DK1401413T3 - Anvendelse af tyrosinkinaseinhibitorer til behandling af allergiske sygdomme - Google Patents
Anvendelse af tyrosinkinaseinhibitorer til behandling af allergiske sygdommeInfo
- Publication number
- DK1401413T3 DK1401413T3 DK02755512T DK02755512T DK1401413T3 DK 1401413 T3 DK1401413 T3 DK 1401413T3 DK 02755512 T DK02755512 T DK 02755512T DK 02755512 T DK02755512 T DK 02755512T DK 1401413 T3 DK1401413 T3 DK 1401413T3
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- tyrosine kinase
- allergic diseases
- kinase inhibitors
- inhibitor
- Prior art date
Links
- 208000026935 allergic disease Diseases 0.000 title abstract 2
- 229940121358 tyrosine kinase inhibitor Drugs 0.000 title abstract 2
- 239000005483 tyrosine kinase inhibitor Substances 0.000 title abstract 2
- 108010002386 Interleukin-3 Proteins 0.000 abstract 2
- 229940124204 C-kit inhibitor Drugs 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 150000004917 tyrosine kinase inhibitor derivatives Chemical class 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
- A61K31/015—Hydrocarbons carbocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30140801P | 2001-06-29 | 2001-06-29 | |
| PCT/IB2002/003297 WO2003002106A2 (fr) | 2001-06-29 | 2002-06-28 | Utilisation d'inhibiteurs de tyrosine kinase dans le traitement de maladies allergiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1401413T3 true DK1401413T3 (da) | 2007-03-26 |
Family
ID=23163215
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02755512T DK1401413T3 (da) | 2001-06-29 | 2002-06-28 | Anvendelse af tyrosinkinaseinhibitorer til behandling af allergiske sygdomme |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7700610B2 (fr) |
| EP (1) | EP1401413B1 (fr) |
| JP (1) | JP2004537536A (fr) |
| AT (1) | ATE345839T1 (fr) |
| CA (1) | CA2452371A1 (fr) |
| CY (1) | CY1106011T1 (fr) |
| DE (1) | DE60216281T2 (fr) |
| DK (1) | DK1401413T3 (fr) |
| ES (1) | ES2274993T3 (fr) |
| PT (1) | PT1401413E (fr) |
| WO (1) | WO2003002106A2 (fr) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2452368A1 (fr) | 2001-06-29 | 2003-01-09 | Ab Science | Nouveaux inhibiteurs selectifs puissants et non toxiques de c-kit |
| WO2003004007A2 (fr) | 2001-06-29 | 2003-01-16 | Ab Science | Utilisation d'inhibiteurs de tyrosine kinases pour traiter les maladies intestinales inflammatoires (mii) |
| DK1401413T3 (da) | 2001-06-29 | 2007-03-26 | Ab Science | Anvendelse af tyrosinkinaseinhibitorer til behandling af allergiske sygdomme |
| EP1401415B1 (fr) * | 2001-06-29 | 2006-06-21 | AB Science | Utilisation de derives de la n-phenyl-2-pyrimidine-amine destines au traitement de maladies inflammatoires |
| EP1401412A2 (fr) * | 2001-06-29 | 2004-03-31 | AB Science | Utilisation d'inhibiteurs de materiel c, puissants, selectifs et non toxiques pour traiter l'angiogenese tumorale |
| ATE401079T1 (de) * | 2001-06-29 | 2008-08-15 | Ab Science | Die verwendung von c-kithemmern zur behandlung von autoimmunerkrankungen |
| US20040242601A1 (en) * | 2001-09-20 | 2004-12-02 | Alain Moussy | Use of potent, selective and non toxic c-kit inhibitors for treating interstitial cystitis |
| ATE401078T1 (de) * | 2001-09-20 | 2008-08-15 | Ab Science | Die verwendung von c-kithemmern zur förderung des haarwuchses |
| WO2003072090A2 (fr) * | 2002-02-27 | 2003-09-04 | Ab Science | Utilisation d'inhibiteurs de tyrosine kinase pour le traitement de troubles du snc |
| US20060052387A1 (en) * | 2002-06-26 | 2006-03-09 | Marsh Clay B | Organic compounds |
| EP1525200B1 (fr) | 2002-08-02 | 2007-10-10 | AB Science | 2-(3-aminoaryl)amino-4-aryl-thiazoles et leur utilisation en tant que inhibiteurs de c-kit |
| US8450302B2 (en) | 2002-08-02 | 2013-05-28 | Ab Science | 2-(3-aminoaryl) amino-4-aryl-thiazoles and their use as c-kit inhibitors |
| ATE465731T1 (de) | 2003-10-23 | 2010-05-15 | Ab Science | 2-aminoaryloxazol-verbindungen als tyrosinkinase- hemmer |
| WO2005115385A1 (fr) * | 2004-05-24 | 2005-12-08 | Ab Science | Utilisation d'inhibiteurs de c-kit pour le traitement de l'acne |
| AU2006231929B2 (en) | 2005-04-04 | 2012-09-06 | Ab Science | Substituted oxazole derivatives and their use as tyrosine kinase inhibitors |
| HRP20110709T1 (hr) | 2007-02-13 | 2011-11-30 | Ab Science | Postupak sinteze spojeva 2-aminotioazola kao inhibitora kinaza |
| EP2434961B1 (fr) | 2009-05-29 | 2015-01-14 | Xlumena, Inc. | Appareil et méthode de déploiement d'une endoprothèse à travers des couches de tissu adjacent |
| CN103717591B (zh) | 2011-07-27 | 2016-08-24 | Ab科学有限公司 | 作为选择性蛋白激酶(c-kit)抑制剂的噁唑和噻唑衍生物 |
| US20150044288A1 (en) | 2013-07-31 | 2015-02-12 | Windward Pharma, Inc. | Aerosol tyrosine kinase inhibitor compounds and uses thereof |
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| US3558653A (en) | 1968-05-20 | 1971-01-26 | Searle & Co | Dialkylaminoalkyl-indolines |
| US3725403A (en) | 1970-10-20 | 1973-04-03 | Squibb & Sons Inc | Benzothiazine derivatives |
| US4438267A (en) | 1980-11-11 | 1984-03-20 | Daluge Susan M | Monoheteroring compounds and their use |
| GB8913708D0 (en) | 1989-06-14 | 1989-08-02 | Unilever Plc | Cosmetic composition |
| US5308839A (en) | 1989-12-04 | 1994-05-03 | The Research Foundation Of State University Of New York | Composition comprising non-steroidal anti-inflammatory agent tenidap and effectively non-antibacterial tetracycline |
| TW225528B (fr) | 1992-04-03 | 1994-06-21 | Ciba Geigy Ag | |
| US5521184A (en) | 1992-04-03 | 1996-05-28 | Ciba-Geigy Corporation | Pyrimidine derivatives and processes for the preparation thereof |
| US5639757A (en) | 1995-05-23 | 1997-06-17 | Pfizer Inc. | 4-aminopyrrolo[2,3-d]pyrimidines as tyrosine kinase inhibitors |
| US5880141A (en) | 1995-06-07 | 1999-03-09 | Sugen, Inc. | Benzylidene-Z-indoline compounds for the treatment of disease |
| GB9523675D0 (en) * | 1995-11-20 | 1996-01-24 | Celltech Therapeutics Ltd | Chemical compounds |
| JP2000508894A (ja) | 1996-04-10 | 2000-07-18 | ヒューマン ジノーム サイエンシーズ,インコーポレイテッド | 細胞外/上皮増殖因子hcaba58x |
| GB9622363D0 (en) | 1996-10-28 | 1997-01-08 | Celltech Therapeutics Ltd | Chemical compounds |
| AU6163398A (en) | 1997-02-11 | 1998-08-26 | Merck & Co., Inc. | Identification of inhibitors of protein tyrosine kinase 2 |
| CA2283961A1 (fr) | 1997-03-19 | 1998-09-24 | Basf Aktiengesellschaft | Pyrrolo [2,3] pyrimidines et leur utilisation comme inhibiteurs de la tyrosine kinase |
| WO1998050356A1 (fr) | 1997-05-07 | 1998-11-12 | Sugen, Inc. | Derives de 2-indolinone utilises en tant que modulateurs de l'activite de la proteine kinase |
| WO1998055152A1 (fr) | 1997-06-06 | 1998-12-10 | Baylor College Of Medicine | Mecanisme secretoire des mastocytes utilise comme cible en vue du developpement de medicaments antiallergiques |
| US6114371A (en) | 1997-06-20 | 2000-09-05 | Sugen, Inc. | 3-(cyclohexanoheteroarylidenyl)-2-indolinone protein tyrosine kinase inhibitors |
| CO4940418A1 (es) | 1997-07-18 | 2000-07-24 | Novartis Ag | Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso |
| WO1999011643A1 (fr) | 1997-09-02 | 1999-03-11 | Du Pont Pharmaceuticals Company | Pyridines a cycle fusionne et a substitution heterocyclyle, antagonistes du facteur de liberation de la cortitropine (crf), utiles dans le traitement des troubles lies au snc et au stress |
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| EP1082122A4 (fr) | 1998-05-27 | 2003-04-09 | Sherwood L Gorbach | Isoflavonoides utiles dans le traitement et la prevention de maux de tete du type migraine |
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| US6989248B2 (en) | 1999-05-06 | 2006-01-24 | The Trustees Of Columbia University In The City Of New York | Methods of use of compounds which inhibit the stem cell signaling pathway |
| EP1206265B1 (fr) | 1999-06-30 | 2003-11-12 | Merck & Co., Inc. | Composes inhibiteurs de la src kinase |
| WO2001016130A1 (fr) | 1999-08-27 | 2001-03-08 | Boehringer Ingelheim Pharma Kg | Indolinones substituees utilisees comme inhibiteurs de la tyrosine kinase |
| UA75054C2 (uk) | 1999-10-13 | 2006-03-15 | Бьорінгер Інгельхайм Фарма Гмбх & Ко. Кг | Заміщені в положенні 6 індолінони, їх одержання та їх застосування як лікарського засобу |
| US6762180B1 (en) | 1999-10-13 | 2004-07-13 | Boehringer Ingelheim Pharma Kg | Substituted indolines which inhibit receptor tyrosine kinases |
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| WO2001047950A2 (fr) | 1999-12-23 | 2001-07-05 | Universite De Geneve | Signal de tri basolateral et inhibiteurs correspondants |
| US6339100B1 (en) | 1999-12-29 | 2002-01-15 | The Trustees Of Columbia University In The City Of New York | Methods for inhibiting mastocytosis |
| AU2001237041B9 (en) | 2000-02-17 | 2005-07-28 | Amgen Inc. | Kinase inhibitors |
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| KR100885129B1 (ko) * | 2000-10-27 | 2009-02-23 | 노파르티스 아게 | 위장관의 기질 종양의 치료 |
| GEP20063915B (en) | 2000-11-17 | 2006-09-11 | Bristol Myers Squibb Co | PYRROLOTRIAZINE COMPOUNDS USEFUL AS KINASE INHIBITORS AND USE THEREOF FOR TREATING p38 KINASE-ASSOCIATED CONDITIONS |
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| JP2005503361A (ja) | 2001-06-29 | 2005-02-03 | アブ サイエンス | 肥満細胞症治療のための強力で選択的かつ非毒性のc−kit阻害剤の使用 |
| DK1401413T3 (da) | 2001-06-29 | 2007-03-26 | Ab Science | Anvendelse af tyrosinkinaseinhibitorer til behandling af allergiske sygdomme |
| US20040259892A1 (en) | 2001-06-29 | 2004-12-23 | Alain Moussy | Use of tyrosine kinase inhibitors for treating multiple sclerosis (ms) |
| WO2003004007A2 (fr) | 2001-06-29 | 2003-01-16 | Ab Science | Utilisation d'inhibiteurs de tyrosine kinases pour traiter les maladies intestinales inflammatoires (mii) |
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| EP1401412A2 (fr) | 2001-06-29 | 2004-03-31 | AB Science | Utilisation d'inhibiteurs de materiel c, puissants, selectifs et non toxiques pour traiter l'angiogenese tumorale |
| CA2452368A1 (fr) | 2001-06-29 | 2003-01-09 | Ab Science | Nouveaux inhibiteurs selectifs puissants et non toxiques de c-kit |
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| ATE401078T1 (de) | 2001-09-20 | 2008-08-15 | Ab Science | Die verwendung von c-kithemmern zur förderung des haarwuchses |
| DE60225590T2 (de) | 2001-09-20 | 2008-09-25 | Ab Science | C-kithemmer zur behandlung von bakteriellen infektionen |
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| US20060275769A1 (en) | 2003-01-06 | 2006-12-07 | Oregon Health & Science University | Methods of treatment and diagnosis of kaposi's sarcoma (ks) and ks related diseases |
-
2002
- 2002-06-28 DK DK02755512T patent/DK1401413T3/da active
- 2002-06-28 CA CA002452371A patent/CA2452371A1/fr not_active Abandoned
- 2002-06-28 US US10/482,035 patent/US7700610B2/en not_active Expired - Lifetime
- 2002-06-28 JP JP2003508345A patent/JP2004537536A/ja active Pending
- 2002-06-28 DE DE60216281T patent/DE60216281T2/de not_active Expired - Lifetime
- 2002-06-28 EP EP02755512A patent/EP1401413B1/fr not_active Expired - Lifetime
- 2002-06-28 WO PCT/IB2002/003297 patent/WO2003002106A2/fr not_active Ceased
- 2002-06-28 AT AT02755512T patent/ATE345839T1/de not_active IP Right Cessation
- 2002-06-28 PT PT02755512T patent/PT1401413E/pt unknown
- 2002-06-28 ES ES02755512T patent/ES2274993T3/es not_active Expired - Lifetime
-
2007
- 2007-02-12 CY CY20071100187T patent/CY1106011T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US7700610B2 (en) | 2010-04-20 |
| EP1401413B1 (fr) | 2006-11-22 |
| DE60216281T2 (de) | 2007-07-05 |
| WO2003002106A2 (fr) | 2003-01-09 |
| DE60216281D1 (de) | 2007-01-04 |
| EP1401413A2 (fr) | 2004-03-31 |
| CY1106011T1 (el) | 2011-04-06 |
| US20040259893A1 (en) | 2004-12-23 |
| CA2452371A1 (fr) | 2003-01-09 |
| WO2003002106A3 (fr) | 2003-05-30 |
| PT1401413E (pt) | 2007-02-28 |
| JP2004537536A (ja) | 2004-12-16 |
| ES2274993T3 (es) | 2007-06-01 |
| ATE345839T1 (de) | 2006-12-15 |
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