DK1732534T3 - Anvendelse af methylenamidderivater ved cardiovaskulære sygdomme - Google Patents
Anvendelse af methylenamidderivater ved cardiovaskulære sygdommeInfo
- Publication number
- DK1732534T3 DK1732534T3 DK05716814T DK05716814T DK1732534T3 DK 1732534 T3 DK1732534 T3 DK 1732534T3 DK 05716814 T DK05716814 T DK 05716814T DK 05716814 T DK05716814 T DK 05716814T DK 1732534 T3 DK1732534 T3 DK 1732534T3
- Authority
- DK
- Denmark
- Prior art keywords
- derivatives
- methylenamide
- cardiovascular diseases
- prevention
- formula
- Prior art date
Links
- WDWDWGRYHDPSDS-UHFFFAOYSA-N methanimine Chemical class N=C WDWDWGRYHDPSDS-UHFFFAOYSA-N 0.000 title abstract 3
- 208000024172 Cardiovascular disease Diseases 0.000 title abstract 2
- 206010019280 Heart failures Diseases 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 206010048554 Endothelial dysfunction Diseases 0.000 abstract 1
- 230000008694 endothelial dysfunction Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04100778 | 2004-02-27 | ||
| PCT/EP2005/050823 WO2005082347A1 (en) | 2004-02-27 | 2005-02-25 | Use of methylene amide derivatives in cardiovascular disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1732534T3 true DK1732534T3 (da) | 2008-11-17 |
Family
ID=34896106
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05716814T DK1732534T3 (da) | 2004-02-27 | 2005-02-25 | Anvendelse af methylenamidderivater ved cardiovaskulære sygdomme |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20070185118A1 (da) |
| EP (1) | EP1732534B1 (da) |
| JP (1) | JP5001138B2 (da) |
| KR (1) | KR101188940B1 (da) |
| CN (1) | CN1933827B (da) |
| AT (1) | ATE401877T1 (da) |
| AU (1) | AU2005216649B2 (da) |
| BR (1) | BRPI0508080A (da) |
| CA (1) | CA2554919C (da) |
| CY (1) | CY1108252T1 (da) |
| DE (1) | DE602005008412D1 (da) |
| DK (1) | DK1732534T3 (da) |
| EA (1) | EA011811B1 (da) |
| ES (1) | ES2308458T3 (da) |
| HR (1) | HRP20080367T3 (da) |
| IL (1) | IL177494A (da) |
| NO (1) | NO20064295L (da) |
| PL (1) | PL1732534T3 (da) |
| PT (1) | PT1732534E (da) |
| RS (1) | RS50596B (da) |
| SI (1) | SI1732534T1 (da) |
| UA (1) | UA84453C2 (da) |
| WO (1) | WO2005082347A1 (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA012260B1 (ru) * | 2002-01-29 | 2009-08-28 | Лаборатуар Сероно Са | ЗАМЕЩЁННЫЕ ПРОИЗВОДНЫЕ МЕТИЛЕНАМИДА В КАЧЕСТВЕ МОДУЛЯТОРОВ ПРОТЕИНТИРОЗИНФОСФАТАЗ (PTPs) |
| EP1654247B1 (en) | 2003-07-21 | 2010-01-20 | Merck Serono SA | Alkynyl aryl carboxamides |
| US7884234B2 (en) * | 2006-10-12 | 2011-02-08 | Institute Of Medicinal Molecular Design, Inc. | N-phenyloxamide derivatives |
| US8633245B2 (en) * | 2008-04-11 | 2014-01-21 | Institute Of Medicinal Molecular Design, Inc. | PAI-1 inhibitor |
| TW201319023A (zh) | 2011-08-29 | 2013-05-16 | Ticona Llc | 具改良低剪切黏度之熱向性液晶聚合物 |
| TW201319223A (zh) | 2011-08-29 | 2013-05-16 | Ticona Llc | 高流量液晶聚合物組合物 |
| US9045685B2 (en) | 2011-08-29 | 2015-06-02 | Ticona Llc | Cast molded parts formed from a liquid crystalline polymer |
| TW201313884A (zh) | 2011-08-29 | 2013-04-01 | Ticona Llc | 液晶聚合物之固態聚合 |
| CN103764793B (zh) | 2011-08-29 | 2016-09-14 | 提克纳有限责任公司 | 高流动液晶聚合物组合物 |
| JP2014529627A (ja) | 2011-08-29 | 2014-11-13 | ティコナ・エルエルシー | 芳香族アミド化合物 |
| US9057016B2 (en) | 2011-08-29 | 2015-06-16 | Ticona Llc | Melt polymerization of low melt viscosity liquid crystalline polymers |
| WO2013032971A1 (en) | 2011-08-29 | 2013-03-07 | Ticona Llc | Melt-extruded substrate for use in thermoformed articles |
| JP2014525499A (ja) | 2011-08-29 | 2014-09-29 | ティコナ・エルエルシー | 低い融解温度をもつ耐熱性液晶ポリマー組成物 |
| WO2014095815A1 (en) | 2012-12-17 | 2014-06-26 | Shell Internationale Research Maatschappij B.V. | Integrated gas-to-liquid condensate process |
| WO2014130275A2 (en) | 2013-02-22 | 2014-08-28 | Ticona Llc | High performance polymer composition with improved flow properties |
| CN113912988A (zh) | 2013-06-07 | 2022-01-11 | 提克纳有限责任公司 | 高强度热致液晶聚合物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6985200A (en) * | 1999-09-10 | 2001-04-17 | Novo Nordisk A/S | Modulators of protein tyrosine phosphatases (ptpases) |
| US6627767B2 (en) * | 2000-08-29 | 2003-09-30 | Abbott Laboratories | Amino(oxo) acetic acid protein tyrosine phosphatase inhibitors |
| DE10117823A1 (de) * | 2001-04-10 | 2002-10-17 | Merck Patent Gmbh | Oxalsäurederivate |
| AR034374A1 (es) * | 2001-06-07 | 2004-02-18 | Wyeth Corp | Combinacion de un inhibidor de ptpasa y un inhibidor de ace |
| WO2002098408A1 (en) * | 2001-06-07 | 2002-12-12 | Wyeth | Ptpase inhibitors for improving cardiovascular risk profile |
| EA012260B1 (ru) * | 2002-01-29 | 2009-08-28 | Лаборатуар Сероно Са | ЗАМЕЩЁННЫЕ ПРОИЗВОДНЫЕ МЕТИЛЕНАМИДА В КАЧЕСТВЕ МОДУЛЯТОРОВ ПРОТЕИНТИРОЗИНФОСФАТАЗ (PTPs) |
-
2005
- 2005-02-25 CN CN2005800087220A patent/CN1933827B/zh not_active Expired - Fee Related
- 2005-02-25 CA CA2554919A patent/CA2554919C/en not_active Expired - Fee Related
- 2005-02-25 JP JP2007500226A patent/JP5001138B2/ja not_active Expired - Fee Related
- 2005-02-25 RS RSP-2008/0353A patent/RS50596B/sr unknown
- 2005-02-25 DK DK05716814T patent/DK1732534T3/da active
- 2005-02-25 BR BRPI0508080-0A patent/BRPI0508080A/pt not_active IP Right Cessation
- 2005-02-25 EP EP05716814A patent/EP1732534B1/en not_active Expired - Lifetime
- 2005-02-25 PT PT05716814T patent/PT1732534E/pt unknown
- 2005-02-25 US US10/590,808 patent/US20070185118A1/en not_active Abandoned
- 2005-02-25 ES ES05716814T patent/ES2308458T3/es not_active Expired - Lifetime
- 2005-02-25 DE DE602005008412T patent/DE602005008412D1/de not_active Expired - Lifetime
- 2005-02-25 HR HR20080367T patent/HRP20080367T3/xx unknown
- 2005-02-25 PL PL05716814T patent/PL1732534T3/pl unknown
- 2005-02-25 EA EA200601511A patent/EA011811B1/ru not_active IP Right Cessation
- 2005-02-25 UA UAA200609879A patent/UA84453C2/ru unknown
- 2005-02-25 KR KR1020067019715A patent/KR101188940B1/ko not_active Expired - Fee Related
- 2005-02-25 AT AT05716814T patent/ATE401877T1/de active
- 2005-02-25 SI SI200530349T patent/SI1732534T1/sl unknown
- 2005-02-25 AU AU2005216649A patent/AU2005216649B2/en not_active Ceased
- 2005-02-25 WO PCT/EP2005/050823 patent/WO2005082347A1/en not_active Ceased
-
2006
- 2006-08-15 IL IL177494A patent/IL177494A/en not_active IP Right Cessation
- 2006-09-22 NO NO20064295A patent/NO20064295L/no not_active Application Discontinuation
-
2008
- 2008-08-11 CY CY20081100844T patent/CY1108252T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20070185118A1 (en) | 2007-08-09 |
| UA84453C2 (ru) | 2008-10-27 |
| JP2007524701A (ja) | 2007-08-30 |
| IL177494A (en) | 2011-06-30 |
| KR101188940B1 (ko) | 2012-10-08 |
| HRP20080367T3 (en) | 2008-09-30 |
| ATE401877T1 (de) | 2008-08-15 |
| JP5001138B2 (ja) | 2012-08-15 |
| ES2308458T3 (es) | 2008-12-01 |
| CA2554919A1 (en) | 2005-09-09 |
| CN1933827B (zh) | 2011-07-27 |
| AU2005216649B2 (en) | 2010-09-09 |
| IL177494A0 (en) | 2006-12-31 |
| CA2554919C (en) | 2013-04-16 |
| PL1732534T3 (pl) | 2008-12-31 |
| RS50596B (sr) | 2010-05-07 |
| EA011811B1 (ru) | 2009-06-30 |
| EP1732534B1 (en) | 2008-07-23 |
| BRPI0508080A (pt) | 2007-07-17 |
| PT1732534E (pt) | 2008-08-08 |
| AU2005216649A1 (en) | 2005-09-09 |
| HK1098073A1 (en) | 2007-07-13 |
| WO2005082347A1 (en) | 2005-09-09 |
| CY1108252T1 (el) | 2014-02-12 |
| KR20060129066A (ko) | 2006-12-14 |
| CN1933827A (zh) | 2007-03-21 |
| EP1732534A1 (en) | 2006-12-20 |
| EA200601511A1 (ru) | 2007-02-27 |
| SI1732534T1 (sl) | 2008-10-31 |
| NO20064295L (no) | 2006-09-22 |
| DE602005008412D1 (de) | 2008-09-04 |
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