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DK1448993T3 - Detektering af autoantistoffer reaktive med antigene molekyler af pankreas-öceller - Google Patents

Detektering af autoantistoffer reaktive med antigene molekyler af pankreas-öceller

Info

Publication number
DK1448993T3
DK1448993T3 DK02779738T DK02779738T DK1448993T3 DK 1448993 T3 DK1448993 T3 DK 1448993T3 DK 02779738 T DK02779738 T DK 02779738T DK 02779738 T DK02779738 T DK 02779738T DK 1448993 T3 DK1448993 T3 DK 1448993T3
Authority
DK
Denmark
Prior art keywords
pancreatic islet
antigenic molecules
detection
antigenic
islet cells
Prior art date
Application number
DK02779738T
Other languages
English (en)
Inventor
Bernard Rees Smith
Jadwiga Furmaniak
Michael Powell
Original Assignee
Rsr Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9926667&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1448993(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rsr Ltd filed Critical Rsr Ltd
Application granted granted Critical
Publication of DK1448993T3 publication Critical patent/DK1448993T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01048—Fusarinine-C ornithinesterase (3.1.1.48)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/03048—Protein-tyrosine-phosphatase (3.1.3.48)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/01—Carboxy-lyases (4.1.1)
    • C12Y401/01015—Glutamate decarboxylase (4.1.1.15)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/916—Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/988—Lyases (4.), e.g. aldolases, heparinase, enolases, fumarase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2496/00—Reference solutions for assays of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK02779738T 2001-11-28 2002-11-26 Detektering af autoantistoffer reaktive med antigene molekyler af pankreas-öceller DK1448993T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0128583.2A GB0128583D0 (en) 2001-11-28 2001-11-28 Detection of autoantibodies indicative of diabetes
PCT/GB2002/005285 WO2003048772A2 (en) 2001-11-28 2002-11-26 Detection of autoantibodies reactive with pancreatic islet cell antigenic molecules and/or insulin

Publications (1)

Publication Number Publication Date
DK1448993T3 true DK1448993T3 (da) 2009-06-22

Family

ID=9926667

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02779738T DK1448993T3 (da) 2001-11-28 2002-11-26 Detektering af autoantistoffer reaktive med antigene molekyler af pankreas-öceller

Country Status (11)

Country Link
US (4) US8129132B2 (da)
EP (1) EP1448993B1 (da)
JP (2) JP2005512056A (da)
CN (1) CN100439920C (da)
AT (1) ATE426166T1 (da)
AU (1) AU2002343076A1 (da)
DE (1) DE60231639D1 (da)
DK (1) DK1448993T3 (da)
ES (1) ES2320427T3 (da)
GB (1) GB0128583D0 (da)
WO (1) WO2003048772A2 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0128583D0 (en) * 2001-11-28 2002-01-23 Rsr Ltd Detection of autoantibodies indicative of diabetes
US7131202B2 (en) * 2004-03-11 2006-11-07 The Gillette Company Cutting members for shaving razors with multiple blades
GB2426581A (en) * 2005-05-27 2006-11-29 Univ Nottingham Immunoassay methods
JP2011106644A (ja) 2009-10-22 2011-06-02 Honda Motor Co Ltd 変速機の油圧制御装置
EP2629797B1 (en) 2010-10-19 2018-05-23 The Regents of the University of Colorado, A Body Corporate Peptides for modulating t-cell activity and uses thereof
US20190263888A1 (en) 2010-10-19 2019-08-29 Op-T Llc Therapeutic peptides and methods for treating autoimmune related disease
EP2631653A1 (en) * 2012-02-24 2013-08-28 Charité - Universitätsmedizin Berlin Identification of modulators of binding properties of antibodies reactive with a member of the insulin receptor family
CN102967704B (zh) * 2012-11-26 2014-05-14 深圳市伯劳特生物制品有限公司 一种用于糖尿病自身抗体6项联检试剂盒
JP6196989B2 (ja) * 2013-02-05 2017-09-13 シスメックス株式会社 １型糖尿病の早期診断マーカーであるｇａｄ抗体の高感度測定方法
CN104098670A (zh) * 2013-04-03 2014-10-15 苏州偲聚生物材料有限公司 多肽、包含该多肽的检测器件和检测试剂盒
CN104098677A (zh) * 2013-04-03 2014-10-15 苏州偲聚生物材料有限公司 多肽、包含该多肽的检测器件和检测试剂盒
CN104560911B (zh) * 2014-12-18 2018-06-05 深圳市新产业生物医学工程股份有限公司 一种融合抗原蛋白质
CN104569425B (zh) * 2014-12-18 2017-02-08 深圳市新产业生物医学工程股份有限公司 一种与酪氨酸磷酸酶抗体特异结合的抗原蛋白质
CN107044977A (zh) * 2016-06-30 2017-08-15 深圳市亚辉龙生物科技股份有限公司 一种酪氨酸磷酸酶抗体化学发光免疫检测试剂盒及其制备方法
US11793854B2 (en) 2019-03-21 2023-10-24 Op-T Llc Methods for reducing symptoms of multiple sclerosis using a six-amino acid long peptide that inhibits CD40-CD150 interaction
EP3953708A1 (en) * 2019-04-12 2022-02-16 Op-T Llc Diagnosis and treatment of autoimmune diseases
EP4135742A2 (en) 2020-04-17 2023-02-22 Op-T Llc Bioactive peptides and methods of use thereof
CN112710839A (zh) * 2020-12-14 2021-04-27 三诺生物传感股份有限公司 一种gad65自身抗体检测试剂盒及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988009933A1 (en) * 1987-06-09 1988-12-15 Walker Laboratories Ltd. Immunoassay method
CN1036080A (zh) * 1988-03-23 1989-10-04 广东省肇庆地区第一人民医院 表面抗原的快速检测法
JPH07507441A (ja) * 1991-11-01 1995-08-24 ジヨスリン・ダイアビーテイス・センター １型真性糖尿病に関連する抗原
MD960317A (ro) 1991-11-19 1998-05-31 Anylin Pharmaceuticals, Inc. Noile peptide-agoniste ale amilinei şi utilizarea lor
US5200318A (en) * 1992-05-13 1993-04-06 Miles Inc. Diagnosis of IDDM with a panel of immunoreagents
EP0701569B1 (en) * 1992-12-03 2008-11-12 The Regents Of The University Of California Improved reagents and methods for the diagnosis and treatment of diabetes and stiff man syndrome
CN1053276C (zh) * 1997-03-11 2000-06-07 中日友好医院 一种检测胰岛细胞抗体的方法
DE19723463A1 (de) * 1997-06-04 1998-12-10 Dade Behring Marburg Gmbh Immunchemische Bestimmung von multivalenten Analyten
GB9719357D0 (en) * 1997-09-11 1997-11-12 Ortho Clinical Diagnostics Immunoassay Utilizing Two Incubations With Labelled Antigen
US6187563B1 (en) * 1998-08-07 2001-02-13 Yale University βIV-spectrin-polypeptides and nucleic acids encoding same
CN1283794A (zh) * 2000-07-12 2001-02-14 华西医科大学 同步快速测定多项免疫指标技术
GB0128583D0 (en) * 2001-11-28 2002-01-23 Rsr Ltd Detection of autoantibodies indicative of diabetes

Also Published As

Publication number Publication date
CN100439920C (zh) 2008-12-03
JP2005512056A (ja) 2005-04-28
EP1448993A2 (en) 2004-08-25
DE60231639D1 (de) 2009-04-30
US20160356771A1 (en) 2016-12-08
ATE426166T1 (de) 2009-04-15
WO2003048772A3 (en) 2003-10-16
US20120225955A1 (en) 2012-09-06
WO2003048772A2 (en) 2003-06-12
US9435797B2 (en) 2016-09-06
AU2002343076A1 (en) 2003-06-17
US8129132B2 (en) 2012-03-06
US20160356772A1 (en) 2016-12-08
CN1585900A (zh) 2005-02-23
GB0128583D0 (en) 2002-01-23
ES2320427T3 (es) 2009-05-22
US10488410B2 (en) 2019-11-26
US20050019837A1 (en) 2005-01-27
JP2009265109A (ja) 2009-11-12
JP5711449B2 (ja) 2015-04-30
US10481156B2 (en) 2019-11-19
EP1448993B1 (en) 2009-03-18

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