| US5156736A (en) * | 1991-05-07 | 1992-10-20 | Schoenrock Karlheinz W R | Simulated moving bed apparatus using a single sorbent bed for separating components from a fluid stream |
| DE19629208A1 (de) * | 1995-01-20 | 1998-01-22 | Merck Patent Gmbh | Verwendung von modifizierten Membranen für "Simulated Moving Bed" Trennverfahren |
| WO1998003242A1 (de) | 1996-07-19 | 1998-01-29 | Merck Patent Gmbh | Verwendung nicht-partikulärer sorbentien für 'simulated moving bed' trennverfahren |
| DE19711173A1 (de) * | 1997-03-18 | 1998-09-24 | Sartorius Gmbh | Verfahren und Anlage für die adsorptive Stofftrennung |
| DE69834185T2 (de) | 1997-05-20 | 2007-01-25 | Zymequest, Inc., Beverly | Optische Sensoren für Zellbehandlungssysteme |
| AU2358101A (en) * | 1999-11-20 | 2001-06-04 | Scinu Tec Gmbh | Method for separating cells and biomolecules using counter-current chromatography |
| US6284883B1 (en) * | 2000-12-19 | 2001-09-04 | Lucent Technologies Inc. | DNA affinity chromatography |
| JP3868267B2 (ja) * | 2001-10-31 | 2007-01-17 | 株式会社荏原製作所 | マルチカラム・アフィニティー検出システム |
| SI1545574T1 (sl) * | 2002-09-13 | 2014-10-30 | Biogen Idec Inc. | Postopek za čiščenje polipeptidov s simulirano "moving bed" kromatografijo |
| JP2008514724A (ja) | 2004-10-01 | 2008-05-08 | スリーエム イノベイティブ プロパティズ カンパニー | 液体混合物から標的分子を分離するための方法および装置 |
| EP1716900A1 (en) * | 2005-04-29 | 2006-11-02 | Eidgenössische Technische Hochschule Zürich | Method and device for chromatographic purification |
| EP1775001A1 (en) * | 2005-10-13 | 2007-04-18 | Xendo Holding B.V. | Device for chromatographic separations |
| US8920645B2 (en) * | 2005-12-07 | 2014-12-30 | Tarpon Biosystems Inc. | Disposable chromatography valves and system |
| GB0606144D0 (en) | 2006-03-28 | 2006-05-10 | Ge Healthcare Bio Sciences Ab | Automated crossflow filtration method and system |
-
2007
- 2007-04-17 CN CN2007800533894A patent/CN101678244B/zh active Active
- 2007-04-17 JP JP2010503994A patent/JP5140721B2/ja active Active
- 2007-04-17 WO PCT/NL2007/000103 patent/WO2008127087A1/en not_active Ceased
- 2007-04-17 AU AU2007351639A patent/AU2007351639B2/en active Active
- 2007-04-17 DK DK07747285T patent/DK2155347T3/da active
- 2007-04-17 US US12/596,390 patent/US9012212B2/en active Active
- 2007-04-17 EP EP20070747285 patent/EP2155347B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008127087A1 (en) | 2008-10-23 |
| JP5140721B2 (ja) | 2013-02-13 |
| CN101678244A (zh) | 2010-03-24 |
| CN101678244B (zh) | 2013-06-19 |
| AU2007351639A1 (en) | 2008-10-23 |
| EP2155347A1 (en) | 2010-02-24 |
| AU2007351639B2 (en) | 2012-12-13 |
| JP2010525318A (ja) | 2010-07-22 |
| EP2155347B1 (en) | 2013-07-17 |
| US9012212B2 (en) | 2015-04-21 |
| US20100144028A1 (en) | 2010-06-10 |
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