DK1523548T3 - Polynukleotidsekvenser, som koder for alkaliske alfa-galactosidaser, og fremgangsmåder til anvendelse heraf - Google Patents

Polynukleotidsekvenser, som koder for alkaliske alfa-galactosidaser, og fremgangsmåder til anvendelse heraf

Info

Publication number: DK1523548T3
Authority: DK; Denmark
Prior art keywords: polynucleotide sequences; galactosidases; methods; sequences encoding; alpha
Prior art date: 2002-05-15

Application number

DK03723021.6T

Other languages

English (en)

Inventor

Arthur Schaffer

Nir Carmi

Marina Petreikov

David Granot

Yoram Eyal

Original Assignee

Agricultural Res Org

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-05-15

Filing date

2003-05-15

Publication date

2010-05-10

2003-05-15 Application filed by Agricultural Res Org filed Critical Agricultural Res Org

2010-05-10 Application granted granted Critical

2010-05-10 Publication of DK1523548T3 publication Critical patent/DK1523548T3/da

Links

108091033319 polynucleotide Proteins 0.000 title abstract 3
102000040430 polynucleotide Human genes 0.000 title abstract 3
239000002157 polynucleotide Substances 0.000 title abstract 3
102000005840 alpha-Galactosidase Human genes 0.000 title 1
108010030291 alpha-Galactosidase Proteins 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 3
108091034117 Oligonucleotide Proteins 0.000 abstract 2
102000004196 processed proteins & peptides Human genes 0.000 abstract 2
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
229920001184 polypeptide Polymers 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2465—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on alpha-galactose-glycoside bonds, e.g. alpha-galactosidase (3.2.1.22)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
Biomedical Technology (AREA)
General Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Enzymes And Modification Thereof (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

DK03723021.6T 2002-05-15 2003-05-15 Polynukleotidsekvenser, som koder for alkaliske alfa-galactosidaser, og fremgangsmåder til anvendelse heraf DK1523548T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US38025402P	2002-05-15	2002-05-15
PCT/IL2003/000392 WO2003097791A2 (en)	2002-05-15	2003-05-15	Polynucleotide sequences encoding alkaline a-galactosidases and methods of using same

Publications (1)

Publication Number	Publication Date
DK1523548T3 true DK1523548T3 (da)	2010-05-10

Family

ID=29549942

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK03723021.6T DK1523548T3 (da)	2002-05-15	2003-05-15	Polynukleotidsekvenser, som koder for alkaliske alfa-galactosidaser, og fremgangsmåder til anvendelse heraf

Country Status (7)

Country	Link
US (1)	US7560262B2 (da)
EP (1)	EP1523548B1 (da)
AT (1)	ATE453705T1 (da)
AU (1)	AU2003235988A1 (da)
DE (1)	DE60330779D1 (da)
DK (1)	DK1523548T3 (da)
WO (1)	WO2003097791A2 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2003235988A1 (en)	2002-05-15	2003-12-02	Agricultural Research Organization, The Volcani Center	Polynucleotide sequences encoding alkaline a-galactosidases and methods of using same
EP1593685B1 (en) *	2004-05-04	2008-07-09	Kraft Foods Holdings, Inc.	Peptide antioxidants from soy protein
BRPI0815324A2 (pt)	2007-08-20	2015-07-14	Protalix Ltd	"conjugado protêico que contém sacarídeos, processo de separação do conjugado protêico que contém sacarídeos, composição farmacêutica do conjugado protêico que contém sacarídeos, uso do conjugado protêico que contém sacarídeos e composto do conjugado protêico que contém sacarídeos"
US20120230974A1 (en)	2009-11-17	2012-09-13	Protalix Ltd	Alkaline alpha galactosidase for the treatment of fabry disease
US9194011B2 (en)	2009-11-17	2015-11-24	Protalix Ltd.	Stabilized alpha-galactosidase and uses thereof
BR112012022029B1 (pt)	2010-03-02	2022-10-11	Protalix Ltd	Estrutura de proteina multimérica, seu uso e processo para preparação da estrutura de proteína multimérica
ES2774190T3 (es)	2011-01-20	2020-07-17	Protalix Ltd	Composiciones de alfa-galactosidasa
WO2017202966A1 (en) *	2016-05-24	2017-11-30	Novozymes A/S	Polypeptides having alpha-galactosidase activity and polynucleotides encoding same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL125423A (en) *	1998-07-20	2004-08-31	Israel State	Alkaline alpha-galactosidase having broad substrate specificity
AU2003235988A1 (en)	2002-05-15	2003-12-02	Agricultural Research Organization, The Volcani Center	Polynucleotide sequences encoding alkaline a-galactosidases and methods of using same

2003
- 2003-05-15 AU AU2003235988A patent/AU2003235988A1/en not_active Abandoned
- 2003-05-15 DE DE60330779T patent/DE60330779D1/de not_active Expired - Lifetime
- 2003-05-15 EP EP03723021A patent/EP1523548B1/en not_active Expired - Lifetime
- 2003-05-15 DK DK03723021.6T patent/DK1523548T3/da active
- 2003-05-15 AT AT03723021T patent/ATE453705T1/de not_active IP Right Cessation
- 2003-05-15 WO PCT/IL2003/000392 patent/WO2003097791A2/en not_active Ceased
2004
- 2004-11-15 US US10/990,156 patent/US7560262B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US20050208520A1 (en)	2005-09-22
WO2003097791A2 (en)	2003-11-27
US7560262B2 (en)	2009-07-14
EP1523548A4 (en)	2006-03-08
WO2003097791A3 (en)	2005-02-24
EP1523548B1 (en)	2009-12-30
EP1523548A2 (en)	2005-04-20
DE60330779D1 (de)	2010-02-11
ATE453705T1 (de)	2010-01-15
AU2003235988A8 (en)	2003-12-02
AU2003235988A1 (en)	2003-12-02

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