DK2019872T3 - Fremgangsmåde til forudsigelse af modtageligheden over for TNF-blokkere - Google Patents
Fremgangsmåde til forudsigelse af modtageligheden over for TNF-blokkereInfo
- Publication number
- DK2019872T3 DK2019872T3 DK07789647.0T DK07789647T DK2019872T3 DK 2019872 T3 DK2019872 T3 DK 2019872T3 DK 07789647 T DK07789647 T DK 07789647T DK 2019872 T3 DK2019872 T3 DK 2019872T3
- Authority
- DK
- Denmark
- Prior art keywords
- predicting susceptibility
- tnf blockers
- genes
- patient
- tnf
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102100040605 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase Human genes 0.000 abstract 1
- 101710181757 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase Proteins 0.000 abstract 1
- 102100034036 39S ribosomal protein L22, mitochondrial Human genes 0.000 abstract 1
- 102100023679 40S ribosomal protein S28 Human genes 0.000 abstract 1
- 102100040084 A-kinase anchor protein 9 Human genes 0.000 abstract 1
- 238000000018 DNA microarray Methods 0.000 abstract 1
- 102100039369 Epidermal growth factor receptor substrate 15 Human genes 0.000 abstract 1
- 102100031618 HLA class II histocompatibility antigen, DP beta 1 chain Human genes 0.000 abstract 1
- 108010045483 HLA-DPB1 antigen Proteins 0.000 abstract 1
- 101000711436 Homo sapiens 39S ribosomal protein L22, mitochondrial Proteins 0.000 abstract 1
- 101000623076 Homo sapiens 40S ribosomal protein S28 Proteins 0.000 abstract 1
- 101000890598 Homo sapiens A-kinase anchor protein 9 Proteins 0.000 abstract 1
- 101000812517 Homo sapiens Epidermal growth factor receptor substrate 15 Proteins 0.000 abstract 1
- 101000870945 Homo sapiens Ras guanyl-releasing protein 3 Proteins 0.000 abstract 1
- -1 PTNP12 Proteins 0.000 abstract 1
- 102100033450 Ras guanyl-releasing protein 3 Human genes 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 239000002981 blocking agent Substances 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analyzing Materials Using Thermal Means (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06290789A EP1857559A1 (en) | 2006-05-16 | 2006-05-16 | A method for predicting responsiveness to TNF alpha blocking agents |
| PCT/IB2007/002373 WO2007135568A2 (en) | 2006-05-16 | 2007-05-15 | A METHOD FOR PREDICTING RESPONSIVENESS TO TNFα BLOCKING AGENTS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2019872T3 true DK2019872T3 (da) | 2012-01-16 |
Family
ID=36764554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07789647.0T DK2019872T3 (da) | 2006-05-16 | 2007-05-15 | Fremgangsmåde til forudsigelse af modtageligheden over for TNF-blokkere |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7985549B2 (da) |
| EP (2) | EP1857559A1 (da) |
| AT (1) | ATE530670T1 (da) |
| CA (1) | CA2652087A1 (da) |
| DK (1) | DK2019872T3 (da) |
| ES (1) | ES2375865T3 (da) |
| WO (1) | WO2007135568A2 (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG182183A1 (en) * | 2007-06-08 | 2012-07-30 | Biogen Idec Inc | Biomarkers for predicting anti-tnf responsiveness or non-responsiveness |
| US20110059445A1 (en) * | 2008-03-28 | 2011-03-10 | Paul Rutgeerts | Mucosal gene signatures |
| EP2288732B1 (en) * | 2008-06-12 | 2013-10-02 | INSERM (Institut National de la Santé et de la Recherche Médicale) | A method for predicting the response to a treatment with anakinra |
| ES2335381B1 (es) * | 2008-09-24 | 2011-02-28 | Fundacio Institut De Recerca De L'hospital Universitari Vall D'hebron | Metodo in vitro y kit para el pronostico o prediccion de la respuestapor parte de pacientes con artritis reumatoide al tratamiento con agentes bloqueantes del factor tnfalfa. |
| EP2192197A1 (en) * | 2008-11-27 | 2010-06-02 | Vereniging voor christelijk hoger onderwijs, wetenschappelijk onderzoek en patiëntenzorg | Predicting clinical response to treatment with a soluble tnf-antagonist or tnf, or a tnf receptor agonist |
| MX2012002766A (es) | 2009-09-03 | 2012-04-02 | Genentech Inc | Metodos para el tratamiento, diagnosis y monitoreo de artritis reumatoide. |
| EP2538973A2 (en) | 2010-02-26 | 2013-01-02 | Novo Nordisk A/S | Stable antibody containing compositions |
| WO2011117366A2 (en) * | 2010-03-24 | 2011-09-29 | Tc Land Expression | Genes and genes combinations predictive of early response or non response of subjects suffering from inflammatory disease to cytokine targeting drugs (cytd) |
| US20130136733A1 (en) | 2010-05-28 | 2013-05-30 | Novo Nordisk A/S | Stable Multi-Dose Compositions Comprising an Antibody and a Preservative |
| WO2012118750A2 (en) | 2011-02-28 | 2012-09-07 | Genentech, Inc. | Biological markers and methods for predicting response to b-cell antagonists |
| SG10201605516YA (en) * | 2011-07-06 | 2016-08-30 | Nestec Sa | Assays for detecting neutralizing autoantibodies to biologic therapy with tnf alpha |
| CN104204230A (zh) | 2012-02-10 | 2014-12-10 | 诺和诺德A/S（股份有限公司） | 治疗炎性疾病和病症的相关方法 |
| HU230680B1 (hu) * | 2012-10-19 | 2017-08-28 | Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag | Diagnosztikai eljárás |
| WO2014134570A1 (en) * | 2013-02-28 | 2014-09-04 | Nodality, Inc. | Compositions and methods for autoimmune disease |
| EP3884276A2 (en) * | 2018-11-23 | 2021-09-29 | Katholieke Universiteit Leuven | Predicting a treatment response in inflammatory bowel disease |
| JP2024527529A (ja) * | 2021-06-22 | 2024-07-25 | サイファー メディシン コーポレーション | 治療モニタリングおよび試験設計のための方法とシステム |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US196799A (en) | 1877-11-06 | Improvement in washing-machines | ||
| ATE537270T1 (de) * | 1997-10-30 | 2011-12-15 | Cold Spring Harbor Lab | Sondenanordnungen und deren verwendungen für verfahren zur dns-unterscheidung |
-
2006
- 2006-05-16 EP EP06290789A patent/EP1857559A1/en not_active Withdrawn
-
2007
- 2007-05-15 EP EP07789647A patent/EP2019872B1/en not_active Not-in-force
- 2007-05-15 ES ES07789647T patent/ES2375865T3/es active Active
- 2007-05-15 CA CA002652087A patent/CA2652087A1/en not_active Abandoned
- 2007-05-15 DK DK07789647.0T patent/DK2019872T3/da active
- 2007-05-15 AT AT07789647T patent/ATE530670T1/de active
- 2007-05-15 US US12/300,847 patent/US7985549B2/en not_active Expired - Fee Related
- 2007-05-15 WO PCT/IB2007/002373 patent/WO2007135568A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US7985549B2 (en) | 2011-07-26 |
| US20090252740A1 (en) | 2009-10-08 |
| EP2019872B1 (en) | 2011-10-26 |
| EP2019872A2 (en) | 2009-02-04 |
| WO2007135568A2 (en) | 2007-11-29 |
| ES2375865T3 (es) | 2012-03-07 |
| ATE530670T1 (de) | 2011-11-15 |
| EP1857559A1 (en) | 2007-11-21 |
| WO2007135568A3 (en) | 2008-02-28 |
| CA2652087A1 (en) | 2007-11-29 |
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