DK1525188T3 - Hidtil ukendte derivater af 4,4-dithiobis-(3-aminobutan-1-sulfonater) og sammensætninger, der indeholder dem - Google Patents
Hidtil ukendte derivater af 4,4-dithiobis-(3-aminobutan-1-sulfonater) og sammensætninger, der indeholder demInfo
- Publication number
- DK1525188T3 DK1525188T3 DK03753648T DK03753648T DK1525188T3 DK 1525188 T3 DK1525188 T3 DK 1525188T3 DK 03753648 T DK03753648 T DK 03753648T DK 03753648 T DK03753648 T DK 03753648T DK 1525188 T3 DK1525188 T3 DK 1525188T3
- Authority
- DK
- Denmark
- Prior art keywords
- aminobutane
- dithiobis
- sulfonates
- compositions containing
- novel derivatives
- Prior art date
Links
- HZHMBNYJWQUCHI-UHFFFAOYSA-N 3-aminobutane-1-sulfonic acid Chemical class CC(N)CCS(O)(=O)=O HZHMBNYJWQUCHI-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 206010020772 Hypertension Diseases 0.000 abstract 1
- JXLHNMVSKXFWAO-UHFFFAOYSA-N azane;7-fluoro-2,1,3-benzoxadiazole-4-sulfonic acid Chemical compound N.OS(=O)(=O)C1=CC=C(F)C2=NON=C12 JXLHNMVSKXFWAO-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000001971 neopentyl group Chemical group [H]C([*])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
- C07C323/66—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfo, esterified sulfo or halosulfonyl groups, bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0208977A FR2842522B1 (fr) | 2002-07-16 | 2002-07-16 | Derives de 4,4'-dithiobis-(3-aminobutane-1-sulfonates) nouveaux et compositons les contenant |
| FR0303425A FR2852597A1 (fr) | 2003-03-20 | 2003-03-20 | Derives de 4,4'-dithiobis-(3-aminobutane-1-sulfonates) nouveaux et compositions les contenant |
| PCT/FR2003/002242 WO2004007441A2 (fr) | 2002-07-16 | 2003-07-16 | Derives de 4,4' -dithiobis- (3-aminobutane-1-sulfonates) nouveaux et compositions les contenant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1525188T3 true DK1525188T3 (da) | 2008-11-17 |
Family
ID=30117028
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03753648T DK1525188T3 (da) | 2002-07-16 | 2003-07-16 | Hidtil ukendte derivater af 4,4-dithiobis-(3-aminobutan-1-sulfonater) og sammensætninger, der indeholder dem |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7235687B2 (da) |
| EP (1) | EP1525188B1 (da) |
| AT (1) | ATE400552T1 (da) |
| AU (1) | AU2003271811A1 (da) |
| CY (1) | CY1109013T1 (da) |
| DE (1) | DE60322064D1 (da) |
| DK (1) | DK1525188T3 (da) |
| ES (1) | ES2309336T3 (da) |
| PT (1) | PT1525188E (da) |
| SI (1) | SI1525188T1 (da) |
| WO (1) | WO2004007441A2 (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2533767T3 (es) | 2005-04-15 | 2015-04-15 | Epigenomics Ag | Métodos para el análisis de trastornos proliferativos celulares |
| FR2931151A1 (fr) * | 2008-05-13 | 2009-11-20 | Pharmaleads Soc Par Actions Si | Nouveaux derives d'amino-acides, leur procede de preparation et leur utilisation therapeutique |
| EP2322514A1 (en) * | 2009-11-11 | 2011-05-18 | Bayer Schering Pharma Aktiengesellschaft | Homoglutamic acid and glutamic acid derivatives |
| EP2439192A1 (en) * | 2010-10-07 | 2012-04-11 | Quantum Genomics | Method for the preparation of (3S,3S') 4,4'-disulfanediylbis (3-aminobutane 1-sulfonic acid) |
| JP6212500B2 (ja) | 2011-12-21 | 2017-10-11 | クァンタム ジェノミックＱｕａｎｔｕｍ Ｇｅｎｏｍｉｃｓ | （３ｓ，３ｓ’）４，４’−ジスルファンジイルビス（３−アミノブタン１−スルホン酸）および第２の抗高血圧剤の組合せ |
| EP2722327A1 (en) | 2012-10-22 | 2014-04-23 | Quantum Genomics | Crystalline phase of (3S,3S') 4,4'-disulfanediylbis (3-aminobutane 1-sulfonic acid) with L-lysine |
| CA2964474A1 (en) * | 2014-10-17 | 2016-04-21 | University Of Florida Research Foundation | Novel small molecule anticancer agents |
| US10501426B1 (en) | 2019-01-11 | 2019-12-10 | King Saud University | Synthesis of thiazole derivative as anticancer and anti-antibiotics resistant bacteria agent |
| CN110845347B (zh) * | 2019-11-21 | 2021-10-15 | 利尔化学股份有限公司 | 一种氯代高丝氨酸烷基酯的制备方法 |
| TW202207917A (zh) | 2020-05-06 | 2022-03-01 | 法商量子基因科技有限公司 | 包含腦胺肽酶抑制劑、利尿劑及全身性腎素－血管收縮素系統阻斷劑之醫藥組合物 |
| WO2022225712A1 (en) | 2021-04-22 | 2022-10-27 | Teva Pharmaceuticals International Gmbh | Solid state forms of firibastat and processes for preparation thereof |
| CN115448833B (zh) * | 2022-08-25 | 2024-07-05 | 湖北泰盛化工有限公司 | 一种多官能团脂肪族伯醇衍生物的羟基直接氯代方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2773712B1 (fr) * | 1998-01-16 | 2000-06-02 | Inst Nat Sante Rech Med | Composition pharmaceutique comprenant au moins un inhibiteur de l'aminopeptidase a |
-
2003
- 2003-07-16 DK DK03753648T patent/DK1525188T3/da active
- 2003-07-16 PT PT03753648T patent/PT1525188E/pt unknown
- 2003-07-16 WO PCT/FR2003/002242 patent/WO2004007441A2/fr not_active Ceased
- 2003-07-16 US US10/521,171 patent/US7235687B2/en not_active Expired - Lifetime
- 2003-07-16 SI SI200331379T patent/SI1525188T1/sl unknown
- 2003-07-16 EP EP03753648A patent/EP1525188B1/fr not_active Expired - Lifetime
- 2003-07-16 ES ES03753648T patent/ES2309336T3/es not_active Expired - Lifetime
- 2003-07-16 AT AT03753648T patent/ATE400552T1/de active
- 2003-07-16 AU AU2003271811A patent/AU2003271811A1/en not_active Abandoned
- 2003-07-16 DE DE60322064T patent/DE60322064D1/de not_active Expired - Lifetime
-
2008
- 2008-10-07 CY CY20081101109T patent/CY1109013T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003271811A1 (en) | 2004-02-02 |
| WO2004007441A2 (fr) | 2004-01-22 |
| US7235687B2 (en) | 2007-06-26 |
| CY1109013T1 (el) | 2014-07-02 |
| PT1525188E (pt) | 2008-10-16 |
| SI1525188T1 (sl) | 2008-12-31 |
| DE60322064D1 (de) | 2008-08-21 |
| EP1525188B1 (fr) | 2008-07-09 |
| EP1525188A2 (fr) | 2005-04-27 |
| AU2003271811A8 (en) | 2004-02-02 |
| US20060135602A1 (en) | 2006-06-22 |
| ATE400552T1 (de) | 2008-07-15 |
| ES2309336T3 (es) | 2008-12-16 |
| WO2004007441A3 (fr) | 2004-04-08 |
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