DK1748791T3 - Neisseria Meningitidis IgtB LOS som hjælpestof - Google Patents

Neisseria Meningitidis IgtB LOS som hjælpestof

Info

Publication number: DK1748791T3
Authority: DK; Denmark
Prior art keywords: los; adjuvant; igtb; neisseria meningitidis; tri
Prior art date: 2004-05-11

Application number

DK05745670.9T

Other languages

English (en)

Inventor

Liana Juliana Josephine Steeghs

De Winkel Johannes Gerardus Joseph Van

Der Ley Peter Andre Van

Original Assignee

Staat Der Nederlanden Vert Doo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-05-11

Filing date

2005-05-11

Publication date

2010-06-28

2005-05-11 Application filed by Staat Der Nederlanden Vert Doo filed Critical Staat Der Nederlanden Vert Doo

2010-06-28 Application granted granted Critical

2010-06-28 Publication of DK1748791T3 publication Critical patent/DK1748791T3/da

Links

239000002671 adjuvant Substances 0.000 title abstract 2
241000588650 Neisseria meningitidis Species 0.000 title 1
241001212279 Neisseriales Species 0.000 abstract 2
150000004043 trisaccharides Chemical class 0.000 abstract 2
108010037897 DC-specific ICAM-3 grabbing nonintegrin Proteins 0.000 abstract 1
210000004443 dendritic cell Anatomy 0.000 abstract 1
230000003308 immunostimulating effect Effects 0.000 abstract 1
GZQKNULLWNGMCW-PWQABINMSA-N lipid A (E. coli) Chemical group O1[C@H](CO)[C@@H](OP(O)(O)=O)[C@H](OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)[C@@H](NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)[C@@H]1OC[C@@H]1[C@@H](O)[C@H](OC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](OP(O)(O)=O)O1 GZQKNULLWNGMCW-PWQABINMSA-N 0.000 abstract 1
150000002482 oligosaccharides Polymers 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
230000001988 toxicity Effects 0.000 abstract 1
231100000419 toxicity Toxicity 0.000 abstract 1
229960005486 vaccine Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Organic Chemistry (AREA)
Microbiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Mycology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Diaphragms For Electromechanical Transducers (AREA)
Amplifiers (AREA)
Medicinal Preparation (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Fats And Perfumes (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Soft Magnetic Materials (AREA)
Steroid Compounds (AREA)

DK05745670.9T 2004-05-11 2005-05-11 Neisseria Meningitidis IgtB LOS som hjælpestof DK1748791T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP04076401		2004-05-11
PCT/NL2005/000358 WO2005107798A1 (en)	2004-05-11	2005-05-11	NEISSERIA MENINGITIDIS IgtB LOS AS ADJUVANT

Publications (1)

Publication Number	Publication Date
DK1748791T3 true DK1748791T3 (da)	2010-06-28

Family

ID=34928212

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK05745670.9T DK1748791T3 (da)	2004-05-11	2005-05-11	Neisseria Meningitidis IgtB LOS som hjælpestof

Country Status (18)

Country	Link
US (1)	US20080138359A1 (da)
EP (1)	EP1748791B1 (da)
JP (1)	JP5174457B2 (da)
KR (1)	KR101270838B1 (da)
CN (1)	CN1997392B (da)
AT (1)	ATE464066T1 (da)
AU (1)	AU2005239963B2 (da)
BR (1)	BRPI0511026C1 (da)
CA (1)	CA2566409C (da)
DE (1)	DE602005020608D1 (da)
DK (1)	DK1748791T3 (da)
ES (1)	ES2344114T3 (da)
MX (1)	MXPA06013093A (da)
NZ (1)	NZ551250A (da)
PL (1)	PL1748791T3 (da)
PT (1)	PT1748791E (da)
SI (1)	SI1748791T1 (da)
WO (1)	WO2005107798A1 (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE9904581D0 (sv) *	1999-12-15	1999-12-15	A & Science Invest Ab	A novel helicobacter pylori-binding substance and use thereof
PL3017827T3 (pl)	2005-12-22	2019-04-30	Glaxosmithkline Biologicals Sa	Szczepionka z koniugatem polisacharydu pneumokokowego
GB0607088D0 (en)	2006-04-07	2006-05-17	Glaxosmithkline Biolog Sa	Vaccine
KR101541383B1 (ko)	2006-03-30	2015-08-03	글락소스미스클라인 바이오로지칼즈 에스.에이.	면역원성 조성물
US9610339B2 (en)	2007-06-26	2017-04-04	Glaxosmithkline Biologicals, S.A.	Vaccine comprising Streptococcus pneumoniae capsular polysaccharide conjugates
US8642046B2 (en) *	2007-10-09	2014-02-04	Tufts University	Cholera vaccines
US9387239B2 (en) *	2008-05-30	2016-07-12	U.S. Army Medical Research And Materiel Command	Meningococcal multivalent native outer membrane vesicle vaccine, methods of making and use thereof
EP2429576A1 (fr) *	2009-05-14	2012-03-21	Sanofi Pasteur	Vaccin meningocoque a base de lipooligosaccharide (los) et de proteine de neisseria meningitidis
WO2010130898A2 (fr)	2009-05-14	2010-11-18	Sanofi Pasteur	Vaccin meningocoque a base de lipooligosaccharide (los) provenant de souches modifiees de neisseria meningitidis d'immunotype l6
GB0913680D0 (en)	2009-08-05	2009-09-16	Glaxosmithkline Biolog Sa	Immunogenic composition
GB0913681D0 (en)	2009-08-05	2009-09-16	Glaxosmithkline Biolog Sa	Immunogenic composition
GB201003920D0 (en)	2010-03-09	2010-04-21	Glaxosmithkline Biolog Sa	Method of treatment
GB201003924D0 (en)	2010-03-09	2010-04-21	Glaxosmithkline Biolog Sa	Immunogenic composition
SG184188A1 (en)	2010-03-26	2012-10-30	Glaxosmithkline Biolog Sa	Hiv vaccine
KR20130139953A (ko)	2010-09-27	2013-12-23	글락소스미스클라인 바이오로지칼즈 에스.에이.	백신
KR20120068647A (ko) *	2010-12-18	2012-06-27	아이진 주식회사	개선된 면역반응을 유도하는 백신
CA2840096C (en)	2011-07-07	2021-07-06	Bas VAN DE WATERBEEMD	A process for detergent-free production of outer membrane vesicles of a gram-negative bacterium
GB201310008D0 (en)	2013-06-05	2013-07-17	Glaxosmithkline Biolog Sa	Immunogenic composition for use in therapy
US20170281744A1 (en)	2014-12-10	2017-10-05	Glaxosmithkline Biologicals Sa	Method of treatment
KR102002034B1 (ko)	2015-07-09	2019-07-22	에스에프씨주식회사	고효율과 장수명을 갖는 유기 발광 소자
JP7008901B2 (ja) *	2016-01-28	2022-01-25	イントラヴァックビー．ブイ．	改変されたヘキサアシル化ナイセリアｌｐｓ
EP3263695A1 (en)	2016-06-29	2018-01-03	GlaxoSmithKline Biologicals SA	Immunogenic compositions
US10918709B2 (en) *	2016-10-31	2021-02-16	Eyegene Inc.	Immune modulator and vaccine composition containing the same
US10973908B1 (en)	2020-05-14	2021-04-13	David Gordon Bermudes	Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL9101359A (nl) *	1991-08-07	1993-03-01	Nederlanden Staat	Nieuw saccharide-peptide-conjugaat, werkwijze ter bereiding ervan alsmede een vaccin dat een dergelijk saccharide-peptide-conjugaat omvat.
DK1127137T4 (da) *	1998-11-03	2014-02-10	Nederlanden Staat	LPS med reduceret toksicitet fra genetisk modificerede gram-negative bakterier
GB0103170D0 (en) *	2001-02-08	2001-03-28	Smithkline Beecham Biolog	Vaccine composition
EP1423142A1 (en) *	2001-08-31	2004-06-02	Chiron SRL.	Helicobacter pylori vaccination with a combination of caga, vaca and nap proteins
DK2255826T3 (da) *	2002-08-02	2016-06-20	Glaxosmithkline Biologicals Sa	Neisseria-vaccinesammensætninger omfattende en kombination af antigener.
US20090246224A1 (en) *	2006-06-12	2009-10-01	Nathalie Devos	Vaccine

2005
- 2005-05-11 CN CN2005800181701A patent/CN1997392B/zh not_active Expired - Fee Related
- 2005-05-11 EP EP05745670A patent/EP1748791B1/en not_active Expired - Lifetime
- 2005-05-11 KR KR1020067026018A patent/KR101270838B1/ko not_active Expired - Fee Related
- 2005-05-11 WO PCT/NL2005/000358 patent/WO2005107798A1/en not_active Ceased
- 2005-05-11 SI SI200531025T patent/SI1748791T1/sl unknown
- 2005-05-11 DE DE602005020608T patent/DE602005020608D1/de not_active Expired - Lifetime
- 2005-05-11 JP JP2007513087A patent/JP5174457B2/ja not_active Expired - Fee Related
- 2005-05-11 AU AU2005239963A patent/AU2005239963B2/en not_active Ceased
- 2005-05-11 PT PT05745670T patent/PT1748791E/pt unknown
- 2005-05-11 MX MXPA06013093A patent/MXPA06013093A/es active IP Right Grant
- 2005-05-11 BR BRPI0511026A patent/BRPI0511026C1/pt not_active IP Right Cessation
- 2005-05-11 AT AT05745670T patent/ATE464066T1/de active
- 2005-05-11 ES ES05745670T patent/ES2344114T3/es not_active Expired - Lifetime
- 2005-05-11 DK DK05745670.9T patent/DK1748791T3/da active
- 2005-05-11 PL PL05745670T patent/PL1748791T3/pl unknown
- 2005-05-11 NZ NZ551250A patent/NZ551250A/en not_active IP Right Cessation
- 2005-05-11 CA CA2566409A patent/CA2566409C/en not_active Expired - Fee Related
- 2005-05-11 US US11/596,319 patent/US20080138359A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CA2566409C (en)	2012-12-04
BRPI0511026C1 (pt)	2021-05-25
SI1748791T1 (sl)	2010-07-30
CA2566409A1 (en)	2005-11-17
KR101270838B1 (ko)	2013-07-04
KR20070029742A (ko)	2007-03-14
PL1748791T3 (pl)	2010-08-31
ATE464066T1 (de)	2010-04-15
EP1748791A1 (en)	2007-02-07
EP1748791B1 (en)	2010-04-14
US20080138359A1 (en)	2008-06-12
NZ551250A (en)	2010-03-26
CN1997392B (zh)	2011-06-01
DE602005020608D1 (de)	2010-05-27
BRPI0511026B1 (pt)	2019-01-08
BRPI0511026A (pt)	2007-11-27
PT1748791E (pt)	2010-07-15
AU2005239963B2 (en)	2011-01-06
JP5174457B2 (ja)	2013-04-03
MXPA06013093A (es)	2007-08-08
JP2007537248A (ja)	2007-12-20
ES2344114T3 (es)	2010-08-18
CN1997392A (zh)	2007-07-11
AU2005239963A1 (en)	2005-11-17
WO2005107798A1 (en)	2005-11-17
BRPI0511026B8 (pt)	2020-01-21

Publication	Publication Date	Title
DK1748791T3 (da)	2010-06-28	Neisseria Meningitidis IgtB LOS som hjælpestof
MX393384B (es)	2025-03-24	Adyuvantes sinteticos de glucopiranosil-lipido.
BRPI0409133A (pt)	2006-05-02	formulações farmacêuticas contendo metilnaltrexona
WO2006012209A3 (en)	2007-03-22	A new adjuvant composition
MX2010012999A (es)	2012-03-07	Vacuna de vesícula de membrana externa nativa multivalente del meningococo, método para su fabricación y uso.
AU2457100A (en)	2000-09-14	Enhancement of bactericidal activity of neisseria antigens with oligonucleotidescontaining cg motifs
FR11C0001I2 (fr)	2017-05-19	Vaccins combines contre neisseria meningitidis
NO20074908L (no)	2007-12-27	Preparater inneholdende fettsyrer og/eller derivater derav og et lavtemperatur-stabiliseringsmiddel
PT1187629E (pt)	2005-02-28	Composicao adjuvante que compreende saponina e um oligonucleotido imunoestimulador
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CY1109582T1 (el)	2014-08-13	Συνδυασμενα μηνιγγοκοκκινα συζευγματα με κοινη πρωτεϊνη φορεα
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BR0015961A (pt)	2003-06-10	Antìgeno de neisseria de 85kda
WO2005097211A3 (en)	2007-03-29	Compositions as adjuvants to improve immune responses to vaccines and methods of use
DE60303961D1 (de)	2006-05-04	Modifizierte saccharide, deren konjugate sowie deren herstellung
DK1506185T3 (da)	2006-10-02	Forbindelser og deres anvendelse som 5-HT-inhibitorer
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EA200701128A1 (ru)	2008-02-28	Рекомбинантные штаммы bcg, обладающие повышенной способностью к высвобождению из эндосомы
DK1469843T3 (da)	2007-11-05	Komposition til farmaceutisk eller diætetisk anvendelse til at bekæmpe hårtab
AR049681A1 (es)	2006-08-30	Macrolidos preparados a partir de actinomicetos. composiciones farmaceuticas
WO2005120564A3 (en)	2007-11-15	Vaccine compositions and methods
EA200701172A1 (ru)	2007-10-26	2-алкокси-3,4,5-тригидроксиалкиламиды, их получение, композиции, их содержащие, и применение
BRPI0412239A (pt)	2006-09-12	sistemas emulsificantes contendo derivados de azetidina