DK1753760T3 - 4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl) -amide - Google Patents

4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl) -amide

Info

Publication number: DK1753760T3
Authority: DK; Denmark
Prior art keywords: benzothiazol; morpholin; piperidine; methoxy; amide
Prior art date: 2004-05-24

Application number

DK05741185T

Other languages

Danish (da)

Inventor

Alexander Flohr

Sonia Maria Poli

Lucinda Steward

Jean-Luc Moreau

Claus Riemer

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-05-24

Filing date

2005-05-17

Publication date

2008-04-14

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34967309&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1753760(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2005-05-17 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2008-04-14 Application granted granted Critical

2008-04-14 Publication of DK1753760T3 publication Critical patent/DK1753760T3/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Addiction (AREA)
Psychiatry (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Psychology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Immunology (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Vascular Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK05741185T 2004-05-24 2005-05-17 4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl) -amide DK1753760T3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP04102262		2004-05-24
PCT/EP2005/005329 WO2005116026A1 (en)	2004-05-24	2005-05-17	4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide

Publications (1)

Publication Number	Publication Date
DK1753760T3 true DK1753760T3 (en)	2008-04-14

Family

ID=34967309

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK05741185T DK1753760T3 (en)	2004-05-24	2005-05-17	4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl) -amide

Country Status (38)

Country	Link
US (1)	US7368446B2 (en)
EP (1)	EP1753760B1 (en)
JP (1)	JP4668265B2 (en)
CN (1)	CN1956983B (en)
AR (1)	AR048973A1 (en)
AT (1)	ATE382619T1 (en)
AU (1)	AU2005247567B2 (en)
BR (1)	BRPI0511543B1 (en)
CA (1)	CA2567703C (en)
CR (1)	CR8703A (en)
CY (1)	CY1108104T1 (en)
DE (1)	DE602005004142T2 (en)
DK (1)	DK1753760T3 (en)
DO (1)	DOP2005000091A (en)
EA (1)	EA011279B1 (en)
EC (1)	ECSP067018A (en)
ES (1)	ES2297710T3 (en)
GT (1)	GT200500124A (en)
HN (1)	HN2005000238A (en)
HR (1)	HRP20080027T3 (en)
IL (1)	IL179364A (en)
MA (1)	MA28601B1 (en)
MX (1)	MXPA06013417A (en)
MY (1)	MY140011A (en)
NO (1)	NO336939B1 (en)
NZ (1)	NZ550763A (en)
PA (1)	PA8633901A1 (en)
PE (1)	PE20060274A1 (en)
PL (1)	PL1753760T3 (en)
PT (1)	PT1753760E (en)
RS (1)	RS50574B (en)
SI (1)	SI1753760T1 (en)
SV (1)	SV2006002125A (en)
TN (1)	TNSN06371A1 (en)
TW (1)	TWI358297B (en)
UA (1)	UA87142C2 (en)
WO (1)	WO2005116026A1 (en)
ZA (1)	ZA200609136B (en)

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ATE359075T1 (en) *	2002-12-20	2007-05-15	Niconovum Ab	CHEMICALLY AND PHYSICALLY STABLE PARTICLE MATERIAL CONTAINING NICOTINE AND MICROCRYSTALLINE CELLULOSE
AU2007224584A1 (en)	2006-03-16	2007-09-20	Niconovum Ab	Improved snuff composition
WO2009015236A1 (en) *	2007-07-23	2009-01-29	Synosia Therapeutics	4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide for the treatment of post-traumatic stress disorder
HRP20150355T1 (en)	2009-01-12	2015-06-19	Pfizer Limited	SULFONAMIDNI DERIVATI
US8168785B2 (en)	2009-06-17	2012-05-01	Biotie Therapies, Inc.	Benzothiazole derivatives
WO2011101861A1 (en)	2010-01-29	2011-08-25	Msn Laboratories Limited	Process for preparation of dpp-iv inhibitors
US9145407B2 (en)	2010-07-09	2015-09-29	Pfizer Limited	Sulfonamide compounds
WO2012060844A1 (en) *	2010-11-05	2012-05-10	Biotie Therapies, Inc	A2a antagonists as cognition and motor function enhancers
EP2838530B1 (en) *	2012-04-20	2017-04-05	UCB Biopharma SPRL	Methods for treating parkinson's disease
AU2016278846B2 (en) *	2015-06-19	2021-08-05	Biotie Therapies, Inc.	Controlled-release tozadenant formulations
WO2018059531A1 (en) *	2016-09-30	2018-04-05	苏州晶云药物科技有限公司	Crystal form of adenosine a2a receptor antagonist drug and preparation method and use thereof
US11192899B2 (en)	2017-08-21	2021-12-07	Merck Patent Gmbh	Quinoxaline derivatives as adenosine receptor antagonists
CN110997662B (en)	2017-08-21	2023-10-31	默克专利股份公司	Benzimidazole derivatives as adenosine receptor antagonists
WO2019141096A1 (en) *	2018-01-19	2019-07-25	四川科伦博泰生物医药股份有限公司	Substituted urea compound and preparation method and use thereof
CA3123856A1 (en)	2018-12-20	2020-06-25	Biotie Therapies, Inc.	Methods for treating cancer using tozadenant
DE102019110904B4 (en)	2019-04-26	2022-01-20	Helmholtz-Zentrum Dresden - Rossendorf E. V.	N-(4-methoxy-7-morpholinobenzo[d]thiazol-2-yl)acetamide derivatives and their use
CN116407539B (en) *	2021-12-30	2025-01-10	上海现代药物制剂工程研究中心有限公司	Use of epiprazole methyl fatty acid ester

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US6713499B2 (en) *	2001-12-12	2004-03-30	Hoffman-La Roche Inc.	7-Amino-benzothiazole derivatives

2005
- 2005-05-17 EP EP05741185A patent/EP1753760B1/en not_active Expired - Lifetime
- 2005-05-17 RS RSP-2008/0125A patent/RS50574B/en unknown
- 2005-05-17 MX MXPA06013417A patent/MXPA06013417A/en active IP Right Grant
- 2005-05-17 CA CA2567703A patent/CA2567703C/en not_active Expired - Lifetime
- 2005-05-17 NZ NZ550763A patent/NZ550763A/en not_active IP Right Cessation
- 2005-05-17 SI SI200530160T patent/SI1753760T1/en unknown
- 2005-05-17 JP JP2007513750A patent/JP4668265B2/en not_active Expired - Fee Related
- 2005-05-17 DK DK05741185T patent/DK1753760T3/en active
- 2005-05-17 HR HR20080027T patent/HRP20080027T3/en unknown
- 2005-05-17 PT PT05741185T patent/PT1753760E/en unknown
- 2005-05-17 AT AT05741185T patent/ATE382619T1/en active
- 2005-05-17 EA EA200602048A patent/EA011279B1/en not_active IP Right Cessation
- 2005-05-17 AU AU2005247567A patent/AU2005247567B2/en not_active Expired
- 2005-05-17 CN CN200580016875XA patent/CN1956983B/en not_active Expired - Fee Related
- 2005-05-17 UA UAA200613530A patent/UA87142C2/en unknown
- 2005-05-17 BR BRPI0511543-4A patent/BRPI0511543B1/en not_active IP Right Cessation
- 2005-05-17 ES ES05741185T patent/ES2297710T3/en not_active Expired - Lifetime
- 2005-05-17 PL PL05741185T patent/PL1753760T3/en unknown
- 2005-05-17 WO PCT/EP2005/005329 patent/WO2005116026A1/en not_active Ceased
- 2005-05-17 DE DE602005004142T patent/DE602005004142T2/en not_active Expired - Lifetime
- 2005-05-18 US US11/132,019 patent/US7368446B2/en not_active Expired - Lifetime
- 2005-05-20 TW TW094116495A patent/TWI358297B/en not_active IP Right Cessation
- 2005-05-20 DO DO2005000091A patent/DOP2005000091A/en unknown
- 2005-05-20 MY MYPI20052309A patent/MY140011A/en unknown
- 2005-05-23 AR ARP050102104A patent/AR048973A1/en not_active Application Discontinuation
- 2005-05-23 GT GT200500124A patent/GT200500124A/en unknown
- 2005-05-23 PE PE2005000569A patent/PE20060274A1/en active IP Right Grant
- 2005-05-23 PA PA20058633901A patent/PA8633901A1/en unknown
- 2005-05-23 HN HN2005000238A patent/HN2005000238A/en unknown
- 2005-05-24 SV SV2005002125A patent/SV2006002125A/en unknown
2006
- 2006-10-24 CR CR8703A patent/CR8703A/en unknown
- 2006-11-02 ZA ZA200609136A patent/ZA200609136B/en unknown
- 2006-11-14 TN TNP2006000371A patent/TNSN06371A1/en unknown
- 2006-11-16 IL IL179364A patent/IL179364A/en active IP Right Grant
- 2006-11-21 EC EC2006007018A patent/ECSP067018A/en unknown
- 2006-11-22 MA MA29481A patent/MA28601B1/en unknown
- 2006-12-12 NO NO20065732A patent/NO336939B1/en not_active IP Right Cessation
2008
- 2008-02-28 CY CY20081100232T patent/CY1108104T1/en unknown

Also Published As

Publication number	Publication date
HK1105199A1 (en)	2008-02-06
PT1753760E (en)	2008-02-12
ATE382619T1 (en)	2008-01-15
NZ550763A (en)	2010-07-30
AU2005247567A1 (en)	2005-12-08
EA200602048A1 (en)	2007-06-29
HRP20080027T3 (en)	2008-05-31
TNSN06371A1 (en)	2008-02-22
NO20065732L (en)	2006-12-22
CN1956983B (en)	2010-05-26
RS50574B (en)	2010-05-07
BRPI0511543A (en)	2008-01-02
US20050261289A1 (en)	2005-11-24
DE602005004142D1 (en)	2008-02-14
DOP2005000091A (en)	2005-06-29
CY1108104T1 (en)	2014-02-12
GT200500124A (en)	2005-12-26
JP4668265B2 (en)	2011-04-13
AU2005247567B2 (en)	2010-09-02
IL179364A (en)	2013-01-31
MA28601B1 (en)	2007-05-02
EP1753760B1 (en)	2008-01-02
SV2006002125A (en)	2006-02-15
ECSP067018A (en)	2006-12-29
DE602005004142T2 (en)	2009-01-02
SI1753760T1 (en)	2008-04-30
BRPI0511543B1 (en)	2022-05-10
AR048973A1 (en)	2006-06-14
HN2005000238A (en)	2008-07-14
EP1753760A1 (en)	2007-02-21
UA87142C2 (en)	2009-06-25
NO336939B1 (en)	2015-11-30
JP2008500295A (en)	2008-01-10
ES2297710T3 (en)	2008-05-01
CN1956983A (en)	2007-05-02
ZA200609136B (en)	2008-07-30
PL1753760T3 (en)	2008-06-30
PA8633901A1 (en)	2006-05-16
CA2567703A1 (en)	2005-12-08
TW200612937A (en)	2006-05-01
IL179364A0 (en)	2007-03-08
CA2567703C (en)	2013-03-05
TWI358297B (en)	2012-02-21
US7368446B2 (en)	2008-05-06
EA011279B1 (en)	2009-02-27
CR8703A (en)	2007-10-04
PE20060274A1 (en)	2006-04-14
MY140011A (en)	2009-11-30
WO2005116026A1 (en)	2005-12-08
MXPA06013417A (en)	2007-01-23

Publication	Publication Date	Title
ATE414693T1 (en)	2008-12-15	NOVEL CIS-IMIDAZOLINES
EP1741656A4 (en)	2009-12-02	ELEVATOR
EP1908719A4 (en)	2013-01-16	ELEVATOR
FI20041042L (en)	2006-01-31	Elevator
EP1852382A4 (en)	2013-01-30	ELEVATOR
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