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DK1409984T4 - Fremgangsmåder og reagenser til detektering af endotoxin - Google Patents

Fremgangsmåder og reagenser til detektering af endotoxin

Info

Publication number
DK1409984T4
DK1409984T4 DK02768293.9T DK02768293T DK1409984T4 DK 1409984 T4 DK1409984 T4 DK 1409984T4 DK 02768293 T DK02768293 T DK 02768293T DK 1409984 T4 DK1409984 T4 DK 1409984T4
Authority
DK
Denmark
Prior art keywords
reagents
methods
endotoxin detection
factor
endotoxin
Prior art date
Application number
DK02768293.9T
Other languages
English (en)
Other versions
DK1409984T3 (da
Inventor
Michael Pepe
Lin Chen
Original Assignee
Lonza Walkersville Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23162060&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1409984(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lonza Walkersville Inc filed Critical Lonza Walkersville Inc
Publication of DK1409984T3 publication Critical patent/DK1409984T3/da
Application granted granted Critical
Publication of DK1409984T4 publication Critical patent/DK1409984T4/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/50—Lipopolysaccharides; LPS

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
DK02768293.9T 2001-06-28 2002-06-28 Fremgangsmåder og reagenser til detektering af endotoxin DK1409984T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30112501P 2001-06-28 2001-06-28
PCT/US2002/020395 WO2003002976A2 (en) 2001-06-28 2002-06-28 Methods and reagents for detecting endotoxin

Publications (2)

Publication Number Publication Date
DK1409984T3 DK1409984T3 (da) 2009-11-16
DK1409984T4 true DK1409984T4 (da) 2013-07-08

Family

ID=23162060

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02768293.9T DK1409984T4 (da) 2001-06-28 2002-06-28 Fremgangsmåder og reagenser til detektering af endotoxin

Country Status (14)

Country Link
US (2) US6849426B2 (da)
EP (1) EP1409984B2 (da)
JP (2) JP2005500520A (da)
CN (1) CN100390193C (da)
AT (1) ATE437886T1 (da)
AU (1) AU2002330860C1 (da)
BR (1) BRPI0210681B8 (da)
CY (1) CY1109554T1 (da)
DE (1) DE60233142D1 (da)
DK (1) DK1409984T4 (da)
ES (1) ES2329664T5 (da)
MX (1) MXPA03012032A (da)
PT (1) PT1409984E (da)
WO (1) WO2003002976A2 (da)

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CN1318848C (zh) * 2003-11-26 2007-05-30 中国科学院大连化学物理研究所 一种用于细菌内毒素鲎试验检测法的缓冲液及其制备方法
JP5495490B2 (ja) * 2004-05-07 2014-05-21 アレス トレーディング エスエイ ランダム共重合体を用いる疾患の治療方法
US20060101539A1 (en) * 2004-11-05 2006-05-11 Ainley William M Cryopreservation of cells
US20060223074A1 (en) * 2005-04-05 2006-10-05 Bunch Thomas A Spotting compositions and methods of use thereof
US9233846B2 (en) * 2005-10-14 2016-01-12 The Regents Of The University Of California Formation and encapsulation of molecular bilayer and monolayer membranes
WO2007047498A2 (en) * 2005-10-14 2007-04-26 The Regents Of The University Of California Formation and encapsulation of molecular bilayer and monolayer membranes
CN101454448A (zh) * 2006-07-07 2009-06-10 生化学工业株式会社 凝固酶原以及使用所述酶检测内毒素或(1→3)-β-D-葡聚糖的方法
DE602007008125D1 (de) 2006-10-31 2010-09-09 Surmodics Pharmaceuticals Inc Kugelförmige polymer-teilchen
US9090737B2 (en) * 2007-11-13 2015-07-28 Surmodics, Inc. Viscous terpolymers as drug delivery platform
WO2009143425A1 (en) * 2008-05-22 2009-11-26 The Regents Of The University Of California Membrane precursors and membranes formed therefrom
US7846678B2 (en) * 2008-08-18 2010-12-07 BioDtech, Inc. Enhancing endotoxin detection
CA2741550C (en) 2008-10-29 2018-12-04 T2 Biosystems, Inc. Nmr detection of coagulation time
US9415197B2 (en) * 2008-12-23 2016-08-16 Surmodics, Inc. Implantable suction cup composites and implants comprising same
US8951546B2 (en) * 2008-12-23 2015-02-10 Surmodics Pharmaceuticals, Inc. Flexible implantable composites and implants comprising same
US20100168807A1 (en) * 2008-12-23 2010-07-01 Burton Kevin W Bioactive terpolymer compositions and methods of making and using same
US8974808B2 (en) 2008-12-23 2015-03-10 Surmodics, Inc. Elastic implantable composites and implants comprising same
US9480643B2 (en) 2008-12-23 2016-11-01 Surmodics Pharmaceuticals, Inc. Implantable composites and implants comprising same
US10473663B2 (en) * 2009-06-26 2019-11-12 Charles River Laboratories, Inc. Heat-treated limulus amebocyte lysates
EP2521650A4 (en) 2010-01-05 2013-05-15 Univ California DROPLYING TUBE LAYERING BY TREATMENT PROCEDURE FOR RIVETED LIQUIDS
WO2011146463A2 (en) * 2010-05-17 2011-11-24 BioDtech, Inc. Enhancing endotoxin detection
WO2012030823A1 (en) 2010-08-30 2012-03-08 Surmodics Pharmaceuticals, Inc. Biodegradable terpolymers and terpolymer blends as pressure-sensitive adhesives
WO2012118800A2 (en) * 2011-02-28 2012-09-07 BioDtech, Inc. Enhancing endotoxin detection
JP2014510898A (ja) 2011-02-28 2014-05-01 生化学工業株式会社 エンドトキシン測定剤
EP3321373B1 (en) 2011-07-13 2020-01-15 T2 Biosystems, Inc. Nmr methods for monitoring blood clot formation
US10620205B2 (en) 2011-09-21 2020-04-14 T2 Biosystems, Inc. NMR methods for endotoxin analysis
US9150598B2 (en) 2011-10-05 2015-10-06 The Regents Of The University Of California Masking apertures enabling automation and solution exchange in sessile bilayers
CU24073B1 (es) 2011-12-27 2015-01-29 Ct De Investigación Y Desarrollo De Medicamentos Cidem COMPOSICIÓN A PARTIR DE EXTRACTO DE HEMOCITOS DE LANGOSTA PARA LA DETECCIÓN DE LIPOPOLISACÁRIDOS, PEPTIDOGLICANOS Y 1,3-ß-D-GLUCANOS
CN103290041A (zh) * 2012-02-27 2013-09-11 上海拜生生物科技有限公司 中国鲎c因子原核及昆虫杆状病毒重组表达载体的构建
CN103290054A (zh) * 2012-02-27 2013-09-11 上海拜生生物科技有限公司 应用昆虫细胞表达重组的中国鲎c因子
CN103290042A (zh) * 2012-02-27 2013-09-11 上海拜生生物科技有限公司 内毒素检测及去除关键分子中国鲎c因子克隆和序列分析
EP2740791A1 (en) 2012-12-05 2014-06-11 MicroCoat Biotechnologie GmbH Method for recombinant production of horseshoe crab Factor C protein in protozoa
EP2929047A4 (en) 2012-12-07 2016-08-03 T2 Biosystems Inc Methods for monitoring tight clot formation
SG11201504564TA (en) * 2012-12-10 2015-08-28 Seikagaku Kogyo Co Ltd Novel recombinant factor c and method for producing the same, and method for measuring endotoxin
CN104356211B (zh) * 2014-09-22 2017-08-29 山东信得科技股份有限公司 一种应用Triton X‑114和尿囊素去除重组蛋白质溶液中内毒素的方法
ES2978162T3 (es) 2016-10-18 2024-09-06 Seikagaku Kogyo Co Ltd Método para producir un agente de detección de endotoxinas que comprende el factor C recombinante de Limulus y su uso
CN111077307B (zh) * 2018-10-21 2022-08-23 厦门鲎试剂生物科技股份有限公司 一种用革兰氏阴性细菌感染快速检测脓毒病的新方法
JP7349104B2 (ja) * 2019-11-13 2023-09-22 株式会社島津製作所 ベロ毒素の検出方法
EP4137817A4 (en) 2020-04-16 2024-08-07 Kikkoman Corporation HYDROLASE-USED METHOD FOR TRACE SUBSTANCE MEASUREMENT
CN119881319B (zh) * 2024-12-04 2025-11-28 苏州鲎源生物科技有限公司 一种重组鲎三因子试剂及试剂盒

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Publication number Priority date Publication date Assignee Title
US4322217A (en) * 1980-06-27 1982-03-30 Mallinckrodt, Inc. Process for preparing Limulus lysate
BE889407A (fr) * 1980-06-27 1981-10-16 Mallinckrodt Inc Amelioration du procede de preparation d'un lysat de limule
JPH03187378A (ja) * 1989-12-16 1991-08-15 Taiyo Fishery Co Ltd 酵素前駆体ファクターｃの調整方法及びその調整試薬
JP3524120B2 (ja) * 1992-05-08 2004-05-10 生化学工業株式会社 前処理剤、前処理方法、前処理された試料による測定法、測定用キット及び試料の判定方法
JP3402476B2 (ja) * 1992-08-24 2003-05-06 生化学工業株式会社 リポ多糖結合性タンパク質及びその製造法
JP3429036B2 (ja) * 1993-09-30 2003-07-22 生化学工業株式会社 エンドトキシンの特異的測定剤
US5716834A (en) * 1994-08-19 1998-02-10 National University Of Singapore Cloned factor C cDNA of the Singapore horseshoe crab, Carcinoscorpius rotundicauda and purification of factor C proenzyme
JP3869094B2 (ja) * 1996-10-21 2007-01-17 生化学工業株式会社 エンドトキシンの測定方法
EP0837330B1 (en) * 1996-10-21 2005-08-24 Seikagaku Corporation Method for measuring Endotoxin
EP1015609B1 (en) * 1997-09-19 2004-09-01 National University Of Singapore A novel generation of cloned horseshoe crab recombinant factor c for detection and removal of endotoxin
JP3957386B2 (ja) * 1998-01-08 2007-08-15 生化学工業株式会社 昆虫体液反応性物質の特異的測定剤及び測定方法
WO2001027289A2 (en) * 1999-10-15 2001-04-19 National University Of Singapore Recombinant proteins and peptides for endotoxin biosensors, endotoxin removal, and anti-microbial and anti-endotoxin therapeutics

Also Published As

Publication number Publication date
ATE437886T1 (de) 2009-08-15
WO2003002976A3 (en) 2003-05-15
PT1409984E (pt) 2009-10-29
US20030054432A1 (en) 2003-03-20
EP1409984A4 (en) 2006-07-19
AU2002330860C1 (en) 2009-05-14
WO2003002976A2 (en) 2003-01-09
US6849426B2 (en) 2005-02-01
BRPI0210681B8 (pt) 2021-07-27
JP2009150903A (ja) 2009-07-09
JP5039729B2 (ja) 2012-10-03
BRPI0210681B1 (pt) 2016-03-29
CN1529711A (zh) 2004-09-15
BR0210681A (pt) 2004-09-21
JP2005500520A (ja) 2005-01-06
EP1409984A2 (en) 2004-04-21
CY1109554T1 (el) 2014-08-13
DE60233142D1 (de) 2009-09-10
MXPA03012032A (es) 2005-07-01
DK1409984T3 (da) 2009-11-16
EP1409984B1 (en) 2009-07-29
US20040235080A1 (en) 2004-11-25
ES2329664T5 (es) 2013-08-28
ES2329664T3 (es) 2009-11-30
CN100390193C (zh) 2008-05-28
EP1409984B2 (en) 2013-04-10
AU2002330860B2 (en) 2008-12-04

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