DK2074120T3 - Tropan-forbindelser - Google Patents

Tropan-forbindelser

Info

Publication number: DK2074120T3
Authority: DK; Denmark
Prior art keywords: tropane compounds; tropane; compounds; formula; methods
Prior art date: 2007-10-25

Application number

DK08832769.7T

Other languages

English (en)

Inventor

Kenneth D Rice

Naing Aay

Arlyn Arcalas

Tae-Gon Baik

Charles M Blazey

Owen Joseph Bowles

Chris A Buhr

Joerg Bussenius

Simona Costanzo

Jeffry Kimo Curtis

Steven Charles Defina

Larisa Dubenko

Abigail R Kennedy

Angie Inyoung Kim

Katherine Lara

Sunghoon Ma

Jean-Claire Limun Manalo

Csaba J Peto

Tsze H Tsang

Longcheng Wang

Neel Kumar Anand

Original Assignee

Exelixis Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-10-25

Filing date

2008-10-27

Publication date

2010-06-14

2008-10-27 Application filed by Exelixis Inc filed Critical Exelixis Inc

2010-06-14 Application granted granted Critical

2010-06-14 Publication of DK2074120T3 publication Critical patent/DK2074120T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Immunology (AREA)
Neurology (AREA)
Molecular Biology (AREA)
Rheumatology (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Hematology (AREA)
Cardiology (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Biotechnology (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Psychiatry (AREA)
Diabetes (AREA)
Obesity (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Transplantation (AREA)

DK08832769.7T 2007-10-25 2008-10-27 Tropan-forbindelser DK2074120T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US68707P	2007-10-25	2007-10-25
PCT/US2008/012221 WO2009055077A1 (en)	2007-10-25	2008-10-27	Tropane compounds

Publications (1)

Publication Number	Publication Date
DK2074120T3 true DK2074120T3 (da)	2010-06-14

Family

ID=40287869

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK08832769.7T DK2074120T3 (da)	2007-10-25	2008-10-27	Tropan-forbindelser

Country Status (26)

Country	Link
US (1)	US8012956B2 (da)
EP (1)	EP2074120B1 (da)
JP (2)	JP5476307B2 (da)
KR (1)	KR101578792B1 (da)
CN (1)	CN101910168B (da)
AT (1)	ATE459622T1 (da)
AU (1)	AU2008317262B2 (da)
BR (1)	BRPI0818893B8 (da)
CA (1)	CA2703477C (da)
CO (1)	CO6321232A2 (da)
CY (1)	CY1110648T1 (da)
DE (1)	DE602008000754D1 (da)
DK (1)	DK2074120T3 (da)
EA (1)	EA018999B1 (da)
ES (1)	ES2342348T3 (da)
HR (1)	HRP20100292T1 (da)
IL (1)	IL205202A0 (da)
MX (1)	MX2010004493A (da)
NZ (1)	NZ585137A (da)
PL (1)	PL2074120T3 (da)
PT (1)	PT2074120E (da)
RS (1)	RS51346B (da)
SG (1)	SG2012079653A (da)
SI (1)	SI2074120T1 (da)
WO (1)	WO2009055077A1 (da)
ZA (1)	ZA201002987B (da)

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US8129390B2 (en) *	2007-12-12	2012-03-06	Rigel Pharmaceuticals, Inc.	Carboxamide, sulfonamide and amine compounds and methods for using the same
FR2949467B1 (fr)	2009-09-03	2011-11-25	Sanofi Aventis	Nouveaux derives de 5,6,7,8-tetrahydroindolizine inhibiteurs d'hsp90, compositions les contenant et utilisation
UY32940A (es)	2009-10-27	2011-05-31	Bayer Cropscience Ag	Amidas sustituidas con halogenoalquilo como insecticidas y acaricidas
US9145425B2 (en)	2010-04-05	2015-09-29	Shionogi & Co., Ltd.	Cephem compound having catechol group
WO2012068096A2 (en)	2010-11-15	2012-05-24	Exelixis, Inc.	Benzoxazepines as inhibitors of pi3k/mtor and methods of their use and manufacture
EP2740474A1 (en)	2012-12-05	2014-06-11	Instituto Europeo di Oncologia S.r.l.	Cyclopropylamine derivatives useful as inhibitors of histone demethylases kdm1a
WO2014107718A2 (en) *	2013-01-07	2014-07-10	H. Lee Moffitt Cancer Center And Research Institute, Inc.	Heat shock protein (hsp) inhibition and monitoring effectiveness thereof
HK1225716A1 (zh)	2013-08-21	2017-09-15	Alios Biopharma, Inc.	抗病毒化合物
JP2016538574A (ja) *	2013-11-18	2016-12-08	デルマーファーマシューティカルズ	ジアンヒドロガラクチトール中の不純物のｈｐｌｃ分析
EP2949648A1 (en)	2014-05-30	2015-12-02	IEO - Istituto Europeo di Oncologia Srl	Cyclopropylamine derivatives as histone demethylase inhibitors
EP3148974B1 (en)	2014-05-30	2018-09-26	Istituto Europeo di Oncologia S.r.l.	Cyclopropylamine compounds as histone demethylase inhibitors
TW201625243A (zh)	2014-10-14	2016-07-16	艾克塞里克斯公司	用於治療黑素瘤之藥物組合
US20180200392A1 (en) *	2015-07-16	2018-07-19	Akuru Pharma Ab	Detection and treatment of renal cell carcinoma with a slc6a3 ligand linked to a label, cytotoxic or immunomodulatory group
EP3588064B1 (en) *	2017-02-23	2022-09-07	IHI Corporation	Oh radical detection probe, oh radical measurement device, and oh radical measurement method
CN108164529B (zh) *	2017-12-25	2020-04-24	三峡大学	一种小分子抑制剂sld9059及其在制药中的应用
DK3737677T3 (da)	2018-01-10	2022-01-10	Allinky Biopharma	Tetrahydroisoquinolinforbindelser
CN111825702A (zh) *	2019-04-22	2020-10-27	成都科岭源医药技术有限公司	一种氮杂*并吲唑类衍生物及其制备方法和用途
CN110698395B (zh) *	2019-10-22	2021-05-25	杭州百诚医药科技股份有限公司	一种托吡司特的中间体的制备方法
CN112920078A (zh) *	2019-12-05	2021-06-08	武汉珈汇精化科技有限公司	一种制备4-氰基苯甲酸甲酯的方法和一种制备4-氰基苯甲酸的方法
TW202136238A (zh) *	2020-01-06	2021-10-01	大陸商廣東東陽光藥業有限公司	RORγt抑制劑及其製備方法和用途
EP4229053A1 (en) *	2020-10-14	2023-08-23	Ranok Therapeutics (Hangzhou) Co. Ltd.	Methods and compositions for targeted protein degradation
CN114591192B (zh) *	2020-12-04	2024-06-21	江西仰立新材料有限公司	一种n-环丙甲基苯胺类化合物的制备方法
US20240083910A1 (en) *	2020-12-18	2024-03-14	Merck Sharp & Dohme Llc	Amido-substituted pyridyl compounds and methods of use thereof for the treatment of herpesviruses
CN112707809B (zh) *	2020-12-30	2023-08-29	丽珠集团新北江制药股份有限公司	一种制备噁唑啉杀虫剂氟雷拉纳中间体的方法
MX2024001265A (es) *	2021-07-26	2024-02-14	Zoetis Services Llc	Compuestos inhibidores de serotonina 5-ht2b.

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EP0101641A3 (en)	1982-07-22	1984-03-28	Beecham Group Plc	Sulfonylamino-aza-bicyclo-alkyl derivatives
FR2738569B1 (fr)	1995-09-12	1997-11-28	Pf Medicament	Nouveaux derives naphtamide de 3 beta-amino azabicyclo octane ou nonane, leur procede de preparation, leur utilisation a titre de medicament antipsychotique
JP4169368B2 (ja) *	1996-01-15	2008-10-22	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	脈管形成阻害性ピリダジンアミン
HUP0202001A2 (hu) *	2002-06-14	2005-08-29	Sanofi-Aventis	DDP-IV gátló hatású azabiciklooktán- és nonánszármazékok
US7358244B2 (en) *	2003-05-28	2008-04-15	Theravance, Inc.	Azabicycloalkane compounds
CA2530023A1 (en) *	2003-06-24	2004-12-29	Neurosearch A/S	Novel 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
GB0323236D0 (en) *	2003-10-03	2003-11-05	Pfizer Ltd	Chemical compounds
EP1682545B1 (en) *	2003-10-03	2007-12-12	Pfizer Limited	Imidazopyridine substituted tropane derivatives with ccr5 receptor antagonist activity for the treatment of hiv and inflammation
PT1731518E (pt) *	2004-03-31	2014-09-18	Nippon Soda Co	Composto amina cíclico e agente de controlo de pragas
FR2873693B1 (fr) *	2004-07-29	2006-09-15	Sanofi Synthelabo	Derives d'amino-tropane, leur preparation et leur application en therapeutique
US7713990B2 (en)	2005-01-13	2010-05-11	Neurosearch A/S	3,8-substituted 8-AZA-bicyclo[3.2.1]octane derivatives and their use as monomine neurotransmitter re-uptake inhibitors
EP2251341A1 (en) *	2005-07-14	2010-11-17	Astellas Pharma Inc.	Heterocyclic Janus kinase 3 inhibitors
WO2007040280A1 (ja) *	2005-10-06	2007-04-12	Nippon Soda Co., Ltd.	環状アミン化合物および有害生物防除剤
BRPI0716240B8 (pt) *	2006-09-01	2019-09-17	Oat Agrio Co Ltd	composto de n-piridilpiperidina, método para a sua produção, e agente de controle de pestes

2008
- 2008-10-27 US US12/290,159 patent/US8012956B2/en active Active
- 2008-10-27 EP EP08832769A patent/EP2074120B1/en active Active
- 2008-10-27 MX MX2010004493A patent/MX2010004493A/es active IP Right Grant
- 2008-10-27 SI SI200830024T patent/SI2074120T1/sl unknown
- 2008-10-27 CN CN200880122860.5A patent/CN101910168B/zh not_active Expired - Fee Related
- 2008-10-27 ES ES08832769T patent/ES2342348T3/es active Active
- 2008-10-27 PT PT08832769T patent/PT2074120E/pt unknown
- 2008-10-27 SG SG2012079653A patent/SG2012079653A/en unknown
- 2008-10-27 DK DK08832769.7T patent/DK2074120T3/da active
- 2008-10-27 RS RSP-2010/0220A patent/RS51346B/sr unknown
- 2008-10-27 AT AT08832769T patent/ATE459622T1/de active
- 2008-10-27 BR BRPI0818893A patent/BRPI0818893B8/pt not_active IP Right Cessation
- 2008-10-27 CA CA2703477A patent/CA2703477C/en active Active
- 2008-10-27 KR KR1020107011444A patent/KR101578792B1/ko not_active Expired - Fee Related
- 2008-10-27 EA EA201070519A patent/EA018999B1/ru not_active IP Right Cessation
- 2008-10-27 JP JP2010531069A patent/JP5476307B2/ja not_active Expired - Fee Related
- 2008-10-27 PL PL08832769T patent/PL2074120T3/pl unknown
- 2008-10-27 WO PCT/US2008/012221 patent/WO2009055077A1/en not_active Ceased
- 2008-10-27 NZ NZ585137A patent/NZ585137A/en not_active IP Right Cessation
- 2008-10-27 HR HR20100292T patent/HRP20100292T1/hr unknown
- 2008-10-27 AU AU2008317262A patent/AU2008317262B2/en not_active Ceased
- 2008-10-27 DE DE602008000754T patent/DE602008000754D1/de active Active
2010
- 2010-04-19 IL IL205202A patent/IL205202A0/en active IP Right Grant
- 2010-04-29 ZA ZA2010/02987A patent/ZA201002987B/en unknown
- 2010-05-24 CO CO10061824A patent/CO6321232A2/es not_active Application Discontinuation
- 2010-06-01 CY CY20101100483T patent/CY1110648T1/el unknown
2013
- 2013-12-13 JP JP2013257559A patent/JP5745021B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ES2342348T3 (es)	2010-07-05
PT2074120E (pt)	2010-06-15
KR20100090782A (ko)	2010-08-17
ATE459622T1 (de)	2010-03-15
BRPI0818893A2 (pt)	2015-05-05
ZA201002987B (en)	2011-02-23
IL205202A0 (en)	2010-12-30
JP2011500815A (ja)	2011-01-06
MX2010004493A (es)	2010-06-11
CO6321232A2 (es)	2011-09-20
US20090163471A1 (en)	2009-06-25
CA2703477C (en)	2016-10-11
SG2012079653A (en)	2014-05-29
WO2009055077A1 (en)	2009-04-30
SI2074120T1 (sl)	2010-06-30
HK1129390A1 (en)	2009-11-27
AU2008317262A1 (en)	2009-04-30
EA201070519A1 (ru)	2010-12-30
CN101910168B (zh)	2014-07-30
RS51346B (sr)	2011-02-28
CA2703477A1 (en)	2009-04-30
BRPI0818893B1 (pt)	2021-02-02
PL2074120T3 (pl)	2010-08-31
EA018999B1 (ru)	2013-12-30
NZ585137A (en)	2012-07-27
HRP20100292T1 (hr)	2010-06-30
US8012956B2 (en)	2011-09-06
CY1110648T1 (el)	2015-06-10
JP2014070077A (ja)	2014-04-21
DE602008000754D1 (de)	2010-04-15
AU2008317262B2 (en)	2013-12-19
JP5745021B2 (ja)	2015-07-08
JP5476307B2 (ja)	2014-04-23
EP2074120B1 (en)	2010-03-03
CN101910168A (zh)	2010-12-08
EP2074120A1 (en)	2009-07-01
BRPI0818893B8 (pt)	2021-05-25
KR101578792B1 (ko)	2015-12-21

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