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DK1414414T3 - Fremgangsmåde til termodynamisk aktivering af vand-uoplöselige lægemidler hvormed tværbundne polymerer er ladet - Google Patents

Fremgangsmåde til termodynamisk aktivering af vand-uoplöselige lægemidler hvormed tværbundne polymerer er ladet

Info

Publication number
DK1414414T3
DK1414414T3 DK02754615T DK02754615T DK1414414T3 DK 1414414 T3 DK1414414 T3 DK 1414414T3 DK 02754615 T DK02754615 T DK 02754615T DK 02754615 T DK02754615 T DK 02754615T DK 1414414 T3 DK1414414 T3 DK 1414414T3
Authority
DK
Denmark
Prior art keywords
water
cross
drug
charged
insoluble drugs
Prior art date
Application number
DK02754615T
Other languages
Danish (da)
English (en)
Inventor
Massimo Bresciani
Lorenzo Magarotto
Luca Dobetti
Original Assignee
Eurand Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eurand Pharmaceuticals Ltd filed Critical Eurand Pharmaceuticals Ltd
Application granted granted Critical
Publication of DK1414414T3 publication Critical patent/DK1414414T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
DK02754615T 2001-06-29 2002-06-03 Fremgangsmåde til termodynamisk aktivering af vand-uoplöselige lægemidler hvormed tværbundne polymerer er ladet DK1414414T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IE20010628 2001-06-29
PCT/EP2002/006052 WO2003002097A1 (fr) 2001-06-29 2002-06-03 Procede d'activation thermodynamique de medicaments insolubles dans l'eau charges dans des polymeres reticules

Publications (1)

Publication Number Publication Date
DK1414414T3 true DK1414414T3 (da) 2008-03-03

Family

ID=11042810

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02754615T DK1414414T3 (da) 2001-06-29 2002-06-03 Fremgangsmåde til termodynamisk aktivering af vand-uoplöselige lægemidler hvormed tværbundne polymerer er ladet

Country Status (11)

Country Link
US (1) US8889182B2 (fr)
EP (1) EP1414414B1 (fr)
JP (1) JP2005503360A (fr)
AT (1) ATE377413T1 (fr)
AU (1) AU2002321061B2 (fr)
CA (1) CA2452575C (fr)
DE (1) DE60223382T2 (fr)
DK (1) DK1414414T3 (fr)
ES (1) ES2295379T3 (fr)
NZ (1) NZ530826A (fr)
WO (1) WO2003002097A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4865990B2 (ja) * 2002-04-12 2012-02-01 エラン ファーマ インターナショナル，リミティド ナノ粒子メゲストロール製剤
US9101540B2 (en) 2002-04-12 2015-08-11 Alkermes Pharma Ireland Limited Nanoparticulate megestrol formulations
BRPI0412263B1 (pt) 2003-07-22 2019-10-15 Arena Pharmaceuticals, Inc. Derivados de diaril e aril heteroaril uréia, uso e composição farmacêutica contendo os mesmos, bem como processo para preparação da dita composição
US7535456B2 (en) * 2004-04-30 2009-05-19 Hillcrest Laboratories, Inc. Methods and devices for removing unintentional movement in 3D pointing devices
GB0516604D0 (en) * 2005-08-12 2005-09-21 Sandoz Ag Rapidly dispersing/disintegrating compositions
TWI415845B (zh) 2006-10-03 2013-11-21 Arena Pharm Inc 用於治療與５-ｈｔ2ａ血清素受體相關聯病症之作為５-ｈｔ2ａ血清素受體之調節劑的吡唑衍生物
JP5393677B2 (ja) 2007-08-15 2014-01-22 アリーナ ファーマシューティカルズ， インコーポレイテッド ５−ＨＴ２Ａセロトニン受容体に関連した障害の治療のための５−ＨＴ２Ａセロトニン受容体のモジュレーターとしてのイミダゾ［１，２−ａ］ピリジン誘導体
US20110021538A1 (en) 2008-04-02 2011-01-27 Arena Pharmaceuticals, Inc. Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
EP2293779A1 (fr) * 2008-04-24 2011-03-16 Evestra, Inc. Formes galéniques contraceptives orales renfermant un progestogène dispersé dans un polymère gastrorésistant et renfermant en outre un strogène
US9126946B2 (en) 2008-10-28 2015-09-08 Arena Pharmaceuticals, Inc. Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)urea and crystalline forms related thereto
US9034911B2 (en) 2008-10-28 2015-05-19 Arena Pharmaceuticals, Inc. Composition of a 5-HT2A serotonin receptor modulator useful for the treatment of disorders related thereto
ITMI20120092A1 (it) * 2012-01-26 2013-07-27 Micro Macinazione S A Compositi di inclusione farmaco-carrier preparati con processo di attivazione meccano-chimica mediante mulini a getto di fluido ad alta energia
WO2016201373A1 (fr) 2015-06-12 2016-12-15 Axovant Sciences Ltd. Dérivés de diaryl et arylhétéroaryl urée utiles pour la prophylaxie et le traitement du trouble du comportement en sommeil rem
CA2992518A1 (fr) 2015-07-15 2017-01-19 Axovant Sciences Gmbh Derives d'arylheretoaryl uree en tant que modulateurs du recepteur serotoninergique 5-ht2a utiles pour la prophylaxie et le traitement d'hallucinations associees a une maladie neurodegenerative

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2634004B2 (de) 1976-07-29 1978-08-10 Bernhard Dr. 8000 Muenchen Lippold Verfahren zur Beschleunigung der Auflösung und Verbesserung der Löslichkeit von schlechtlöslichen zur peroralen Verabreichung bestimmten Arzneistoffen
DE3320583A1 (de) 1983-06-08 1984-12-13 Dr. Karl Thomae Gmbh, 7950 Biberach Neue galenische zubereitungsformen von oralen antidiabetika und verfahren zu ihrer herstellung
GB8403359D0 (en) * 1984-02-08 1984-03-14 Erba Farmitalia Pharmaceutical compositions
US5225192A (en) * 1988-10-17 1993-07-06 Vectorpharma International S.P.A. Poorly soluble medicaments supported on polymer substances in a form suitable for increasing their dissolving rate
IT1227626B (it) * 1988-11-28 1991-04-23 Vectorpharma Int Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazione
IT1241417B (it) * 1990-03-06 1994-01-14 Vectorpharma Int Composizioni terapeutiche a rilascio controllato di farmaci supportatisu polimeri reticolati e rivestiti con film polimerici,e loro processodi preparazione
IT1246188B (it) * 1990-07-27 1994-11-16 Resa Farma Procedimento per la preparazione di composizioni farmaceutiche aventi aumentata velocita' di dissoluzione della sostanza attiva e composizioni ottenute.
IT1298574B1 (it) * 1998-02-06 2000-01-12 Vectorpharma Int Composizioni farmaceutiche in forma di microparticelle a base polimerica ottenute mediante estrusione e sferonizzazione

Also Published As

Publication number Publication date
ES2295379T3 (es) 2008-04-16
WO2003002097A1 (fr) 2003-01-09
CA2452575A1 (fr) 2003-01-09
DE60223382D1 (de) 2007-12-20
ATE377413T1 (de) 2007-11-15
DE60223382T2 (de) 2008-09-11
US20040213840A1 (en) 2004-10-28
NZ530826A (en) 2004-09-24
EP1414414B1 (fr) 2007-11-07
EP1414414A1 (fr) 2004-05-06
AU2002321061B2 (en) 2006-08-24
US8889182B2 (en) 2014-11-18
CA2452575C (fr) 2010-11-02
JP2005503360A (ja) 2005-02-03

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