DK1457498T3 - Hidtil ukendt peptid med angiotensinkonvertaseinhibitorisk virkning - Google Patents

Hidtil ukendt peptid med angiotensinkonvertaseinhibitorisk virkning

Info

Publication number: DK1457498T3
Authority: DK; Denmark
Prior art keywords: inhibitory effect; hitherto unknown; unknown peptide; angiotensin convertase; convertase inhibitory
Prior art date: 2001-11-21

Application number

DK02803562T

Other languages

Danish (da)

English (en)

Inventor

Yoshitaka Tamura

Hiroshi Miyakawa

Akio Yamada

Hitoshi Saito

Yasushi Kawaguchi

Hiroshi Ochi

Tomoko Ide

Eri Inoue

Original Assignee

Morinaga Milk Industry Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-11-21

Filing date

2002-11-21

Publication date

2007-06-04

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19167543&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1457498(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2002-11-21 Application filed by Morinaga Milk Industry Co Ltd filed Critical Morinaga Milk Industry Co Ltd

2007-06-04 Application granted granted Critical

2007-06-04 Publication of DK1457498T3 publication Critical patent/DK1457498T3/da

Links

108010064733 Angiotensins Proteins 0.000 title 1
102000015427 Angiotensins Human genes 0.000 title 1
230000002401 inhibitory effect Effects 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1
239000005541 ACE inhibitor Substances 0.000 abstract 1
208000001953 Hypotension Diseases 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
229940044094 angiotensin-converting-enzyme inhibitor Drugs 0.000 abstract 1
239000005018 casein Substances 0.000 abstract 1
BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 abstract 1
235000021240 caseins Nutrition 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
230000007062 hydrolysis Effects 0.000 abstract 1
238000006460 hydrolysis reaction Methods 0.000 abstract 1
208000021822 hypotensive Diseases 0.000 abstract 1
230000001077 hypotensive effect Effects 0.000 abstract 1
108010022588 methionyl-lysyl-proline Proteins 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4732—Casein
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

DK02803562T 2001-11-21 2002-11-21 Hidtil ukendt peptid med angiotensinkonvertaseinhibitorisk virkning DK1457498T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2001355923		2001-11-21
PCT/JP2002/012197 WO2003044044A1 (en)	2001-11-21	2002-11-21	Novel peptide having angiotensin convertase inhibitory effect

Publications (1)

Publication Number	Publication Date
DK1457498T3 true DK1457498T3 (da)	2007-06-04

Family

ID=19167543

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02803562T DK1457498T3 (da)	2001-11-21	2002-11-21	Hidtil ukendt peptid med angiotensinkonvertaseinhibitorisk virkning

Country Status (18)

Country	Link
US (1)	US7022676B2 (no)
EP (1)	EP1457498B9 (no)
JP (1)	JP3816921B2 (no)
KR (1)	KR100615844B1 (no)
CN (1)	CN1240711C (no)
AT (1)	ATE353336T1 (no)
AU (1)	AU2002366037B2 (no)
BR (1)	BR0214299A (no)
CA (1)	CA2468039C (no)
CY (1)	CY1106557T1 (no)
DE (1)	DE60218064T2 (no)
DK (1)	DK1457498T3 (no)
ES (1)	ES2281567T3 (no)
MX (1)	MXPA04004805A (no)
NO (1)	NO328611B1 (no)
NZ (1)	NZ533544A (no)
PT (1)	PT1457498E (no)
WO (1)	WO2003044044A1 (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2004261855B2 (en) *	2003-08-01	2010-09-16	Calpis Co., Ltd.	Casein hydrolyzate, process for producing the same and use thereof
NZ584979A (en) *	2003-12-01	2010-10-29	Meiji Dairies Corp	Peptide inhibiting angiotensin converting enzyme
CN102276690B (zh) *	2011-08-05	2013-03-20	成都中医药大学	降血压功能性多肽及其用途
CN102304169B (zh) *	2011-08-05	2013-03-20	成都中医药大学	降血压多肽及其用途
WO2013125622A1 (ja) *	2012-02-22	2013-08-29	森永乳業株式会社	ジペプチジルペプチダーゼ－ｉｖ阻害剤
JP5832049B2 (ja)	2012-03-09	2015-12-16	森永乳業株式会社	ジペプチジルペプチダーゼ−ｉｖ阻害剤
US9345741B2 (en)	2013-03-15	2016-05-24	Mead Johnson Nutrition Company	Nutritional composition containing a peptide component with adiponectin simulating properties and uses thereof
US9345727B2 (en)	2013-03-15	2016-05-24	Mead Johnson Nutrition Company	Nutritional compositions containing a peptide component and uses thereof
US9138455B2 (en)	2013-03-15	2015-09-22	Mead Johnson Nutrition Company	Activating adiponectin by casein hydrolysate
US9352020B2 (en)	2013-03-15	2016-05-31	Mead Johnson Nutrition Company	Reducing proinflammatory response
US9289461B2 (en)	2013-03-15	2016-03-22	Mead Johnson Nutrition Company	Reducing the risk of autoimmune disease
US8889633B2 (en)	2013-03-15	2014-11-18	Mead Johnson Nutrition Company	Nutritional compositions containing a peptide component with anti-inflammatory properties and uses thereof
JP6344796B2 (ja) *	2014-09-30	2018-06-20	森永乳業株式会社	高齢者用アルツハイマー型認知症改善剤
JP2018057346A (ja) *	2016-10-07	2018-04-12	森永乳業株式会社	カゼイン酵素処理物及びその製造方法
CN107337710A (zh) *	2017-07-26	2017-11-10	盐城卫生职业技术学院	一种抗高血压活性肽The‑The‑Pro及应用和药物组合物
JP7358239B2 (ja) *	2017-09-19	2023-10-10	森永乳業株式会社	エネルギー消費促進用組成物
EP3753569A4 (en)	2018-02-16	2021-12-15	Morinaga Milk Industry Co., Ltd.	COMPOSITION FOR LOWERING BLOOD PRESSURE AND / OR FOR LOWERING NEUTRAL FATS
JP2019142791A (ja) *	2018-02-16	2019-08-29	森永乳業株式会社	血圧降下用及び／又は中性脂肪低減用の組成物
JP6589011B2 (ja) *	2018-05-17	2019-10-09	森永乳業株式会社	脳機能障害改善用経口組成物
CN113321719B (zh) *	2021-05-20	2022-03-18	澳优乳业（中国）有限公司	一种寡肽及其制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH07313185A (ja) *	1992-08-20	1995-12-05	Marino Forum 21	ぺプチドの製造方法
JP3040389B2 (ja) *	1999-01-18	2000-05-15	日本合成化学工業株式会社	ペプチドの製造法

2002
- 2002-11-21 CN CNB028270266A patent/CN1240711C/zh not_active Expired - Lifetime
- 2002-11-21 NZ NZ533544A patent/NZ533544A/en not_active IP Right Cessation
- 2002-11-21 BR BR0214299-6A patent/BR0214299A/pt not_active Application Discontinuation
- 2002-11-21 DK DK02803562T patent/DK1457498T3/da active
- 2002-11-21 WO PCT/JP2002/012197 patent/WO2003044044A1/ja not_active Ceased
- 2002-11-21 CA CA2468039A patent/CA2468039C/en not_active Expired - Lifetime
- 2002-11-21 ES ES02803562T patent/ES2281567T3/es not_active Expired - Lifetime
- 2002-11-21 EP EP02803562A patent/EP1457498B9/en not_active Expired - Lifetime
- 2002-11-21 MX MXPA04004805A patent/MXPA04004805A/es active IP Right Grant
- 2002-11-21 JP JP2003545680A patent/JP3816921B2/ja not_active Expired - Lifetime
- 2002-11-21 KR KR1020047007652A patent/KR100615844B1/ko not_active Expired - Lifetime
- 2002-11-21 PT PT02803562T patent/PT1457498E/pt unknown
- 2002-11-21 US US10/496,200 patent/US7022676B2/en not_active Expired - Lifetime
- 2002-11-21 DE DE60218064T patent/DE60218064T2/de not_active Expired - Lifetime
- 2002-11-21 AU AU2002366037A patent/AU2002366037B2/en not_active Expired
- 2002-11-21 AT AT02803562T patent/ATE353336T1/de active
2004
- 2004-06-21 NO NO20042601A patent/NO328611B1/no not_active IP Right Cessation
2007
- 2007-05-03 CY CY20071100587T patent/CY1106557T1/el unknown

Also Published As

Publication number	Publication date
HK1076114A1 (en)	2006-01-06
KR100615844B1 (ko)	2006-08-25
BR0214299A (pt)	2004-12-14
ATE353336T1 (de)	2007-02-15
KR20050044541A (ko)	2005-05-12
DE60218064T2 (de)	2007-11-15
EP1457498A1 (en)	2004-09-15
ES2281567T3 (es)	2007-10-01
CA2468039A1 (en)	2003-05-30
AU2002366037B2 (en)	2005-11-03
MXPA04004805A (es)	2004-08-11
CN1612892A (zh)	2005-05-04
NO328611B1 (no)	2010-03-29
EP1457498B9 (en)	2009-09-02
US20050004041A1 (en)	2005-01-06
EP1457498A4 (en)	2005-10-19
WO2003044044A1 (en)	2003-05-30
NO20042601L (no)	2004-08-18
EP1457498B1 (en)	2007-02-07
NZ533544A (en)	2005-02-25
CA2468039C (en)	2011-01-04
CN1240711C (zh)	2006-02-08
JP3816921B2 (ja)	2006-08-30
DE60218064D1 (de)	2007-03-22
AU2002366037A1 (en)	2003-06-10
CY1106557T1 (el)	2012-01-25
PT1457498E (pt)	2007-05-31
US7022676B2 (en)	2006-04-04
JPWO2003044044A1 (ja)	2005-03-10

Publication	Publication Date	Title
DK1457498T3 (da)	2007-06-04	Hidtil ukendt peptid med angiotensinkonvertaseinhibitorisk virkning
ATE310009T1 (de)	2005-12-15	Reaktionssysteme zur herstellung von n- (phosphonomethyl)glyzin verbindungen
DE60330376D1 (de)	2010-01-14	Defructosylierungsverfahren
UY27585A1 (es)	2003-06-30	Cis - imidazolinas
ATE462006T1 (de)	2010-04-15	Isoform des vegfs
CY1111225T1 (el)	2015-06-11	Νεα πεπτιδια ως αναστολεις πρωτεασης νs3-σερινης ιου ηπατiτιδας c
DK1178958T3 (da)	2004-06-21	N-cyanomethylamider som proteaseinhibitorer
SE0100903D0 (sv)	2001-03-15	Compounds
BRPI0414593A (pt)	2006-11-07	derivados de ácido sulfonamida substituìda-indol-2-carboxìlico como inibidores de pai-1
DE60228071D1 (de)	2008-09-18	Spiropyrazol-verbindungen
ATE382604T1 (de)	2008-01-15	Aminosäure-derivate als hiv aspartyl-protease- inhibitoren
NO20063064L (no)	2006-09-01	Ny anvendelse av peptidforbindelser for behandling av sentralneurotisk smerte
ES2422081T3 (es)	2013-09-06	Péptido Ser-Ser-Ser-Arg y sus utilizaciones medicinales
HRP20080057T3 (en)	2008-02-29	9,10-alpha,alpha-oh-taxane analogs and methods for production thereof
SE0103710D0 (sv)	2001-11-07	Compounds
ATE323722T1 (de)	2006-05-15	Antimikrobiell wirkendes peptid
SE0101082D0 (sv)	2001-03-27	Novel use
IT1317722B1 (it)	2003-07-15	Procedimento per la produzione di gas di sintesi.
EA200400438A1 (ru)	2004-10-28	Применение ирбесартана для изготовления лекарств, которые пригодны для предупреждения или лечения лёгочной гипертонии
IT1318575B1 (it)	2003-08-27	Procedimento integrato per la produzione di cumene.
NO20051867L (no)	2005-04-18	Fremgangsmate for fremstilling av intermediater
SE9800865D0 (sv)	1998-03-16	New Process
ITTO20010237A0 (it)	2001-03-15	Procedimento per la preparazione di un idrolizzato proteico utile perl'impiego come fertilizzante.
ATE328082T1 (de)	2006-06-15	Verkürztes bard1 protein und dessen diagnostische und therapeutische anwendungen
DK1096951T3 (da)	2002-10-21	Anvendelse af bromelainproteaser til inhiberingen af blodkoaguleringen