DK1670778T3 - Omlejrede pentanoler, en fremgangsmåde til fremstilling heraf og anvendelse heraf som betændelsehæmmende - Google Patents

Omlejrede pentanoler, en fremgangsmåde til fremstilling heraf og anvendelse heraf som betændelsehæmmende

Info

Publication number: DK1670778T3
Authority: DK; Denmark
Prior art keywords: inflammatory; pentanols; rearranged; preparation; compounds
Prior art date: 2003-10-08

Application number

DK04790276T

Other languages

Danish (da)

English (en)

Inventor

Stefan Baeurle

Markus Berger

Heike Schaecke

Duy Nguyen

Werner Skuballa

Anne Mengel

Stefan Jaroch

Hartmut Rehwinkel

Norbert Schmees

Konrad Krolikiewicz

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-10-08

Filing date

2004-10-06

Publication date

2007-03-26

2004-10-06 Application filed by Schering Ag filed Critical Schering Ag

2007-03-26 Application granted granted Critical

2007-03-26 Publication of DK1670778T3 publication Critical patent/DK1670778T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/74—Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/76—Benzo[c]pyrans

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Hematology (AREA)
Diabetes (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Otolaryngology (AREA)
Oncology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Ophthalmology & Optometry (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Biomedical Technology (AREA)
Transplantation (AREA)
Vascular Medicine (AREA)
Surgery (AREA)
Gastroenterology & Hepatology (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK04790276T 2003-10-08 2004-10-06 Omlejrede pentanoler, en fremgangsmåde til fremstilling heraf og anvendelse heraf som betændelsehæmmende DK1670778T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10347385A DE10347385A1 (de)	2003-10-08	2003-10-08	Umgelagerte Pentanole, ein Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer
PCT/EP2004/011375 WO2005035518A1 (de)	2003-10-08	2004-10-06	Umgelagerte pentanole, ein verfahren zu ihrer herstellung und ihre verwendung als entzündungshemmer

Publications (1)

Publication Number	Publication Date
DK1670778T3 true DK1670778T3 (da)	2007-03-26

Family

ID=34428339

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK04790276T DK1670778T3 (da)	2003-10-08	2004-10-06	Omlejrede pentanoler, en fremgangsmåde til fremstilling heraf og anvendelse heraf som betændelsehæmmende

Country Status (24)

Country	Link
US (1)	US7442794B2 (pl)
EP (1)	EP1670778B1 (pl)
JP (1)	JP2007508269A (pl)
KR (1)	KR20060120659A (pl)
CN (1)	CN1867555A (pl)
AT (1)	ATE345334T1 (pl)
AU (1)	AU2004279583A1 (pl)
BR (1)	BRPI0415203A (pl)
CA (1)	CA2539878A1 (pl)
CR (1)	CR8358A (pl)
CY (1)	CY1105994T1 (pl)
DE (2)	DE10347385A1 (pl)
DK (1)	DK1670778T3 (pl)
EA (1)	EA009958B1 (pl)
EC (1)	ECSP066540A (pl)
ES (1)	ES2277296T3 (pl)
IL (1)	IL174469A0 (pl)
MX (1)	MXPA06003999A (pl)
NO (1)	NO20062021L (pl)
PL (1)	PL1670778T3 (pl)
PT (1)	PT1670778E (pl)
RS (1)	RS20060297A (pl)
WO (1)	WO2005035518A1 (pl)
ZA (1)	ZA200603602B (pl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10347385A1 (de)	2003-10-08	2005-05-12	Schering Ag	Umgelagerte Pentanole, ein Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer
US20060012020A1 (en) *	2004-07-14	2006-01-19	Gilleo Kenneth B	Wafer-level assembly method for semiconductor devices
AU2007242851A1 (en)	2006-04-20	2007-11-01	Glaxo Group Limited	Novel compounds
EP1878717A1 (en) *	2006-07-14	2008-01-16	Bayer Schering Pharma Aktiengesellschaft	Benzyl amines, a process for their production and their use as anti-inflammatory agents
EP2062880A1 (en)	2007-11-22	2009-05-27	Bayer Schering Pharma Aktiengesellschaft	5-[(3,3,3-Trifluoro-2-hydroxy-1-arylpropyl)amino]-1H-quinolin-2-ones, a process for their production and their use as anti-inflammatory agents
EP2149558A1 (en) *	2008-07-21	2010-02-03	Bayer Schering Pharma Aktiengesellschaft	5-[(3,3,3-Trifluoro-2-hydroxy-1-arylpropyl)amino-1-arylquinolin-2-ones, a process for their production and their use as anti-inflammatory agents
US20100016338A1 (en) *	2008-07-21	2010-01-21	Bayer Schering Pharma Aktiengesellschaft	5-[(3,3,3-Trifluoro-2-hydroxy-1-arylpropyl)amino]-1-arylquinolin-2-ones, a Process for their Production and their Use as Anti-inflammatory Agents
US8236786B2 (en)	2008-08-07	2012-08-07	Pulmagen Therapeutics (Inflammation) Limited	Respiratory disease treatment
WO2010076553A1 (en)	2008-12-30	2010-07-08	Dr. Reddy's Laboratories Ltd	Sulfonamide compounds for the treatment of respiratory disorders
WO2010150014A1 (en)	2009-06-24	2010-12-29	Pulmagen Therapeutics (Inflammation) Limited	5r- 5 -deuterated glitazones for respiratory disease treatment
WO2011098746A1 (en)	2010-02-09	2011-08-18	Pulmagen Therapeutics (Inflammation) Limited	Crystalline acid addition salts of ( 5r) -enanti0mer of pioglitazone
GB201002243D0 (en)	2010-02-10	2010-03-31	Argenta Therapeutics Ltd	Respiratory disease treatment
GB201002224D0 (en)	2010-02-10	2010-03-31	Argenta Therapeutics Ltd	Respiratory disease treatment
JP6250561B2 (ja)	2012-02-08	2017-12-20	サノビオンファーマシューティカルズインクＳｕｎｏｖｉｏｎＰｈａｒｍａｃｅｕｔｉｃａｌｓＩｎｃ．	ヘテロアリール化合物およびそれらの使用方法
JP7187437B2 (ja)	2016-07-29	2022-12-12	サノビオンファーマシューティカルズインク	化合物および組成物ならびにそれらの使用
EP3490607A4 (en)	2016-07-29	2020-04-08	Sunovion Pharmaceuticals Inc.	COMPOUNDS AND COMPOSITIONS, AND USES THEREOF
WO2018046678A1 (de) *	2016-09-08	2018-03-15	Bayer Aktiengesellschaft	Glukokorticoid-rezeptor-agonisten enthaltende formulierungen
WO2018046684A1 (en) *	2016-09-08	2018-03-15	Bayer Pharma Aktiengesellschaft	Process for the preparation of substituted 5-{[2-(alkoxymethyl)-3,3,3-trifluoro-2-hydroxy-1-phenylpropyl]amino}quinolin-2(1h)-ones
SG11202000669VA (en)	2017-08-02	2020-02-27	Sunovion Pharmaceuticals Inc	Isochroman compounds and uses thereof
KR20210139376A (ko)	2019-03-14	2021-11-22	선오비온 파마슈티컬스 인코포레이티드	이소크로마닐 화합물의 염, 및 이의 결정성 형태, 제조방법, 치료 용도 및 약제학적 조성물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19856475A1 (de) *	1998-11-27	2000-05-31	Schering Ag	Nichtsteroidale Entzündungshemmer
DE10038639A1 (de) *	2000-07-28	2002-02-21	Schering Ag	Nichtsteroidale Entzündungshemmer
EP1375517A1 (en) *	2002-06-21	2004-01-02	Smithkline Beecham Corporation	Structure of a glucocorticoid receptor ligand binding domain comprising an expanded binding pocket and methods employing same
DE10347385A1 (de)	2003-10-08	2005-05-12	Schering Ag	Umgelagerte Pentanole, ein Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer

2003
- 2003-10-08 DE DE10347385A patent/DE10347385A1/de not_active Ceased
2004
- 2004-10-06 KR KR1020067006695A patent/KR20060120659A/ko not_active Withdrawn
- 2004-10-06 ES ES04790276T patent/ES2277296T3/es not_active Expired - Lifetime
- 2004-10-06 RS YUP-2006/0297A patent/RS20060297A/sr unknown
- 2004-10-06 BR BRPI0415203-4A patent/BRPI0415203A/pt not_active IP Right Cessation
- 2004-10-06 MX MXPA06003999A patent/MXPA06003999A/es not_active Application Discontinuation
- 2004-10-06 PL PL04790276T patent/PL1670778T3/pl unknown
- 2004-10-06 WO PCT/EP2004/011375 patent/WO2005035518A1/de not_active Ceased
- 2004-10-06 AU AU2004279583A patent/AU2004279583A1/en not_active Abandoned
- 2004-10-06 DK DK04790276T patent/DK1670778T3/da active
- 2004-10-06 AT AT04790276T patent/ATE345334T1/de not_active IP Right Cessation
- 2004-10-06 JP JP2006530143A patent/JP2007508269A/ja not_active Withdrawn
- 2004-10-06 DE DE502004002037T patent/DE502004002037D1/de not_active Expired - Fee Related
- 2004-10-06 PT PT04790276T patent/PT1670778E/pt unknown
- 2004-10-06 CA CA002539878A patent/CA2539878A1/en not_active Abandoned
- 2004-10-06 EP EP04790276A patent/EP1670778B1/de not_active Expired - Lifetime
- 2004-10-06 CN CNA2004800296382A patent/CN1867555A/zh active Pending
- 2004-10-06 EA EA200600605A patent/EA009958B1/ru not_active IP Right Cessation
- 2004-10-08 US US10/960,757 patent/US7442794B2/en not_active Expired - Fee Related
2006
- 2006-03-21 IL IL174469A patent/IL174469A0/en unknown
- 2006-04-24 CR CR8358A patent/CR8358A/es not_active Application Discontinuation
- 2006-05-02 EC EC2006006540A patent/ECSP066540A/es unknown
- 2006-05-05 NO NO20062021A patent/NO20062021L/no not_active Application Discontinuation
- 2006-05-05 ZA ZA200603602A patent/ZA200603602B/en unknown
2007
- 2007-02-08 CY CY20071100165T patent/CY1105994T1/el unknown

Also Published As

Publication number	Publication date
US7442794B2 (en)	2008-10-28
CR8358A (es)	2006-10-06
NO20062021L (no)	2006-07-07
EA200600605A1 (ru)	2006-10-27
BRPI0415203A (pt)	2006-12-05
PT1670778E (pt)	2007-02-28
CA2539878A1 (en)	2005-04-21
IL174469A0 (en)	2006-08-01
ECSP066540A (es)	2006-10-17
CY1105994T1 (el)	2011-04-06
ES2277296T3 (es)	2007-07-01
DE10347385A1 (de)	2005-05-12
CN1867555A (zh)	2006-11-22
ZA200603602B (en)	2007-07-25
JP2007508269A (ja)	2007-04-05
WO2005035518A1 (de)	2005-04-21
ATE345334T1 (de)	2006-12-15
EP1670778A1 (de)	2006-06-21
DE502004002037D1 (de)	2006-12-28
RS20060297A (sr)	2008-08-07
US20050131226A1 (en)	2005-06-16
AU2004279583A1 (en)	2005-04-21
MXPA06003999A (es)	2006-07-05
EP1670778B1 (de)	2006-11-15
KR20060120659A (ko)	2006-11-27
PL1670778T3 (pl)	2007-04-30
EA009958B1 (ru)	2008-04-28

Publication	Publication Date	Title
DK1670778T3 (da)	2007-03-26	Omlejrede pentanoler, en fremgangsmåde til fremstilling heraf og anvendelse heraf som betændelsehæmmende
NO20064032L (no)	2006-11-08	DPP-IV inhibitorer
EA200500203A1 (ru)	2005-08-25	Новый способ синтеза и новая кристаллическая форма агомелатина и фармацевтические композиции, которые её содержат
WO2007015017A3 (fr)	2007-05-10	Nouveaux derives de polyquinoleines et leur utilisation therapeutique
NO20065946L (no)	2006-12-20	DPP-IV-inhibitorer
SE0401762D0 (sv)	2004-07-05	Novel compounds
DK1456212T3 (da)	2007-04-02	6-aminomorphinanderivater, fremgangsmåder til fremstilling heraf og disses anvendelse
NO20071254L (no)	2007-03-22	Fremgangsmate for fremstilling av irbesartan og mellomprodukter derav.
DE50202504D1 (de)	2005-04-21	Neue 4-aminofuropyrimidine und ihre verwendung
UA97806C2 (ru)	2012-03-26	Бензиламины, способ их получения и их применения в качестве противовоспалительных средств
NO20084301L (no)	2008-12-12	Tetrahydronaftalenderivater, fremgangsmate for deres fremstilling og anvendelse derav som anti-inflammatoriske midler
ATE441630T1 (de)	2009-09-15	Substituierte cyclopenten-verbindungen
NO20064344L (no)	2006-10-19	Caspaseinhibitorer og anvendelser derav
SE0403086D0 (sv)	2004-12-17	Compounds
NO20080839L (no)	2008-02-18	Isotopsubstituerte protonpumpeinhibitorer
DK1831239T3 (da)	2010-06-28	Fremgangsmåde til fremstilling af 17-hydroxy-6 beta, 7 beta, 15 beta, 16 beta-bismethylen-17alpha-pregn-4-en-3-on-21-carboxylsyre-lambda-lacton og nøgle-mellemprodukter til denne fremgangsmåde
EA200700550A1 (ru)	2007-10-26	Производные алкилидентетрагидронафталина, способ их получения и их применение в качестве противовоспалительных средств
NO20083352L (no)	2008-07-30	2-karbamid-4-fenyltiazolderivater, fremstilling og terapeutisk anvendelse derav
ATE471312T1 (de)	2010-07-15	Diaryltriazolmethylamin-derivate sowie ihre herstellung und therapeutische verwendung
DK1638948T3 (da)	2009-02-02	Diphenylurinstofderivater og deres anvendelse som chloridkanalblokkere
TW200519071A (en)	2005-06-16	3-aryl-2-cyano-3-hydroxy-acrylic acid derivatives
EA200702590A1 (ru)	2008-06-30	Ингибиторы растворимой аденилатциклазы
ATE417055T1 (de)	2008-12-15	Steroid modifizierte solatriosen
NO20064410L (no)	2006-09-29	Fremgangsmate for fremstilling av tryptaseinhibitorer
CY1106649T1 (el)	2012-01-25	Νεα 1-μεθοξυ-2-φαινυλ-αιθενια χρησιμα δια την παρασκευην 5-καρβοξαλδεϋδο-2,3-διϋδροβενζοξεπινων