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DK1303635T3 - Fremgangsmåde til selektiv overlevelse eller selektiv vækst af en målcelle ved anvendelse af et konjugat til terapi og/eller diagnostik - Google Patents

Fremgangsmåde til selektiv overlevelse eller selektiv vækst af en målcelle ved anvendelse af et konjugat til terapi og/eller diagnostik

Info

Publication number
DK1303635T3
DK1303635T3 DK01960279T DK01960279T DK1303635T3 DK 1303635 T3 DK1303635 T3 DK 1303635T3 DK 01960279 T DK01960279 T DK 01960279T DK 01960279 T DK01960279 T DK 01960279T DK 1303635 T3 DK1303635 T3 DK 1303635T3
Authority
DK
Denmark
Prior art keywords
target cell
conjugate
selective
present
diagnosis
Prior art date
Application number
DK01960279T
Other languages
English (en)
Inventor
Patrice Soumillion
Jacques Fastrez
Original Assignee
Univ Catholique Louvain
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Catholique Louvain filed Critical Univ Catholique Louvain
Application granted granted Critical
Publication of DK1303635T3 publication Critical patent/DK1303635T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6815Enzymes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK01960279T 2000-06-21 2001-06-07 Fremgangsmåde til selektiv overlevelse eller selektiv vækst af en målcelle ved anvendelse af et konjugat til terapi og/eller diagnostik DK1303635T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00870139 2000-06-21
PCT/EP2001/006439 WO2001097854A2 (en) 2000-06-21 2001-06-07 Method for the selective survival or selective growth of a target cell by the use of a conjugate, its use in therapeutics and/or diagnostics

Publications (1)

Publication Number Publication Date
DK1303635T3 true DK1303635T3 (da) 2007-06-04

Family

ID=8175770

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01960279T DK1303635T3 (da) 2000-06-21 2001-06-07 Fremgangsmåde til selektiv overlevelse eller selektiv vækst af en målcelle ved anvendelse af et konjugat til terapi og/eller diagnostik

Country Status (8)

Country Link
US (1) US6969593B2 (da)
EP (1) EP1303635B1 (da)
AT (1) ATE354669T1 (da)
AU (1) AU2001281814A1 (da)
DE (1) DE60126776T2 (da)
DK (1) DK1303635T3 (da)
ES (1) ES2282281T3 (da)
WO (1) WO2001097854A2 (da)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6451995B1 (en) 1996-03-20 2002-09-17 Sloan-Kettering Institute For Cancer Research Single chain FV polynucleotide or peptide constructs of anti-ganglioside GD2 antibodies, cells expressing same and related methods
CN1259875A (zh) 1997-06-11 2000-07-12 伦敦大学药学院 含有与前体药物结合的抗体-酶偶联物的药物组合物

Also Published As

Publication number Publication date
US20030099658A1 (en) 2003-05-29
AU2001281814A1 (en) 2002-01-02
WO2001097854A3 (en) 2002-04-11
EP1303635A2 (en) 2003-04-23
WO2001097854A2 (en) 2001-12-27
ES2282281T3 (es) 2007-10-16
US6969593B2 (en) 2005-11-29
DE60126776D1 (de) 2007-04-05
ATE354669T1 (de) 2007-03-15
DE60126776T2 (de) 2007-10-31
EP1303635B1 (en) 2007-02-21

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