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DK1869032T3 - Pyrimidindervater til anvendelse som anticancermidler - Google Patents

Pyrimidindervater til anvendelse som anticancermidler

Info

Publication number
DK1869032T3
DK1869032T3 DK06726601T DK06726601T DK1869032T3 DK 1869032 T3 DK1869032 T3 DK 1869032T3 DK 06726601 T DK06726601 T DK 06726601T DK 06726601 T DK06726601 T DK 06726601T DK 1869032 T3 DK1869032 T3 DK 1869032T3
Authority
DK
Denmark
Prior art keywords
wounds
pyrimidine
anticancer agents
substituents
man
Prior art date
Application number
DK06726601T
Other languages
English (en)
Inventor
Andrew Peter Thomas
Thorsten Nowak
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0506883A external-priority patent/GB0506883D0/en
Priority claimed from GB0525953A external-priority patent/GB0525953D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK1869032T3 publication Critical patent/DK1869032T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK06726601T 2005-04-05 2006-03-31 Pyrimidindervater til anvendelse som anticancermidler DK1869032T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0506883A GB0506883D0 (en) 2005-04-05 2005-04-05 Chemical compounds
GB0525953A GB0525953D0 (en) 2005-12-21 2005-12-21 Chemical compounds
PCT/GB2006/001195 WO2006106307A1 (en) 2005-04-05 2006-03-31 Pyrimidine derivatives for use as anticancer agents

Publications (1)

Publication Number Publication Date
DK1869032T3 true DK1869032T3 (da) 2008-11-10

Family

ID=36641343

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06726601T DK1869032T3 (da) 2005-04-05 2006-03-31 Pyrimidindervater til anvendelse som anticancermidler

Country Status (18)

Country Link
US (1) US20080167297A1 (da)
EP (1) EP1869032B8 (da)
JP (1) JP2008534662A (da)
KR (1) KR20070116994A (da)
AT (1) ATE404554T1 (da)
AU (1) AU2006231116A1 (da)
BR (1) BRPI0609965A2 (da)
CA (1) CA2602372A1 (da)
DE (1) DE602006002271D1 (da)
DK (1) DK1869032T3 (da)
ES (1) ES2310406T3 (da)
HR (1) HRP20080505T3 (da)
IL (1) IL186034A0 (da)
MX (1) MX2007012345A (da)
NO (1) NO20074869L (da)
PT (1) PT1869032E (da)
SI (1) SI1869032T1 (da)
WO (1) WO2006106307A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010229134A1 (en) * 2009-03-23 2011-11-10 Msd K.K. Novel aminopyridine derivatives having Aurora A selective inhibitory action
US8367690B2 (en) * 2009-03-24 2013-02-05 Vertex Pharmaceuticals Inc. Aminopyridine derivatives having aurora a selective inhibitory action
US20110053916A1 (en) 2009-08-14 2011-03-03 Vertex Pharmaceuticals Incorporated Pyrimidine compounds as tuberculosis inhibitors
PL2748151T3 (pl) 2011-08-25 2016-09-30 Pirymidynowe inhibitory pde10
WO2023163712A1 (en) * 2022-02-25 2023-08-31 Nalo Therapeutics Modulators of myc family proto-oncogene protein
AR128608A1 (es) * 2022-02-25 2024-05-29 Nalo Therapeutics Moduladores de proteínas de protooncogenes de la familia myc

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2426180A1 (de) * 1974-05-29 1975-12-18 Bayer Ag Verfahren zum faerben von polyurethankunststoffen
ATE346064T1 (de) * 2000-09-15 2006-12-15 Vertex Pharma Pyrazolverbindungen als protein-kinasehemmer
WO2002068415A1 (en) * 2000-12-21 2002-09-06 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
US6939874B2 (en) * 2001-08-22 2005-09-06 Amgen Inc. Substituted pyrimidinyl derivatives and methods of use
MXPA05005477A (es) * 2002-11-21 2005-07-25 Chiron Corp Pirimidinas 2,4,6-trisustituidas como inhibidores de fosfotidilinositol (pi) 3-cinasa y su uso en el tratamiento del cancer.
KR20060123164A (ko) * 2003-10-17 2006-12-01 아스트라제네카 아베 암 치료에 사용하기 위한 4-(피라졸-3-일아미노)피리미딘유도체

Also Published As

Publication number Publication date
AU2006231116A1 (en) 2006-10-12
US20080167297A1 (en) 2008-07-10
BRPI0609965A2 (pt) 2011-10-11
CA2602372A1 (en) 2006-10-12
MX2007012345A (es) 2007-11-23
HRP20080505T3 (hr) 2008-11-30
ES2310406T3 (es) 2009-01-01
WO2006106307A1 (en) 2006-10-12
JP2008534662A (ja) 2008-08-28
IL186034A0 (en) 2008-02-09
NO20074869L (no) 2007-11-02
EP1869032B8 (en) 2009-03-25
ATE404554T1 (de) 2008-08-15
SI1869032T1 (sl) 2008-12-31
KR20070116994A (ko) 2007-12-11
EP1869032B1 (en) 2008-08-13
DE602006002271D1 (de) 2008-09-25
HK1114387A1 (en) 2008-10-31
PT1869032E (pt) 2008-10-21
EP1869032A1 (en) 2007-12-26

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