DK167716B1 - Mikroelektrode til elektrokemisk analyse - Google Patents

Mikroelektrode til elektrokemisk analyse Download PDF

Info

Publication number: DK167716B1
Authority: DK; Denmark
Prior art keywords: electrode; resin; carbon fibers; micro electrode; membrane
Prior art date: 1986-04-22

Application number

DK673187A

Other languages

Danish (da)

English (en)

Other versions

DK673187D0 (da

DK673187A (da

Inventor

Kenichi Morita

Yoshihiro Shimizu

Original Assignee

Toray Industries

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-04-22

Filing date

1987-12-21

Publication date

1993-12-06

1987-12-21 Application filed by Toray Industries filed Critical Toray Industries

1987-12-21 Publication of DK673187D0 publication Critical patent/DK673187D0/da

1987-12-22 Publication of DK673187A publication Critical patent/DK673187A/da

1993-12-06 Application granted granted Critical

1993-12-06 Publication of DK167716B1 publication Critical patent/DK167716B1/da

Links

238000000840 electrochemical analysis Methods 0.000 title claims description 4
229920000049 Carbon (fiber) Polymers 0.000 claims description 46
239000004917 carbon fiber Substances 0.000 claims description 46
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 33
239000001301 oxygen Substances 0.000 claims description 33
229910052760 oxygen Inorganic materials 0.000 claims description 33
239000012528 membrane Substances 0.000 claims description 28
229920005989 resin Polymers 0.000 claims description 19
239000011347 resin Substances 0.000 claims description 19
229910052709 silver Inorganic materials 0.000 claims description 14
239000004332 silver Substances 0.000 claims description 14
BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims description 13
239000000835 fiber Substances 0.000 claims description 10
-1 silver silver halide Chemical class 0.000 claims description 10
102000004190 Enzymes Human genes 0.000 claims description 9
108090000790 Enzymes Proteins 0.000 claims description 9
239000003822 epoxy resin Substances 0.000 claims description 8
229920000647 polyepoxide Polymers 0.000 claims description 8
244000005700 microbiome Species 0.000 claims description 5
239000011159 matrix material Substances 0.000 claims description 4
239000005011 phenolic resin Substances 0.000 claims description 3
239000004721 Polyphenylene oxide Substances 0.000 claims description 2
239000004734 Polyphenylene sulfide Substances 0.000 claims description 2
BZHJMEDXRYGGRV-UHFFFAOYSA-N Vinyl chloride Chemical compound ClC=C BZHJMEDXRYGGRV-UHFFFAOYSA-N 0.000 claims description 2
GPRLSGONYQIRFK-UHFFFAOYSA-N hydron Chemical compound [H+] GPRLSGONYQIRFK-UHFFFAOYSA-N 0.000 claims description 2
229920001225 polyester resin Polymers 0.000 claims description 2
239000004645 polyester resin Substances 0.000 claims description 2
229920006380 polyphenylene oxide Polymers 0.000 claims description 2
229920000069 polyphenylene sulfide Polymers 0.000 claims description 2
229920002050 silicone resin Polymers 0.000 claims description 2
229920002803 thermoplastic polyurethane Polymers 0.000 claims description 2
BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 39
239000000243 solution Substances 0.000 description 20
238000000034 method Methods 0.000 description 18
VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 description 17
229910052697 platinum Inorganic materials 0.000 description 17
238000006722 reduction reaction Methods 0.000 description 17
230000003647 oxidation Effects 0.000 description 13
238000007254 oxidation reaction Methods 0.000 description 13
QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 12
239000000463 material Substances 0.000 description 12
238000011109 contamination Methods 0.000 description 10
WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 9
239000002131 composite material Substances 0.000 description 9
PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical compound NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 description 8
239000002585 base Substances 0.000 description 8
229940088598 enzyme Drugs 0.000 description 8
229910021607 Silver chloride Inorganic materials 0.000 description 7
238000006116 polymerization reaction Methods 0.000 description 7
HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 description 7
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
150000002500 ions Chemical class 0.000 description 6
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 5
230000000052 comparative effect Effects 0.000 description 5
ZOMNIUBKTOKEHS-UHFFFAOYSA-L dimercury dichloride Chemical class Cl[Hg][Hg]Cl ZOMNIUBKTOKEHS-UHFFFAOYSA-L 0.000 description 5
239000001257 hydrogen Substances 0.000 description 5
229910052739 hydrogen Inorganic materials 0.000 description 5
239000008055 phosphate buffer solution Substances 0.000 description 5
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
NXXYKOUNUYWIHA-UHFFFAOYSA-N 2,6-Dimethylphenol Chemical compound CC1=CC=CC(C)=C1O NXXYKOUNUYWIHA-UHFFFAOYSA-N 0.000 description 4
239000004366 Glucose oxidase Substances 0.000 description 4
108010015776 Glucose oxidase Proteins 0.000 description 4
MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 4
229910052799 carbon Inorganic materials 0.000 description 4
239000008367 deionised water Substances 0.000 description 4
229910021641 deionized water Inorganic materials 0.000 description 4
238000000855 fermentation Methods 0.000 description 4
230000004151 fermentation Effects 0.000 description 4
229940116332 glucose oxidase Drugs 0.000 description 4
235000019420 glucose oxidase Nutrition 0.000 description 4
238000007747 plating Methods 0.000 description 4
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 3
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 3
238000005842 biochemical reaction Methods 0.000 description 3
210000001124 body fluid Anatomy 0.000 description 3
239000010839 body fluid Substances 0.000 description 3
239000003795 chemical substances by application Substances 0.000 description 3
238000001723 curing Methods 0.000 description 3
239000010411 electrocatalyst Substances 0.000 description 3
238000003487 electrochemical reaction Methods 0.000 description 3
238000005530 etching Methods 0.000 description 3
239000008103 glucose Substances 0.000 description 3
229920000642 polymer Polymers 0.000 description 3
238000002360 preparation method Methods 0.000 description 3
BAZAXWOYCMUHIX-UHFFFAOYSA-M sodium perchlorate Chemical compound [Na+].[O-]Cl(=O)(=O)=O BAZAXWOYCMUHIX-UHFFFAOYSA-M 0.000 description 3
229910001488 sodium perchlorate Inorganic materials 0.000 description 3
230000001954 sterilising effect Effects 0.000 description 3
238000004659 sterilization and disinfection Methods 0.000 description 3
YZVWKHVRBDQPMQ-UHFFFAOYSA-N 1-aminopyrene Chemical compound C1=C2C(N)=CC=C(C=C3)C2=C2C3=CC=CC2=C1 YZVWKHVRBDQPMQ-UHFFFAOYSA-N 0.000 description 2
NKTOLZVEWDHZMU-UHFFFAOYSA-N 2,5-xylenol Chemical compound CC1=CC=C(C)C(O)=C1 NKTOLZVEWDHZMU-UHFFFAOYSA-N 0.000 description 2
HLBLWEWZXPIGSM-UHFFFAOYSA-N 4-Aminophenyl ether Chemical compound C1=CC(N)=CC=C1OC1=CC=C(N)C=C1 HLBLWEWZXPIGSM-UHFFFAOYSA-N 0.000 description 2
QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
241001391944 Commicarpus scandens Species 0.000 description 2
229910001111 Fine metal Inorganic materials 0.000 description 2
ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 2
JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 2
150000001413 amino acids Chemical class 0.000 description 2
238000004082 amperometric method Methods 0.000 description 2
238000004458 analytical method Methods 0.000 description 2
239000007864 aqueous solution Substances 0.000 description 2
150000001720 carbohydrates Chemical class 0.000 description 2
150000001875 compounds Chemical class 0.000 description 2
239000007789 gas Substances 0.000 description 2
239000000499 gel Substances 0.000 description 2
239000011521 glass Substances 0.000 description 2
229910052736 halogen Inorganic materials 0.000 description 2
238000010438 heat treatment Methods 0.000 description 2
230000002452 interceptive effect Effects 0.000 description 2
JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
239000000178 monomer Substances 0.000 description 2
239000012811 non-conductive material Substances 0.000 description 2
230000035699 permeability Effects 0.000 description 2
229920002401 polyacrylamide Polymers 0.000 description 2
239000004800 polyvinyl chloride Substances 0.000 description 2
229920000915 polyvinyl chloride Polymers 0.000 description 2
238000004313 potentiometry Methods 0.000 description 2
230000002829 reductive effect Effects 0.000 description 2
230000035945 sensitivity Effects 0.000 description 2
239000000126 substance Substances 0.000 description 2
239000003115 supporting electrolyte Substances 0.000 description 2
GEYOCULIXLDCMW-UHFFFAOYSA-N 1,2-phenylenediamine Chemical compound NC1=CC=CC=C1N GEYOCULIXLDCMW-UHFFFAOYSA-N 0.000 description 1
YFOOEYJGMMJJLS-UHFFFAOYSA-N 1,8-diaminonaphthalene Chemical compound C1=CC(N)=C2C(N)=CC=CC2=C1 YFOOEYJGMMJJLS-UHFFFAOYSA-N 0.000 description 1
ICNFHJVPAJKPHW-UHFFFAOYSA-N 4,4'-Thiodianiline Chemical compound C1=CC(N)=CC=C1SC1=CC=C(N)C=C1 ICNFHJVPAJKPHW-UHFFFAOYSA-N 0.000 description 1
229920001817 Agar Polymers 0.000 description 1
239000004254 Ammonium phosphate Substances 0.000 description 1
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 1
229920002284 Cellulose triacetate Polymers 0.000 description 1
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 1
108010010803 Gelatin Proteins 0.000 description 1
SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 1
108010008292 L-Amino Acid Oxidase Proteins 0.000 description 1
102000007070 L-amino-acid oxidase Human genes 0.000 description 1
108010073450 Lactate 2-monooxygenase Proteins 0.000 description 1
102000004882 Lipase Human genes 0.000 description 1
108090001060 Lipase Proteins 0.000 description 1
239000004367 Lipase Substances 0.000 description 1
239000004677 Nylon Substances 0.000 description 1
108090000854 Oxidoreductases Proteins 0.000 description 1
102000004316 Oxidoreductases Human genes 0.000 description 1
108010087702 Penicillinase Proteins 0.000 description 1
239000004698 Polyethylene Substances 0.000 description 1
239000004372 Polyvinyl alcohol Substances 0.000 description 1
108010042687 Pyruvate Oxidase Proteins 0.000 description 1
229920000297 Rayon Polymers 0.000 description 1
PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
108010064129 Thrombogen Proteins 0.000 description 1
ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 1
108010046334 Urease Proteins 0.000 description 1
LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 1
TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 1
SMEGJBVQLJJKKX-HOTMZDKISA-N [(2R,3S,4S,5R,6R)-5-acetyloxy-3,4,6-trihydroxyoxan-2-yl]methyl acetate Chemical compound CC(=O)OC[C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)OC(=O)C)O)O SMEGJBVQLJJKKX-HOTMZDKISA-N 0.000 description 1
NNLVGZFZQQXQNW-ADJNRHBOSA-N [(2r,3r,4s,5r,6s)-4,5-diacetyloxy-3-[(2s,3r,4s,5r,6r)-3,4,5-triacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6s)-4,5,6-triacetyloxy-2-(acetyloxymethyl)oxan-3-yl]oxyoxan-2-yl]methyl acetate Chemical compound O([C@@H]1O[C@@H]([C@H]([C@H](OC(C)=O)[C@H]1OC(C)=O)O[C@H]1[C@@H]([C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O1)OC(C)=O)COC(=O)C)[C@@H]1[C@@H](COC(C)=O)O[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O NNLVGZFZQQXQNW-ADJNRHBOSA-N 0.000 description 1
229940081735 acetylcellulose Drugs 0.000 description 1
239000002253 acid Substances 0.000 description 1
239000003929 acidic solution Substances 0.000 description 1
230000002378 acidificating effect Effects 0.000 description 1
239000008272 agar Substances 0.000 description 1
150000001298 alcohols Chemical class 0.000 description 1
239000012670 alkaline solution Substances 0.000 description 1
125000003277 amino group Chemical group 0.000 description 1
229910021529 ammonia Inorganic materials 0.000 description 1
229910000148 ammonium phosphate Inorganic materials 0.000 description 1
235000019289 ammonium phosphates Nutrition 0.000 description 1
150000001448 anilines Chemical class 0.000 description 1
239000000427 antigen Substances 0.000 description 1
102000036639 antigens Human genes 0.000 description 1
108091007433 antigens Proteins 0.000 description 1
150000001491 aromatic compounds Chemical class 0.000 description 1
239000003637 basic solution Substances 0.000 description 1
235000021028 berry Nutrition 0.000 description 1
VCCBEIPGXKNHFW-UHFFFAOYSA-N biphenyl-4,4'-diol Chemical compound C1=CC(O)=CC=C1C1=CC=C(O)C=C1 VCCBEIPGXKNHFW-UHFFFAOYSA-N 0.000 description 1
239000008280 blood Substances 0.000 description 1
210000004369 blood Anatomy 0.000 description 1
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 1
229910052794 bromium Inorganic materials 0.000 description 1
229940041514 candida albicans extract Drugs 0.000 description 1
239000001569 carbon dioxide Substances 0.000 description 1
229910002092 carbon dioxide Inorganic materials 0.000 description 1
239000003518 caustics Substances 0.000 description 1
229920002301 cellulose acetate Polymers 0.000 description 1
238000006243 chemical reaction Methods 0.000 description 1
229910052801 chlorine Inorganic materials 0.000 description 1
239000000460 chlorine Substances 0.000 description 1
239000011248 coating agent Substances 0.000 description 1
238000000576 coating method Methods 0.000 description 1
238000010276 construction Methods 0.000 description 1
238000007796 conventional method Methods 0.000 description 1
238000004132 cross linking Methods 0.000 description 1
239000012531 culture fluid Substances 0.000 description 1
230000003247 decreasing effect Effects 0.000 description 1
MNNHAPBLZZVQHP-UHFFFAOYSA-N diammonium hydrogen phosphate Chemical compound [NH4+].[NH4+].OP([O-])([O-])=O MNNHAPBLZZVQHP-UHFFFAOYSA-N 0.000 description 1
238000006073 displacement reaction Methods 0.000 description 1
230000000694 effects Effects 0.000 description 1
239000011263 electroactive material Substances 0.000 description 1
238000002848 electrochemical method Methods 0.000 description 1
239000003792 electrolyte Substances 0.000 description 1
239000008151 electrolyte solution Substances 0.000 description 1
238000006056 electrooxidation reaction Methods 0.000 description 1
125000000524 functional group Chemical group 0.000 description 1
229920000159 gelatin Polymers 0.000 description 1
239000008273 gelatin Substances 0.000 description 1
235000019322 gelatine Nutrition 0.000 description 1
235000011852 gelatine desserts Nutrition 0.000 description 1
PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
229910052737 gold Inorganic materials 0.000 description 1
239000010931 gold Substances 0.000 description 1
229910002804 graphite Inorganic materials 0.000 description 1
239000010439 graphite Substances 0.000 description 1
150000002367 halogens Chemical class 0.000 description 1
238000013007 heat curing Methods 0.000 description 1
230000000642 iatrogenic effect Effects 0.000 description 1
229910052741 iridium Inorganic materials 0.000 description 1
GKOZUEZYRPOHIO-UHFFFAOYSA-N iridium atom Chemical compound [Ir] GKOZUEZYRPOHIO-UHFFFAOYSA-N 0.000 description 1
239000004310 lactic acid Substances 0.000 description 1
235000014655 lactic acid Nutrition 0.000 description 1
235000019421 lipase Nutrition 0.000 description 1
229940040461 lipase Drugs 0.000 description 1
238000012423 maintenance Methods 0.000 description 1
206010025482 malaise Diseases 0.000 description 1
238000005259 measurement Methods 0.000 description 1
229910052751 metal Inorganic materials 0.000 description 1
239000002184 metal Substances 0.000 description 1
239000000203 mixture Substances 0.000 description 1
KQSABULTKYLFEV-UHFFFAOYSA-N naphthalene-1,5-diamine Chemical compound C1=CC=C2C(N)=CC=CC2=C1N KQSABULTKYLFEV-UHFFFAOYSA-N 0.000 description 1
230000007935 neutral effect Effects 0.000 description 1
229920001778 nylon Polymers 0.000 description 1
239000003960 organic solvent Substances 0.000 description 1
230000001590 oxidative effect Effects 0.000 description 1
230000036961 partial effect Effects 0.000 description 1
229950009506 penicillinase Drugs 0.000 description 1
150000002989 phenols Chemical class 0.000 description 1
IEQIEDJGQAUEQZ-UHFFFAOYSA-N phthalocyanine Chemical compound N1C(N=C2C3=CC=CC=C3C(N=C3C4=CC=CC=C4C(=N4)N3)=N2)=C(C=CC=C2)C2=C1N=C1C2=CC=CC=C2C4=N1 IEQIEDJGQAUEQZ-UHFFFAOYSA-N 0.000 description 1
229920002239 polyacrylonitrile Polymers 0.000 description 1
229920000767 polyaniline Polymers 0.000 description 1
229920000573 polyethylene Polymers 0.000 description 1
229920005597 polymer membrane Polymers 0.000 description 1
229920001343 polytetrafluoroethylene Polymers 0.000 description 1
239000004810 polytetrafluoroethylene Substances 0.000 description 1
229920002451 polyvinyl alcohol Polymers 0.000 description 1
239000011148 porous material Substances 0.000 description 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
MFUFBSLEAGDECJ-UHFFFAOYSA-N pyren-2-ylamine Natural products C1=CC=C2C=CC3=CC(N)=CC4=CC=C1C2=C43 MFUFBSLEAGDECJ-UHFFFAOYSA-N 0.000 description 1
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
239000002964 rayon Substances 0.000 description 1
239000000376 reactant Substances 0.000 description 1
230000002441 reversible effect Effects 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
239000012488 sample solution Substances 0.000 description 1
229920006395 saturated elastomer Polymers 0.000 description 1
239000001488 sodium phosphate Substances 0.000 description 1
229910000162 sodium phosphate Inorganic materials 0.000 description 1
229910052938 sodium sulfate Inorganic materials 0.000 description 1
235000011152 sodium sulphate Nutrition 0.000 description 1
238000001179 sorption measurement Methods 0.000 description 1
238000005507 spraying Methods 0.000 description 1
RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
229940116269 uric acid Drugs 0.000 description 1
238000007738 vacuum evaporation Methods 0.000 description 1
238000007740 vapor deposition Methods 0.000 description 1
239000012138 yeast extract Substances 0.000 description 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/308—Electrodes, e.g. test electrodes; Half-cells at least partially made of carbon
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Electrochemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Molecular Biology (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Immunology (AREA)
Pathology (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Inert Electrodes (AREA)
Electrodes For Compound Or Non-Metal Manufacture (AREA)

DK673187A 1986-04-22 1987-12-21 Mikroelektrode til elektrokemisk analyse DK167716B1 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP9267686		1986-04-22
JP9267686		1986-04-22
PCT/JP1987/000252 WO1987006701A1 (fr)	1986-04-22	1987-04-21	Micro-electrode pour analyses electrochimiques
JP8700252		1987-04-21

Publications (3)

Publication Number	Publication Date
DK673187D0 DK673187D0 (da)	1987-12-21
DK673187A DK673187A (da)	1987-12-22
DK167716B1 true DK167716B1 (da)	1993-12-06

Family

ID=14061085

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK673187A DK167716B1 (da)	1986-04-22	1987-12-21	Mikroelektrode til elektrokemisk analyse

Country Status (5)

Country	Link
US (1)	US4908115A (ja)
EP (1)	EP0266432B1 (ja)
DE (1)	DE3776081D1 (ja)
DK (1)	DK167716B1 (ja)
WO (1)	WO1987006701A1 (ja)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8729002D0 (en) *	1987-12-11	1988-01-27	Iq Bio Ltd	Electrode material
DE3816458A1 (de) *	1988-05-13	1989-12-21	Josowicz Mira	Ultramikroelektrode, verfahren zu deren herstellung und ihre verwendung
GB8924338D0 (en) *	1989-10-28	1989-12-13	Atomic Energy Authority Uk	Electrodes
GB8927377D0 (en) *	1989-12-04	1990-01-31	Univ Edinburgh	Improvements in and relating to amperometric assays
SE468179B (sv) *	1990-05-09	1992-11-16	Sensistor Ab	Elektrokemisk maetelektrod och foerfarande foer framstaellning av maetelektroden
JP2816262B2 (ja) *	1991-07-09	1998-10-27	工業技術院長	炭素微小センサー電極およびその製造方法
WO1995004928A1 (en) *	1993-08-11	1995-02-16	Commonwealth Scientific And Industrial Research Organisation	A microelectrode assembly
JPH08508575A (ja) *	1994-01-25	1996-09-10	ケメロヴスキ・ゴスダルストヴェニ・ユニヴィルシテット	電極システム及び該システムを用いた電解電量分析による物質の試験装置
EP0767372A1 (de) *	1995-10-06	1997-04-09	Metrohm Ag	Ionenselektive Elektrode
US5955887A (en) *	1995-12-22	1999-09-21	The B. F. Goodrich Company	Impedance type ice detector
DE19653436C1 (de) *	1996-12-20	1998-08-13	Inst Chemo Biosensorik	Elektrochemischer Sensor
AU1343499A (en) *	1997-12-05	1999-06-28	Victoria University Of Manchester, The	Sensor devices and methods for using them
GB9809918D0 (en)	1998-05-08	1998-07-08	Isis Innovation	Microelectrode biosensor and method therefor
JP3632558B2 (ja) *	1999-09-17	2005-03-23	日立化成工業株式会社	封止用エポキシ樹脂組成物及び電子部品装置
WO2001025474A2 (en) *	1999-10-07	2001-04-12	Pepex Biomedical, Llc	Sensor for measuring a bioanalyte such as lactate
US7723099B2 (en) *	2003-09-10	2010-05-25	Abbott Point Of Care Inc.	Immunoassay device with immuno-reference electrode
DE202006020462U1 (de)	2006-11-22	2008-09-18	Dräger Safety AG & Co. KGaA	Elektrochemischer Gassensor mit zumindest einer punktförmigen Messelektrode
US20080138663A1 (en) *	2006-12-12	2008-06-12	Canon Kabushiki Kaisha	Microbial electrode and fuel cell and sensor using the same
WO2009032760A2 (en)	2007-08-30	2009-03-12	Pepex Biomedical Llc	Electrochmical sensor and method for manufacturing
US9044178B2 (en) *	2007-08-30	2015-06-02	Pepex Biomedical, Llc	Electrochemical sensor and method for manufacturing
US8951377B2 (en)	2008-11-14	2015-02-10	Pepex Biomedical, Inc.	Manufacturing electrochemical sensor module
US8506740B2 (en)	2008-11-14	2013-08-13	Pepex Biomedical, Llc	Manufacturing electrochemical sensor module
US9445755B2 (en)	2008-11-14	2016-09-20	Pepex Biomedical, Llc	Electrochemical sensor module
US9351677B2 (en)	2009-07-02	2016-05-31	Dexcom, Inc.	Analyte sensor with increased reference capacity
US20110024043A1 (en) *	2009-07-02	2011-02-03	Dexcom, Inc.	Continuous analyte sensors and methods of making same
WO2012159040A2 (en)	2011-05-19	2012-11-22	Pepex Biomedical Inc.	Fluid management and patient monitoring system
WO2012162151A2 (en)	2011-05-20	2012-11-29	Pepex Biomedical, Inc.	Manufacturing electrochemical sensor modules
CN104918551B (zh)	2012-12-03	2019-07-26	Pepex生物医药有限公司	传感器模块以及使用传感器模块的方法
EP2769689B8 (en)	2013-02-25	2018-06-27	Stryker European Holdings I, LLC	Computer-implemented technique for calculating a position of a surgical device
CN107003264B (zh)	2014-06-04	2020-02-21	普佩克斯生物医药有限公司	电化学传感器和使用先进印刷技术制造电化学传感器的方法
CN104865301B (zh) *	2015-04-27	2017-10-03	清华大学	一种共轴型复合式氧微电极及其制备方法
CN108607796A (zh) *	2016-12-21	2018-10-02	中国航空制造技术研究院	一种电解加工阴极绝缘涂层的制备方法
CN111505071B (zh) *	2020-04-13	2022-06-10	商丘师范学院	一种pH和AA同时检测一体化微电极传感器及其制备方法和应用
FR3118177B1 (fr) *	2020-12-22	2024-10-04	Commissariat Energie Atomique	Électrode pour biocapteur enzymatique à matériau fibreux, son procédé de préparation et ledit biocapteur

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3129161A (en) *	1958-10-10	1964-04-14	Engelhard Ind Inc	Reference electrode assembly
CH559912A5 (ja) *	1971-09-09	1975-03-14	Hoffmann La Roche
US4108757A (en) *	1974-08-07	1978-08-22	308489 Ontario Limited	Carbon fiber electrode
US4016063A (en) *	1975-08-06	1977-04-05	Desmond Arpad Radnoti	Electrode shield
US4119513A (en) *	1977-03-07	1978-10-10	Uop Inc.	Oxygen sensor for industrial air/fuel control
US4369104A (en) *	1979-10-22	1983-01-18	Hitco	Continuous filament graphite composite electrodes
DE3129988A1 (de) *	1981-07-29	1983-02-17	Siemens AG, 1000 Berlin und 8000 München	"verfahren und vorrichtung zur bestimmung von harnstoff"
US4680100A (en) *	1982-03-16	1987-07-14	American Cyanamid Company	Electrochemical cells and electrodes therefor
US4439303A (en) *	1982-06-28	1984-03-27	Maurice Cocchi	Crystallographically-oriented spatially-dispersed conductive fiber electrode
US4431508A (en) *	1982-12-10	1984-02-14	Brown Jr Harold M	Solid state graphite electrode
US4473450A (en) *	1983-04-15	1984-09-25	Raychem Corporation	Electrochemical method and apparatus
JPS6052759A (ja) *	1983-08-31	1985-03-26	Terumo Corp	酸素センサ−
JPS6077984A (ja) *	1983-10-05	1985-05-02	Rikagaku Kenkyusho	イオン注入による炭素電極
JPS617463A (ja) *	1984-06-22	1986-01-14	Sadaichi Murai	カーボン電極を備えたｐＨおよびイオン濃度測定用電極の製造方法
US4561963A (en) *	1984-07-30	1985-12-31	Zinetics Medical Technology Corporation	Antimony and graphite hydrogen ion electrode and method of making such electrode
GB8508053D0 (en) *	1985-03-28	1985-05-01	Genetics Int Inc	Graphite electrode

1987
- 1987-04-21 EP EP87902741A patent/EP0266432B1/en not_active Expired - Lifetime
- 1987-04-21 WO PCT/JP1987/000252 patent/WO1987006701A1/ja not_active Ceased
- 1987-04-21 US US07/143,154 patent/US4908115A/en not_active Expired - Fee Related
- 1987-04-21 DE DE8787902741T patent/DE3776081D1/de not_active Expired - Fee Related
- 1987-12-21 DK DK673187A patent/DK167716B1/da not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK673187D0 (da)	1987-12-21
DK673187A (da)	1987-12-22
DE3776081D1 (de)	1992-02-27
EP0266432B1 (en)	1992-01-15
US4908115A (en)	1990-03-13
EP0266432A1 (en)	1988-05-11
EP0266432A4 (en)	1988-09-28
WO1987006701A1 (fr)	1987-11-05

Publication	Publication Date	Title
DK167716B1 (da)	1993-12-06	Mikroelektrode til elektrokemisk analyse
US6413396B1 (en)	2002-07-02	Enzyme electrode sensor and manufacturing method thereof
KR890004367B1 (ko)	1989-10-31	효소센서
Zhang et al.	1999	Glucose nanosensor based on Prussian‐blue modified carbon‐fiber cone nanoelectrode and an integrated reference electrode
Wang et al.	1994	Enzyme microelectrode array strips for glucose and lactate
Roy et al.	2006	Vertically aligned carbon nanotube probes for monitoring blood cholesterol
Miao et al.	1999	Construction of a glucose biosensor immobilized with glucose oxidase in the film of polypyrrole nanotubules
Jobst et al.	1993	Thin-film Clark-type oxygen sensor based on novel polymer membrane systems for in vivo and biosensor applications
JPH09229894A (ja)	1997-09-05	選択性が向上し、感度が強化された電気化学的センサー
JPH10505421A (ja)	1998-05-26	皮下グルコース電極
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Wang et al.	1994	Ultrathin porous carbon films as amperometric transducers for biocatalytic sensors
Liu et al.	2018	Enzyme biosensors for point-of-care testing
Wang et al.	2000	One-step electropolymeric co-immobilization of glucose oxidase and heparin for amperometric biosensing of glucose
Yu et al.	2005	Coil-type implantable glucose biosensor with excess enzyme loading
Mac Kenna et al.	2015	Impedimetric transduction of swelling in pH-responsive hydrogels
Navera et al.	1993	Nafion‐coated carbon fiber for acetylcholine and choline sensors
CN108333241A (zh)	2018-07-27	电化学生物传感器用修饰电极及其制备方法、电化学生物传感器及其制备方法和应用
Yang et al.	1998	An Integrated Needle‐Type Biosensor for Intravascular Glucose and Lactate Monitoring
Netchiporouk et al.	1995	Properties of carbon fibre microelectrodes as a basis for enzyme biosensors
KR101163678B1 (ko)	2012-07-09	크레아틴의 방해영향을 줄인 크레아티닌 바이오센서
Navera et al.	1993	Micro-choline sensor for acetylcholinesterase determination
Wang et al.	2023	An all-solid-state potentiometric microsensor for real-time monitoring of the calcification process by Bacillus subtilis biofilms
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JPH0358663B2 (ja)	1991-09-06

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Date	Code	Title	Description
1993-12-06	B1	Patent granted (law 1993)
1995-12-27	PBP	Patent lapsed