[go: up one dir, main page]

DK1476196T3 - Oral formulering af fast oplösning for et aktive stof, der er tungtoplöseligt i vand - Google Patents

Oral formulering af fast oplösning for et aktive stof, der er tungtoplöseligt i vand

Info

Publication number
DK1476196T3
DK1476196T3 DK03706620T DK03706620T DK1476196T3 DK 1476196 T3 DK1476196 T3 DK 1476196T3 DK 03706620 T DK03706620 T DK 03706620T DK 03706620 T DK03706620 T DK 03706620T DK 1476196 T3 DK1476196 T3 DK 1476196T3
Authority
DK
Denmark
Prior art keywords
water
active substance
solid solution
oral solid
soluble active
Prior art date
Application number
DK03706620T
Other languages
English (en)
Inventor
Henricus R M Gorissen
Original Assignee
Solvay Pharm Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Bv filed Critical Solvay Pharm Bv
Application granted granted Critical
Publication of DK1476196T3 publication Critical patent/DK1476196T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK03706620T 2002-02-14 2003-02-11 Oral formulering af fast oplösning for et aktive stof, der er tungtoplöseligt i vand DK1476196T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02075623 2002-02-14
PCT/EP2003/050014 WO2003068266A1 (en) 2002-02-14 2003-02-11 Oral solid solution formulation of a poorly water-soluble active substance

Publications (1)

Publication Number Publication Date
DK1476196T3 true DK1476196T3 (da) 2007-03-05

Family

ID=27619166

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03706620T DK1476196T3 (da) 2002-02-14 2003-02-11 Oral formulering af fast oplösning for et aktive stof, der er tungtoplöseligt i vand

Country Status (24)

Country Link
US (2) US20050008697A1 (da)
EP (1) EP1476196B1 (da)
JP (1) JP2005517041A (da)
KR (1) KR101014545B1 (da)
CN (1) CN1273194C (da)
AR (1) AR038681A1 (da)
AT (1) ATE345817T1 (da)
AU (1) AU2003208713B2 (da)
BR (1) BR0307278A (da)
CA (1) CA2472744A1 (da)
DE (1) DE60309839T2 (da)
DK (1) DK1476196T3 (da)
ES (1) ES2277635T3 (da)
HR (1) HRP20040613A2 (da)
IL (2) IL162883A0 (da)
MX (1) MXPA04007852A (da)
NO (1) NO20043832L (da)
PL (1) PL370452A1 (da)
PT (1) PT1476196E (da)
RU (1) RU2314811C2 (da)
SI (1) SI1476196T1 (da)
UA (1) UA79267C2 (da)
WO (1) WO2003068266A1 (da)
ZA (1) ZA200405608B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004062692A1 (en) * 2003-01-13 2004-07-29 Solvay Pharmaceuticals B.V. Formulation of poorly water-soluble active substances
US8377952B2 (en) * 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US20050267124A1 (en) * 2004-05-14 2005-12-01 Solvay Pharmaceuticals Gmbh Pharmaceutical compositions comprising NEP-inhibitors, inhibitors of the endogenous producing system and PDEV inhibiitors
TW200633713A (en) * 2004-12-23 2006-10-01 Solvay Pharm Bv Oral immediate release formulation of a poorly water-soluble active substance
US20060159748A1 (en) * 2004-12-23 2006-07-20 Rajesh Jain Oral immediate release formulation of a poorly water-soluble active substance
WO2007054975A1 (en) * 2005-11-08 2007-05-18 Panacea Biotec Ltd Pharmaceutical compositions for the treatment of cardiovascular and other associated disorders
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
JP2007308479A (ja) 2006-04-20 2007-11-29 Shin Etsu Chem Co Ltd 固体分散体製剤
KR20090032085A (ko) * 2006-06-16 2009-03-31 솔베이 파마슈티칼스 비. 브이 수용성이 불량한 활성 물질의 경구 투여용 약제학적 조성물
WO2007147873A1 (en) * 2006-06-22 2007-12-27 Solvay Pharmaceuticals B.V. Oral pharmaceutical composition of a poorly water-soluble active substance
WO2008003769A2 (en) * 2006-07-06 2008-01-10 Ares Trading S.A. An oral pharmaceutical composition of an anilinopyrimidine, its preparation and use thereof
US20080181959A1 (en) * 2006-09-01 2008-07-31 Ilan Zalit Solid composites of a calcium receptor-active compound
AR071375A1 (es) * 2008-04-22 2010-06-16 Solvay Pharm Gmbh Formulaciones para ingredientes farmaceuticos activos de permeabilidad deficiente, proceso de preparacion y producto
WO2010144865A2 (en) 2009-06-12 2010-12-16 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
LT2600839T (lt) * 2010-08-04 2018-03-26 GrĆ¼nenthal GmbH Vaistinė dozavimo forma, apimanti 6'-fluor-(n-metil- arba n,n-dimetil-)-4-fenil-4',9'-dihidro-3'h-spiro[cikloheksan-1,1'-pirano[3,4,b]indol]-4-aminą
AU2011287955B2 (en) 2010-08-04 2015-07-09 Grünenthal GmbH Pharmaceutical dosage form comprising 6'-fluoro-(N-methyl- or N,N-dimethyl-)-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine for the treatment of neuropathic pain
US20180185399A1 (en) * 2015-07-03 2018-07-05 Zhejiang Hisun Pharmaceutical Co., Ltd. Ginsenoside c-k oral solid preparation and preparation method thereof
PL424453A1 (pl) 2018-01-31 2019-08-12 Forty-Four Pharmaceuticals Spółka Z Ograniczoną Odpowiedzialnością Sposoby zmniejszania szkodliwego działania niedoboru perfuzji narządów miąższowych przez inhibitory obojętnej endopeptydazy (NEP) i ludzkiej rozpuszczalnej endopeptydazy (hSEP)
PL424452A1 (pl) 2018-01-31 2019-08-12 Forty-Four Pharmaceuticals Spółka Z Ograniczoną Odpowiedzialnością Inhibitory obojętnej endopeptydazy (NEP) i ludzkiej rozpuszczalnej endopeptydazy (hSEP) do profilaktyki i leczenia chorób oczu
PL3886820T3 (pl) * 2018-11-30 2023-08-14 Chemocentryx, Inc. Postacie użytkowe będące kapsułkami
WO2025018777A1 (ko) * 2023-07-18 2025-01-23 삼아제약 주식회사 프란루카스트 함유 약제학적 조성물의 제조방법 및 상기 제조방법에 의해 제조된 약제학적 조성물

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3359167A (en) * 1965-07-22 1967-12-19 Pfizer & Co C Vitamin a compositions
CU35543A1 (es) * 1980-10-09 1983-05-05 Hoffmann La Roche Prostaglandines
NZ224497A (en) * 1987-05-18 1990-04-26 Janssen Pharmaceutica Nv Pharmaceutical composition comprising flunarizine
US5281420A (en) * 1992-05-19 1994-01-25 The Procter & Gamble Company Solid dispersion compositions of tebufelone
DE19510566A1 (de) * 1995-03-23 1996-09-26 Kali Chemie Pharma Gmbh Benzazepin-, Benzoxazepin- und Benzothiazepin-N-essigsäurederivate sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE19638020A1 (de) * 1996-09-18 1998-03-19 Solvay Pharm Gmbh Die gastrointestinale Durchblutung fördernde Arzneimittel
ZA9710927B (en) * 1996-12-06 1998-06-15 Fujisawa Pharmaceutical Co Pharmaceutical composition.
ATE275963T1 (de) * 1997-01-30 2004-10-15 Novartis Pharma Gmbh Ölfreie pharmazeutische zusammensetzung welche cyclosporin enthält
US6008191A (en) * 1997-09-08 1999-12-28 Panacea Biotec Limited Pharmaceutical compositions containing cyclosporin
KR100336090B1 (ko) * 1998-06-27 2002-05-27 윤승원 오일, 지방산 또는 이들의 혼합물을 함유한 난용성 약물의 고형분산제제
DE19906310A1 (de) * 1999-02-16 2000-08-17 Solvay Pharm Gmbh Arzneimittel zur Behandlung von Bluthochdruck
DE19932555A1 (de) * 1999-07-13 2001-01-18 Solvay Pharm Gmbh Arzneimittel mit protektiver Wirkung gegen oxidativ-toxische und insbesondere gegen kardiotoxische Substanzen
US20010036959A1 (en) * 2000-04-03 2001-11-01 Gabel Rolf Dieter Carvedilol-hydrophilic solutions

Also Published As

Publication number Publication date
RU2004127457A (ru) 2005-04-20
EP1476196B1 (en) 2006-11-22
RU2314811C2 (ru) 2008-01-20
SI1476196T1 (sl) 2007-04-30
DE60309839T2 (de) 2007-03-15
US20110086844A1 (en) 2011-04-14
CN1273194C (zh) 2006-09-06
ZA200405608B (en) 2005-06-24
DE60309839D1 (de) 2007-01-04
IL162883A (en) 2009-05-04
JP2005517041A (ja) 2005-06-09
KR101014545B1 (ko) 2011-02-16
AR038681A1 (es) 2005-01-26
NO20043832L (no) 2004-09-13
BR0307278A (pt) 2004-12-28
PT1476196E (pt) 2007-02-28
AU2003208713A1 (en) 2003-09-04
HK1077218A1 (en) 2006-02-10
ATE345817T1 (de) 2006-12-15
CN1633307A (zh) 2005-06-29
AU2003208713B9 (en) 2003-09-04
MXPA04007852A (es) 2004-10-15
IL162883A0 (en) 2005-11-20
WO2003068266A1 (en) 2003-08-21
HRP20040613A2 (en) 2005-04-30
EP1476196A1 (en) 2004-11-17
ES2277635T3 (es) 2007-07-16
UA79267C2 (en) 2007-06-11
PL370452A1 (en) 2005-05-30
KR20040085193A (ko) 2004-10-07
AU2003208713B2 (en) 2007-10-18
US20050008697A1 (en) 2005-01-13
CA2472744A1 (en) 2003-08-21

Similar Documents

Publication Publication Date Title
DK1476196T3 (da) Oral formulering af fast oplösning for et aktive stof, der er tungtoplöseligt i vand
IS7192A (is) Munntökuform af própívíríni, þannig útbúið að hinum virka þætti efnisins er sleppt á löngum tíma
DK1480679T3 (da) Farmaceutisk formulering af iressa, der omfatter et vandoplöseligt cellulosederivat
DK1501787T3 (da) N-biphenylmethylaminocycloalkancarboxamid-derivater med en substituerent på methyl, der er nyttige som bradykininantagonister
DK1615646T4 (da) Farmaceutiske formuleringer, der indeholder methylnaltrexon
DK1235825T3 (da) Nye benzoimidazolderivater, der er anvendelige som antiproliferative midler
DK1776010T3 (da) Fremgangsmåde til fremstilling af vandige aktivstofsammensætninger af aktivstoffer, som er tungt oplöselige i vand
DK1551511T5 (da) Heterocykliske aromatiske forbindelser, der er anvendelige som væksthormonsekretagoger
DK1541332T3 (da) Maskine til fremstilling af poser
DE60234409D1 (de) Säuregenerator, Sulfonsäure, Sulfonsäurederivate und strahlungsempfindliche Zusammensetzung
DE60322920D1 (de) Heterocyclische verbindungen mit hiv-integrase-hemmender wirkung
DK1689360T3 (da) Tørpulverformuleringer
DE60316323D1 (de) Feste pharmazeutische formulierungen mit telmisartan
NO20043998L (no) Oral administreringsform for tungtloselige basiske aktive virkestoffer
DE60317967D1 (de) Umhüllte feste Darreichungsform
DK1492785T3 (da) 2-hydroxy-3-heteroarylindol-derivater som GSK3-inhibitorer
DK1317181T3 (da) Fremgangsmåde til fremstilling af en herbicid faststofformulering
NO20032503L (no) Fenyletenyl- eller fenyletynylderivater som glutamatreseptorantagonister
DK1536783T3 (da) Faste formuleringer, der omfatter en indolinonforbindelse
IS7571A (is) Ný lífeðlisfræðilega virk efni
NO20052884D0 (no) Substituerte indolpyridinforbindelser som anti-infeksjonsmidler.
NO20032142L (no) Substituerte 2-fenylaminoimidazolin-fenylketon-derivater som IP-antagonister
DK1611884T3 (da) Plaster, indeholdende diclofenac
IS7500A (is) thurrdufts samsetningar
DK1494650T3 (da) Farmaceutisk formulering, der indeholder melatonin