DK1485363T3 - Cykliske amider - Google Patents
Cykliske amiderInfo
- Publication number
- DK1485363T3 DK1485363T3 DK03708178T DK03708178T DK1485363T3 DK 1485363 T3 DK1485363 T3 DK 1485363T3 DK 03708178 T DK03708178 T DK 03708178T DK 03708178 T DK03708178 T DK 03708178T DK 1485363 T3 DK1485363 T3 DK 1485363T3
- Authority
- DK
- Denmark
- Prior art keywords
- cyclic amides
- psychoses
- schizophrenia
- huntington
- epilepsy
- Prior art date
Links
- 150000003950 cyclic amides Chemical class 0.000 title 1
- 208000026106 cerebrovascular disease Diseases 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 206010008120 Cerebral ischaemia Diseases 0.000 abstract 1
- 208000023105 Huntington disease Diseases 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 208000028017 Psychotic disease Diseases 0.000 abstract 1
- 239000003194 amino acid receptor blocking agent Substances 0.000 abstract 1
- 206010008118 cerebral infarction Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 230000007574 infarction Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10210779A DE10210779A1 (de) | 2002-03-12 | 2002-03-12 | Cyclische Amide |
| PCT/EP2003/002224 WO2003076420A1 (de) | 2002-03-12 | 2003-03-05 | Cyclische amide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1485363T3 true DK1485363T3 (da) | 2009-02-02 |
Family
ID=27797699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03708178T DK1485363T3 (da) | 2002-03-12 | 2003-03-05 | Cykliske amider |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7816376B2 (da) |
| EP (1) | EP1485363B1 (da) |
| JP (1) | JP2005519953A (da) |
| CN (1) | CN1642927A (da) |
| AT (1) | ATE410418T1 (da) |
| AU (1) | AU2003212305B2 (da) |
| CA (1) | CA2478945A1 (da) |
| CY (1) | CY1108674T1 (da) |
| DE (2) | DE10210779A1 (da) |
| DK (1) | DK1485363T3 (da) |
| ES (1) | ES2315483T3 (da) |
| PL (1) | PL371215A1 (da) |
| PT (1) | PT1485363E (da) |
| RU (1) | RU2004130426A (da) |
| SI (1) | SI1485363T1 (da) |
| WO (1) | WO2003076420A1 (da) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0315166A (pt) * | 2002-10-11 | 2005-08-16 | Astrazeneca Ab | Uso de um composto ou de um sal farmaceuticamente aceitável do mesmo, composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, método para produzir um efeito inibidor de 11betahsd1 em um animal de sangue quente, tal como o homem, que necessita de tratamento |
| WO2005118561A1 (en) * | 2004-05-27 | 2005-12-15 | Ucb, S.A. | Benzoxazolone derivatives, processes for preparing them and their uses |
| MY148644A (en) | 2005-07-18 | 2013-05-15 | Orion Corp | New pharmaceutical compounds |
| WO2007099828A1 (ja) | 2006-02-23 | 2007-09-07 | Shionogi & Co., Ltd. | 環式基で置換された含窒素複素環誘導体 |
| JPWO2009025265A1 (ja) * | 2007-08-21 | 2010-11-25 | 塩野義製薬株式会社 | ピペラジン誘導体 |
| US8420670B2 (en) * | 2007-08-22 | 2013-04-16 | Abbott Laboratories | 4-benzylaminoquinolines, pharmaceutical compositions containing them, and their use in therapy |
| CN102083797B (zh) * | 2008-04-01 | 2014-06-04 | Abbvie公司 | 四氢异喹啉、含有它们的药物组合物和它们在治疗中的用途 |
| JP2012500801A (ja) * | 2008-08-21 | 2012-01-12 | リヒター ゲデオン ニルバーノシャン ミーケデーレスベニュタールシャシャーグ | Cns疾患の治療法 |
| AR075442A1 (es) | 2009-02-16 | 2011-03-30 | Abbott Gmbh & Co Kg | Derivados de aminotetralina, composiciones farmaceuticas que las contienen y sus usos en terapia |
| TW201038569A (en) | 2009-02-16 | 2010-11-01 | Abbott Gmbh & Co Kg | Heterocyclic compounds, pharmaceutical compositions containing them, and their use in therapy |
| JP5767205B2 (ja) * | 2009-04-02 | 2015-08-19 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung | オートタキシン阻害剤としての複素環式化合物 |
| US8877794B2 (en) | 2010-08-13 | 2014-11-04 | Abbott Laboratories | Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US9051280B2 (en) | 2010-08-13 | 2015-06-09 | AbbVie Deutschland GmbH & Co. KG | Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US8883839B2 (en) | 2010-08-13 | 2014-11-11 | Abbott Laboratories | Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US9045459B2 (en) | 2010-08-13 | 2015-06-02 | AbbVie Deutschland GmbH & Co. KG | Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US8846743B2 (en) | 2010-08-13 | 2014-09-30 | Abbott Laboratories | Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US9309200B2 (en) | 2011-05-12 | 2016-04-12 | AbbVie Deutschland GmbH & Co. KG | Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy |
| MX2014001457A (es) | 2011-08-05 | 2014-08-21 | Abbvie Deutschland | Derivados de aminocromano, de aminotiocromano y de amino-1,2,3,4-tetrahidroquinolina composiciones farmaceuticas que los contienen, y su uso en terapia. |
| CN104011028A (zh) | 2011-11-18 | 2014-08-27 | 艾伯维德国有限责任两合公司 | N-取代的氨基苯并环庚烯、氨基四氢化萘、氨基茚满和苯烷基胺衍生物、包含所述衍生物的药物组合物及其在治疗中的用途 |
| US9365512B2 (en) | 2012-02-13 | 2016-06-14 | AbbVie Deutschland GmbH & Co. KG | Isoindoline derivatives, pharmaceutical compositions containing them, and their use in therapy |
| JP6125619B2 (ja) * | 2012-05-21 | 2017-05-10 | ドクトア・アウグスト・ボルフ・ゲーエムベーハー・ウント・コンパニー・カー・ゲー−アルツナイミツテル | 新規な1,3−ベンゾオキサゾール−2(3h)−オンならびに医薬品および化粧品としてのこれらの使用 |
| US9650334B2 (en) | 2013-03-15 | 2017-05-16 | Abbvie Inc. | Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US9656955B2 (en) | 2013-03-15 | 2017-05-23 | Abbvie Inc. | Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy |
| KR102237887B1 (ko) | 2013-03-15 | 2021-04-07 | 멜린타 서브시디어리 코프. | 항생제를 사용하여 과체중 및 비만 환자에서 감염을 치료하는 방법 |
| CN104211635A (zh) * | 2013-06-03 | 2014-12-17 | 中国科学院上海药物研究所 | 一类哌啶类化合物及其制备方法、药物组合物和用途 |
| AU2014336154A1 (en) | 2013-10-17 | 2016-04-28 | AbbVie Deutschland GmbH & Co. KG | Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy |
| AU2014336153A1 (en) | 2013-10-17 | 2016-04-28 | AbbVie Deutschland GmbH & Co. KG | Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US9550754B2 (en) | 2014-09-11 | 2017-01-24 | AbbVie Deutschland GmbH & Co. KG | 4,5-dihydropyrazole derivatives, pharmaceutical compositions containing them, and their use in therapy |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH17194A (en) * | 1980-03-06 | 1984-06-19 | Otsuka Pharma Co Ltd | Novel carbostyril derivatives,and pharmaceutical composition containing the same |
| DK288287A (da) * | 1986-06-09 | 1987-12-10 | Pfizer | Heterocycliske forbindelser samt farmaceutiske praeparater til behandling af allergiske eller inflammatoriske tilstande |
| US5036088A (en) * | 1986-06-09 | 1991-07-30 | Pfizer Inc. | Antiallergy and antiinflammatory agents, compositions and use |
| JPH0283376A (ja) | 1988-09-19 | 1990-03-23 | Pfizer Pharmaceut Co Ltd | ベンゾオキサゾロン誘導体および抗アレルギー又は抗炎症組成物 |
| IL93473A0 (en) | 1989-02-28 | 1990-11-29 | Pfizer | Antiinflammatory benzoxazolones |
| ATE174915T1 (de) | 1994-10-31 | 1999-01-15 | Merck Patent Gmbh | Benzylpiperidinderivate mit hoher affinität zu bindungsstellen von aminosäure-rezeptoren |
| US6794402B2 (en) * | 2000-05-31 | 2004-09-21 | Warner-Lambert Company | Bicyclic cyclohexylamines and their use as NMDA receptor antagonists |
| MXPA02010503A (es) | 2000-06-06 | 2003-03-10 | Warner Lambert Co | Ciclohexilaminas biciclicas y su uso como antagonistas del receptor nmda. |
| HRP20040178B1 (hr) * | 2001-07-24 | 2013-05-31 | Richter Gedeon Vegyészeti Gyár RT | Derivati piperidina kao antagonisti nmda receptora |
-
2002
- 2002-03-12 DE DE10210779A patent/DE10210779A1/de not_active Withdrawn
-
2003
- 2003-03-05 US US10/507,581 patent/US7816376B2/en not_active Expired - Fee Related
- 2003-03-05 WO PCT/EP2003/002224 patent/WO2003076420A1/de not_active Ceased
- 2003-03-05 CN CNA038057905A patent/CN1642927A/zh active Pending
- 2003-03-05 AT AT03708178T patent/ATE410418T1/de not_active IP Right Cessation
- 2003-03-05 CA CA002478945A patent/CA2478945A1/en not_active Abandoned
- 2003-03-05 DK DK03708178T patent/DK1485363T3/da active
- 2003-03-05 EP EP03708178A patent/EP1485363B1/de not_active Expired - Lifetime
- 2003-03-05 DE DE50310609T patent/DE50310609D1/de not_active Expired - Lifetime
- 2003-03-05 ES ES03708178T patent/ES2315483T3/es not_active Expired - Lifetime
- 2003-03-05 AU AU2003212305A patent/AU2003212305B2/en not_active Ceased
- 2003-03-05 SI SI200331440T patent/SI1485363T1/sl unknown
- 2003-03-05 JP JP2003574639A patent/JP2005519953A/ja active Pending
- 2003-03-05 RU RU2004130426/04A patent/RU2004130426A/ru not_active Application Discontinuation
- 2003-03-05 PL PL03371215A patent/PL371215A1/xx unknown
- 2003-03-05 PT PT03708178T patent/PT1485363E/pt unknown
-
2008
- 2008-12-30 CY CY20081101501T patent/CY1108674T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003076420A1 (de) | 2003-09-18 |
| US7816376B2 (en) | 2010-10-19 |
| EP1485363B1 (de) | 2008-10-08 |
| EP1485363A1 (de) | 2004-12-15 |
| CN1642927A (zh) | 2005-07-20 |
| CY1108674T1 (el) | 2014-04-09 |
| JP2005519953A (ja) | 2005-07-07 |
| ES2315483T3 (es) | 2009-04-01 |
| ATE410418T1 (de) | 2008-10-15 |
| DE50310609D1 (de) | 2008-11-20 |
| DE10210779A1 (de) | 2003-10-09 |
| AU2003212305B2 (en) | 2009-04-23 |
| AU2003212305A1 (en) | 2003-09-22 |
| US20050124627A1 (en) | 2005-06-09 |
| CA2478945A1 (en) | 2003-09-18 |
| PT1485363E (pt) | 2009-01-09 |
| RU2004130426A (ru) | 2005-05-27 |
| PL371215A1 (en) | 2005-06-13 |
| SI1485363T1 (sl) | 2009-02-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1108674T1 (el) | Κυκλικα αμιδια | |
| AU2003224064A8 (en) | Substituted indoles | |
| MX2009011830A (es) | Compuestos amino-heterociclicos. | |
| TW200738666A (en) | Benzenesulfonyl-chromane, thiochromane, tetrahydronaphthalene and related gamma secretase inhibitors | |
| MXPA06002296A (es) | Tienopiridina-fenilacetamidas y sus derivados utiles como nuevos agentes antiangiogenicos. | |
| ATE463495T1 (de) | Oxadiazolylpyrazolopyrimidine als mglur2- antagonisten | |
| NO20064726L (no) | Imidazolforbindelser for behandling av neurodegenerative forstyrrelser | |
| MY147390A (en) | Substituted isoindoles as bace inhibitors and their use | |
| SE0303180D0 (sv) | Novel compounds | |
| EA200500342A1 (ru) | Гетероциклические замещённые пиперазины для лечения шизофрении | |
| SE0302232D0 (sv) | Novel Compounds | |
| DE602004028150D1 (de) | Aminopyrazolderivate als gsk-3-inhibitoren | |
| NO20063275L (no) | Anvendelse av substituerte 2-aminotetraliner for forebyggende behandling av Parkinsons sykdom | |
| ATE544744T1 (de) | Verfahren zur herstellung von benzoesaure derivaten | |
| MY149422A (en) | 5-(arylsulfonyl)-pyrazolopiperidines | |
| NO20004668L (no) | 1-(3-heteroarylpropyl- eller -prop-2-enyl)-4- benzylpiperidiner anvendt som NMDA-reseptorantagonister | |
| TW200510378A (en) | N-substituted nonaryl-heterocyclic nmda/nr2b antagonists | |
| UY27825A1 (es) | Derivados de n-acilamino bencil eter | |
| MXPA04005313A (es) | Derivados de aminotetralin como antagonistas del receptor muscarinico. | |
| MXPA06000416A (es) | Amidas azaheterociclicas novedosas utiles para tratar el dolor. | |
| TW200602297A (en) | Sulfonamide compounds for the treatment of neurodegenerative disorders | |
| SV2005001840A (es) | Compuestos de oxazol para el tratamiento de trastornos neurodegenerativos - docket 17005 | |
| IL184439A0 (en) | 2,5-disubstituted phenyl methanone derivatives as glycine transporter 1 | |
| MX2009005242A (es) | Derivados de 3-(hetero)arilisoquinolinamida sustituida en posición 5, 6 o 7 y uso terapeutico del mismo. | |
| ATE524171T1 (de) | Verwendung von 2-(2-nitro-4- trifluormethylbenzoyl)-1,3-cyclohexandion bei der behandlung der parkinson-krankheit |