DK1597282T3 - Antistofmolekyler, der har specificitet for human IL-1 beta - Google Patents
Antistofmolekyler, der har specificitet for human IL-1 betaInfo
- Publication number
- DK1597282T3 DK1597282T3 DK04708808.3T DK04708808T DK1597282T3 DK 1597282 T3 DK1597282 T3 DK 1597282T3 DK 04708808 T DK04708808 T DK 04708808T DK 1597282 T3 DK1597282 T3 DK 1597282T3
- Authority
- DK
- Denmark
- Prior art keywords
- specificity
- beta
- human
- antibody molecules
- antibody
- Prior art date
Links
- 101001033249 Homo sapiens Interleukin-1 beta Proteins 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/245—IL-1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Transplantation (AREA)
- Plant Pathology (AREA)
- Communicable Diseases (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Physics & Mathematics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0303337.0A GB0303337D0 (en) | 2003-02-13 | 2003-02-13 | Biological products |
| PCT/GB2004/000463 WO2004072116A2 (en) | 2003-02-13 | 2004-02-06 | ANTIBODY MOLECULES HAVING SPECIFICITY FOR HUMAN IL-1β |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1597282T3 true DK1597282T3 (da) | 2012-01-23 |
Family
ID=9952969
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04708808.3T DK1597282T3 (da) | 2003-02-13 | 2004-02-06 | Antistofmolekyler, der har specificitet for human IL-1 beta |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US7608694B2 (da) |
| EP (2) | EP1597282B1 (da) |
| JP (2) | JP4668896B2 (da) |
| KR (1) | KR20050099509A (da) |
| CN (1) | CN1745103A (da) |
| AR (1) | AR043159A1 (da) |
| AT (1) | ATE525397T1 (da) |
| AU (1) | AU2004210776B2 (da) |
| BR (1) | BRPI0407233A (da) |
| CA (1) | CA2515474C (da) |
| CL (1) | CL2004000259A1 (da) |
| CY (1) | CY1112507T1 (da) |
| DK (1) | DK1597282T3 (da) |
| EA (1) | EA200501286A1 (da) |
| EC (1) | ECSP056014A (da) |
| ES (1) | ES2373953T3 (da) |
| GB (1) | GB0303337D0 (da) |
| IS (1) | IS8013A (da) |
| MX (1) | MXPA05007392A (da) |
| NO (1) | NO20054223L (da) |
| PE (1) | PE20040947A1 (da) |
| PL (1) | PL378412A1 (da) |
| PT (1) | PT1597282E (da) |
| SI (1) | SI1597282T1 (da) |
| TW (1) | TW200505942A (da) |
| WO (1) | WO2004072116A2 (da) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0303337D0 (en) | 2003-02-13 | 2003-03-19 | Celltech R&D Ltd | Biological products |
| JP5102028B2 (ja) | 2004-07-26 | 2012-12-19 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 抗cd154抗体 |
| EP1851245B1 (en) | 2005-01-26 | 2012-10-10 | Amgen Fremont Inc. | Antibodies against interleukin-1 beta |
| PT1899378E (pt) | 2005-06-21 | 2010-01-26 | Xoma Technology Ltd | Anticorpos de ligação de il-1β e os seus fragmentos |
| GB0513852D0 (en) * | 2005-07-06 | 2005-08-10 | Celltech R&D Ltd | Biological products |
| PL1940465T3 (pl) * | 2005-10-26 | 2013-01-31 | Novartis Ag | Nowe zastosowanie przeciwciał anty-IL-1beta |
| NZ569234A (en) | 2005-12-09 | 2011-07-29 | Ucb Pharma Sa | Antibody molecules having specificity for human IL-6 |
| GB0612928D0 (en) * | 2006-06-29 | 2006-08-09 | Ucb Sa | Biological products |
| GB0620729D0 (en) | 2006-10-18 | 2006-11-29 | Ucb Sa | Biological products |
| US7695718B2 (en) | 2006-12-20 | 2010-04-13 | Xoma Technology Ltd. | Methods for the treatment of IL-1β related diseases |
| EP2125894B1 (en) | 2007-03-22 | 2018-12-19 | Biogen MA Inc. | Binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind cd154 and uses thereof |
| GB0717337D0 (en) | 2007-09-06 | 2007-10-17 | Ucb Pharma Sa | Method of treatment |
| ES2660036T3 (es) | 2007-12-07 | 2018-03-20 | Zymogenetics, Inc. | Moléculas de anticuerpo humanizadas específicas para IL-31 |
| HRP20141194T1 (hr) | 2007-12-20 | 2015-04-24 | Xoma (Us) Llc | Postupci lijeäśenja gihta |
| GB0807413D0 (en) | 2008-04-23 | 2008-05-28 | Ucb Pharma Sa | Biological products |
| EA201001691A1 (ru) | 2008-04-28 | 2011-10-31 | Калобайос Фармасьютикалз, Инк. | Антитела к гранулоцитарно-макрофагальному колониестимулирующему фактору |
| WO2010028275A1 (en) | 2008-09-05 | 2010-03-11 | Xoma Technology Ltd. | METHODS FOR TREATING OR PREVENTING IL-1ß RELATED DISEASES |
| BRPI1008692B8 (pt) * | 2009-02-17 | 2021-05-25 | Ucb Biopharma Sprl | anticorpo antagonista tendo especificidade para ox40 humano, sequência de dna isolado, vetor de clonagem ou de expressão, célula hospedeira, processo para a produção do referido anticorpo, composição farmacêutica, uso do 5 referido anticorpo e proteína de fusão |
| GB0904214D0 (en) | 2009-03-11 | 2009-04-22 | Ucb Pharma Sa | Biological products |
| SI2993231T1 (sl) | 2009-09-24 | 2018-10-30 | Ucb Biopharma Sprl | Bakterijski sev za izražanje rekombinantnega proteina, ki ima proteazno deficientno DEGP-zadrževalno šaperonsko aktivnost, ter onesposobljena gena TSP in PTR |
| AR078650A1 (es) * | 2009-10-15 | 2011-11-23 | Abbott Lab | Anticuerpo de union a il-1 beta |
| GB201000590D0 (en) | 2010-01-14 | 2010-03-03 | Ucb Pharma Sa | Bacterial host strain |
| GB201000591D0 (en) | 2010-01-14 | 2010-03-03 | Ucb Pharma Sa | Bacterial hoist strain |
| GB201000587D0 (en) | 2010-01-14 | 2010-03-03 | Ucb Pharma Sa | Bacterial hoist strain |
| EA201201526A1 (ru) | 2010-05-07 | 2013-06-28 | Ксома Текнолоджи Лтд. | Способы лечения состояний, связанных с il-1b |
| PL2571532T3 (pl) * | 2010-05-14 | 2017-10-31 | Abbvie Inc | Białka wiążące IL-1 |
| GB201012599D0 (en) | 2010-07-27 | 2010-09-08 | Ucb Pharma Sa | Process for purifying proteins |
| US8465413B2 (en) | 2010-11-25 | 2013-06-18 | Coloplast A/S | Method of treating Peyronie's disease |
| ES2632583T3 (es) | 2011-01-14 | 2017-09-14 | Ucb Biopharma Sprl | Anticuerpo que se une a IL-17A e IL-17F |
| WO2013007388A1 (en) | 2011-07-13 | 2013-01-17 | Ucb Pharma, S.A. | Bacterial host strain expressing recombinant dsbc |
| UA112203C2 (uk) | 2011-11-11 | 2016-08-10 | Юсб Фарма С.А. | Злитий білок біоспецифічного антитіла, який зв'язується з ox40 людини та сироватковим альбуміном людини |
| EP2794657B1 (en) | 2011-12-19 | 2017-10-11 | Xoma (Us) Llc | Methods for treating acne |
| WO2013122544A2 (en) | 2012-02-13 | 2013-08-22 | Agency For Science, Technology And Research | IL-1β NEUTRALIZING HUMAN MONOCLONAL ANTIBODIES |
| WO2013157105A1 (ja) * | 2012-04-18 | 2013-10-24 | 公立大学法人大阪市立大学 | ムチンサブタイプ5ac特異的ヒト化抗体およびその利用 |
| WO2013157102A1 (ja) * | 2012-04-18 | 2013-10-24 | 公立大学法人大阪市立大学 | ムチンサブタイプ5ac特異的ヒト化抗体およびその利用 |
| GB201208367D0 (en) | 2012-05-14 | 2012-06-27 | Ucb Pharma Sa | Biological product |
| WO2014011955A2 (en) | 2012-07-12 | 2014-01-16 | Abbvie, Inc. | Il-1 binding proteins |
| CN104341501B (zh) * | 2013-07-29 | 2019-08-30 | 上海睿智化学研究有限公司 | 抗IL-1β人源化单克隆抗体及其制备方法和应用 |
| AU2015207464B2 (en) | 2014-01-20 | 2019-10-03 | Eveon | Process for reconstitution of a solid form of a pharmaceutical composition |
| GB201501613D0 (en) | 2015-01-30 | 2015-03-18 | Ucb Biopharma Sprl | Treatment of autoimmune disorders with CD154 antibodies |
| US9560393B2 (en) * | 2015-02-20 | 2017-01-31 | Disney Enterprises, Inc. | Media processing node |
| CN106349388B (zh) * | 2015-07-17 | 2021-04-02 | 上海佳文英莉生物技术有限公司 | 一种促细胞程序性坏死抗体及其应用 |
| MY206805A (en) | 2015-10-27 | 2025-01-08 | UCB Biopharma SRL | Methods of treatment using anti-il-17a/f antibodies |
| GB201616596D0 (en) | 2016-09-29 | 2016-11-16 | Nascient Limited | Epitope and antibodies |
| CN110818793A (zh) * | 2018-08-14 | 2020-02-21 | 中山康方生物医药有限公司 | 抗IL-1β的抗体、其药物组合物及其用途 |
| CN113383016B (zh) * | 2018-11-07 | 2022-09-13 | 三生国健药业(上海)股份有限公司 | 结合人IL-1β的抗体、其制备方法和用途 |
| GB201919062D0 (en) | 2019-12-20 | 2020-02-05 | Ucb Biopharma Sprl | Antibody |
| IL303294A (en) | 2020-12-07 | 2023-07-01 | UCB Biopharma SRL | Antibodies against interleukin-22 |
| AU2021395729A1 (en) | 2020-12-07 | 2023-07-13 | UCB Biopharma SRL | Multi-specific antibodies and antibody combinations |
| CA3218933A1 (en) | 2021-05-03 | 2022-11-10 | UCB Biopharma SRL | Antibodies |
| GB202111905D0 (en) | 2021-08-19 | 2021-10-06 | UCB Biopharma SRL | Antibodies |
| CN113855807A (zh) * | 2021-10-25 | 2021-12-31 | 孙良丹 | 一种试剂在制备治疗/抑制银屑病药物中的应用 |
| CN114524875B (zh) * | 2021-11-11 | 2023-07-25 | 江苏莱森生物科技研究院有限公司 | 偶联IL-1β单克隆抗体的纳米硅球及应用 |
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| EP0813423B1 (en) | 1995-01-23 | 2002-07-03 | Xenotech Incorporated | Composition to inhibit osteolysis and metastasis |
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| GB9625640D0 (en) | 1996-12-10 | 1997-01-29 | Celltech Therapeutics Ltd | Biological products |
| GB9720054D0 (en) * | 1997-09-19 | 1997-11-19 | Celltech Therapeutics Ltd | Biological products |
| GB0001448D0 (en) | 2000-01-21 | 2000-03-08 | Novartis Ag | Organic compounds |
| GB0013810D0 (en) * | 2000-06-06 | 2000-07-26 | Celltech Chiroscience Ltd | Biological products |
| GB0020685D0 (en) | 2000-08-22 | 2000-10-11 | Novartis Ag | Organic compounds |
| US20030026806A1 (en) * | 2000-10-27 | 2003-02-06 | Amgen Inc. | Antibodies and other selective IL-1 binding agents that allow binding to IL-1 receptor but not activation thereof |
| EP1423432A4 (en) * | 2001-07-26 | 2006-01-11 | Lilly Co Eli | ANTIBODIES TO INTERLEUKIN 1 BETA (IL-1BETA) |
| GB0303337D0 (en) | 2003-02-13 | 2003-03-19 | Celltech R&D Ltd | Biological products |
-
2003
- 2003-02-13 GB GBGB0303337.0A patent/GB0303337D0/en not_active Ceased
-
2004
- 2004-02-06 AT AT04708808T patent/ATE525397T1/de active
- 2004-02-06 WO PCT/GB2004/000463 patent/WO2004072116A2/en not_active Ceased
- 2004-02-06 EA EA200501286A patent/EA200501286A1/ru unknown
- 2004-02-06 KR KR1020057013813A patent/KR20050099509A/ko not_active Withdrawn
- 2004-02-06 AU AU2004210776A patent/AU2004210776B2/en not_active Ceased
- 2004-02-06 CA CA2515474A patent/CA2515474C/en not_active Expired - Fee Related
- 2004-02-06 BR BR0407233-2A patent/BRPI0407233A/pt not_active Application Discontinuation
- 2004-02-06 EP EP04708808A patent/EP1597282B1/en not_active Expired - Lifetime
- 2004-02-06 DK DK04708808.3T patent/DK1597282T3/da active
- 2004-02-06 PT PT04708808T patent/PT1597282E/pt unknown
- 2004-02-06 SI SI200431797T patent/SI1597282T1/sl unknown
- 2004-02-06 CN CNA2004800033654A patent/CN1745103A/zh active Pending
- 2004-02-06 US US10/544,911 patent/US7608694B2/en not_active Expired - Fee Related
- 2004-02-06 ES ES04708808T patent/ES2373953T3/es not_active Expired - Lifetime
- 2004-02-06 JP JP2006502246A patent/JP4668896B2/ja not_active Expired - Fee Related
- 2004-02-06 EP EP10182246A patent/EP2287193A1/en not_active Withdrawn
- 2004-02-06 MX MXPA05007392A patent/MXPA05007392A/es not_active Application Discontinuation
- 2004-02-06 PL PL378412A patent/PL378412A1/pl unknown
- 2004-02-09 PE PE2004000142A patent/PE20040947A1/es not_active Application Discontinuation
- 2004-02-12 AR ARP040100431A patent/AR043159A1/es unknown
- 2004-02-12 TW TW093103340A patent/TW200505942A/zh unknown
- 2004-02-12 CL CL200400259A patent/CL2004000259A1/es unknown
-
2005
- 2005-09-07 IS IS8013A patent/IS8013A/is unknown
- 2005-09-12 NO NO20054223A patent/NO20054223L/no unknown
- 2005-09-13 EC EC2005006014A patent/ECSP056014A/es unknown
-
2009
- 2009-09-29 US US12/569,700 patent/US8465744B2/en not_active Expired - Fee Related
-
2010
- 2010-06-04 JP JP2010128372A patent/JP2010246553A/ja active Pending
-
2011
- 2011-12-21 CY CY20111101274T patent/CY1112507T1/el unknown
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