DK2041121T3 - Enantioselektiv syntese af pyrrolidinsubstituerede flavoner - Google Patents
Enantioselektiv syntese af pyrrolidinsubstituerede flavonerInfo
- Publication number
- DK2041121T3 DK2041121T3 DK06766035.7T DK06766035T DK2041121T3 DK 2041121 T3 DK2041121 T3 DK 2041121T3 DK 06766035 T DK06766035 T DK 06766035T DK 2041121 T3 DK2041121 T3 DK 2041121T3
- Authority
- DK
- Denmark
- Prior art keywords
- pyrrolidine
- enantioselective synthesis
- substituted flavones
- flavones
- substituted
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- -1 pyrrolidine-substituted flavones Chemical class 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB2006/052294 WO2008007169A1 (en) | 2006-07-07 | 2006-07-07 | An enantioselective synthesis of pyrrolidine-substituted flavones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2041121T3 true DK2041121T3 (da) | 2011-11-14 |
Family
ID=37546592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06766035.7T DK2041121T3 (da) | 2006-07-07 | 2006-07-07 | Enantioselektiv syntese af pyrrolidinsubstituerede flavoner |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7951961B2 (da) |
| EP (1) | EP2041121B1 (da) |
| JP (1) | JP5006396B2 (da) |
| KR (1) | KR101285957B1 (da) |
| CN (1) | CN101484445B (da) |
| AR (1) | AR061964A1 (da) |
| AT (1) | ATE517892T1 (da) |
| AU (1) | AU2006346193C1 (da) |
| BR (1) | BRPI0621851A2 (da) |
| CA (1) | CA2658215C (da) |
| DK (1) | DK2041121T3 (da) |
| IL (1) | IL196298A0 (da) |
| MX (1) | MX2009000109A (da) |
| NZ (1) | NZ573841A (da) |
| PT (1) | PT2041121E (da) |
| TW (1) | TWI391388B (da) |
| WO (1) | WO2008007169A1 (da) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7884127B2 (en) | 2002-07-08 | 2011-02-08 | Pirimal Life Sciences Ltd. | Inhibitors of cyclin dependent kinases and their use |
| LV14179B (lv) * | 2008-12-03 | 2010-08-20 | Ivars Kalvins | 2,2'-ciklopropilidēn-bis-oksazolīnu reģenerēšana |
| TWI461194B (zh) | 2009-05-05 | 2014-11-21 | Piramal Entpr Ltd | 吡咯啶取代黃酮作為輻射致敏劑 |
| WO2012069972A1 (en) | 2010-11-19 | 2012-05-31 | Piramal Life Sciences Limited | A pharmaceutical combination for the treatment of breast cancer |
| KR101264012B1 (ko) * | 2010-12-31 | 2013-05-13 | 주식회사 코리아나화장품 | 플라바논 화합물 및 그 제조방법, 이로부터 제조된 화장료 조성물 |
| WO2012123889A1 (en) | 2011-03-14 | 2012-09-20 | Piramal Healthcare Limited | A synergistic pharmaceutical combination for the treatment of pancreatic cancer |
| WO2012176163A2 (en) | 2011-06-24 | 2012-12-27 | Piramal Enterprises Limited | Compounds for the treatment of cancers associated with human papillomavirus |
| US20140348950A1 (en) | 2012-01-13 | 2014-11-27 | Piramal Enterprises Limited | Pyrrolidine- substituted flavone derivatives for prevention or treatment of oral mucositis |
| EP2877461B1 (en) * | 2012-07-27 | 2018-05-09 | Emory University | Heterocyclic flavone derivatives, compositions, and methods related thereto |
| JP5988305B2 (ja) * | 2013-03-29 | 2016-09-07 | 国立大学法人山口大学 | 光学活性α−ブロモベンゾイル酢酸エステル類の製造方法 |
| TW202502325A (zh) | 2013-07-12 | 2025-01-16 | 印度商皮拉馬爾企業有限公司 | 治療黑色素瘤的藥物組合的用途 |
| CN104725279B (zh) * | 2015-02-12 | 2018-03-02 | 威海迪素制药有限公司 | 一种N‑Boc‑联苯丙氨酸衍生物的制备方法 |
| CA2980643C (en) * | 2015-05-12 | 2023-10-17 | E I Du Pont De Nemours And Company | Aryl substituted bicyclic compounds as herbicides |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5849733A (en) * | 1996-05-10 | 1998-12-15 | Bristol-Myers Squibb Co. | 2-thio or 2-oxo flavopiridol analogs |
| JP2003531899A (ja) * | 2000-05-03 | 2003-10-28 | エルジー ライフ サイエンス リミテッド | ３−ヒドロキシクロメン−４−オン構造を有するｃｄｋ阻害剤 |
| AU2001296961A1 (en) * | 2000-09-29 | 2002-04-08 | Bayer Pharmaceuticals Corporation | 17-beta-hydroxysteroid dehydrogenase-ii inhibitors |
| TWI331034B (en) * | 2002-07-08 | 2010-10-01 | Piramal Life Sciences Ltd | Inhibitors of cyclin-dependent kinases and their use |
| AU2006344987B8 (en) | 2006-06-21 | 2013-07-11 | Piramal Enterprises Limited | Enantiomerically pure flavone derivatives for the treatment of proliferative disorders and processes for their preparation |
-
2006
- 2006-07-07 CA CA2658215A patent/CA2658215C/en active Active
- 2006-07-07 US US12/307,645 patent/US7951961B2/en active Active
- 2006-07-07 WO PCT/IB2006/052294 patent/WO2008007169A1/en not_active Ceased
- 2006-07-07 PT PT06766035T patent/PT2041121E/pt unknown
- 2006-07-07 JP JP2009518985A patent/JP5006396B2/ja not_active Expired - Fee Related
- 2006-07-07 AT AT06766035T patent/ATE517892T1/de active
- 2006-07-07 CN CN200680055257.0A patent/CN101484445B/zh not_active Expired - Fee Related
- 2006-07-07 DK DK06766035.7T patent/DK2041121T3/da active
- 2006-07-07 NZ NZ573841A patent/NZ573841A/en not_active IP Right Cessation
- 2006-07-07 MX MX2009000109A patent/MX2009000109A/es active IP Right Grant
- 2006-07-07 AU AU2006346193A patent/AU2006346193C1/en not_active Ceased
- 2006-07-07 EP EP06766035A patent/EP2041121B1/en not_active Not-in-force
- 2006-07-07 KR KR1020097002349A patent/KR101285957B1/ko not_active Expired - Fee Related
- 2006-07-07 BR BRPI0621851-2A patent/BRPI0621851A2/pt not_active IP Right Cessation
-
2007
- 2007-06-22 TW TW096122651A patent/TWI391388B/zh not_active IP Right Cessation
- 2007-07-06 AR ARP070103023A patent/AR061964A1/es not_active Application Discontinuation
-
2008
- 2008-12-31 IL IL196298A patent/IL196298A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009542796A (ja) | 2009-12-03 |
| WO2008007169A1 (en) | 2008-01-17 |
| CN101484445B (zh) | 2012-09-05 |
| AU2006346193C1 (en) | 2014-02-20 |
| US20100113803A1 (en) | 2010-05-06 |
| BRPI0621851A2 (pt) | 2013-01-29 |
| NZ573841A (en) | 2011-11-25 |
| EP2041121B1 (en) | 2011-07-27 |
| CA2658215C (en) | 2013-08-27 |
| MX2009000109A (es) | 2009-03-16 |
| IL196298A0 (en) | 2009-09-22 |
| US7951961B2 (en) | 2011-05-31 |
| JP5006396B2 (ja) | 2012-08-22 |
| AU2006346193A1 (en) | 2008-01-17 |
| AU2006346193B2 (en) | 2012-11-15 |
| KR101285957B1 (ko) | 2013-07-12 |
| EP2041121A1 (en) | 2009-04-01 |
| PT2041121E (pt) | 2011-09-12 |
| HK1126762A1 (en) | 2009-09-11 |
| CA2658215A1 (en) | 2008-01-17 |
| TW200815413A (en) | 2008-04-01 |
| TWI391388B (zh) | 2013-04-01 |
| CN101484445A (zh) | 2009-07-15 |
| KR20090033465A (ko) | 2009-04-03 |
| AR061964A1 (es) | 2008-08-10 |
| ATE517892T1 (de) | 2011-08-15 |
| AU2006346193A2 (en) | 2009-02-12 |
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