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DK1458888T3 - Fremgangsmåder til behandling af psykose og skizofreni baseret på polymorfier i CNTF-genet - Google Patents

Fremgangsmåder til behandling af psykose og skizofreni baseret på polymorfier i CNTF-genet

Info

Publication number
DK1458888T3
DK1458888T3 DK02791794.7T DK02791794T DK1458888T3 DK 1458888 T3 DK1458888 T3 DK 1458888T3 DK 02791794 T DK02791794 T DK 02791794T DK 1458888 T3 DK1458888 T3 DK 1458888T3
Authority
DK
Denmark
Prior art keywords
psychosis
polymorphisms
treatment
methods
cntf gene
Prior art date
Application number
DK02791794.7T
Other languages
English (en)
Inventor
Mihael Hristos Polymeropoulos
Sridhar Kudaravalli
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK1458888T3 publication Critical patent/DK1458888T3/da

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475Assays involving growth factors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/30Psychoses; Psychiatry
    • G01N2800/302Schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Neurology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK02791794.7T 2001-12-10 2002-12-09 Fremgangsmåder til behandling af psykose og skizofreni baseret på polymorfier i CNTF-genet DK1458888T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33983501P 2001-12-10 2001-12-10
PCT/EP2002/013937 WO2003054226A2 (en) 2001-12-10 2002-12-09 Methods of treating psychosis and schizophrenia based on a polymorphism in the ctf gene

Publications (1)

Publication Number Publication Date
DK1458888T3 true DK1458888T3 (da) 2011-06-20

Family

ID=23330814

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02791794.7T DK1458888T3 (da) 2001-12-10 2002-12-09 Fremgangsmåder til behandling af psykose og skizofreni baseret på polymorfier i CNTF-genet

Country Status (15)

Country Link
US (3) US20050059006A1 (da)
EP (1) EP1458888B1 (da)
JP (2) JP2005512576A (da)
CN (1) CN1612941B (da)
AT (1) ATE503845T1 (da)
AU (1) AU2002358110A1 (da)
BR (1) BRPI0214821B8 (da)
CA (1) CA2468972A1 (da)
CY (1) CY1111594T1 (da)
DE (1) DE60239634D1 (da)
DK (1) DK1458888T3 (da)
ES (1) ES2364037T3 (da)
PT (1) PT1458888E (da)
SI (1) SI1458888T1 (da)
WO (1) WO2003054226A2 (da)

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US8652776B2 (en) * 2007-09-10 2014-02-18 Vanda Pharmaceuticals, Inc. Prediction of QT prolongation based on SNP genotype
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US8729100B2 (en) 2007-12-13 2014-05-20 Vanda Pharmaceuticals, Inc. Method and composition for treating an alpha adrenoceptor-mediated condition
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US9057104B2 (en) 2009-05-15 2015-06-16 Vanda Pharmaceuticals, Inc. Antipsychotic treatment based on DRD2 or ANKK1 SNP genotype
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US11214827B2 (en) 2018-08-30 2022-01-04 Vanda Pharmaceuticals Inc. Genetic markers for enhancing efficacy of antipsychotic treatment with iloperidone
JP2022530390A (ja) * 2019-04-24 2022-06-29 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 抗精神病剤の応答を予測するための方法
CN110184345B (zh) * 2019-07-11 2020-05-05 南京先声医学检验有限公司 用于检测精神及神经类疾病用药相关snp位点的引物组、应用、产品及方法
CN111187829A (zh) * 2020-02-24 2020-05-22 内蒙古医科大学 Lp基因启动子区甲基化检测引物与检测方法及其应用

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Also Published As

Publication number Publication date
ATE503845T1 (de) 2011-04-15
BR0214821A (pt) 2004-11-03
EP1458888A2 (en) 2004-09-22
AU2002358110A8 (en) 2003-07-09
WO2003054226A3 (en) 2004-04-01
WO2003054226A2 (en) 2003-07-03
JP2011006422A (ja) 2011-01-13
HK1069413A1 (en) 2005-05-20
DE60239634D1 (de) 2011-05-12
US20080027106A1 (en) 2008-01-31
BRPI0214821B1 (pt) 2015-07-07
BRPI0214821B8 (pt) 2021-07-27
ES2364037T3 (es) 2011-08-23
CN1612941B (zh) 2011-11-16
SI1458888T1 (sl) 2011-07-29
CA2468972A1 (en) 2003-07-03
JP2005512576A (ja) 2005-05-12
US20090239908A1 (en) 2009-09-24
CN1612941A (zh) 2005-05-04
AU2002358110A1 (en) 2003-07-09
PT1458888E (pt) 2011-06-01
JP5785697B2 (ja) 2015-09-30
US20050059006A1 (en) 2005-03-17
EP1458888B1 (en) 2011-03-30
US8460867B2 (en) 2013-06-11
CY1111594T1 (el) 2015-10-07

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