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DK1681299T3 - Fremgangsmåde til rensning af højt anioniske proteiner - Google Patents

Fremgangsmåde til rensning af højt anioniske proteiner

Info

Publication number
DK1681299T3
DK1681299T3 DK06006740.2T DK06006740T DK1681299T3 DK 1681299 T3 DK1681299 T3 DK 1681299T3 DK 06006740 T DK06006740 T DK 06006740T DK 1681299 T3 DK1681299 T3 DK 1681299T3
Authority
DK
Denmark
Prior art keywords
purification
proteins
highly anionic
sulfations
sulfated
Prior art date
Application number
DK06006740.2T
Other languages
English (en)
Inventor
Jonathan L Coffman
William Barry Foster
Bonnie J Germain
Shujun Sun
Jeffrey J Robinson
Original Assignee
Genetics Inst Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Inst Llc filed Critical Genetics Inst Llc
Application granted granted Critical
Publication of DK1681299T3 publication Critical patent/DK1681299T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/20Partition-, reverse-phase or hydrophobic interaction chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/36Extraction; Separation; Purification by a combination of two or more processes of different types
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596Molecules with a "CD"-designation not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
DK06006740.2T 2000-03-27 2001-03-27 Fremgangsmåde til rensning af højt anioniske proteiner DK1681299T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19335100P 2000-03-27 2000-03-27
EP01922750A EP1268514B1 (en) 2000-03-27 2001-03-27 Methods for purifying highly anionic proteins

Publications (1)

Publication Number Publication Date
DK1681299T3 true DK1681299T3 (da) 2010-02-01

Family

ID=22713294

Family Applications (3)

Application Number Title Priority Date Filing Date
DK06006739.4T DK1681298T3 (da) 2000-03-27 2001-03-27 Fremgangsmåder til oprensning af særdeles anioniske proteiner
DK06006740.2T DK1681299T3 (da) 2000-03-27 2001-03-27 Fremgangsmåde til rensning af højt anioniske proteiner
DK01922750T DK1268514T3 (da) 2000-03-27 2001-03-27 Fremgangsmåde til oprensning af særdeles anioniske proteiner

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK06006739.4T DK1681298T3 (da) 2000-03-27 2001-03-27 Fremgangsmåder til oprensning af særdeles anioniske proteiner

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK01922750T DK1268514T3 (da) 2000-03-27 2001-03-27 Fremgangsmåde til oprensning af særdeles anioniske proteiner

Country Status (11)

Country Link
US (1) US6933370B2 (da)
EP (3) EP1681299B1 (da)
JP (2) JP5025874B2 (da)
AT (3) ATE448241T1 (da)
AU (2) AU2001249515B2 (da)
CA (1) CA2404155C (da)
DE (3) DE60120374T2 (da)
DK (3) DK1681298T3 (da)
ES (3) ES2338687T3 (da)
NZ (1) NZ521578A (da)
WO (1) WO2001072769A2 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1714982T3 (da) * 2001-06-05 2009-05-04 Genetics Inst Llc Fremgangsmåde til rensning af stærkt anioniske proteiner
AU2003233008B2 (en) * 2002-04-22 2008-04-24 Recopharma Ab Fusion polypeptides and methods for inhibiting microbial adhesion
ATE462716T1 (de) * 2003-10-24 2010-04-15 Amgen Inc Verfahren zur aufreinigung von proteinen in einer durchflussfraktion aus der chromatographie mit hydrophoben wechselwirkungen
US7651690B2 (en) * 2005-06-24 2010-01-26 Desert Lake Technologies Purified component of blue-green algae and method of use
TWI423986B (zh) * 2005-12-20 2014-01-21 必治妥美雅史谷比公司 組合物及製造組合物之方法
AR058568A1 (es) 2005-12-20 2008-02-13 Bristol Myers Squibb Co Metodos para producir una composicion con moleculas ctla4-ig a partir de un medio de cultivo
US8853371B2 (en) 2006-10-19 2014-10-07 Janssen Biotech, Inc. Process for preparing unaggregated antibody Fc domains
US20130116413A1 (en) * 2009-12-29 2013-05-09 Dr. Reddy's Laboratories, Inc. Purification of proteins
EA201201132A1 (ru) * 2010-02-12 2013-03-29 ДСМ АйПи АССЕТС Б.В. Очистка антител с помощью единого функционального блока
CA2812058C (en) * 2010-09-20 2019-04-16 Bio-Rad Laboratories, Inc. Dissociation of product-complexed contaminants in chromatography
KR102617873B1 (ko) * 2016-10-28 2023-12-22 머크 샤프 앤드 돔 엘엘씨 티로신 황산화 항체 변이체의 제거를 위한 정제 프로세스, 정제된 조성물
EP3580231A1 (en) * 2017-02-09 2019-12-18 Bracco Suisse SA Process for the purification of soluble psgl-1 protein variants
US11447547B1 (en) 2017-12-13 2022-09-20 Amgen Inc. Method of antigen-binding protein production
US20230331773A1 (en) * 2022-04-15 2023-10-19 Pall Corporation Chromatography device and method of use

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4723000A (en) * 1983-07-05 1988-02-02 Biospectrum, Inc. Human interferon gamma and interleukin-2
US5115101A (en) 1988-06-08 1992-05-19 Miles Inc. Removal of protein A from antibody preparations
US5378464A (en) * 1989-03-08 1995-01-03 Board Of Regents Of The University Of Oklahoma Modulation of inflammatory responses by administration of GMP-140 or antibody to GMP-140
US5464778A (en) * 1989-03-08 1995-11-07 Board Of Regents Of The University Of Oklahoma Glycoprotein ligand for P-selectin and methods of use thereof
US5034133A (en) * 1990-07-26 1991-07-23 Schering-Corporation Purification of human interleukin-4 from a CHO-cell line culture medium
US5530109A (en) * 1991-04-10 1996-06-25 Ludwig Institute For Cancer Research DNA encoding glial mitogenic factors
US6277975B1 (en) * 1992-10-23 2001-08-21 Genetics Institute, Inc. Fusions of P-selectin ligand protein and polynucleotides encoding same
JPH08502886A (ja) * 1992-10-23 1996-04-02 ジェネティックス・インスティテュート・インコーポレイテッド 新規p−セレクチンリガンド蛋白質
US5843707A (en) 1992-10-23 1998-12-01 Genetics Institute, Inc. Nucleic acid encoding a novel P-selectin ligand protein
US5429746A (en) 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
EP1104809A1 (en) * 1994-04-09 2001-06-06 F. Hoffmann-La Roche Ag Process for producing alpha-interferon
US6008328A (en) 1994-10-13 1999-12-28 Amgen Inc. Method for purifying keratinocyte growth factors
SE503424C2 (sv) 1994-11-14 1996-06-10 Pharmacia Ab Process för rening av rekombinant koagulationsfaktor VIII
FR2737730B1 (fr) 1995-08-10 1997-09-05 Pasteur Merieux Serums Vacc Procede de purification de virus par chromatographie
FR2738009B1 (fr) 1995-08-24 1997-10-31 Centre Nat Rech Scient Procede d'obtention de polysaccharides sulfates
JP4671372B2 (ja) 1996-11-15 2011-04-13 ジェネンテック, インコーポレイテッド ニューロトロフィンの精製
WO1999019345A1 (en) * 1997-10-14 1999-04-22 Institute For Vaccine Development Method for purifying retroviral particles and soluble viral antigens

Also Published As

Publication number Publication date
US6933370B2 (en) 2005-08-23
DE60140493D1 (de) 2009-12-24
EP1681299A2 (en) 2006-07-19
DE60141657D1 (de) 2010-05-06
ATE461935T1 (de) 2010-04-15
ATE448241T1 (de) 2009-11-15
JP5025874B2 (ja) 2012-09-12
JP2012184245A (ja) 2012-09-27
ATE328895T1 (de) 2006-06-15
EP1268514B1 (en) 2006-06-07
EP1681299A3 (en) 2006-12-27
ES2343023T3 (es) 2010-07-21
DK1681298T3 (da) 2010-06-14
DE60120374T2 (de) 2007-06-06
EP1681298A2 (en) 2006-07-19
JP2003528884A (ja) 2003-09-30
CA2404155C (en) 2011-08-09
DE60120374D1 (de) 2006-07-20
ES2338687T3 (es) 2010-05-11
AU2001249515B2 (en) 2006-10-05
DK1268514T3 (da) 2006-10-09
WO2001072769A2 (en) 2001-10-04
AU4951501A (en) 2001-10-08
US20020132991A1 (en) 2002-09-19
EP1268514A2 (en) 2003-01-02
JP5596078B2 (ja) 2014-09-24
ES2266188T3 (es) 2007-03-01
EP1681298B1 (en) 2010-03-24
EP1681299B1 (en) 2009-11-11
NZ521578A (en) 2004-08-27
WO2001072769A9 (en) 2003-04-03
EP1681298A3 (en) 2006-12-20
WO2001072769A3 (en) 2002-02-07
CA2404155A1 (en) 2001-10-04

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