DK1707568T3 - Farmaceutisk sammensætning til anvendelse i behandlingen af ovariecancer hos et menneske, der har sygdommen - Google Patents
Farmaceutisk sammensætning til anvendelse i behandlingen af ovariecancer hos et menneske, der har sygdommenInfo
- Publication number
- DK1707568T3 DK1707568T3 DK05076845.6T DK05076845T DK1707568T3 DK 1707568 T3 DK1707568 T3 DK 1707568T3 DK 05076845 T DK05076845 T DK 05076845T DK 1707568 T3 DK1707568 T3 DK 1707568T3
- Authority
- DK
- Denmark
- Prior art keywords
- pharmaceutical composition
- human
- topotecan
- treatment
- ovarian cancer
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 5
- 206010033128 Ovarian cancer Diseases 0.000 title abstract 3
- 206010061535 Ovarian neoplasm Diseases 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- UCFGDBYHRUNTLO-QHCPKHFHSA-N topotecan Chemical compound C1=C(O)C(CN(C)C)=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)[C@]5(O)CC)C4=NC2=C1 UCFGDBYHRUNTLO-QHCPKHFHSA-N 0.000 abstract 5
- 229960000303 topotecan Drugs 0.000 abstract 5
- 239000000203 mixture Substances 0.000 abstract 2
- 238000002560 therapeutic procedure Methods 0.000 abstract 2
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/16—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4741—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having oxygen as a ring hetero atom, e.g. tubocuraran derivatives, noscapine, bicuculline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65894891A | 1991-02-21 | 1991-02-21 | |
| EP92907833A EP0572557B1 (en) | 1991-02-21 | 1992-02-07 | Use of topotecan in the manufacture of a medicament for use in the treatment of ovarian cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1707568T3 true DK1707568T3 (da) | 2010-11-08 |
Family
ID=24643386
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92907833.5T DK0572557T3 (da) | 1991-02-21 | 1992-02-07 | Anvendelse af topotecan til fremstilling af et lægemiddel til anvendelse ved behandling af kræft i æggestokkene |
| DK05076845.6T DK1707568T3 (da) | 1991-02-21 | 1992-02-07 | Farmaceutisk sammensætning til anvendelse i behandlingen af ovariecancer hos et menneske, der har sygdommen |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92907833.5T DK0572557T3 (da) | 1991-02-21 | 1992-02-07 | Anvendelse af topotecan til fremstilling af et lægemiddel til anvendelse ved behandling af kræft i æggestokkene |
Country Status (12)
| Country | Link |
|---|---|
| EP (3) | EP1707568B1 (da) |
| JP (1) | JP2778632B2 (da) |
| KR (1) | KR930702983A (da) |
| AT (2) | ATE476182T1 (da) |
| AU (1) | AU663312B2 (da) |
| CA (1) | CA2103708C (da) |
| DE (2) | DE69233793D1 (da) |
| DK (2) | DK0572557T3 (da) |
| ES (2) | ES2349037T3 (da) |
| MX (1) | MX9200754A (da) |
| PT (1) | PT100156B (da) |
| WO (1) | WO1992014469A1 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101255406B (zh) * | 2005-04-22 | 2010-05-26 | 李红霞 | 人卵巢癌耐药细胞株 |
| ES2371171B1 (es) * | 2010-06-08 | 2012-11-16 | Consejo Superior De Investigaciones Científicas (Csic) | Derivados de camptotecina como agentes antitumorales. |
| CN102477042A (zh) * | 2010-11-26 | 2012-05-30 | 复旦大学 | 10-羟基喜树碱衍生物及其制备方法和用途 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5004758A (en) | 1987-12-01 | 1991-04-02 | Smithkline Beecham Corporation | Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells |
-
1992
- 1992-02-07 DK DK92907833.5T patent/DK0572557T3/da active
- 1992-02-07 CA CA002103708A patent/CA2103708C/en not_active Expired - Lifetime
- 1992-02-07 ES ES05076845T patent/ES2349037T3/es not_active Expired - Lifetime
- 1992-02-07 JP JP4507268A patent/JP2778632B2/ja not_active Expired - Lifetime
- 1992-02-07 DE DE69233793T patent/DE69233793D1/de not_active Expired - Lifetime
- 1992-02-07 ES ES92907833T patent/ES2334178T3/es not_active Expired - Lifetime
- 1992-02-07 KR KR1019930702490A patent/KR930702983A/ko not_active Ceased
- 1992-02-07 WO PCT/US1992/001028 patent/WO1992014469A1/en not_active Ceased
- 1992-02-07 AT AT05076845T patent/ATE476182T1/de active
- 1992-02-07 DK DK05076845.6T patent/DK1707568T3/da active
- 1992-02-07 EP EP05076845A patent/EP1707568B1/en not_active Expired - Lifetime
- 1992-02-07 AU AU14616/92A patent/AU663312B2/en not_active Expired
- 1992-02-07 EP EP05076846A patent/EP1690542A3/en not_active Withdrawn
- 1992-02-07 DE DE69233773T patent/DE69233773D1/de not_active Expired - Lifetime
- 1992-02-07 EP EP92907833A patent/EP0572557B1/en not_active Expired - Lifetime
- 1992-02-07 AT AT92907833T patent/ATE444755T1/de active
- 1992-02-21 PT PT100156A patent/PT100156B/pt not_active IP Right Cessation
- 1992-02-21 MX MX9200754A patent/MX9200754A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1707568A2 (en) | 2006-10-04 |
| DE69233793D1 (de) | 2010-09-16 |
| EP1690542A2 (en) | 2006-08-16 |
| AU663312B2 (en) | 1995-10-05 |
| KR930702983A (ko) | 1993-11-29 |
| EP1707568B1 (en) | 2010-08-04 |
| ES2349037T3 (es) | 2010-12-22 |
| ATE476182T1 (de) | 2010-08-15 |
| ATE444755T1 (de) | 2009-10-15 |
| PT100156A (pt) | 1993-05-31 |
| EP0572557B1 (en) | 2009-10-07 |
| ES2334178T3 (es) | 2010-03-05 |
| AU1461692A (en) | 1992-09-15 |
| CA2103708C (en) | 2004-04-27 |
| EP1690542A3 (en) | 2008-03-26 |
| DE69233773D1 (de) | 2009-11-19 |
| EP0572557A4 (en) | 1993-12-29 |
| EP1707568A3 (en) | 2008-03-26 |
| EP0572557A1 (en) | 1993-12-08 |
| HK1012265A1 (en) | 1999-07-30 |
| JP2778632B2 (ja) | 1998-07-23 |
| MX9200754A (es) | 1992-08-01 |
| DK0572557T3 (da) | 2010-02-01 |
| WO1992014469A1 (en) | 1992-09-03 |
| PT100156B (pt) | 1999-09-30 |
| JPH06505740A (ja) | 1994-06-30 |
| CA2103708A1 (en) | 1992-08-22 |
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