DK1458447T3 - Kombination af cytokrom-p450-beroende proteasinhibitorer - Google Patents

Kombination af cytokrom-p450-beroende proteasinhibitorer

Info

Publication number: DK1458447T3
Authority: DK; Denmark
Prior art keywords: cytochrome; combination; protease inhibitors; dependent protease; dependent
Prior art date: 2001-12-12

Application number

DK02793018.9T

Other languages

English (en)

Inventor

Der Geest Ronald Van

Paul Stoffels

Cornelis Groen

Dirk Edward Desire Jochmans

Original Assignee

Tibotec Pharm Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-12-12

Filing date

2002-12-12

Publication date

2010-01-18

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8181408&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1458447(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2002-12-12 Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd

2010-01-18 Application granted granted Critical

2010-01-18 Publication of DK1458447T3 publication Critical patent/DK1458447T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Virology (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Ultra Sonic Daignosis Equipment (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

DK02793018.9T 2001-12-12 2002-12-12 Kombination af cytokrom-p450-beroende proteasinhibitorer DK1458447T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01204841		2001-12-12
PCT/EP2002/014277 WO2003049746A2 (en)	2001-12-12	2002-12-12	Combination of cytochome p450 dependent protease inhibitors

Publications (1)

Publication Number	Publication Date
DK1458447T3 true DK1458447T3 (da)	2010-01-18

Family

ID=8181408

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02793018.9T DK1458447T3 (da)	2001-12-12	2002-12-12	Kombination af cytokrom-p450-beroende proteasinhibitorer

Country Status (27)

Country	Link
US (1)	US20050119338A1 (da)
EP (1)	EP1458447B1 (da)
JP (1)	JP2005511723A (da)
KR (1)	KR100974921B1 (da)
CN (1)	CN100335060C (da)
AR (1)	AR037797A1 (da)
AT (1)	ATE442189T1 (da)
AU (1)	AU2002358713B2 (da)
BR (1)	BR0215043A (da)
CA (1)	CA2469343C (da)
CY (1)	CY1110604T1 (da)
DE (1)	DE60233677D1 (da)
DK (1)	DK1458447T3 (da)
ES (1)	ES2333206T3 (da)
HR (1)	HRP20040619A2 (da)
HU (1)	HUP0402644A3 (da)
IL (1)	IL162353A0 (da)
MX (1)	MXPA04005755A (da)
NO (1)	NO20042666L (da)
NZ (1)	NZ533826A (da)
PL (1)	PL373072A1 (da)
PT (1)	PT1458447E (da)
RU (1)	RU2329050C2 (da)
SI (1)	SI1458447T1 (da)
TW (1)	TWI286476B (da)
WO (1)	WO2003049746A2 (da)
ZA (1)	ZA200404633B (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL1670773T3 (pl) *	2003-09-30	2007-06-29	Tibotec Pharm Ltd	Sposób wytwarzania sulfonamidów benzoksazolu i ich związków pośrednich
WO2005063209A1 (en) *	2003-12-23	2005-07-14	Tibotec Pharmaceuticals Ltd.	Self-microemulsifying drug delivery systems of a hiv protease inhibitor
MXPA06012909A (es) *	2004-05-07	2007-09-06	Sequoia Pharmaceuticals Inc	Inhibidores de proteasa retroviral repelente de resistencia.
EP1765337B1 (en) *	2004-07-08	2008-08-27	Tibotec Pharmaceuticals Ltd.	Combination of tenofovir, ritonavir and tmc114
RU2421459C2 (ru)	2005-02-25	2011-06-20	Тиботек Фармасьютикалз Лтд.	Синтез предшественника ингибитора протеазы
EP1865967A4 (en) *	2005-04-08	2011-02-09	Chimerix Inc	COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTIONS AND OTHER DISEASES
AR053845A1 (es)	2005-04-15	2007-05-23	Tibotec Pharm Ltd	5-tiazolilmetil[(1s,2r)-3-[[(2-amino-6-benzoxazolil)sulfonil)](2-metilpropil)amino]-2-hidroxi-1-(fenilmetil)propil]carbamato como mejorador de farmacos metabolizados por el citocromo p450
AR058238A1 (es)	2005-11-28	2008-01-23	Tibotec Pharm Ltd	Compuestos y derivados de aminofenilsulfonamida sustituida como inhibidores de proteasa del vih
TWI385173B (zh)	2005-11-28	2013-02-11	Tibotec Pharm Ltd	作為ｈｉｖ蛋白酶抑制劑之經取代的胺基苯基磺醯胺化合物
KR101524165B1 (ko) *	2005-12-30	2015-06-01	길리애드 사이언시즈, 인코포레이티드	Ｈｉｖ 인테그라제 억제제의 약동학을 개선하기 위한 방법
JO2841B1 (en) *	2006-06-23	2014-09-15	تيبوتيك فارماسيوتيكالز ليمتد	2-(substituted-amino) -benzothiazole sulfonamide as protease inhibitors HIV (HIV)
AU2007285759B2 (en) *	2006-08-18	2013-11-21	Sequoia Pharmaceuticals, Inc.	Compositions and methods for inhibiting cytochrome P450
CA2681718A1 (en) *	2007-03-23	2008-10-02	University Of Massachusetts	Hiv-1 protease inhibitors
UA103013C2 (uk)	2007-12-06	2013-09-10	Тиботек Фармасьютикелз	Амідні сполуки як активатори противірусних препаратів
GT200800303A (es) *	2007-12-24	2009-09-18		Combinacion anti-retroviral
CN101977610B (zh)	2008-01-25	2012-05-16	奇默里克斯公司	治疗病毒感染的方法
EA026673B1 (ru)	2008-10-07	2017-05-31	Янссен Сайенсиз Айрлэнд Юси	Амидные соединения в качестве усилителей противовирусных препаратов
WO2010132494A1 (en) *	2009-05-11	2010-11-18	Ghosh Arun K	Compounds and methods for treating aids and hiv infections
JO3090B1 (ar) *	2009-12-11	2017-03-15	Janssen Sciences Ireland Uc	5- امينو-4- هيدروكسي-بنتويل اميدات
DK2534150T3 (da)	2010-02-12	2017-06-12	Chimerix Inc	Fremgangsmåder til behandling af virusinfektion
WO2011139709A2 (en)	2010-04-26	2011-11-10	Chimerix, Inc.	Methods of treating retroviral infections and related dosage regimes
AU2011261586B2 (en) *	2010-06-01	2015-08-27	Angion Biomedica Corp.	Cytochrome P450 inhibitors and uses thereof
US20140142070A1 (en)	2011-07-07	2014-05-22	Janssen R&D Ireland	Darunavir combination formulations
PL2729128T3 (pl)	2011-07-07	2017-05-31	Janssen Sciences Ireland Uc	Preparat darunawiru

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1995010281A1 (en) *	1993-10-13	1995-04-20	Merck & Co., Inc.	Combination therapy for hiv infection
US6037157A (en) *	1995-06-29	2000-03-14	Abbott Laboratories	Method for improving pharmacokinetics
ES2262184T3 (es) *	1996-08-05	2006-11-16	Myriad Genetics, Inc.	Utilizacion de mimeticos de hojas beta como inhibidores de proteasa y de kinasa o como inhibidores de factores de transcripcion.
US6180634B1 (en) *	1997-11-13	2001-01-30	Merck & Co., Inc.	Combination therapy for the treatment of AIDS
US6436989B1 (en) *	1997-12-24	2002-08-20	Vertex Pharmaceuticals, Incorporated	Prodrugs of aspartyl protease inhibitors
WO1999067254A2 (en) *	1998-06-23	1999-12-29	The United States Of America Represented By The Secretary, Department Of Health And Human Services	Multi-drug resistant retroviral protease inhibitors and use thereof
ES2362404T5 (es) *	1998-06-23	2015-11-25	The United States Of America, Represented By The Secretary, Department Of Health And Human Services	Ensayo de aptitud y métodos para reducir la resistencia del VIH a terapia
MY121765A (en) *	1998-07-20	2006-02-28	Abbott Lab	Polymorph of ritonavir
TWI260322B (en) *	1999-02-12	2006-08-21	Vertex Pharma	Inhibitors of aspartyl protease
WO2000047551A2 (en) *	1999-02-12	2000-08-17	Vertex Pharmaceuticals Incorporated	Inhibitors of aspartyl protease

2002
- 2002-12-11 TW TW091135882A patent/TWI286476B/zh not_active IP Right Cessation
- 2002-12-11 AR ARP020104805A patent/AR037797A1/es unknown
- 2002-12-12 ES ES02793018T patent/ES2333206T3/es not_active Expired - Lifetime
- 2002-12-12 PL PL02373072A patent/PL373072A1/xx not_active IP Right Cessation
- 2002-12-12 HU HU0402644A patent/HUP0402644A3/hu unknown
- 2002-12-12 HR HR20040619A patent/HRP20040619A2/hr not_active Application Discontinuation
- 2002-12-12 WO PCT/EP2002/014277 patent/WO2003049746A2/en not_active Ceased
- 2002-12-12 NZ NZ533826A patent/NZ533826A/en not_active IP Right Cessation
- 2002-12-12 RU RU2004121144/15A patent/RU2329050C2/ru not_active IP Right Cessation
- 2002-12-12 JP JP2003550795A patent/JP2005511723A/ja active Pending
- 2002-12-12 AU AU2002358713A patent/AU2002358713B2/en not_active Revoked
- 2002-12-12 CA CA002469343A patent/CA2469343C/en not_active Expired - Fee Related
- 2002-12-12 EP EP02793018A patent/EP1458447B1/en not_active Revoked
- 2002-12-12 US US10/498,024 patent/US20050119338A1/en not_active Abandoned
- 2002-12-12 PT PT02793018T patent/PT1458447E/pt unknown
- 2002-12-12 BR BR0215043-3A patent/BR0215043A/pt not_active Application Discontinuation
- 2002-12-12 KR KR1020047008830A patent/KR100974921B1/ko not_active Ceased
- 2002-12-12 IL IL16235302A patent/IL162353A0/xx unknown
- 2002-12-12 SI SI200230865T patent/SI1458447T1/sl unknown
- 2002-12-12 DE DE60233677T patent/DE60233677D1/de not_active Expired - Lifetime
- 2002-12-12 AT AT02793018T patent/ATE442189T1/de not_active IP Right Cessation
- 2002-12-12 DK DK02793018.9T patent/DK1458447T3/da active
- 2002-12-12 CN CNB028249119A patent/CN100335060C/zh not_active Expired - Fee Related
2004
- 2004-06-10 ZA ZA200404633A patent/ZA200404633B/en unknown
- 2004-06-14 MX MXPA04005755A patent/MXPA04005755A/es active IP Right Grant
- 2004-06-24 NO NO20042666A patent/NO20042666L/no not_active Application Discontinuation
2009
- 2009-12-09 CY CY20091101283T patent/CY1110604T1/el unknown

Also Published As

Publication number	Publication date
IL162353A0 (en)	2005-11-20
AR037797A1 (es)	2004-12-01
HK1070008A1 (en)	2005-06-10
PL373072A1 (en)	2005-08-08
WO2003049746A3 (en)	2003-12-31
SI1458447T1 (sl)	2010-01-29
BR0215043A (pt)	2004-11-03
HUP0402644A3 (en)	2008-04-28
EP1458447A2 (en)	2004-09-22
DE60233677D1 (de)	2009-10-22
KR20040071182A (ko)	2004-08-11
ES2333206T3 (es)	2010-02-18
CA2469343C (en)	2008-05-13
AU2002358713A1 (en)	2003-06-23
AU2002358713B2 (en)	2009-01-29
EP1458447B1 (en)	2009-09-09
TW200409624A (en)	2004-06-16
ZA200404633B (en)	2005-09-01
JP2005511723A (ja)	2005-04-28
CY1110604T1 (el)	2015-04-29
US20050119338A1 (en)	2005-06-02
CN1604803A (zh)	2005-04-06
NO20042666L (no)	2004-09-09
HRP20040619A2 (en)	2005-08-31
ATE442189T1 (de)	2009-09-15
KR100974921B1 (ko)	2010-08-09
WO2003049746A2 (en)	2003-06-19
HUP0402644A2 (en)	2007-02-28
CA2469343A1 (en)	2003-06-19
CN100335060C (zh)	2007-09-05
RU2329050C2 (ru)	2008-07-20
PT1458447E (pt)	2009-12-16
NZ533826A (en)	2006-04-28
RU2004121144A (ru)	2005-04-20
TWI286476B (en)	2007-09-11
MXPA04005755A (es)	2004-09-10

Publication	Publication Date	Title
DK1458447T3 (da)	2010-01-18	Kombination af cytokrom-p450-beroende proteasinhibitorer
NO20034042D0 (no)	2003-09-12	Metallproteinase-inhibitorer
DE60234125D1 (de)	2009-12-03	E inhibitoren
CY2015028I1 (el)	2016-07-27	Ενας αναστολεας ν-ακυλοσφιγγοσινο γλυκοζυλοτρανσφερασης
EE200300439A (et)	2003-12-15	Metalloproteinaasi inhibiitorid
DK1438306T3 (da)	2014-06-23	Derivater af UK-2A
CY2012007I1 (el)	2014-07-02	Πεπτιδομιμητικοι αναστολεις πρωτεασης
DK1567529T4 (da)	2021-05-10	Pseudopolymorfe former af en hiv-proteaseinhibitor
PT1370553E (pt)	2006-09-29	Inibidores de rhoquinase
ATE286049T1 (de)	2005-01-15	Pyridazinonaldose reductase inhibitoren
NO20034032D0 (no)	2003-09-11	Metallproteinase-inhibitorer
EP1499336A4 (en)	2005-06-01	PROTEASE INHIBITORS
DK1686113T3 (da)	2012-02-20	Inhibitorer af aspartylprotease
FI20010558L (fi)	2002-09-20	Kappaleiden paikannus
DK1451154T3 (da)	2008-05-19	Inhibitorer af cytosolisk phospholipase A2
DK1536796T3 (da)	2008-06-09	N-arylpiperidinsubstituerede biphenylcarboxamider som inhibitorer af apolipoprotein B-sektion
ATE429431T1 (de)	2009-05-15	2-amino-benzoxazol-suphonamide als breitspektrum- hiv-protease-inhibitoren
NO20025786L (no)	2003-02-12	Protaseinhibitorer
NO20025005L (no)	2002-12-06	Proteaseinhibitorer
EP1463521A4 (en)	2009-06-24	INHIBITOR OF GP41
NO20032328D0 (no)	2003-05-22	Proteaseinhibitorer
DK1373898T3 (da)	2006-10-30	Påvisning af inflammationer
SE0100694D0 (sv)	2001-02-28	DHFR inhibitors
DK1319049T3 (da)	2005-03-21	Grunding af stål
DOP2001000307A (es)	2002-11-30	Inhibidores de thrombin