DK1974017T3 - Midler og fremgangsmåder til at påvirke stabiliteten af antistof producerende celler - Google Patents
Midler og fremgangsmåder til at påvirke stabiliteten af antistof producerende cellerInfo
- Publication number
- DK1974017T3 DK1974017T3 DK06824300T DK06824300T DK1974017T3 DK 1974017 T3 DK1974017 T3 DK 1974017T3 DK 06824300 T DK06824300 T DK 06824300T DK 06824300 T DK06824300 T DK 06824300T DK 1974017 T3 DK1974017 T3 DK 1974017T3
- Authority
- DK
- Denmark
- Prior art keywords
- affecting
- stability
- methods
- producing cells
- antibody producing
- Prior art date
Links
- 210000000628 antibody-producing cell Anatomy 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0635—B lymphocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/231—Interleukin-10 (IL-10)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2321—Interleukin-21 (IL-21)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/52—CD40, CD40-ligand (CD154)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/99—Coculture with; Conditioned medium produced by genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/04—Immortalised cells
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/NL2005/000848 WO2007067032A1 (en) | 2005-12-09 | 2005-12-09 | Means and methods for influencing the stability of cells |
| EP06076211 | 2006-06-12 | ||
| PCT/NL2006/000625 WO2007067046A1 (en) | 2005-12-09 | 2006-12-08 | Means and methods for influencing the stability of antibody producing cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK1974017T3 true DK1974017T3 (da) | 2014-02-10 |
| DK1974017T4 DK1974017T4 (da) | 2023-09-25 |
Family
ID=37714656
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK12175198.6T DK2540820T3 (da) | 2005-12-09 | 2006-12-08 | Midler og fremgangsmåder til påvirkning af stabiliteten af antistofproducerende celler |
| DK06824300.5T DK1974017T4 (da) | 2005-12-09 | 2006-12-08 | Midler og fremgangsmåder til at påvirke stabiliteten af antistof producerende celler |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK12175198.6T DK2540820T3 (da) | 2005-12-09 | 2006-12-08 | Midler og fremgangsmåder til påvirkning af stabiliteten af antistofproducerende celler |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US9127251B2 (da) |
| EP (3) | EP1974017B2 (da) |
| JP (2) | JP5753339B2 (da) |
| AU (2) | AU2006323315B2 (da) |
| BR (2) | BR122021001906B1 (da) |
| CA (2) | CA2633157C (da) |
| DK (2) | DK2540820T3 (da) |
| ES (2) | ES2444465T5 (da) |
| FI (1) | FI1974017T4 (da) |
| HU (1) | HUE037580T2 (da) |
| NZ (3) | NZ600075A (da) |
| PL (2) | PL2540820T3 (da) |
| PT (2) | PT2540820T (da) |
| WO (1) | WO2007067046A1 (da) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9127251B2 (en) | 2005-12-09 | 2015-09-08 | Academisch Medisch Centrum Bij De Universiteit Van Amsterdam | Means and methods for influencing the stability of antibody producing cells |
| WO2007067032A1 (en) | 2005-12-09 | 2007-06-14 | Academisch Medisch Cemtrum Bij De Universiteit Van Amsterdam | Means and methods for influencing the stability of cells |
| JP5205597B2 (ja) * | 2007-06-01 | 2013-06-05 | 静岡県 | 1細胞レベルでの抗体遺伝子の解析・同定方法 |
| EP1997830A1 (en) | 2007-06-01 | 2008-12-03 | AIMM Therapeutics B.V. | RSV specific binding molecules and means for producing them |
| EP2185718B1 (en) * | 2007-08-03 | 2017-10-04 | MUSC Foundation For Research Development | Human monoclonal antibodies and methods for producing the same |
| EP2307453A1 (en) * | 2008-06-16 | 2011-04-13 | University Of Zurich | Method of providing immunoglobulin secreting b lymphocytes and human antibodies |
| WO2010130636A1 (en) | 2009-05-11 | 2010-11-18 | Crucell Holland B.V. | Human binding molecules capable of neutralizing influenza virus h3n2 and uses thereof |
| EP2454283B1 (en) | 2009-07-15 | 2018-03-14 | AIMM Therapeutics B.V. | Means and methods for producing high affinity antibodies |
| US8568726B2 (en) | 2009-10-06 | 2013-10-29 | Medimmune Limited | RSV specific binding molecule |
| CN102770529B (zh) | 2009-11-17 | 2018-06-05 | Musc研究发展基金会 | 针对人核仁素的人单克隆抗体 |
| SI2400298T1 (sl) * | 2010-05-28 | 2013-11-29 | F. Hoffmann-La Roche Ag | Postopek kultivacije posamezne B-celice in izdelava specifičnih protiteles |
| ES2626671T3 (es) | 2010-12-02 | 2017-07-25 | Aimm Therapeutics B.V. | Medios y métodos para producir anticuerpos de alta afinidad |
| SG11201402780UA (en) | 2011-12-02 | 2014-10-30 | Aimm Therapeutics Bv | Influenza a virus specific antibodies |
| US10017739B2 (en) * | 2012-09-06 | 2018-07-10 | Duke University | Methods of expanding and assessing B cells and using expanded B cells to treat disease |
| DK2971039T3 (da) | 2013-03-14 | 2020-04-06 | Immusoft Corp | Fremgangsmåder til in vitro-differentiering af hukommelses-b-celler og transduktion med vsv-g-pseudotypeomdannede virusvektorer |
| CN106062002B (zh) | 2013-12-17 | 2021-05-04 | 埃姆医疗有限公司 | 抵抗骨髓增生障碍或淋巴组织增生障碍的手段和方法 |
| DK3087177T3 (da) * | 2013-12-24 | 2022-10-03 | Kling Biotherapeutics B V | Antistofproduktion ex vivo |
| DK3099709T3 (da) | 2014-01-31 | 2020-02-03 | Aimm Therapeutics Bv | Midler og fremgangsmåder til fremstilling af stabile antistoffer |
| CA2953277A1 (en) * | 2014-06-05 | 2015-12-10 | Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis | Means and methods for determining t cell recognition |
| US10428304B2 (en) | 2014-07-02 | 2019-10-01 | Tokyo University Of Science Foundation | Method for producing B cell population |
| US20180002664A1 (en) * | 2014-12-19 | 2018-01-04 | Immusoft Corporation | B cells for in vivo delivery of therapeutic agents |
| US20180094243A1 (en) * | 2015-04-03 | 2018-04-05 | Dana-Farber Cancer Institute, Inc. | Composition and methods of genome editing of b-cells |
| EP3307070B1 (en) * | 2015-06-12 | 2025-10-29 | Emory University | Growth and survival compositions for cells capable of producing antibodies and methods related thereto |
| EP3313870B1 (en) | 2015-06-24 | 2020-06-03 | Aimm Therapeutics B.V. | Aml antigens and uses thereof |
| SG11201805649UA (en) | 2016-01-08 | 2018-07-30 | Aimm Therapeutics Bv | Therapeutic anti-cd9 antibody |
| AU2017367695A1 (en) | 2016-12-02 | 2019-06-13 | Juno Therapeutics, Inc. | Engineered B cells and related compositions and methods |
| EP3576758A4 (en) | 2017-01-31 | 2020-12-09 | Vanderbilt University | GENERATION OF IGE MONOCLONAL ANTIBODIES SPECIFIC TO HUMAN ALLERGENS AND HELMINTHS FOR DIAGNOSTIC AND THERAPEUTIC USE |
| US11125757B2 (en) | 2017-05-26 | 2021-09-21 | Emory University | Methods of culturing and characterizing antibody secreting cells |
| WO2019113125A1 (en) * | 2017-12-05 | 2019-06-13 | Sqz Biotechnologies Company | Intracellular delivery of biomolecules to modulate antibody production |
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| US4997764A (en) * | 1987-04-23 | 1991-03-05 | New York University | Transformation of human B-lympocytes with Epstein Barr virus and c-myc containing vectors |
| ATE132190T1 (de) | 1988-02-26 | 1996-01-15 | Worcester Found Ex Biology | Hemmung von htlv-iii durch exogene oligonukleotide |
| US5866757A (en) * | 1992-06-02 | 1999-02-02 | Yeda Research And Development Co. Ltd. | Engraftment and development of xenogeneic cells in normal mammals having reconstituted hematopoetic deficient immune systems |
| WO1994007367A1 (en) * | 1992-09-29 | 1994-04-14 | Apollon, Inc. | Anti-viral oligomers that bind polypurine tracts of single-stranded rna or rna-dna hybrids |
| DK0664833T3 (da) | 1992-10-05 | 1997-04-14 | Hybridon Inc | Terapeutisk anti-HIV oligonukletid og lægemiddel |
| WO1994017086A1 (en) | 1993-01-25 | 1994-08-04 | Apollon, Inc. | Gene regulation by targeting putative intramolecular triple helix |
| US5550019A (en) * | 1993-05-26 | 1996-08-27 | La Jolla Cancer Research Foundation | Methods of identifying compounds which alter apoptosis |
| US5866755A (en) | 1993-06-14 | 1999-02-02 | Basf Aktiengellschaft | Animals transgenic for a tetracycline-regulated transcriptional inhibitor |
| WO1995006409A1 (en) | 1993-09-03 | 1995-03-09 | Systemix, Inc. | Genetically modified human hematopoietic stem cells and their progeny |
| US6265556B1 (en) * | 1994-12-02 | 2001-07-24 | The Burnham Institute | Nucleic acid encoding CD40 associated proteins |
| GB9425060D0 (en) * | 1994-12-13 | 1995-02-08 | Univ Birmingham | Carcinoma treatment |
| US5811524A (en) * | 1995-06-07 | 1998-09-22 | Idec Pharmaceuticals Corporation | Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof |
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| IL162111A0 (en) | 2001-12-22 | 2005-11-20 | 4Antibody Ag | Method for the generation of generically modified vertebrate precursor lymphocytes and use thereof for the production of heterologo |
| WO2003079757A2 (en) | 2002-03-20 | 2003-10-02 | Massachusetts Institute Of Technology | Hiv therapeutic |
| JP2004121237A (ja) * | 2002-09-05 | 2004-04-22 | Japan Science & Technology Agency | 体外免疫末梢血リンパ球を用いた抗原特異的抗体 |
| WO2004040969A1 (ja) * | 2002-11-07 | 2004-05-21 | Kumamoto Technology & Industry Foundation | Ganp導入トランスジェニック哺乳動物及びその利用 |
| GB2398783A (en) * | 2003-02-26 | 2004-09-01 | Antonio Lanzavecchia | A method for producing immortalised human B memory lymphocytes |
| BRPI0408315A (pt) * | 2003-03-14 | 2006-03-07 | Wyeth Corp | anticorpo isolado, composição farmacêutica, ácido nucleico isolado, vetor de expressão, célula hospedeira, métodos de produzir um anticorpo, de gerar um anticorpo ou fragmento de ligação de antìgeno, de regular uma resposta imune, de tratar ou prevenir um distúrbio associado com célula imune em um paciente, de tratar ou prevenir um distúrbio hiperproliferativo em um paciente, e, kit de diagnóstico |
| SI1694360T1 (sl) | 2003-11-04 | 2010-12-31 | Novartis Vaccines & Diagnostic | Uporaba antagonističnih anti-CD40 protiteles za zdravljenje avtoimunskih in vnetnih bolezni in zavrnitve transplantata organa |
| DK1692276T3 (da) * | 2003-11-19 | 2010-11-01 | Us Gov Health & Human Serv | Fremgangsmåde til induktion af udvikling og terminal differentiering af hukommelses-B-celler |
| GB0327384D0 (en) | 2003-11-25 | 2003-12-31 | Queen Mary & Westfield College | Gene therapy |
| US20050238626A1 (en) * | 2004-04-01 | 2005-10-27 | Lili Yang | Antigen specific T cell therapy |
| WO2005123923A2 (en) | 2004-06-17 | 2005-12-29 | Wolfgang Hillen | Inducer specific tetracycline repressor proteins and methods of use thereof |
| EP1627563A1 (en) | 2004-08-10 | 2006-02-22 | Academisch Medisch Centrum bij de Universiteit van Amsterdam | Means and methods for producing a stabilized cell of interest |
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| US7393923B2 (en) * | 2004-11-08 | 2008-07-01 | The Regents Of The University Of California | Red-shifted fluorescent proteins mPlum and mRaspberry and polynucleotides encoding the same |
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| WO2006132524A1 (en) | 2005-06-06 | 2006-12-14 | Academisch Medisch Centrum Bij De Universiteit Van Amsterdam | Means and methods for generating a t cell against an antigen of interest. |
| ES2366227T3 (es) | 2005-11-17 | 2011-10-18 | TET Systems GmbH & Co. KG | Sistemas de expresión inducibles. |
| WO2007067032A1 (en) | 2005-12-09 | 2007-06-14 | Academisch Medisch Cemtrum Bij De Universiteit Van Amsterdam | Means and methods for influencing the stability of cells |
| US9127251B2 (en) | 2005-12-09 | 2015-09-08 | Academisch Medisch Centrum Bij De Universiteit Van Amsterdam | Means and methods for influencing the stability of antibody producing cells |
| BRPI0807952A2 (pt) * | 2007-02-20 | 2014-06-10 | Anaptysbio Inc | Sistemas de hipermutação somática |
| EP1997830A1 (en) | 2007-06-01 | 2008-12-03 | AIMM Therapeutics B.V. | RSV specific binding molecules and means for producing them |
| US9683226B2 (en) * | 2009-04-03 | 2017-06-20 | Medical Research Council | Mutants of activation-induced cytidine deaminase (AID) and methods of use |
| KR101832201B1 (ko) | 2009-07-15 | 2018-02-28 | 에임 쎄라퓨틱스 비.브이. | 그람-양성 박테리아 특이적 결합 화합물 |
| EP2454283B1 (en) * | 2009-07-15 | 2018-03-14 | AIMM Therapeutics B.V. | Means and methods for producing high affinity antibodies |
| US8568726B2 (en) * | 2009-10-06 | 2013-10-29 | Medimmune Limited | RSV specific binding molecule |
| BR112012008173B1 (pt) | 2009-10-06 | 2021-12-07 | Medimmune Ltd | Anticorpo monoclonal humano recombinante, sintético ou isolado ou uma parte funcional do mesmo que se liga especificamente à proteína f do vírus sincicial respiratório, sequência de ácido nucleico isolada ou um equivalente funcional da mesma, vetor, combinação, composição farmacêutica, usos dos mesmos e método para produzir um anticorpo ou parte funcional do mesmo |
| ES2626671T3 (es) | 2010-12-02 | 2017-07-25 | Aimm Therapeutics B.V. | Medios y métodos para producir anticuerpos de alta afinidad |
| SG11201402780UA (en) | 2011-12-02 | 2014-10-30 | Aimm Therapeutics Bv | Influenza a virus specific antibodies |
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2006
- 2006-12-08 US US12/086,328 patent/US9127251B2/en active Active
- 2006-12-08 BR BR122021001906-1A patent/BR122021001906B1/pt active IP Right Grant
- 2006-12-08 HU HUE12175198A patent/HUE037580T2/hu unknown
- 2006-12-08 ES ES06824300T patent/ES2444465T5/es active Active
- 2006-12-08 EP EP06824300.5A patent/EP1974017B2/en active Active
- 2006-12-08 PT PT121751986T patent/PT2540820T/pt unknown
- 2006-12-08 DK DK12175198.6T patent/DK2540820T3/da active
- 2006-12-08 WO PCT/NL2006/000625 patent/WO2007067046A1/en not_active Ceased
- 2006-12-08 CA CA2633157A patent/CA2633157C/en active Active
- 2006-12-08 PT PT06824300T patent/PT1974017E/pt unknown
- 2006-12-08 PL PL12175198T patent/PL2540820T3/pl unknown
- 2006-12-08 NZ NZ60007506A patent/NZ600075A/en unknown
- 2006-12-08 EP EP12175198.6A patent/EP2540820B1/en active Active
- 2006-12-08 PL PL06824300.5T patent/PL1974017T5/pl unknown
- 2006-12-08 DK DK06824300.5T patent/DK1974017T4/da active
- 2006-12-08 NZ NZ59215906A patent/NZ592159A/xx unknown
- 2006-12-08 FI FIEP06824300.5T patent/FI1974017T4/fi active
- 2006-12-08 CA CA3015416A patent/CA3015416C/en active Active
- 2006-12-08 JP JP2008544276A patent/JP5753339B2/ja active Active
- 2006-12-08 ES ES12175198.6T patent/ES2660899T3/es active Active
- 2006-12-08 NZ NZ56954306A patent/NZ569543A/xx unknown
- 2006-12-08 BR BRPI0619579A patent/BRPI0619579B8/pt active IP Right Grant
- 2006-12-08 AU AU2006323315A patent/AU2006323315B2/en active Active
- 2006-12-08 EP EP18150705.4A patent/EP3327117A1/en active Pending
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2013
- 2013-02-05 JP JP2013020744A patent/JP5753547B2/ja active Active
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2014
- 2014-05-19 AU AU2014202709A patent/AU2014202709B2/en active Active
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2015
- 2015-08-26 US US14/836,335 patent/US9822339B2/en active Active
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2017
- 2017-06-02 US US15/612,096 patent/US10273454B2/en active Active
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