[go: up one dir, main page]

DK2155185T3 - Påvisning af succinylacetone - Google Patents

Påvisning af succinylacetone

Info

Publication number
DK2155185T3
DK2155185T3 DK08755064.6T DK08755064T DK2155185T3 DK 2155185 T3 DK2155185 T3 DK 2155185T3 DK 08755064 T DK08755064 T DK 08755064T DK 2155185 T3 DK2155185 T3 DK 2155185T3
Authority
DK
Denmark
Prior art keywords
succinylacetone
sample
mass spectrometry
hydrazine
detection
Prior art date
Application number
DK08755064.6T
Other languages
English (en)
Other versions
DK2155185T4 (da
Inventor
Marca Giancarlo La
Alex Cherkasskiy
Blas Cerda
Yijun Li
Original Assignee
Azienda Ospedaliero Universitaria Meyer Di Firenze
Perkinelmer Health Sci Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39939802&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2155185(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Azienda Ospedaliero Universitaria Meyer Di Firenze, Perkinelmer Health Sci Inc filed Critical Azienda Ospedaliero Universitaria Meyer Di Firenze
Application granted granted Critical
Publication of DK2155185T3 publication Critical patent/DK2155185T3/da
Publication of DK2155185T4 publication Critical patent/DK2155185T4/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/64Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving ketones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/04Endocrine or metabolic disorders
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555Hetero-N
    • Y10T436/147777Plural nitrogen in the same ring [e.g., barbituates, creatinine, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/20Oxygen containing
    • Y10T436/200833Carbonyl, ether, aldehyde or ketone containing
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/20Oxygen containing
    • Y10T436/200833Carbonyl, ether, aldehyde or ketone containing
    • Y10T436/201666Carboxylic acid
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/24Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2525Stabilizing or preserving
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Luminescent Compositions (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK08755064.6T 2007-05-04 2008-05-05 Påvisning af succinylacetone DK2155185T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/744,789 US7951608B2 (en) 2007-05-04 2007-05-04 Detecting succinylacetone
PCT/US2008/062694 WO2008137868A1 (en) 2007-05-04 2008-05-05 Detecting succinylacetone

Publications (2)

Publication Number Publication Date
DK2155185T3 true DK2155185T3 (da) 2012-07-16
DK2155185T4 DK2155185T4 (da) 2022-02-07

Family

ID=39939802

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08755064.6T DK2155185T4 (da) 2007-05-04 2008-05-05 Påvisning af succinylacetone

Country Status (10)

Country Link
US (3) US7951608B2 (da)
EP (1) EP2155185B2 (da)
CN (1) CN101742995B (da)
AT (1) ATE551055T1 (da)
AU (1) AU2008247428C1 (da)
BR (2) BR122019018448B8 (da)
CA (1) CA2686202C (da)
DK (1) DK2155185T4 (da)
ES (1) ES2384288T5 (da)
WO (1) WO2008137868A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100227412A1 (en) * 2009-02-06 2010-09-09 Perkinelmer Health Sciences, Inc. Simultaneous Detection of Estrogen and Non Estrogen Steroids
GB201215924D0 (en) * 2012-09-06 2012-10-24 Univ Swansea Kit and method for quantitative detection of steroids
CN104797938B (zh) * 2012-12-03 2017-12-26 国家血清研究所 在新生儿的筛查中诊断半乳糖血症的方法
WO2015059065A1 (en) 2013-10-22 2015-04-30 Roche Diagnostics Gmbh Methods for measuring cell-free virus particles from dried blood spots
CN105572233A (zh) * 2014-11-18 2016-05-11 湖南农业大学 植物叶片中琥珀酰丙酮的检测方法
WO2018174858A1 (en) * 2017-03-21 2018-09-27 Mprobe Inc. Clinical method for the population screening of adult metabolic disorder associated with chronic human disease
CN108008031A (zh) * 2017-11-17 2018-05-08 深圳华大生命科学研究院 同时检测氨基酸、肉碱、酮类、激素的方法和试剂盒
CN108051494A (zh) * 2017-11-17 2018-05-18 深圳华大生命科学研究院 一种同时检测多种遗传代谢疾病相关物质的方法和试剂盒
CN110568088A (zh) * 2019-05-22 2019-12-13 广州金域医学检验中心有限公司 琥珀酰丙酮的检测方法
CN116829922A (zh) * 2020-12-17 2023-09-29 豪夫迈·罗氏有限公司 用于质谱法的基于蒸发的样品制备工作流程
CN113030326B (zh) * 2021-03-12 2023-03-10 杭州度安医学检验实验室有限公司 一种用于分离柠檬酸和异柠檬酸的衍生试剂盒和方法
US20220395767A1 (en) * 2021-06-15 2022-12-15 Perkinelmer Health Sciences, Inc. Enhancing lcms analyte signals
CN114965786B (zh) * 2022-06-07 2023-11-03 重庆医科大学附属儿童医院 一种检测干血斑中酯类胆固醇多种中间代谢产物的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040219685A1 (en) 2003-01-30 2004-11-04 Applera Corporation Methods and mixtures pertaining to analyte determination using electrophilic labeling reagents
CA2543315A1 (en) 2003-11-13 2005-06-02 The General Hospital Corporation Methods for treating pain
US20070004045A1 (en) 2005-06-07 2007-01-04 Xia Xu Analysis of large numbers of estrogens and other steroids and applications thereof

Also Published As

Publication number Publication date
ATE551055T1 (de) 2012-04-15
BRPI0811536A2 (pt) 2014-11-18
CA2686202A1 (en) 2008-11-13
US8278116B2 (en) 2012-10-02
AU2008247428A1 (en) 2008-11-13
EP2155185B2 (en) 2021-12-01
EP2155185B1 (en) 2012-03-28
CA2686202C (en) 2017-07-04
ES2384288T5 (es) 2022-05-26
CN101742995B (zh) 2013-08-14
BRPI0811536B1 (pt) 2020-08-11
US20080274563A1 (en) 2008-11-06
US8513025B2 (en) 2013-08-20
EP2155185A4 (en) 2010-11-24
AU2008247428C1 (en) 2015-01-29
ES2384288T3 (es) 2012-07-03
US20120309096A1 (en) 2012-12-06
EP2155185A1 (en) 2010-02-24
BRPI0811536B8 (pt) 2021-07-27
BR122019018448B1 (pt) 2020-06-30
DK2155185T4 (da) 2022-02-07
BR122019018448B8 (pt) 2021-07-27
US20110201539A1 (en) 2011-08-18
US7951608B2 (en) 2011-05-31
AU2008247428B2 (en) 2014-07-03
BRPI0811536A8 (pt) 2019-10-15
WO2008137868A1 (en) 2008-11-13
CN101742995A (zh) 2010-06-16

Similar Documents

Publication Publication Date Title
DK2155185T4 (da) Påvisning af succinylacetone
EP1962085A3 (en) Apparatus for emitting and detecting beams of light
DK2132339T3 (da) Fremgangsmåde til detektering af en analyt i en biologisk matrix
MX2020002799A (es) Dispositivo de ensayo biologico multiplexado con lectura electronica.
MX2017011312A (es) Metodos para la cuantificacion de los niveles de insulina por espectrometria de masas.
GB2474146A (en) Methods of determining the health status of an individual
EP4414690A3 (en) Biosensors for biological or chemical analysis and methods of manufacturing the same
SE0800724L (sv) Blodviskositetsanalys
EA201101563A1 (ru) Безколбовый спектрометр
ECSP088081A (es) Detección de un antigeno diana independientemente de la presencia o ausencia de un anticuerpo terapéutico correspondiente
UY29721A1 (es) Medidor con alarma de tiempo postprandial para efectuar determinaciones
EA201992748A1 (ru) Диагностические анализы для обнаружения, количественного определения и/или отслеживания микроорганизмов и других аналитов
WO2008070865A3 (en) Materials and methods for efficient and accurate detection of analytes
EP4361606A3 (en) Signal encoding and decoding in multiplexed biochemical assays
CY1112553T1 (el) Ανοσοπροσδιορισμοι υψηλης ευαισθησιας και κιτια για τον προσδιορισμο πεπτιδιων και πρωτεϊνων βιολογικου ενδιαφεροντος
WO2008106648A3 (en) Immunoassays exhibiting a reduction in prozone phenomena
WO2009103843A3 (en) Method and device for detection of an analyte
EP2583100A4 (en) ROTORS FOR IMMUNOASSAYS
ATE532063T1 (de) Elektrochemischer biosensor
EA201391627A1 (ru) Анализ на наличие лизилоксидазоподобных белков 2 и способы его применения
WO2009099905A3 (en) Molecular signatures and biomarkers associated with melanoma and methods of use thereof
DE602006011756D1 (de) Komplexformierungs- und -trennungsverfahren
MX2009010751A (es) Composiciones y metodos de deteccion.
WO2015077382A3 (en) Combined cytology and molecular testing for early detection of esophageal adenocarcinoma
WO2011088423A3 (en) Isobaric tags for analyte detection and quantification