DK1706457T3 - Fremstilling af 3-hydroxypropionsyre ved anvendelse af beta-alanin/pyruvataminotransferase - Google Patents
Fremstilling af 3-hydroxypropionsyre ved anvendelse af beta-alanin/pyruvataminotransferaseInfo
- Publication number
- DK1706457T3 DK1706457T3 DK04821820.0T DK04821820T DK1706457T3 DK 1706457 T3 DK1706457 T3 DK 1706457T3 DK 04821820 T DK04821820 T DK 04821820T DK 1706457 T3 DK1706457 T3 DK 1706457T3
- Authority
- DK
- Denmark
- Prior art keywords
- alanine
- beta
- hydroxypropionic acid
- pyruvataminotranspherase
- preparation
- Prior art date
Links
- UCMIRNVEIXFBKS-UHFFFAOYSA-N beta-alanine Chemical compound NCCC(O)=O UCMIRNVEIXFBKS-UHFFFAOYSA-N 0.000 title abstract 6
- ALRHLSYJTWAHJZ-UHFFFAOYSA-N 3-hydroxypropionic acid Chemical compound OCCC(O)=O ALRHLSYJTWAHJZ-UHFFFAOYSA-N 0.000 title abstract 4
- 229940000635 beta-alanine Drugs 0.000 title abstract 3
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 108010025593 phenylalanine (histidine) aminotransferase Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
- C12P7/625—Polyesters of hydroxy carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y206/00—Transferases transferring nitrogenous groups (2.6)
- C12Y206/01—Transaminases (2.6.1)
- C12Y206/01018—Beta-alanine-pyruvate transaminase (2.6.1.18)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52735703P | 2003-12-04 | 2003-12-04 | |
| PCT/US2004/040827 WO2005118719A2 (en) | 2003-12-04 | 2004-12-06 | Production of 3-hydroxypropionic acid using beta-alanine/pyruvate aminotransferase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1706457T3 true DK1706457T3 (da) | 2012-05-21 |
Family
ID=35463438
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04821820.0T DK1706457T3 (da) | 2003-12-04 | 2004-12-06 | Fremstilling af 3-hydroxypropionsyre ved anvendelse af beta-alanin/pyruvataminotransferase |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US7700319B2 (da) |
| EP (1) | EP1706457B1 (da) |
| AT (1) | ATE543873T1 (da) |
| BR (1) | BRPI0416546A (da) |
| DK (1) | DK1706457T3 (da) |
| WO (1) | WO2005118719A2 (da) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR031480A1 (es) | 2000-11-20 | 2003-09-24 | Cargill Inc | Acido 3-hidroxipropionico y otros compuestos organicos |
| EP1575881B1 (en) * | 2002-01-18 | 2009-05-27 | Novozymes A/S | Alanine 2,3- aminomutase |
| EP2292750A3 (en) * | 2004-07-30 | 2011-12-21 | Novozymes A/S | Alanine 2, 3 aminomutases |
| EP1805304A2 (en) | 2004-10-25 | 2007-07-11 | Codexis, Inc. | Improved alanine 2,3-aminomutases and related polynucleotides |
| US8030051B2 (en) | 2005-10-14 | 2011-10-04 | Codexis, Inc. | Alanine 2,3-aminomutases and related polynucleotides |
| CN105078773A (zh) | 2006-02-10 | 2015-11-25 | 杜邦塔特和莱尔生物产品有限责任公司 | 包括可再生基生物降解型1,3-丙二醇的生物降解型组合物 |
| CN101442910A (zh) | 2006-03-13 | 2009-05-27 | 卡吉尔公司 | 具有从磷酸二羟丙酮到甘油的途径被破坏的酵母细胞 |
| US8030045B2 (en) | 2006-08-30 | 2011-10-04 | Cargill, Incorporated | Beta-alanine/alpha-ketoglutarate aminotransferase for 3-hydroxypropionic acid production |
| WO2008089102A2 (en) * | 2007-01-12 | 2008-07-24 | Regents Of The University Of Colorado | Compositions and methods for enhancing tolerance for the production of organic chemicals produced by microorganisms |
| US8048624B1 (en) | 2007-12-04 | 2011-11-01 | Opx Biotechnologies, Inc. | Compositions and methods for 3-hydroxypropionate bio-production from biomass |
| DE102008020688B3 (de) | 2008-04-24 | 2009-11-05 | Evonik Stockhausen Gmbh | Verfahren zur Herstellung und Aufreinigung wässriger Phasen |
| CA2731509A1 (en) * | 2008-07-23 | 2010-01-28 | Opx Biotechnologies, Inc. | Methods, systems and compositions for increased microorganism tolerance to and production of 3-hydroxypropionic acid (3-hp) |
| WO2010031083A2 (en) * | 2008-09-15 | 2010-03-18 | Opx Biotechnologies, Inc. | Methods, systems and compositions related to reduction of conversions of microbially produced 3-hydroxypropionic acid (3-hp) to aldehyde metabolites |
| MX2012003604A (es) | 2009-09-27 | 2012-09-12 | Opx Biotechnologies Inc | Metodo para producir acido 3-hidroxipropionico y otros productos. |
| US8809027B1 (en) | 2009-09-27 | 2014-08-19 | Opx Biotechnologies, Inc. | Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase |
| US20110125118A1 (en) * | 2009-11-20 | 2011-05-26 | Opx Biotechnologies, Inc. | Production of an Organic Acid and/or Related Chemicals |
| WO2011094457A1 (en) * | 2010-01-27 | 2011-08-04 | Opx Biotechnologies, Inc. | Microorganism production of high-valve chemical products, and related compositions, methods and systems |
| CN102781901B (zh) | 2010-02-11 | 2016-08-03 | 梅塔玻利克斯公司 | 用于从经遗传修饰的聚羟基链烷酸酯生物质制备单体组分的方法 |
| US8911978B2 (en) | 2010-07-02 | 2014-12-16 | Metabolic Explorer | Method for the preparation of hydroxy acids |
| JP6061862B2 (ja) | 2010-11-22 | 2017-01-18 | カーギル，インコーポレイティド | ３‐ヒドロキシプロピオン酸生産用の組成物及び方法 |
| IN2014CN03187A (da) | 2011-09-30 | 2015-07-03 | Novozymes Inc | |
| EP2828383A1 (en) * | 2012-03-20 | 2015-01-28 | Metabolix, Inc. | Genetically engineered microorganisms for the production of poly-4-hydroxybutyrate |
| WO2013173711A1 (en) | 2012-05-18 | 2013-11-21 | Novozymes A/S | Bacterial mutants with improved transformation efficiency |
| CN104350034B (zh) | 2012-06-08 | 2018-07-31 | Cj 第一制糖株式会社 | 可再生丙烯酸生产和自其制备的产物 |
| CA2881666A1 (en) | 2012-08-10 | 2014-02-13 | Opx Biotechnologies, Inc. | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
| EP2900689B1 (en) | 2012-09-27 | 2017-08-02 | Novozymes, Inc. | Bacterial mutants with improved transformation efficiency |
| WO2014057036A1 (en) | 2012-10-11 | 2014-04-17 | Technical University Of Denmark | Genetically engineered yeast |
| AU2013352418B2 (en) | 2012-11-30 | 2016-12-08 | Novozymes, Inc. | 3-Hydroxypropionic Acid production by recombinant yeasts |
| JP2016518821A (ja) | 2013-03-15 | 2016-06-30 | カーギル・インコーポレイテッド | ３−ヒドロキシプロピオン酸の回収 |
| CA2905602A1 (en) | 2013-03-15 | 2014-09-18 | Sarah M. Hoyt | Flash evaporation for product purification and recovery |
| US9447438B2 (en) | 2013-03-15 | 2016-09-20 | Cargill, Incorporated | Acetyl-coA carboxylases |
| KR20160018568A (ko) * | 2013-06-05 | 2016-02-17 | 란자테크 뉴질랜드 리미티드 | 발효 경로를 통한 플럭스의 증가를 나타내는 재조합 미생물 |
| US10077455B2 (en) | 2013-06-14 | 2018-09-18 | Technical University Of Denmark | 3HP tolerance |
| BR112016001026A2 (pt) | 2013-07-19 | 2017-10-24 | Cargill Inc | organismo geneticamente modificado |
| US11408013B2 (en) | 2013-07-19 | 2022-08-09 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
| EP2993228B1 (en) | 2014-09-02 | 2019-10-09 | Cargill, Incorporated | Production of fatty acid esters |
| KR101730035B1 (ko) * | 2015-03-20 | 2017-04-26 | 한국과학기술원 | L-아스파르트산 유도체를 생산하는 변이미생물 및 이를 이용한 l-아스파르트산 유도체의 제조방법 |
| US11345938B2 (en) | 2017-02-02 | 2022-05-31 | Cargill, Incorporated | Genetically modified cells that produce C6-C10 fatty acid derivatives |
| CN110494553B (zh) * | 2017-04-13 | 2023-07-04 | 协和发酵生化株式会社 | 茶氨酸的制造方法 |
| KR102725416B1 (ko) * | 2021-02-08 | 2024-11-04 | 란자테크, 인크. | 재조합 미생물 및 이의 용도 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60030403D1 (de) | 1999-08-30 | 2006-10-12 | Wisconsin Alumni Res Found | Herstellung von 3-hydroxypropionsäure in rekombinanten organismen |
| AR031480A1 (es) | 2000-11-20 | 2003-09-24 | Cargill Inc | Acido 3-hidroxipropionico y otros compuestos organicos |
| EP1575881B1 (en) | 2002-01-18 | 2009-05-27 | Novozymes A/S | Alanine 2,3- aminomutase |
| EP2292750A3 (en) | 2004-07-30 | 2011-12-21 | Novozymes A/S | Alanine 2, 3 aminomutases |
-
2004
- 2004-12-06 AT AT04821820T patent/ATE543873T1/de active
- 2004-12-06 EP EP04821820A patent/EP1706457B1/en not_active Expired - Lifetime
- 2004-12-06 BR BRPI0416546-2A patent/BRPI0416546A/pt not_active Application Discontinuation
- 2004-12-06 US US10/581,570 patent/US7700319B2/en not_active Expired - Fee Related
- 2004-12-06 DK DK04821820.0T patent/DK1706457T3/da active
- 2004-12-06 WO PCT/US2004/040827 patent/WO2005118719A2/en not_active Ceased
-
2010
- 2010-02-03 US US12/699,715 patent/US7785837B2/en not_active Expired - Fee Related
- 2010-06-29 US US12/826,401 patent/US8124388B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20100267115A1 (en) | 2010-10-21 |
| US7785837B2 (en) | 2010-08-31 |
| EP1706457A2 (en) | 2006-10-04 |
| EP1706457B1 (en) | 2012-02-01 |
| ATE543873T1 (de) | 2012-02-15 |
| US7700319B2 (en) | 2010-04-20 |
| BRPI0416546A (pt) | 2007-01-09 |
| US8124388B2 (en) | 2012-02-28 |
| US20070107080A1 (en) | 2007-05-10 |
| US20100136638A1 (en) | 2010-06-03 |
| WO2005118719A3 (en) | 2006-09-21 |
| WO2005118719A2 (en) | 2005-12-15 |
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